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The Origin of Life
The Origin of Life
Metabolize – LIFE
get food,
energy; release
waste Have a structure
– separate
insides from
outside
Big questions:
• How did all these functions ever come
together in a cell?
• Which came first?
Major theories
• Replicators first: Genes → proteins → cells
– Life began when primitive RNA emerged from
primordial soup with the ability to make copies of itself
– Main problem: Sunlight, water and O2 keeps breaking
everything down, so speed (catalysis) is crucial
– Originally self-catalyzed, genes later began to
synthesize proteins, or control them
– Clusters later developed a membrane for protection
• Metabolizers first: Amino acids → proteinoid
chains → cells → genes
• Structure first: Cells (Coacervates) → enzymes
(proteins) → genes
No clear winner among the three theories
Other Proposed Origins
• Deep ocean – all life came from
superheated undersea hydrothermal vents
– Deep-ocean vents mimic early conditions on
earth. Since life can survive there, maybe it
formed there
• E.T.: Life came from outer space, where
conditions are more favorable to formation
– Delivered to earth via meteorites, comets
• Complex organic molecules formed on
non-organic replication platform: silicate
crystals in clay
– Minerals catalyzed, provided templates
– Life later freed itself from mineral platforms
So What Do We Know for Sure?
• Creating life is hard, but it had time
– Took about 1 billion years after earth’s formation 4.6 BYA
to form first cells
– Another 3 billion years to create multicellular organisms
• Once life formed it occupied everything
– Life even changed the earth to be more habitable: the
ozone layer
– Numbers and types grew exponentially
– Today: life is present nearly everywhere we look
• A constant battle: between molecules, then cells,
then individuals, etc.
– Change was the rule for survival: evolve or die
• Like it or not, our ancestors were slime