University Of Ahel Albait

College Of Pharmacy

First stage

Practical Of Pharmaceutical Calculation

Simple Solution

Group : A1
Team members : Duaa Aamer , Ola Alaa and Abbas Ziad
Date : March 11, 2019
 Theory

In chemistry, a solution is a special type of homogeneous

mixture composed of two or more substances. The term
aqueous solution is when one of the solvents is water. In
such a mixture, a solute is a substance dissolved in
another substance, known as a solvent. The mixing
process of a solution happens at a scale where the
effects of chemical polarity are involved, resulting in
interactions that are specific to solvation. The solution
assumes the phase of the solvent when the solvent is the
larger fraction of the mixture, as is commonly the case.
The concentration of a solute in a solution is the mass of
that solute expressed as a percentage of the mass of the
whole solution.
Solute :The substance which dissolves in a solution.
Solvent :The substance which dissolves another to form a
solution. For example, in a sugar and water solution,
water is the solvent, sugar is the solute.
Distilled water : is obtained through the process of
evaporation and condensation. Water is heated to
boiling point, changing it to steam and leaving impurities
behind. As the steam cools, it condenses back to water
.This condensate is collected as distilled water _The
heating process kills bacteria and viruses which makes
the water drinkable.

The liquid preparation are cover a high percentage of

pharmaceutical preparation. A solution is a
homogeneous mixture composed of only one phase. In
such a mixture solute is a substance dissolved in another
substance, known as a solvent. WATER
Water is used both as vehicle and as a solvent for the
desired flavoring or medicinal ingredients. Advantages:
Tasteless, odourless, lack of pharmacological activity,
neutral and very cheap.
 Practical Work :

Normal saline preparation :

Rx
Sodium Chloride 0.9 g
Purified Water ad 100 ml

Tools Used :

1. Sensitive balance
2. Wash bottle
3. Beaker
4. Cylinder
5. Glass rode
6. Volumetric flask
7. Filter paper
8. Funnel
 Procedure:

1. The solids has been weighted and transferred into a suitable

container

2. 3/4 (three quarters) of the total volume of the vehicle has

been calculated and subtracted from it the volume of any liquid
component.

3.The resultant volume of the vehicle has been measured and

added to the contents of the container.

4. The solid medicaments has been stirred until it dissolved .

5. The liquid ingredient has been measured and added it to the

container.

6.It has been stirred until it became homogenous.

7. The contents of the container has been transferred to a
suitable measuring cylinder and a sufficient vehicle has been
added to reach the final volume.
8. The mixture has been transferred to a suitable "Dispensing
bottle".
9. A label with the following instructions has been attached :
a. "For Internal Use" (or "For, External Use" if it is)
b. Prescriber name
C. Patient name
d. Directions for use
e. Medication name/compositions
f. Date of dispensing and expiration
 Dıscussion

We have to try to prepare a simple solution (liquid medicine)

have mixing solid material (sodium chloride) after weight 0.9
by sensitive balance, because balance sensor more accurate
than the balance equal arm then we took the material and put
them in Båker, then we have to take the cylinder because it is
more accurate in the measurement of liquids and put the 75
mm of distilled water because tap water contains impurities
and microbes and is undrinkable after we've dissolving the
solid material in distilled using the Baker put solute water
(dissolved) in water (solvent) we have a simple solution and
we developed this solution simple in volumetric flask noticed
that the amount of the solution has become more than the
amount of the solvent before adding dissolved mechanism
due to the effect of the weight of material (sodium chloride)
we had to supplement distilled water to 100 mm nothing
more to add 25 mm Since the solution became 76 mm we add
automatic 24 mm only bringing to our simple solution size of
100 mm and with this we have completed the work of a
simple solution (liquid medication) .
 References

1) IUPAC, Compendium of Chemical Terminology,

2nd ed. (the "Gold Book") (1997).
2) "Distilled Water And CPAP Usage". cpap.com.
Archived from the original on 2014-07-05
3) 123> water for pharmaceutical purposes (pdf) .
hmc . sup. Org.p.2. Retrieved 14 January 2017
4) "Pharmacopeia of the United States of America,
32nd revision, and the National Formulary, 27th
edition," 2009, pp.1 to 12.