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A DETAILED LESSON PLAN IN SCIENCE FOR GRADE 10

Monaliza Q. Laid
BSE - Biology
December 01, 2019

I. LEARNING COMPETENCIES
At the end of a 60-minute period, the Grade 10 learners will be able to:
1. Identify the amino acids coded for by the mRNA codon using the Genetic Code Table.

SUBJECT MATTER
GENETIC CODE

A. References
Textbooks:
Science Grade 10 Learners Material, page 280 – 291
Science Grade 10 Teachers Guide, page 208 – 209

B. Materials
Visual Materials, Activity Sheets, Genetic Code Table, Scotch Tape

C. Ideas
Genetic code – correspondence between specific nucleotide sequences and amino acids.
Genetic code is the nucleotide triplets of DNA and RNA molecules that carry genetic
information in living cells.

D. Processes
Identifying

E. Values Integration
Coordination

II. PROCEDURE

TEACHER ACTIVITY LEARNER ACTIVITY


A. Preliminary Activities

Opening Prayer

May I request, Ms. Binoya to lead the prayer. (A learner leads the prayer)

Greeting

Good morning, class! Good morning, Ma’am Mona! Welcome


to Grade 10 – Juan Luna. Mabuhay!

How are you feeling today? We’re great!

Checking of Attendance
That’s good to hear. Class, your quiz for today will
serve as your attendance.

Checking of Assignment
Did I give you an assignment last meeting, class? Yes, Ma’am.
Everybody please pass your assignments in front.

Review of Past Lesson


Who can recall, what was our previous lesson last Our topic last meeting was all about
Friday? translation, Ma’am.

Very good!
And what did you learn from that lesson? I learned that translation is an assembly
of amino acid chain according to the
sequence of nucleotides in mRNA.

Very good! It seems that you have learned on our


previous lesson. Keep it up.

B. Motivation
Class, I have here two jumbled words. Can you guess Yes, ma’am.
what they are?

TICENEG DOEC Genetic Code.

Very good! You have answered it correctly.

C. Lesson Proper

1. Topic
Our topic for today will be all about genetic codde.

2. Reading of Objectives
Please kindly read our objective for today Mr. Alesna. (Learner will read the objective.)

3. Unlocking of Difficult Terms

DNA (deoxyribonucleic acid) – genetic material


consisting of a double helix of nucleotides

messenger RNA – a molecule of RNA that encodes a


protein

transfer RNA – a molecule of RNA that binds an


amino acid at one site and an mRNA codon at its
anticodon site.

4. Developmental Activity
Each learner will be given an activity sheet. On the
activity sheet, the learner will be able to read the
procedure together with the questionnaire that they will
answer.

*The activity sheet is attached at the last page.*

5. Discussion

What comes on your mind when you hear the word Genetic code is a set of rules that specify
genetic code? the codons in DNA or RNA that
corresponds to the amino acids.

Very good! Everybody read the definition of the genetic Genetic code is a set of rules that
code. contains genetic materials (DNA and
RNA) that is translated into proteins
(amino acids).
How many codons are there in this genetic code table?
24, ma’am
Nice try. Another answer?
Nice guess. But who else has another answer? 56, ma’am.
64, ma’am.
Very good! In the genetic code table, there are 64
unique codons. In relation to this, what do you think is
the number of amino acids in this genetic code table?
24, ma’am.
Nice guess. Another answer?
Nice try. Another answer? 30, ma’am.
20, ma’am.
Very good! There are only 20 amino acids in the genetic
code. How many codon/s corresponds to one amino
acid?
One only, ma’am.
Nice guess. But is it only one?
No, ma’am. There are more than one
codon for one amino acid.
Yes, ma’am.
Very good! Take for an example the amino acid valine.
There are four codons that corresponds with this amino
acid. Can you name the codons? GUU, GUC, GUA, GUG.

Very good! In completing the table in your answer


sheet, let us have a short recap on our previous lesson.
In replication what is the base – pairing?
Adenine – Thymine and vice – versa,
Very good! After the replication process is the Guanine – Cytosine, ma’am.
transcription. What is now the base – pairing?
Adenine pairs with Uracil, Thymine pairs
with Adenine. Thymine will no longer be
included in the transcription process. And
guanine pairs with cystosine (vice versa).
Very good! After transcription is the translation, right
class?
Yes, ma’am.
Can you give me the base – pairing?
Adenine – uracil (vice versa) and
Very good! Based on our previous lesson, how do we Guanine – cytosine (vice versa).
locate the amino acid?
We have to take a look at the mRNA,
Very good! So, it seems that you have understood our ma’am.
lesson.

Are there any more questions, clarifications?


None, ma’am.
Before evaluating what you learned, I have some
questions.
D. Generalization

What is a genetic code, class?


Genetic code is the set of rules that
contains genetic material that is
translated into proteins.
Very good! How many codons and amino acid are there
in the genetic code? There are 64 unique codons and 20
amino acids.

E. Application

What do you think is the importance of the genetic


code? I think the importance of genetic code is
that it provides evidence from the origin
of life of a living organism.
Very well said.

So, did you understand our lesson today?


Yes, Ma’am.
Are there any more questions or clarifications?
Yes, Ma’am.
Very well, let’s proceed to the evaluation.
None.

III. EVALUATION
Give the corresponding amino acids of the following codons given below. Use the genetic code
table.

1. UUU 6. AUG
2. CUU 7. UGA
3. AUU 8. GGA
4. GUG 9. CGG
5. UCA 10. GAG

IV. ASSIGNMENT
Research what is the difference between gene mutation and chromosomal mutation.
Name:________________ Section:____ Score:___

Activity 5

Trace the Code

Objective:

 Identify the amino acids coded for by the mRNA codon using the genetic code table.

Materials:

 Genetic code table


 Activity sheets

Procedure:

1. Fill in the table below.


2. Refer the genetic code table to identify the amino acid.

Order of bases in Order of bass in Order of bases in Amino acid coded


DNA mRNA (codon) tRNA into proteins
TAG AUC
CAT
GUC
CCA Methionine
Valine
ACU
ACA UGU
AAA
GAA CUU

3. To determine the order of bases in the first column (DNA), second column (codon), and
third column (anticodon), consider the complementary base pairs in DNA: adenine pairs
with uracil and guanine pairs with cystosine.
4. To identify the amino acid, look at the bases in the mRNA codon, e.g., AUG using the
genetic code table. Look for the first letter of the mRNA codon on the left side of the
genetic code table (A), the second letter of the mRNA on the second letter column (U),
and the third letter on the right side column (G). AUG codes for the amino acid-
methionine.
5. Do the same with the other codons in the chart.

Guide Question:

Why is specific base – pairing is essential to the processes of transcription and translation?

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