Act 5 Chapter 4

Part 1 Nodes Description Appearance

No. of Paths 5
Common Nodes Vigor Every 15 seconds after the start of the fight, Regenerate for 5.4.1
Life Transfer 50% of Base Health over 5 seconds. The timer refreshes 5.4.3
Feats of Power when this Champion reaches intervals of 25% missing 5.4.6
Vigor Health.
Rage
Bane
Part 2
No. of Paths 5
Common Nodes Resistor When struck with an Energy or Physical Attack, activate a 5.4.2
Biohazard corresponding Resistance Buff increasing respective 5.4.3
Masochism Resistance by 20%. When an Energy Resistance Buff is 5.4.6
Resistor activated, remove a Physical Resistance Buff, and vice-
versa.

Part 3
No. of Paths 6
Common Nodes Bane When Blocking an attack, activate an Armor Up Buff, 5.4.5
Vigor boosting Armor by 25%. Upon reaching 5 stacks of Armor
Brute Force Up generated by Explosive Personality, Armor Up stacks
Explosive Personality explode and remove 25% of opponent's Health.
Resistor

Part 4
No. of Paths 6
Common Nodes Masochism When above 1 Bar of Power, gain a Fury Buff. When above 5.4.1
Breakthrough 2 Bars of Power, gain a Precision Buff. When at 3 Bars of
Rage Power, Gain a Cruelty Buff.
Feats of Power
Brute Force
Biohazard
Recovery

Part 5 Damage taken in a single hit is capped at 2.5% of Max 5.4.1

No. of Paths 6 Health. When damage cap is reached, gain a Fury Buff. 5.4.4
Common Nodes Immunity Rage Upon reaching 5 Fury Buffs activated by Rage, attacks 5.4.6
Biohazard become Unblockable.
Caltrops
Explosive Personality
Cornered
When struck, 20% chance to inflict Bleed, dealing 100% of 5.4.2
Part 6 Attack as direct damage over 7.5 seconds. When Blocking 5.4.4
No. of Paths 8 an attack, 50% chance to inflict Poison, dealing 100% of 5.4.5
Biohazard Attack as direct damage over 7.5 seconds.
Common Nodes Resistor 5.4.6
Rage
Vigor
Bane
Biohazard
Buffet
100% Power Gain
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5.4.1
[6] Vitality [7] Life Transfer [8] Power [9] Rage [10] Poison and Bleed

Vigor Life Transfer Feats of Power Rage

Every 15 seconds after the start of the fight, Damage taken in a single hit is capped at 2.5% of
When above 1 Bar of Power, gain a Fury Buff.
Regenerate for 50% of Base Health over 5 seconds. Max Health. When damage cap is reached, gain a
When above 2 Bars of Power, gain a Precision Buff.
The timer refreshes when this Champion reaches Fury Buff. Upon reaching 5 Fury Buffs activated by
When at 3 Bars of Power, Gain a Cruelty Buff.
intervals of 25% missing Health Rage, attacks become Unblockable.

Tip: use Arc, Guilly, Loki (maybe). Have never tried

Tip: use DoT champs or Nullifiers
but Nullify, Stagger, Heal Block should work as well

VP Recovery Karnak Critical Mammu Outlast BW Godslayer Carnage Mystic Ward, En. Bleed
Angela Mystic Ward Loki Buff Duration Mordo Un. L2 Rhino Aggressive Arc En. Bleed, En. Poison
DV Physical Res. GP Stupefy Nebula Limber MM En. Fury AM En. Weakening, En. Poison
Wolverine En. Abilities Yondu Debilitate Magik Shatter Pun Rolling Thunder Abom Stun Immunity, En. Poison
X-23 Bane of Damballah GR 100% Power Gain Groot Heavy-Handed, Armor Guilly En. Crits, En. Bleed
SIM En. Armor Up Falcon Immunity KG Critical DPX Bloodletting, En. Bleed
Blade En. Bleed Beast Energy Res. Gami Resonance Cascade
DP Replicate OGV 90% Armor SL Critical
Quake Stun Immunity

Middle
1 2 3 4 5
Thor CAWWII Juggs DD Spider-Gwen
Doc Ock Bane Storm Bane DS Hulk Bane IF Bane
Cable Bane

Boss - Punisher 2099

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5.4.2
[4] Resilience [5] Poison and Bleed [6] Masochism [9] Rage [10] Power

Resistor Biohazard Masochism Rage

When struck with an Energy or Physical Attack,
activate a corresponding Resistance Buff
increasing respective Resistance by 20%. When an
Energy Resistance Buff is activated, remove a
Physical Resistance Buff, and vice-versa
When struck, 20% chance to inflict Bleed, dealing
100% of Attack as direct damage over 7.5 seconds.
When Blocking an attack, 50% chance to inflict
Poison, dealing 100% of Attack as direct damage
over 7.5 seconds.

Tip: spam DV L1, MS L2, or Magik L3; Nullifiers Tip: bring a bleed-immune champ then bait and
would work as well; [from u/Willie6541] stun-lock intercept (NEVER HIT BLOCKS) or bring a double- Tip: use DoT champs or Nullifiers
to victory with duped Ronan immune champ; Blade with GR is also great

IM Armor Up Abom Flare Spark Insecurity BB Godslayer, En. Fury SL Cornered, En. Fury
IP En. Armor Break Fixit Stacked Deck Doc Ock Mirror Image Hulk Rolling Thunder, En. Fury OGV Power Start 1, Limber
LC 90% Armor

Middle
1 2 3
Masochism

Hood Breakthrough, Stupefy YJ En. Weakening Hypes Plagued Mind, Pessimist

CAWWII Bloodletting, En. Abilities CW Stun BW Critical Damage, Critical Rate
GP Bloodletting, En. Bleed Elektra Stun Mammu Shatter, Poison Immunity
BP En. Bleed, Critical WS Un. L1 GR Burden of Might, Spirit of Justice
Duck Energy Res. En. Fury Nebula Fury, Recovery
Wolvie En. Bleed, Outlast
Ultron En. Bleed, Limber

[A] Resilience [B] Poison & Bleed Masochism [A] Rage [B] Power

Rhino Heal Block, Aggressive Mags En. Bleed, 90% Armor HB En. Armor Up Drax En. Fury, Stun HE 100% Power Gain, Buffet
DS Physical Res., Energy Res. X-23 En. Bleed, Poison IF En. Crits KP Aggressive, King of Hell's Kitchen DV Kinetic Reactor, Bane of Damballah

Ambush Ambush Ambush

AM KG thanks to u/the-real-simula67 Karnak
Cyke

Boss - MS

Note: Bring a bleed-immune champ or Blade

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5.4.3
[Left] Bane, Power [Center] Brute Force, Vitality [Right] Resilience, Rage

Vigor Resistor

When struck with an Energy or Physical Attack, activate a corresponding Resistance Buff increasing
Every 15 seconds after the start of the fight, Regenerate for 50% of Base Health over 5 seconds. The
respective Resistance by 20%. When an Energy Resistance Buff is activated, remove a Physical
timer refreshes when this Champion reaches intervals of 25% missing Health
Resistance Buff, and vice-versa

Tip: spam DV L1, MS L2, or Magik L3; Nullifiers would work as well; [from u/Willie6541] stun-lock to
Tip: use Arc, Guilly, Loki (maybe). Have never tried but Nullify, Stagger, Heal Block should work as well
victory with duped Ronan

RHulk Bane, Immunity Fixit Brute Force, Ragnarok Thor Resistor, Immunity
Magik Power Seal, Stun Ange Vigor, Stun Immunity Quake True Strike, Aggressive

YJ Power Drain, Limber Electro Brute Force, Un. L1 Ice Resistor, En. Energy Attacks
Doc Ock Bane, Checkmate DV Vitality Rush, Vigor Beast En. Crits, Replicate
SL 100% Power Gain, True Strike IF 90% Armor, Martial Mastery

[Left] Power [Right] Bane [Up] Vigor [Down] Brute Force [Down] Rage [Right] Resistor

Rogue Power Start 2, Mystic Ward BW En. Crits KP Energy Res. Rhino Fissure UC Godslayer, Critical CW Heavy-Handed
Moonie Cornered, Lunatic AM Energy Res. DS Un. Finale Cap Limber WS En. Fury, Mirror Image Vulture Stun Immunity
GR 100% Power Gain, L3 Bias Spider-Gwen 1% Regen Loki Un. L1 Nebula Stun Juggs En. Fury, Rolling Thunder WM Second Line

Middle
1 2 3
DD Stupefy, Bane Hood Vitality Rush, Resonance Cascade Hulk En. Fury, Bleed Immunity
NC En. Precision, Bane Cable Brute Force, En. Abilities RR 45% Armor, Un. L2
Elektra Power Lock 1, Critical

Mordo - En. Fury, Debilitate

or
Medusa - Immunity, En. Armor Break
Note: Only one champ can be taken down, which removes either Unblockable L1 and L2 (via chest through Mordo) or Enhanced Fury (Medusa) for Hela

Boss - Hela

Note: She gains Unstoppable

From u/Lord__Business add Bane for NC, DD chest after Mordo removes Un. L1 and L2
Medusa removes Enhanced Fury
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5.4.4
[A] Masochism [B] Resilience [C] Rage [D] Brute Force [E] Poison & Bleed [F] Vitality

Masochism Breakthrough Rage Brute Force Biohazard Recovery

When struck, 20% chance to inflict Bleed, dealing
Damage taken in a single hit is capped at 2.5% of
100% of Attack as direct damage over 7.5 seconds.
Max Health. When damage cap is reached, gain a
When Blocking an attack, 50% chance to inflict
Fury Buff. Upon reaching 5 Fury Buffs activated by
Poison, dealing 100% of Attack as direct damage
Rage, attacks become Unblockable.
over 7.5 seconds.

Tip: bring a bleed-immune champ then bait and

Tip: use DoT champs or Nullifiers intercept (NEVER HIT BLOCKS) or bring a double-
immune champ; Blade with GR is also great

AM Adaptive, Pessimist Col En. Armor Up, Outlast GG L1 Bias, Un. L1 Mags En. Abilities WM Un. L1, Second Line, Heavy-Handed Ultron L2 Bias, Un. L2, Stun Immunity
Rhino En. Abilities, Aggressive Groot The Last Stick, Combo Lock Kang L2 Bias, Un. L2 Spark Arc Converter Medusa En. Bleed, Fissure, Fury SIM En. Armor Up, En. Armor Break, En. Energy Attack
RHulk Physical Resist, Outlast Abom En. Poison, En. Abilities XFace Un. L1, Strike Back Raggy Ragnarok IM Arc Overload 2.0, En. Armor Up, En. Armor
GGBreak Un. L1, Parry, En. Abilities
Juggs Stun Immunity, Buff Duration KG Fury, En. Fury Storm L2 Bias, En. Crits Pun L2 Bias
Venom Un. L2, Strike Back HB Outlast, L2 Bias White Mags En. Abilities, Debilitate Karnak Physical Res. Cable True Strike, En. Abilities, L1 Bias DP Rainbow of Power, En. Bleed, L2 Bias
IP Stupefy, L2 Bias Hulk Outlast, En. Fury AV Un. L1, Bloodletting CW En. Armor Up HB Outlast, L2 Bias, En. Armor Up X-23 En. Abilities, En. Bleed, En. Crits
Beast Critical Damage, Critical Rate Iceman Strike Back, Stun Immunity Falcon Un. L1, Outlast Guilly Well of Souls KG En. Poison, L2 Bias, Un. L2 Wolvie En. Abilities, En. Bleed, Critical
OML Mystic Ward, Buff Duration Nebula En. Shock, Defensive OGV Stun Immunity, L1 Bias RR Un. L1
KP King of Hell’s Kitchen, Aggressive Duck En. Armor Up, Mystic Ward Duck L2 Bias, Un. L2 Yondu L2 Bias
Magik En. Abilities, 50% Power Gain Ronan 50% Power Gain
Phoenix Recovery

Hulk

Boss - Modok

Note: Mind his Force Field

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5.4.5
Miles Morales

[A] Immunity or Rage [B] Poison and Bleed [C] Power or Resilience

Biohazard Explosive Personality

When struck, 20% chance to inflict Bleed, dealing 100% of Attack as direct damage over 7.5 seconds. When Blocking an attack, activate an Armor Up Buff, boosting Armor by 25%. Upon reaching 5 stacks of
When Blocking an attack, 50% chance to inflict Poison, dealing 100% of Attack as direct damage over Armor Up generated by Explosive Personality, Armor Up stacks explode and remove 25% of opponent's
7.5 seconds. Health.

Tip: bring a bleed-immune champ then bait and intercept (NEVER HIT BLOCKS) or bring a double-
Tip: use Nullifiers, Staggerers, or just never hit blocks
immune champ; Blade with GR is also great

[Up] Rage [Down] Immunity [Up] Biohazard [Down] Caltrops [Left] Explosive Personality [Right] Cornered

Hulk Fury, En. Fury, Outlast OG Spidey L1 Bias, Critical Damage, Critical Rate Col Heavy-Handed, Mystic Ward, En. Armor Up
Cable True Strike, L1 Bias Duck Buff Duration Moonie En. Bleed
Abom Fury, En. Poison, En. Abilities Raggy Parry, Ragnarok, 50% Power Gain HB Un. L2, En. Armor Up, Outlast Cyke Strike Back, L1 Bias Groot Poison Immunity Loki Buff Duration
Pun Physical Res., Un. L2 Ultron Recovery, En. Bleed, Un. L2 Groot Physical Res., Mystic Ward, Outlast Kang L2 Bias, Un. L2 Spidey Sym Stun Immunity SW En. Abilities
Phoenix En. Fury, Recovery Hypes Fury, Heavy-Hitter, Buff Duration Wolvie Bloodletting, En. Bleed, En. Abilities WM Second Line, L1 Bias UC Buff Duration Quake Debilitate
Venom Anamnesis, Perfect Replication AM Physical Res., Energy Res., Adaptive Cable True Strike, 50% Power Gain, Stun Immunity
AV En. Bleed, Un. L1 BP CW Outlast Doc Ock En. Abilities
Drax En. Fury, En. Bleed NC L1 Bias, En. Bleed, En. Abilities UC Physical Res., En. Fury, Buff Duration Electro En. Crits, Un. L1 Mags Debilitate Arc Un. L1
CM En. Fury, 100% Power Gain Hood L2 Bias, Un. L2 RHulk En. Incinerate Hypes Stun Immunity
DV Bane of Damballah DS L2 Bias
KG Mystic Ward YJ Powersting 3.0 *don't use specials
LC Adaptive Mammu 50% Power Gain

IF

Boss - Mephisto

Note: Stay back when Aura is on

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5.4.6
[Right] YJ
or
[Left] Electro

[A] Resilience or Rage [B] Vitality or Bane [C] Poison & Bleed [D] Power or Buffet

Resistor Rage Vigor Biohazard

When struck with an Energy or Physical
Damage taken in a single hit is capped at
Attack, activate a corresponding
2.5% of Max Health. When damage cap is Every 15 seconds after the start of the fight, Regenerate for 50% of Base Health over When struck, 20% chance to inflict Bleed, dealing 100% of Attack as direct damage over 7.5 seconds.
Resistance Buff increasing respective
reached, gain a Fury Buff. Upon reaching 5 seconds. The timer refreshes when this Champion reaches intervals of 25% missing When Blocking an attack, 50% chance to inflict Poison, dealing 100% of Attack as direct damage over
Resistance by 20%. When an Energy
5 Fury Buffs activated by Rage, attacks Health 7.5 seconds.
Resistance Buff is activated, remove a
become Unblockable.
Physical Resistance Buff, and vice-versa

Tip: spam DV L1, MS L2, or Magik L3;

Nullifiers would work as well; [from Tip: use Arc, Guilly, Loki (maybe). Have never tried but Nullify, Stagger, Heal Block Tip: bring a bleed-immune champ then bait and intercept (NEVER HIT BLOCKS) or bring a double-
Tip: use DoT champs or Nullifiers
u/Willie6541] stun-lock to victory with should work as well immune champ; Blade with GR is also great
duped Ronan

[Left] Resistor [Up] Rage [Right] Vigor [Down] Bane [Left] Biohazard [Up] Poison & Bleed [Right] Buffet [Down] 100% Power Gain

LC Adaptive Hulk En. Fury GG Un. L1 Hypes Stun Immunity VP Buff Duration, Rainbow of Power, Duodenum
BP CWProd Bleed, Armor, Stupefy, En. Bleed Arc En. Abilities, En. Bleed, En. Poison OG Spidey L1 Bias, Un. L1, En. Crits
Abom En. Abilities KG En. Fury Nebula Recovery BP CW 45% Armor Ultron Recovery, Stun Immunity, Un. L2 Mordo Poison, En. Fury, Plagued Mind, Buff Duration
AM Energy Res., Physical Res., All or NothingHood L2 Bias, Un. L2
HB Outlast KP King of Hell’s Kitchen Wolverine En.Bleed CM 50% Power Gain DP En. Bleed, Duodenum Prod, Rainbow of Power
Beast Bleed, Stupefy, Critical Rate, Critical Damage
KP King of Hell’s Kitchen, Gambler’s Fate, Double
Ice or Nothing
Stun Immunity, Strike Back, Critical Rate
DPX Rainbow of Power Venom Perfect Replication X-23 En. Bleed (no Vigor?) Juggs Buff Duration Groot The Last Stick, Combo Lock, Mystic WardHypes Poison, Stun Immunity, 50% Power Gain,WS
En. IncinerateUn. Finale, Bloodletting, En. Bleed
CW 66% Armor RR Un. L1 Angela Mystic Ward Rhino En. Abilities
Rhino Aggressive GP En. Bleed Phoenix En. Fury UC En. Fury
Rogue Limber

Middle
IF TJF Stun, Parry NDD En. Crits, Honed Radar Sense MM 50% Power Gain, En. Fury Thor Enhanced AB, Enhanced Fury NDD En. Crits, Honed Radar Sense Gambit Defensive, Rolling Thunder MM 50% Power Gain, En. Fury
Thor Enhanced AB, Enhanced Fury Gambit Defensive, Rolling Thunder Carnage Strike Back, Heavy-Hitter Carnage Strike Back, Heavy-Hitter

Spark

Boss - Classic Ultron

Note: Parry or land debuffs if the inactive buff is Fury or Armor