Professional Documents
Culture Documents
Vestigial organs
▸ Vestigial organs are physical structures that were fully developed and functional in an
ancestral group of organisms but are reduced and unused in the later species.
▸ These vestigial organs help researchers see how some modern organisms are related to
ancestors that had similar structures
Similarities in Development
▸ Scientists in the 1700s were fascinated by the fact that various animals looked similar in
their earliest stages of life.
▸ They noted that as the organisms developed, they became less and less alike. Today’s
scientists continue to compare the developmental stages of different species.
▸ The adult stages of many species do not look similar. For example, a rabbit does not
look anything like a chicken. However, study reveals that the early life stages of a
chicken and a rabbit are similar. An organism that is in an early stage of development is
called an embryo.
Cytochrome c
▸ Cytochrome c is part of the electron transport chain down which electrons are passed to
oxygen during cellular respiration.
▸ Cytochrome c is found in the mitochondria of every aerobic eukaryote — animal, plant,
and protist. The amino acid sequences of many of these have been determined, and
comparing them shows that they are related.
▸ Human cytochrome c contains 104 amino acids, and 37 of these have been found at
equivalent positions in every cytochrome c that has been sequenced.
▸ We assume that each of these molecules has descended from a precursor cytochrome
in a primitive microbe that existed over 2 billion years ago. In other words, these
molecules are homologous.
▸ The data can then be tabulated to show the number of differences. A cladogram, or
branching tree can then be made to show the relationship among the organisms
Sequencing Cytochrome c
▸ The first step in comparing cytochrome c sequences is to align them to find the
maximum number of positions that have the same amino acid.
▸ Sometimes gaps are introduced to maximize the number of identities in the alignment
(none was needed in this table).
▸ Gaps correct for insertions and deletions that occurred during the evolution of the
molecule.