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UNIT I
ELECTRO-PHYSIOLOGY
AND BIO-POTENTIAL
RECORDING
PREPAIED
BY
SHAIJURAJAN
UNIT I
ELECTRO-PHYSIOLOGY
AND BIO-POTENTIAL
RECORDING
TheoriginofBiopotentials;Biopotential
electrodes,biologicalamplifiers,ECG,
EEG,EMG,PCG,EOG,leadsystemsand
recordingmethods,typicalwaveformsandsignal
CELLSSTRUCTUREAND
FUNCTION
Whatiscell?
Basiclivingunitofthehumanbody.
Eachorganinahumanbodydifferentcells.
Eachcellsareresponsibleforoneparticularfunction
Entirebodycontain100trillioncells.
Allcellshaveabilitytoreproduceanewcellswheneveraparticulartypeare
destroyed.
Eachcellconsistsofacentrallylocatednucleus
(cellcore)
Thecellcoresurroundedbycytoplasm(cell
body)
Thenucleusisseparatedfromcytoplasmby
nuclearmembrane.
Thedifferentsubstancethatmakeupthecellare
collectivelycalledastheprotoplasm.
Water:fluidinthecellconcentation
70to80%,usedsolventforallchemicalin
ordertoproducethechemicalreaction.
Electrolyte:
Magnesium
Potassium
Phosphate
Bicarbonateandsmallquantityofcalcium,
chloride,sodium.
Protein:concentation1020%
Twotypesofprotein:1)structuralproteinarelong,thin
filament,providecontractilemechanismofallmuscle.
2)globularwillprovidetheenergyforcellfunction
Lipids:solubleinfacts,solventandinsolubleinwater.
Carbohydrates:nutritionofcell.Itisstoredinthecell
intheformofglycogenandtheyusedsupplythecells
energy
Cytoplasm:
CytoplasmisfilledwiththeCytosol,clearfluidportion
ofcytoplasminwhichthelargeparticlesare
dispersed.
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RIBOSOME:Ribosomesareminutegranular
particlesinthecytosolandtheyarecomposedwith
mixtureofRNA+proteins.
LYSOSOMES:theseareusedindigestivesystem.
MITOCHONDRIA:
Itisotherwisecalledpowerhouseofthecell
Mitochondriaextractsenergyfromnucleusand
oxygen.
MitochondriaalsocontainsDNA.
DNAisresponsibleforreplicationofthecell.
LargequantitiesofDNAarecalledgenes
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Sizeofhumancellis510m
TRANSPORTOFIONSTHROUGHTHE
CELLMEMBRANE
Twofluidsplayamajorroleinthe
transportationofions.theyareICFandECF
ICFintracellularfluid:thefluidwhichlies
insidethecellmembrane
ECFintracellularfluid:thefluidthatlies
outsidethecellmembrane.
Thecorrectconcentrationofionsare
necessaryfornormalfunctionofhumancell
andhumanbody.
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