Pharmaceuticals

General information

Norit 'leading in purification'

Norit leading in purification develops and applies state-of-the-art purification technologies to help society, through our clients, meet environmental, health, and safety challenges, and work towards a sustainable future. The Norit Group, headquartered in The Netherlands, supplies consumables, components, systems, and solutions, based on proprietary technology in every step of the water and beverage value chains. More than 8 percent of the worlds population - over half a billion people - already consumes water purified by Norit! Norits activated carbon, membranes, pumps, aseptic and hygienic valves, carbon dioxide systems, and quality control equipment rank among the worlds best. Norit offers global coverage with research and development, engineering, and manufacturing facilities in seven countries. A network of dedicated Norit sales and service centers, business partners, and distributors serves customers in more than 150 countries around the world. No following. Norit. Just leading.

Norit Activated Carbon

The Norit Group consists of a number of companies that each has its own specific area of expertise. Each Norit company is a respected expert in its field, maintaining a leading market position. Suffice it to say that synergy and cross-selling are the key drivers of Norits successful growth strategy.

Activated carbon offers unique adsorption

One of the business units is Norit Activated Carbon. Activated carbon is used for the purification of a wide range of substances in all kinds of industries. In fact, virtually every product around the world manufactured today has been improved upon at least once by the use of activated carbon. Norit Activated Carbon is the worlds number one supplier of activated carbon and related services. Main market segments are potable water, food, beverage, reactivation services and decolorizing of pharmaceutical products. In addition, activated carbon is also used as an Active Pharmaceutical Ingredient (API) for pharmaceutical products. The highest purity Pharmaceutical products have to be ultra-pure and fully traceable. Activated carbon has a very high adsorption rate for a wide range of molecules, varying from odorous compounds and small chemical molecules to dark colored bodies, bacteria and unwanted substances in the gut. The ability to control the activation process and the purity of the activated carbon allows Norit Activated Carbon to supply a customized fit. Norit Activated Carbon produces Pharmacopoeia grades (PhEur and USP) of activated carbon. The highest quality activated carbon available results in an overall improvement and efficiency of products. High-quality products increase the consumers trust in clinical outcome.

The usage of medicinal coal for human is known all over the world and experiences a long history.

How it all began

A long time ago, in the Golden Age (during the 17th century when Dutch trade, science and art were among the most acclaimed in the world), when most international cargo was transported by ships, an important discovery was made. After a big ship fire, several water barrels were damaged, but still usable. During the next voyage it was noticed that people who drank out of these charred barrels suffered less from infections and diarrhea. Thus, people understood one of the many benefits of carbon: water purification!

General information

Norit Activated Carbon

Highest quality (Pharmacopoeia) grades of activated carbon Has been producing and launching pharmaceutical products in co-operation with distributors since 1920 The activated carbon production plant and the pharma plant are both located in Klazienaveen, The Netherlands, and are pharmaceutically certified (GMP) Well respected in more than 30 countries, primarily in Europe, Asia and Australia Norit Activated Carbon is the market leader in every country where the company is active and has developed great knowledge of the market by close relations with distributors Tailor-made solutions for (semi-) finished products and contract manufacturing

Norit Activated Carbon

Product development Line extensions (liquids) New applications (weight control, flatulence) New products Own lab facilities Production Own activated carbon production plant, Klazienaveen, The Netherlands (GMP) Own pharmaceutical production plant, Klazienaveen, The Netherlands (GMP) QA/QC support Distribution/logistics Front desk, production and delivery: +31 33 464 8882 Registration Successful registration support all over the world since 1920 Pharmacovigilance Market development and support Medical Application Manager Account Manager and Business Manager Research/ PMS Pharmacovigilance Medical Application Manager

Tailor-made pharmaceutical solutions

Organization and service specialized in solutions for the gastro-intestinal tract

Today, Norit Activated Carbon produces and sells pharmaceutical products in more than 30 countries with a large distribution for two gastro-intestinal applications: diarrhea and poisoning, both based on proven and natural purification of the gastro-intestinal tract. 1. Diarrhea Diarrhea is a very common and potentially deadly health problem. According to the World Health Organization (2006) more than 4 million children die every year from the consequences of diarrhea. Treatment of acute diarrhea is generally divided into the following therapies: activated carbon, oral rehydration (ORS), loperamide and others. Activated carbon that purifies the gut and cures diarrhea, is a safe therapy even for children, and can be used for all types of acute diarrhea. 2. Poisoning Common causes for oral intoxication worldwide are: medication overdose, fungus or other toxic substances. The proven and effective therapy for many toxic substances is a high dosage of activated carbon (1g/kg bodyweight). Quick administration of activated carbon limits or totally prevents absorption of those toxic substances in the gastro-intestinal tract. The incidence of poisoning is estimated at 1,560 per 1,000,000 inhabitants, per year.

General information

Innovative applications for common gastro-intestinal health problems

Together with a global distribution network Norit Activated Carbon is constantly looking for new applications. Currently Norit Activated Carbon is developing products for aiding weight management, reducing flatulence and facilitating wound healing. Furthermore, Norit Activated Carbon is extending the product portfolio with new products such as loperamide and probiotics.

Norit Activated Carbon. A constant quality

Highest quality activated carbon guaranteed (Pharmacopoeia grades) Delivery on demand due to on-site production and experienced logistic department Contract manufacturing specializes in handling medicinal activated carbon Local registration support Marketing and sales support (best practices, positioning, marketing communication) Scientific support (Key Opinion Leader Management, literature search, training, research) Exclusive partnership with distributors Partnership model with Account Manager and Business Manager Cross selling opportunities Short decision lines and thorough expertise ensures that Norit Activated Carbon can operate in a flexible and decisive manner

General information

Norit Nederland BV P.O. Box 105 3800 AC Amersfoort The Netherlands T +31 33 4648911 F +31 33 4617429 E info@norit.com I www.norit-ac.com
Please visit our website to obtain information about your local support! Norit Nederland BV reserves the right to make changes in technical specifications at any time in case the company considers this necessary (to guarantee safety of its products).
Ph A 7-2008