1

.. 2545

..
2537

.. 2545
1.
..
2537 12
2.

2.1 .. 2538
2.2
2.3
3.
3.1

1)
2)

/

3)
4)

5)

6)

7)

8)
3.2
/
4.

3
4.1
4.2

4.3

4.4

4.5

5.
5.1
5.2 /
5.3

..
2545

.. 2545

1:

1.
2.

1. /

4
2.
/
3.

Table of Specifications
1.
1.1
1.2
1.2.1
1.2.2 (percentage labeled amount)
1.3
1.3.1 (SD, RSD),
(linearity), (correlation coefficient),

1.3.2 precision accuracy
1.3.3 t-test, F-test
2.

2.1
2.1.1

2.1.2
(polymorphism) eutectic mixture

2.2
2.2.1

2.2.2

2.3

5
2.3.1 -
2.3.2
2.3.3
2.3.4
2.3.5
2.3.6 (sterilization)
(aseptic techniques)
2.3.7 (pharmaceutical necessities)

2.3.8

2.3.9 GMP
2.3.10
2.3.11 (biotechnology)

2.3.12
3.
3.1 (physical pharmacy)

3.1.1 (cosolvency) (salt
forma- tion) (complexation)
(micelle formation)
3.1.2 (tonicity adjustment) sodium chloride equivalent
method White-Vincent method isotonic buffered diluting solutions
3.1.3 pH (solubility) (degradation)
(absorp- tion) pH pH
3.1.4 (incompatibility)

6
3.1.5 (stability)

(stability test) (shelf-life)
3.2
(pharmaceu- tical necessities)
3.3
-
-
-
-
-

-
-


3.1 (powders) (granules) (hard capsules)
(soft capsules) (tablets) (coated tablets)
3.2 (waters) (syrups)
(elixirs) (spirits)
3.3 (colloids) (mixtures)
(suspen- sions) (emulsions) (lotions) (liniments) (creams)
(ointments) (pastes) (gels) (suppositories)
3.4 (eye, ear, nose and throat preparations)
3.5
3.6 (controlled released products)
(drug delivery systems)
3.7 tinctures, fluidextracts extracts

1. /
2.
3.

7
4.
/
5.

2:
/

1.
2.
3.

Table of Specifications
1.

2.
2.1
2.2
2.2.1
2.2.2
2.2.3
2.2.4
2.2.5
2.2.6 Pharmacoeconomics
2.2.7 Pharmacoepidemiology
3.
3.1

8
3.2

3.3

3.4
3.5
4.

4.1
4.1.1
4.1.2
4.2 (biopharmaceutics)
(pharmacokinetics) (pharmaceutics)
4.2.1 (In vitro dissolution test)
4.2.2 (bioavailability)
(bioequivalence)
4.2.3 (pharmacokinetic
parameters) (absorption rate) (peak
concentration) (peak time) (AUC)

4.2.4 (dosage form)
4.2.5

(route of administration)

4.2.6

4.2.7
5.
5.1
5.2

9
5.3
3:

1.
2.

3.
4.

5.



Table of Specifications
1.
2.
2.1
2.2
2.3
2.4 alligation medial alligation alternate
2.5
2.6 millimole, milliequivalent milliosmole
2.7 (dosage)
3.
3.1
3.2
3.3 aliquot Method stock Solution
3.4

10
3.5
3.6
4.
4.1
4.2

4.3
4.4
4.5



(intravenous admixtures)
(antiseptic solution)
/
(reconstitution)

1.
1.1



1.2 mineral oil glycerin W/W
1.3
1.4 3 , , Mineral oil

1.5 geometric dilution

slab
lactose
1.6
1.7
1.8
1.9 levigate ointment cream slab

11
1.10 Calibrate
0.8 ml 10 ml dropper
2. aliquot
3.
4.
4:

1.
2.
3.

1.
2.

Table of Specifications
1.
1.1
/ ( 1)
1.2 (drug related problems) ( 2)
1.3
2.
2.1

2.2

12
2.2.1

2.2.2
2.2.3
2.3
3.

3.1
3.2
3.2.1 /
/

3.2.2
3.2.2.1
3.2.2.2 /

3.2.3

3.3


4.

1.

13

2.

2.1

2.2


5:

1.
2.
3.


Table of Specifications
1.

( 3)
(rational drug use) (drug use
evaluation)
2. /
2.1
2.2
3 4 3
3.

14
4.

4.1
4.2

( 2)

1. ( 4)

()



2.

2.1 FBS, BP, cholesterol

2.2
2.3
2.4
2.5
2.6 /
3.
3.1
3.2
3.3
3.4
3.5
3.6
4.

15

( ORS)
(inhalations)


5. Drug Identification

6. ...
6:

1.
2.
3.

1.

2.

Table of Specifications
1. ( 2)
2.
3.
4.

5.

16
6.
7. /
7.1 (non-compliance to drug therapy regimen)
7.2
7.3

7.4
8.
/

1.

1.1
1.2
2.


2.1
2.2
2.3
7:

1.
2.

17
3.

1.
2.
Table of Specifications
1. (drug information
service, DIS)
2. DIS
3.
4.
5.

6.
7.


8.
9.

1.
1.1
1.2
1.3
1.4

1.5 /
1.6
8:

18

1.


2.

3. /


Table of Specifications
1.
1.1
1.2

1.3


1.4
1.5

1.6

1.7

1.8
2.
2.1

19
2.2

3.
3.1
3.2

3.3

/ /
3.4


3.5

1.


2.

1


/
1.
2.
3.
4.
5.

20
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28. Allergic rhinitis
29.
30.
31.
32.

21

2

(drug related problems)
1. (untreated indication)

1.1
1.2
1.3
1.4
1.5
2. (improper drug selection)


2.1
2.2
2.3
2.4
2.5
2.6
2.7
3. (subtherapeutic dosage)

3.1
3.2
3.3
3.4
3.5
3.6
3.7
3.8

22
4. (overdosage)

4.1
4.2
4.3
4.4
4.5
4.6
4.7
4.8
4.9
5. (failure to receive medication)

5.1
5.2
5.3
6. (adverse drug reaction)

6.1
6.2
6.3
6.4
6.5 (idiosyncrasy)
6.6
7. (drug interaction)

7.1
7.2
7.3

23
8.
(invalid
indication)
8.1 (drug abuse)
8.2
8.3

1.
1.1. (cardiovascular disorders)
1.2. (respiratory disorders)
1.3. (gastrointestinal disorders)
1.4. (renal disorders)
1.5. (neurologic disorders)
1.6. (psychiatric disorders)
1.7. (endocrine and exocrine disorders)
1.8. (gynecologic and obstetric disorders)
1.9. (immunologic disorders)
1.10 (bone and joint disorders)
1.11 (eyes, ears, nose and throat disorders)
1.12 (dermatological disorders)
1.13 (hematologic disorders)
2. (infectious disorders)
3. (oncologic disorders)
4. (nutritional disorders)

24

1.

1.1 antihistamines, decongestants, antitussives, bronchodilators, mucolytics
1.2 antacids, H2-antagonists, antidiarrheals, laxatives
1.3 analgesics, antimigraines
1.4 contraceptives
1.5 non-steroid antiinflammatory drugs (NSAID), muscle relaxants
1.6 antipruritics, antiacnes, sunscreens
1.7 iron supplement, folic acid
1.8 antibacterials, antifungals, antiparasitics, antiseptics
1.9 calcium supplement, vitamins
1.10 demalotological products
1.11 EENT Preparations
1.12 20
2.
2.1 diuretics, -blockers, calcium antagonists, angiotensin converting enzyme
inhibitors (ACEI)
2.2 antidiabetics, antithyroids, antihyperlipidemics
2.3 steroids
2.4 antimalarials, antivirals, antituberculous agents
2.5 anticancers
2.6 vaccines

25

, , ,
(1
)

2540


..2540(2)


4



5


4.


4.1
4.2

4.3
4.4

( )


4.5
4.6

26
4.7

4.8
1)
2)
3)
4) (Side effect) ( ) (Adverse Drug
Reaction)
5)
6)
4.9
4.10
4.11

5.
5.1

5.2
5.3

5.4

5.5
5.6


5.7

5.8



5.9

27
1)
2)
3)
4)

(Side effect) ( )
(Adverse Drug Reaction)
5)
6)
5.10
5.11



6

28

1.




2.
2.1





2.2

2.3 :
2.3.1
- ,

-
-

29
-
-
-
2.3.2


3.

1


1)

2)
3)
4)
5)
6)
7) /
2

1)
2)
3)
4)
3

4
1)
2)

(1)

30
(2)
(3)
(4)
(5)
(6)
(7)

3)
5




1)
-
-
(Show and Tell)
2)
3)
4)
5)

31