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Cytology MCQ‐03

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(Biology / Life Sciences MCQ: Multiple Choice Questions in Cytology/Cell Biology)

MCQ on Plasma Membrane Part‐2

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(Sample/Model/Practice Questions for CSIR JRF/NET Life Science Examination, ICMR JRF Exam, DBT BET JRF Exam,, GATE
BT and XL Exam, ICAR JRF NE Exam, PG Entrance Exam, JAM Exam, GS Biology Exam and Medical Entrance Exam)

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1. The cleavage of spectrin network in the cell by the proteolytic enzyme calpane
indicate:
A. Apoptosis

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B. Necrosis
C. Cellular inflammation
D. Phagocytosis

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2. At physiological conditions, cholesterol in the plasma membrane:
A. Increase the durability of plasma membrane
B. Increase the permeability of plasma membrane
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C. Decrease the durability of plasma membrane
D. Decrease the permeability of plasma membrane
A. A, B
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B. A, C
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C. A, D
D. B, D
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3. The molecular basis of MN blood group in human is

A. Difference in the amino acid sequence in the Glycophorin
B. Difference in the carbohydrate sequence in Glycophorin
C. Difference in folding pattern of Glycophorin
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D. Difference in the distributional pattern of band 3 and glycophorin proteins in

the plasma membrane of RBC
4. Which of the following type of movement is least possible for a phospholipid in the
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plasma membrane?
A. Flexion
B. Rotation
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C. Lateral diffusion
D. Flip‐flop
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5. Spectrin‐ankyrin network of plasma membrane is essential for all features of bio‐

membrane except:
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A. Anchoring specific ion channels in the plasma membrane

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B. Anchoring specific ion exchangers in the plasma membrane
C. Anchoring specific ion transporters in the plasma membrane

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D. Anchoring Fo particle of ATP synthase in the plasma membrane
6. An important domain of ankyrin protein which binds to apoptosis inducing proteins
of the cells is:
A. N‐terminal domain

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B. Central domain
C. Death domain
D. C‐terminal

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7. Which of the following is a cytoskeletal protein
A. Glycophorin A
B. Glycophorin B

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C. Spectrin
D. Band 3 protein

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8. The most abundant phospholipid component in the bacterial cell membrane is
A. Phosphatidylethanolamine
B. Phosphatidylserine
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C. Phosphatidylcholine
D. Cholesterol
9. The main function of band 3 proteins in the plasma membrane of RBC is
A. Exchange of chloride ion (Cl‐) with bicarbonate ions
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B. Exchange of K+ ions with Na+ ions
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C. Exchange of H+ ions with biocarbonate ions

D. Exchange of H+ ions with Cl‐ ions
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10. The length of fatty acyl chain in the fatty acids of membrane lipids usually range
from
A. 10 – 15 carbons
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B. 18 – 20 carbons
C. 24 – 30 carbons
D. 28 – 30 carbons
11. Ankyrin proteins have binding site for the _______ subunit of spectrin proteins
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A. Alpha
B. Beta
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C. Alpha and beta

D. Alpha and delta
12. What structural features of a membrane are major contributors to its selective
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permeability?
A. Phospholipid bilayer
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B. Trans‐membrane proteins
C. Glycolipids on the outer surface of the membrane

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D. Peripheral membrane proteins on the inside of the membrane
13. Water can pass the plasma membrane:
A. by simple diffusion only
B. Through aquaporins channel only

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C. By simple diffusion and through aquaporins
D. Water cannot cross plasma membrane
14. The genetic disorder hemolytic anemia is caused by

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A. Mutation in spectrin and ankyrin genes
B. Mutation in band 3 protein of RBC
C. Mutation in Glycophorin A protein of RBC

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D. Mutation in Glycophorin B protein of RBC
15. If the temperature of culture of bacterial is lowered, the cell responds metabolically

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to maintain the fluidity of membrane. This will be achieved by:
A. Introducing more double bonds in the fatty acyl chain of fatty acids
B. Reshuffling the chain between different phospholipid molecule to produce
lipids with two unsaturated fatty acids
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C. Removing double bonds from fatty acids to increase the saturation of fatty
acids
D. Reshuffling the chain between different phospholipids molecules to produce
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lipids with saturated fatty acids
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A. A, B
B. A, C, D
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C. A, D
D. C, D

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choice‐questions‐answer‐key‐explanations/
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