VGB-E Series Advanced Film Coaters

DETAILED EXPLANATION ABOUT THE APPLICATION AND MACHINE’S

FUNCTION

Model VGB-E Series Advanced Film Coaters are widely used in pharmaceutical,
herbal, chemical, and confectionary industries. Featuring high quality-advanced design and
manufactured in conformance to the GMP Standard. It is a high-efficiency, energy saving,
minimal waste material and easy to clean. It is ideal equipment for coating tablets, pills,
capsules or candies with organic film, water soluble film, slow and controlled release film
and sugar film.

In pharmaceutical drug delivery of solid oral dosage forms film coatings are
frequently applied. The motivation for coating dosage forms range from cosmetic
considerations (colour, gloss), improving the stability (light protection, moisture and gas
barrier) and making it easier to swallow the tablet. In addition, functional coatings can be
used to modify the drug release behaviour from the dosage form. Depending on the polymers
used it is possible either delay the release of the drug (such as in enteric coatings) or use the
coating to sustain the release of the drug from the dosage form over extended periods of time.
A film coating is a thin polymer-based coat applied to a solid dosage form such as a tablet.
The thickness of such a coating is usually between 20-100 µm. It is possible to follow the
dynamic curing effect on tablet coating structure by using non-destructive analytical
methodologies.
 The additional function of film coating are enhancing flavour, to mask the unpleasant
taste, to control site of dissolution ,to protect components atmospheric degradation such as
oxidation, absorption or evolution of moisture and light to separate incompatible ingredients
and prevent their interaction and to provide a controlled rate absorption.

During film coating the tablets surface to be film coated making continuous orbital
motion within the closed rotating pan under the action of a streamline guide plate. During the
motion, coating solution automatically sprays according to the technological process and
rational technological parameters, at the same time, hot air is supplied from under the bottom
of the layers, so that the coating solution sprayed on the surface of tablet cores will dry
rapidly and evenly thus forming a solid and smooth surface film.

Conclusion

From the last three decades, coating of pharmaceutical formulations including tablet
coating have been subject of remarkable developmental efforts aiming to ensure and enhance
the final product quality. Improvements regarding energy consumption, film distribution,
drying efficiency and continuous processing have contributed to significantly develop this
technology with improved safety profiles. In future there is enormous possibility of
developments in the area of tablet coating to achieve specific benefits.

Coating solution composition may affect the quality of final coated tablets. Some
coating process parameters are affect the final quality of coated tablets so it is necessary to
optimize the coating process parameters for particular equipment and particular film former.
Optimization of composition of film coating solution is also required. Process parameters and
coating composition play an important in coating of tablets. So for getting good final quality
of coated tablet it would be necessary to optimize the parameters. Hence, choosing the right
machine for film coating is important, for example use VGB-E Series Advanced Film Coaters
to receive good result of coating. There are a few type VGB-E Series Advanced Film which
are VGB-40E , VGB-75E , VGB-150, VGB-350 and VGB-600.

The benefits using VGB-E Series Advanced Film Coaters are it can occupied the
capacity of the load within 40 to 600 kg/batch. The value of motor of main machine from
0.75W to 4W, thus low power is consume during the film coating using VGB-E Series
Advanced Film Coaters. Moreover, VGB-E Series Advanced Film Coaters gives a tablet a
less weight and small size which formed the very thin film. The cost of the film coated tablet
is low and better mechanical strength is obtained. Last but not least, it is ideal to use VGB-E
Series Advanced Film Coaters because in film coating engravings are possible on tablet
surface which are not possible in sugar coating.