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Drug Name Drug Possible Side Mechanism of Nursing

(Generic and Classification Effects Action Responsibilities in


Brand name) And Indication administering the drugs
(1 point each) (2 points each) (2 points each) (2 points each) (3points each)
atorvastatin Antilipemics Frequent: Inhibits HMG-  Assess baseline lab
calcium (HMG-CoA Headache CoA reductase, results: cholesterol,
reductase Occasional: an early (and triglycerides, and hepatic
Common brand inhibitors) myalgia, rash, rate-limiting) function tests.
name: Lipitor  Hyperlipidemia: pruritus, allergy step in  Obtain dietary history.
adjunct to diet cholesterol  Assess and monitor for
to reduce LDL, Rare: Flatulence, biosynthesis S/E.
Available brands
in Philippines: total dyspepsia,  Watch for signs of
cholesterol, depression myositis and myopathy
 Actimed
apolipoprotein (unexplained muscle pain,
Atorvastatin
B, and tenderness, weakness,
 Adivast
triglyceride malaise, dark urine,
 Atonamis
levels and to fever). Drug may be
 Ator-10/Ator- discontinued.
increase HDL
20/Ator-40
levels (40 mg in  Monitor lab values for
 Atorcad patients therapeutic response.
 Atorvast- requiring  Teach patient about
Natrapharm greater than proper dietary
 Atorwin 45% reduction management, weight
 Bestatin in LDL-C) control and exercise.
 Itorvaz Explain the importance of
 Lipitor controlling high fat levels.
 Ranvast  Tell patient to inform
 Rhea prescriber of all adverse
Atorvastatin reactions, such as muscle
 RiteMED pain, malaise, and fever.
Atorvastatin  Warn patient to avoid
 Saatin alcohol or large quantities
 Truvast of grapefruit juice.
 Xentor
 Zydusatorva
10/Zydusator
va 20
piperacillin Antibiotics Frequent: Piperacillin  Question patient for
sodium- (Extended- Diarrhea, inhibits cell wall history of allergies,
tazobactam spectrum headache, synthesis by especially to penicillin or
constipation,
sodium penicillins-beta- binding to cephalosporin.
nausea, insomnia,
lactamase bacterial cell  Use cautiously in patients
Common brand inhibitors) rash. Occasional: membranes with bleeding tendencies,
name: Zosyn  Cholecystitis Vomiting, while uremia, hypokalemia, and
bacterial dyspepsia tazobactam allergies to other drugs.
Available brands (heartburn,
infection: inactivates Monitor hematologic and
in Philippines: indigestion,
intestinal bacterial beta- coagulation parameters.
 Bizataz epigastric pain),
organisms pruritus, fever, lactamase thus  Monitor daily pattern of
 Diapiptaz 4.5
producing agitation, protecting bowel activity and stool
 Iztam-
beta- candidiasis, piperacillin consistency. Mild GI
2.25/Iztam-
lactamase, dizziness, from enzymatic effects may be tolerable,
4.5
abdominal pain,
 Pantazo which are degradation, but increasing severity
edema, anxiety,
 Perbactam resistant to extending its may indicate onset of
dyspnea, rhinitis.
 Piptaz penicillin and spectrum of antibiotic-associated
 Pipzo cefazoline, are activity, and colitis. Initiate therapeutic
 Piracil likely to be preventing measures as needed. Drug
 Plepra-T 4.5
detected, so bacterial may need to be stopped.
 Prazitam 4.5
the use of overgrowth.  If large doses are given or
 Tazobak
 Tarzocin penicillin/ β- if therapy is prolonged,
 Tarzoget lactamase bacterial superinfection
 Tarzovex inhibitors such may occur especially in
 Tazur as piperacillin- elderly, debilitated, or
 Ureitaz tazobactam is immunocompromised
 Vactazo recommended. patients. S/S include
 Vigocid
fever, vomiting, diarrhea,
 Zopip
anal/genital pruritus, and
oral mucosal changes
(ulceration, pain, and
erythema).
 If rash develops, monitor
patient closely and
discontinue if lesion
progresses.
 Monitor I&O and
urinalysis results.
 Drug contains 2.84 mEq
(65 mg) sodium per gram
of piperacillin. Monitor
patient’s renal function
tests, sodium intake and
electrolyte levels
especially K+ and Na+.
 Tell patient to report
adverse reactions
promptly.
 Tell patient to report
discomfort at the I.V. site.
metoclopramide GI stimulant ALERT: Doses of 2 Stimulates  Assess for dehydration
hydrochloride (Dopamine mg/kg or greater, motility of (poor skin turgor, dry
antagonist), or increased upper GI tract, mucous membranes, and
length of therapy,
Common brand Antiemetic increases lower longitudinal furrows in
may result in a
name: Metozolv Nausea and greater incidence
esophageal tongue). Assess for
ODT, Reglan vomiting sphincter tone, nausea, vomiting,
of side effects.
associated with Frequent: and blocks abdominal distention, and
Available brands various GI Drowsiness, dopamine bowel sounds.
in Philippines: restlessness,
disorder/disease receptors at  Monitor for S/S that may
 Clomitene fatigue, lethargy. the indicate NMS.
 Clozil Occasional:
 Gastrosil
chemoreceptor  Monitor patient for
Dizziness, anxiety,
 Mevtex headache, trigger zone. dizziness, headache, or
insomnia, Therapeutic nervousness after
breast effect: metoclopramide is
tenderness, accelerates stopped; these may
altered intestinal indicate withdrawal.
menstruation, transit and  Remind patient to avoid
constipation,
gastric tasks that require
rash, dry mouth,
and emptying, and alertness, motor skills
galactorrhea. relieves nausea until response to drug is
Rare: and vomiting. established and 2 hours
Hypotension, after doses.
hypertension, and  Urge patient to report
tachycardia.
persistent or other
Adverse Effects/ serious adverse promptly.
Toxic Reactions  Advise patient not to
Neuroleptic drink alcohol during
malignant therapy.
syndrome
(diaphoresis,
fever, unstable
BP, irregular
pulse,
arrhythmia,
muscular rigidity).

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