5/14/2016

1. It is the only unicyclic Antidepressant:

a. Lexapro -escitalopram
RATIONALIZATION b. Prozac - fluoxetine
c. Wellbutrin - bupropion
Module 1 d. Remeron – mirtazapine
(Organic Chem, Inorganic Chem, Medicinal Chem)
Jerico Isaiah S. Dumbrique, RPh

Thenard’s blue
Reaction from:
Aluminum heated in Sodium carbonate
in Cobalt nitrate soln
2. The ion that gives positive result to Thenard’s 3. A fourth generation Cephalosporin:
Test causes: a. Axera – cefepime
a. Reye’s syndrome - b. Rocephin – ceftriaxone
b. Minamata diseases - c. Zinacef – cefuroxime
c. Wilson’s disease - d. Monowel – cefoxitin
d. Shaver’s disease -

4. A rule that states that when stress is applied 5. This element is present in Insulin:
to a system in equilibrium, the equilibrium a. Co
shifts to relieve stress: b. Zn
a. Law of Conservation of Mass c. Mg
b. Law of Definite Proportion d. Fe
c. Law of Mass Action e. NOTA
d. Le Chatelier’s Principle

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6. It is administered in an ice-cold condition to 7. The ion that gives a purple solution with
lessen its disagreeable bitter taste; Sodium bismuthate:
parenterally used as an anti convulsant: a. Cobalt
a. Glauber’s salt b. Ferrous
b. Rochelle salt c. Manganese
c. Epsom salt d. Ferric
d. Purgative lemonade

Q#49
9. Principle which states that it is impossible to
8. The sum of the number of protons & neutron: accurately determine simultaneously the
a. Mass number position & motion of an electron:
b. Atomic weight - average mass of atoms of an a. Pauli’s exclusion principle The Aufbau (building up)
Principle:
element b. Aufbau principle an orbital cannot take more
c. Isotope - atoms of the same element can c. Heisenberg principle than 2 electrons.
have different numbers of neutrons d. NOTA
d. Atomic number - # of protons present in
nucleus

10. Acids have the following properties except: 11. Which of the ff is/are
considered slow
a. pH below 7
acetylators: a. III only
b. acceptor of protons I. Eskimos b. I and II only
c. neutralizes base II. Egyptians c. III and IV only
d. Sour taste III. Filipinos d. II and IV only
IV. Mediterranean Jews e. I and III only

Eskimos and Orientals are

rapid acetylators

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12. Which of the ff is/are 13. An agent that prevents infection by the
parent drug/s? destruction of pathogenic microorganisms
a. I and II only when applied to inanimate objects:
I. Digitoxin b. III and IV only a. Antiseptic
II. Hydrocortisone c. I, II and IV only
b. Disinfectant
III. Primidone d. I, III, and IV only
c. Antibiotic
IV. Propranolol e. AOTA
d. Sanitizer
e. Pesticide

14. A dye used as an antidote for cyanide 15. The antibiotic that binds with Ribosome 30s
poisoning: It promotes conversion of subunit:
a. Malachite green hemoglobin to a. Chloramphenicol
methemoglobin, which
b. Methylene blue b. Tetracycline
because of its high affinity for
c. Phenolphthalein cyanide ion diverts it from c. Erythromycin
d. Gentian violet inactivating Cytochrome C d. Lincomycin
e. NOTA e. Penicillin
30S
A-minoglycosides
T-etracycline

16. Structure of the penicillin molecule shows it 17. Tienam is a

to contain a fused ring system which is the: combination of:
a. β – lactam thiazolidine structure a. II and IV
b. β – lactam penam structure I. Piperacillin b. I and II
c. 6 – Aminopenicillinanic acid II. Cilastatin c. I and IV
d. β – lactam phenylpenicillin ring III. Tazobactam d. II and III
e. β – lactam alkylamino ethyl ring
IV. Imipenem e. I and III

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18. Vigocid is a 19. The 1st aminoglycoside antibiotic to be used

combination of:
in chemotherapy:
a. II and IV a. Amikacin
I. Piperacillin b. I and II
II. Cilastatin b. Gentamicin
c. I and IV
III. Tazobactam c. Streptomycin
d. II and III
IV. Imipenem e. I and III d. Kanamycin
e. Neomycin

20. It is used primarily for treating polycythemia 21. Diamox is:

vera: a. Methazolamide
a. Hexamethylamine b. Dichlorphenamide
b. Asparaginase c. Amoxicillin
c. Tamoxifen d. Hydrochlorothiazide
d. Pipobroman e. Acetazolamide
e. Hydroxyurea

Q#91(same)
22. The major adverse effect of Midamor: 23. The major source of histamine in the body
a. Hypokalemia results from the decarboxylation of this amino
b. Hyponatremia acid:
c. Hypocalcemia a. Tryptophan Serotonin
d. Hyperkalemia b. Histidine
e. Hypomagnesemia c. Tyrosine Dopa-->NE/Epi
d. Phenylalanine
e. Arginine

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24. A class of antibiotics that contain a 25. Which of the following

macrocyclic ring bridged across two is/are side effect/s of
nonadjacent positions of an aromatic nucleus dactinomycin? a. I, II and III
and called ansamycins:
b. I and II
a. Cephalosporins I. Alopecia c. II and III
b. Macrolides II. Bone marrow d. I only
c. Penicillins depression
d. Rifamycins e. III only
III. Nausea and vomiting
e. Aminoglycosides

26. A semi-synthetic derivative of 27. Which of the following

podophyllotoxin which in combination with is/are brand name/s of
other chemotherapeutic agents is the first Ibuprofen: a. I only
choice treatment for small-cell lung cancer:
b. II only
a. Vinblastine I. Tylenol c. I and II only
b. Vincristine II. Advil d. AOTA
c. Doxorubicin Effective alone or in combination III. Siverol
d. Daunorubicin w/ other agents for refractory e. I and III
e. Etoposide testicular tumors, acute
nonlymphocytic leukemia,
Hodgkin’s dse, Non Hodgkin’s
lymphoma, Kaposi’s sarcoma

28. Possesses the antitussive properties of 29. This is entitled when a neutron converts to a
codeine, without the analgesic, additive, proton:
central depressant, and constipating features: a. Positron
a. Levopropoxyphene b. Negatron
b. Noscapine c. Gamma rays
10 mg dextro = 15mg
c. Dextromethorphan dose of codeine in d. Alpha rays
d. Caramiphen antitussive effect
e. Benzonatate

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30. This describes the relative position of an 31. This is a chronic condition resembling
energy level with respect to the other energy tuberculosis in symptom:
levels present: a. Silicosis
It develops after long exposure (7
a. Principle quantum number yrs or more) to respirable dust
b. Parakeratosis (Silica particles)
b. Magnetic spin quantum number
c. Itai-Itai disease
c. Subquantum number (l)
d. Magnetic quantum number (m l) d. Minamata disease

B. Is the magnetic component contributed by the spin of the electrons

C. l describes the different electron distribution for a given n
D. The magnetic contribution of angular momentum due to movement
of electron in space.

Q#54 Q#97
32. Same molecular formula but different order 33. Cobalt meta-aluminate is: Rinman’s green
of atomic linkages aka “Cobalt green”
a. Rinman’s green
Reaction from:
a. Functional isomer b. Azure crystals Zinc + cobalt nitrate
b. Constitutional isomer c. Thenard’s blue
Thenard’s blue
c. Enantiomers d. Emerald blue crystals aka “Cobalt blue”
d. Diastereomers Reaction from:
Aluminum heated in
Sodium carbonate in
Cobalt nitrate soln.

34. This metals exhibit autocomplexation: 35. Among the acids of halogens, which is
a. Noble metals considered to be the most acidic?
b. Volatile metals Group II-B ( Zinc, a. HBr
c. Coinage metals Cadmium and Mercury) b. HI
d. Alkaline earth metals c. HF (decreasing acidity)
d. HCl

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36. An alloy composed of 50% tin and 50% lead: 37. Vleminckx’s solution is prepared by boiling
a. Pewter sublimed sulphur and:
b. Solder Pewter: a. Lime
80% Tin & 20% Lead
c. Gun metal b. a&d
Gun Metal:
d. Rose metal 10% Tin & 90% Copper c. calcium Carbonate
Rose Metal: d. Calcium oxide
25% Tin, 25% Lead & 50%
Bismuth

3x to lumabas sa boards ko!

38. Type of sulphur used in Vleminckx’s solution: 39. Which of the following has the highest
a. Precipitated sulphur boiling point:
more carbon-carbon linkages, the
b. Lac sulphur a. Decane more bonds to break, the higher
c. Sublimed sulphur b. Pentane the boiling point.

d. NOTA c. Hexane
d. Butane

40. “Speed” is a ____________ form of 41. Potassium added in glass:

Amphetamine: a. Increases the refractive index of the glass
a. Formylated b. Makes the glass amber and light resistant
b. Acetylated c. Reduces the coefficient of expansion
c. Butylated d. AOTA
d. Methylated

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42. Produces a bluish green flame through a 43. To prepare White Lotion USP, sulfurated
cobalt glass: potash is added to:
a. Sodium Through cobalt glass: a. Zinc sulfide
b. Barium
Barium – bluish green b. Zinc oxide
Sodium – Nil(pale green)
c. Strontium c. Zinc sulfate
Potassium – crimson
d. Calcium Calcium – light green d. NOTA
Strontium – purple

Q#45
44. It is a measure of the energy required to 45. It is the ability of an atom in a molecule to
remove an electron by overcoming the attract electrons in itself:
Measures how strongly the atom
attractive forces of the nucleus: a. Electron affinity attracts ADDITIONAL electrons
a. Electron affinity b. Electronegativity
Measures how strongly the
b. Electronegativity c. Ionization potential atom holds to its electrons
c. Ionization potential d. NOTA
d. NOTA

46. Purest native form of uncombined carbon: 47. The unit of radiation damage used in
a. Diamond medicine:
b. Graphite a. Rem
c. Lamp black b. RBE Relative Biological Effectiveness of the radiation
d. Coal c. Sievert SI unit for effective dosage; 1 sv=100 rem
d. Rad

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48. Employed as systemic acidifier: 49. It states that no two electrons in an atom
a. Sodium bicarbonate can have the same set of four quantum
b. Ammonium chloride numbers:
c. Calcium chloride a. Heisenberg uncertainty principle
d. b and c b. Aufbau principle
c. Pauli’s exclusion principle
d. a and b

50. The process by which water molecules move 51. Give the IUPAC name of the given chemical
under high pressure through a semipermeable CH2=CHCH2CH2CH3:
membrane from the more concentrated to the a. Pentene
less concentrated solution: b. 1- pentene
Lower to higher concentration c. Pentane
a. Osmosis
d. 1- pentyne
b. Passive diffusion
e. 2- pentene
c. Active diffusion
•
d. Reverse osmosis

52. The chemical CH3OCH3 is an example of 53. The compound with the formula,
what type of organic compound: CH3CH2COCH2CH3 is a/an:
a. Ketone •Ether: R-O-R a. Ketone
•Alcohol: ROH
b. Ester •Aldehyde: RCHO
b. Aldehyde
c. Ether •Ketone: RCOR c. Carboxylic acid
d. Aldehyde •Carboxylic acid: RCOOH d. Ether
•Ester: RCOOR
e. Acid anhydride •Acid halide: RCOX e. Ester
•Amide: RCONH2

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54. Stereoisomers that are not mirror-images of 55. What is the most potent effect of
each other are called: trimethylxanthine substitutions in positions
a. Structural isomers 1,3, and 7 of the xanthine molecule:
b. Cis-Trans isomers a. Diuresis
c. Enantiomers Mirror-image isomers that are b. Coronary Vasodilation
not super imposable
d. Anomers c. Cardiac stimulation
e. Diastereomers d. CNS stimulation
e. Skeletal muscle relaxation

56. The structure given below represents the 57. What is the IUPAC name of Valproic acid:
common structure of which group of drugs: a. 2- Methylpropanoic acid
b. 2- Ethylbutanoic acid
a. Benzodiazepine c. 2- Propylpentanoic acid
b. Barbiturates d. 2- Butylhexanoic acid
c. Phenothiazine e. 2- Pentylheptanoic acid
d. SSRIs
e. MAOIs

58. Which of the following drug is also known as 59. Which of the following calcium channel
1,3-dimethylxanthine: blockers is a benzothiazepine:
a. Theophylline a. Verapamil - phenylalkylamine
b. Caffeine 1,3,7-trimethylxanthine b. Nifedipine - dihydropyridine
c. Theobromine 3,7-dimethylxanthine c. Diltiazem
d. Pentoxyfylline 1-(5-oxohexyl)-3, 7-dimethylxanthine d. Amlodipine - dihydropyridine
e. Doxofylline 7-(1,3-dioxolan-2-ylmethyl)-1,3- e. Isradipine - dihydropyridine
dimethylpurine-2,6-dione

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60. Which of the following 61. Which of the following agents is an example
endogenous substances of an H2-antihistamine:
promote platelet a. I only a. Telfast -fexofenadine
agrregration:
b. III only b. Pariet - rabeprazole
c. I and II only c. Prevacid – lansoprazole
I. cAmp Inhibits!
d. II and III only d. Aerius -desloratadine
II. TXA2
e. AOTA e. Ulcin - ranitidine
III. ADP

62. Which of the following drug is an example of 63. Which of the following opioids contains a
Proton Pump Inhibitor: piperidine nucleus: •Phenanthrene:
a. Pariet - rabeprazole a. Dextromethorphan Codeine
Oxycodone
b. Ulcin - ranitidine b. Oxycodone Oxymorphone
c. Iselpin - sucralfate c. Pentazocine Hydromorphoine
d. Zantac - ranitidine d. Meperidine •Miperidine:
Diphenoxylate
e. Telfast - fexofenadine e. Codeine Fentanyl
•Benzomorphan:
Pentazocine

64. A given drug is known to antagonize the 5- 65. Which of the following agents is primarily a
HT 1D receptor. What is most likely clinical 5-HT3 receptor antagonist:
indication of this drug: a. Ondansetron
a. Glaucoma b. Cisapride
b. Migraine c. Clozapine
c. Hypertyension d. Ergonovine
d. Anxiety e. Naratriptan
e. Psychosis

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66. This form of insulin is the primary storage 67. Which of the following
form in man: is/are factors affecting
Form of Insulin that is absorbed drug metabolism: a. I only
a. Monomer and interacts with insulin receptor
b. Dimer b. AOTA
I. Age c. I and II only
c. Tetramer
II. Economic status d. I, III and IV only
d. Pentamer
III. Species and strain e. I, II and III only
e. Hexamer
IV. Gender

68. The term that denotes the selective 69. Phenol coefficient is defined as the ratio of a
metabolism of two or more similar functional disinfectant to the dilution of phenol required to
groups, or two or more similar atoms that are kill a given strain of a bacterium. What
positioned in different regions of a molecule: microorganism is used in determining the phenol
a. Stereoisomerism coefficient?
a. Bacillus subtilis
b. Regioselectivity
b. Enterobacter aerogenes
c. Selective toxicity
c. Pseudomonas aeruginosa
d. Substrate stereoselectivity
d. Salmonella typhi
e. Bioselectivity e. Proteus vulgaris

70. A preparation of 5% iodine in water with 71. Methicillin is chemically named as:
potassium iodide: •Iodine Solution: a. 2-Ethoxy-1-naphthylpenicillin
a. Iodine solution 2% Iodine in Water with b. 5-Methyl-3-phenyl-4-isoxazolylpenicillin
Sodium Iodide
b. Iodine tincture •Iodine Tincture: c. 5-Methyl-3-(2,6-dichlorophenyl)-4-isoxazolyl-
c. Lugol’s solution 2% Iodine in 50% alcohol penicillin
d. Mayer’s reagent with Sodium Iodide d. 2,6-Dimethoxylphenylpenicillin
•Mayer’s reagent:
e. Wagner’s reagent Potassium Mercuric Iodide e. 2,6-Dimethylpenicillin
•Wagner’s reagent:
Iodine in Potassium Iodide.

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72. A group of antibiotics that are derivatives of 73. Drowsiness is a side effect of antihistamines
an octahydronaphthacene,a hydrocarbon that is common to the:
system that comprises four annelated six- a. Ethylenediamines Ex. aminophylline
membered rings:
b. Tertiary aminoalkyl ethers
a. Macrolides Mostly
c. Phenothiazine
b. Tetracycline antipsychotics
c. Lincomycins d. H2-receptor antagonists
d. Polymyxin e. Cimetidine
e. Sulfonamides

74. It has become the drug of choice in the 75. A depolarizing neuromuscular blocking agent
treatment of genital herpes: that causes spastic paralysis to susceptible
a. Symmetrel - amantadine helminthes:
b. Zovirax -acyclovir Also used in HSV1 & 2, a. Pyrantel pamoate
Varicella-Zoster, Inh. fumarate reductase helminth
c. Hepsera -adefovir Epstein Barr
b. Thiabendazole specific
d. Tamiflu -oseltamivir c. Mebendazole Irreversibly block glucose uptake
e. Valtrex -valaciclovir d. Niridazole
e. Niclosamide

76. A non steroidal agent that has shown potent 77. An ion that often shows expectorant action
antiestrogenic properties in animals and is is:
useful in the palliative treatment of advanced a. Iodide
breast cancer in postmenopausal women:
b. Phosphate
a. Megestrol
c. Fluoride
b. Testolactone
c. Mitotane d. Iodate
d. Leuprolide
e. Tamoxifen

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78. Copper is an essential trace element used for 79. The only single acid that can dissolve gold:
the utilization of iron occurs in: a. HCl
HCl and HNO3 can’t
a. Hemoglobin b. HNO3
dissolve gold alone
b. Albumin c. Selenic acid but when mixed as
c. Hemocyanin Respiratory aqua regia (3:1) it can
d. Aqua regia
pigment
d. Heme dissolve gold but not
•Hemoglobin contains Iron in its molecule as SINGLE acid.
•Heme constitutes about 4% of its weight
consisting iron in the center of pyrrole-
porphyrin ring
•Albumin is the primary protein found in
blood

80. Reduction occurs in: 81. Argyria can be caused by:

GEROA
a. Cathode LEORA a. Gold
b. Anode b. Cobalt
c. Both Cathode – c. Iron
negatively charged
d. None of these electrode d. Silver

Anode – positively
charged electrode

82. A member of the second triad of Group VIII: 83. BAL is:
Used in treating heavy
a. Platinum a. British Anti- Lewisite metal poisoning such as
b. Rhodium With Ruthenium and b. 2,3 dimercaptopropranolol mercury and gold.
Palladium
c. Nickel c. 3,2 dimercaptopropranolol
d. Iridium d. a and b

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84. Soft coal is: 85. The first element to be discovered by the use
a. Anthracite of spectroscope:
It contains 70% of Carbon +
b. Bituminous a. Rubidium
large amt of volatile matters
c. Charcoal b. Cesium
d. Activated charcoal c. Iridium
d. Uranium

86. Inadequate oxygen tension in air i.e. Baguio, 87. Mercury that falls into cracks and other
high altitude: difficult to clean places is removed best by
a. Histotoxic covering with: It forms sulfide with mercury and is
b. Anemic a. Sulfur then easily vacuumed to remove
easily.
c. Anoxic b. Sodium hydroxide
d. Stagnant c. Potassium dichromate
d. Zinc oxide

88. Fuller’s earth is: 89. Pink in appearance:

a. Hydrated aluminium magnesium trisilicate a. Copper
b. Floridin b. Nickel green
c. Aluminium magnesium trisilicate c. Cobalt (II)
d. b and c d. a and c

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M
E
T
A
90. In given period, as the atomic number L 91. The major source of histamine in the body
increases, metallic properties: L results from the decarboxylation of this amino
I
a. Increase C acid:
b. Decrease a. Tryptophan
P
c. Remain the same b. Histidine
R
d. Double O c. Tyrosine
P d. Phenylalanine
In e. Arginine
Metallic property decreases crease

92. Grignard reagents usually contain: 93. Standard temperature for gas:
a. Co a. 0⁰ C
b. Cu Grignard reagents are R-Mg-X b. 314K
c. Fe compounds that are used as c. 273K
intermediates in synthesis
d. Mg d. a and c

94. What is the functional group for ketones: 95. The ion that gives a Turnbull’s blue
a. Carboxyl group precipitate with potassium ferricyanide:
b. Hydroxyl group •Carboxyl group for Caboxylic acids a. Ferrous
•Hydroxyl group for alcohols
c. Amino group •Amino group for Amines b. Ferric Ferrous ferricyanide
d. Carbonyl group c. Cobalt
d. Nickel

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96. The ion that gives a Prussian blue precipitate 97. The ion that gives positive result to Rinman’s
with potassium ferrocyanide: green:
a. Ferrous •Fe7(CN)18⋅14H2O Ferric a. Aluminum aka “Cobalt green”
b. Ferric ferrocyanide b. Chromium
•aka Berlin Blue or Parisian Reaction from:
c. Cobalt blue c. Manganese
Zinc + cobalt nitrate
d. Nickel •It was the traditional “blue” d. Zinc
in blueprints
•It has been used as
antidotes for certain heavy
metal poisoning

98. The first element produced artificially is: 99. Which of the following is a thiazolidinedione:
a. Rn a. Actos -pioglitazone
b. Ta b. Glucophage -metformin Metformin – Biguanide
c. Tc c. Solosa - glimepiride Glimepiride- Sulfonyureas
d. Pt d. Glucobay – acarbose

100. All are classified as 2nd generation

sulfonylureas except:
1st gen:
a. Gliclazide •Chlorpropamide
b. Gliburide •Acetohexamide
c. Glimepiride •Tolbutamide
•Tolazamide
d. Glipizide
2nd gen:
*all starting in GLI, GLY
except GLIMEPIRIDE

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