SPACE GPAT ACACEMY

ANTIEPILEPTICS MOCK TEST-02 12.12.2019

7. The drug which is used for
1. The mechanism of action of myoclonic seizures is:
antiepileptic drugs is : a. Primidone
a. Enhancement of GABA-ergic b. Carbamazepine
(inhibitory) transmission c. Clonazepam
b. Inhibition of excitatory (usually d. Phenytoin .
glutamate-ergic) transmission
c. Modification of ionic conductance 8. The most effective drug in status
d. All of the above . epilepticus in adults is :
2. Which of the following has an a. Carbamazepine
impotent effect on the T-type b. Ethosuximide
calcium channels in thalamic c. Diazepam
neurons? d. Zonisamide .
a. Carbamazepine
b. Lamotrigine 9. Regarding phenytoin:
c. Ethosuximide a. It effects on Ca2+ currents,
d. Phenytoin . reducing the low-threshold (T-
3. The drug which does not produce a type) current
voltage-dependent inactivation of b. It blocks Na+ channels
sodium channels is : c. It inhibits GABA-transaminase,
a. Lamotrigine which catalyzes the breakdown of
b. Carbamazepine GABA
c. Phenytoin d. None of the above .
d. Vigabatrine . 10. Phenytoin is used in the treatment
4. The antiepileptic drug, which of:
produce inhibition of the central a. Petit mal epilepsy
effects of excitatory amino acids is : b. Grand mal epilepsy
a. Ethosuximide c. Myoclonic seizures
b. Lamotrigine d. None of the above .
c. Diazepam 11. Dose-related adverse effect caused
d. Tiagabine . by phenytoin is:
5. The drug which is not used for a. Physical and psychological
partial and generalized tonic-clonic dependence
seizures is : b. Gingival hyperplasia
a. Carbamazepine c. Exacerbated grand mal epilepsy
b. Valproate d. Steven-Johnson syndrome .
c. Phenytoin 12. Granulocytopenia , GI irritation
d. Vigabatrine . and facial hirsutism are possible
6. The drug which is used for absence adverse effects of:
seizures is : a. Phenobarbital
a. Sodium valproate b. Ethosuximide
b. Phenobarbital c. Phenytoin
c. Carbamazepine d. Carbamazepine .
d. Phenytoin . 13. Which of the following does not
induce hepatic microsomal
enzymes