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  • COPD Pathophysio

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    nanette flores dela cruz
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    Celine Veneria F. Dela Cruz is a 68-year-old female with a history of cigarette smoking and noncompliance with medications who presents with productive cough, decreased breath sounds, and localized hyperlucency on chest x-ray. Her white blood cell count is elevated and her arterial blood gas shows hypoxemia, hypercapnia, and respiratory acidosis. She has chronic obstructive pulmonary disease (COPD) resulting from cigarette smoke exposure and inflammation that has led to narrowing of the airways and destruction of lung tissue.

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    COPD-pathophysio

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    Celine Veneria F. Dela Cruz is a 68-year-old female with a history of cigarette smoking and noncompliance with medications who presents with productive cough, decreased breath sounds, and localized hyperlucency on chest x-ray. Her white blood cell count is elevated and her arterial blood gas shows hypoxemia, hypercapnia, and respiratory acidosis. She has chronic obstructive pulmonary disease (COPD) resulting from cigarette smoke exposure and inflammation that has led to narrowing of the airways and destruction of lung tissue.

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    © All Rights Reserved
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    208 views1 page

    COPD Pathophysio

    Uploaded by

    nanette flores dela cruz
    Celine Veneria F. Dela Cruz is a 68-year-old female with a history of cigarette smoking and noncompliance with medications who presents with productive cough, decreased breath sounds, and localized hyperlucency on chest x-ray. Her white blood cell count is elevated and her arterial blood gas shows hypoxemia, hypercapnia, and respiratory acidosis. She has chronic obstructive pulmonary disease (COPD) resulting from cigarette smoke exposure and inflammation that has led to narrowing of the airways and destruction of lung tissue.

    Copyright:

    © All Rights Reserved
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    of 1

    CELINE VENERIA F.

    DELA CRUZ
    COPD PATHOPHYSIOLOGY
    Predisposing factors Predisposing factors
     Old age (68 yo)  Cigarette smoking: 97.5
     Noncompliance to pack years
    maintenance medications

    Mucosal Inflammation
     Productive cough
     Segmenters 90  Decreased tactile fremitus,
     WBC: 15, 000 (NV:5000- Decreased breath sounds
    11,000)  Xray localized hyperlucency at
    the left lower lung field

    Mucosal Edema Muscle contraction Inc. Mucus secretion


    Hypertrophy of bronchial Bronchial smooth muscle Goblet cell hyperplasia
    mucus glands cell hyperactivity

    Narrowing of Bronchospasm Squamous cell


    bronchial Lumen Dec. elastic recoil metaplasia

    Distal Acinar
    Emphysema
    RR 30/min
    Tachypneic
    Xray Positive Rupture of Bullae Dec. AP diameter
    Pneumothorax Left Pneumothorax (wasting)
    chest

    Accumulation of
    Obstruction of airflow secretions

    Decreased Impaired gas Air trapping


    ventilation exchange

    Hypoxemia Hypercapnia ABG


    PCO2: 88
    mmHG
    (NV) 35-45
    mmHg)
    Respiratory acidosis
    Vasoconstriction of
    ABG
     PO2: 50mmHg (NV: 80-
    blood vessels
    100mmHg)
     O2 sat: 88% (NV: >=90%)
    Pulmonary
    hypertension

    Inc workload of R
    side of the heart

    Right sided heart


    failure

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