Name: ________________________ Class: ___________________ Date: __________ ID: A

CEST 2 BIOLOGY GRADE 12 2017

Multiple Choice
Identify the choice that best completes the statement or answers the question.

____ 1. If a section of DNA has 13% thymine, then there is _____ adenine.
a. 13% c. 87%
b. 37% d. 26%

____ 2. What kind of chemical bond is found between paired bases of the DNA double helix?
a. Hydrogen c. Peptide
b. Ionic d. Covalent

____ 3. A nucleotide consist of ....

a. A sugar, a phosphate, and a nitrogenous base
b. A sugar, two phosphate, and a nitrogenous base
c. A sugar, a phosphate, and two nitrogenous base
d. Two sugar, a phosphate, and nitrogenous base

____ 4. What is meant by the description "antiparallel" regarding the strands that make up DNA?
a. One strand contains only purines and the other contains only pyrimidines
b. The 5' to 3' direction of one strand runs counter to the 5' to 3' direction of the other strand
c. Base pairings create unequal spacing between the two DNA strands
d. One strand is positively charged and the other is negatively charged.

____ 5. A geneticist isolates a gene for a specific trait under study. She also isolates the corresponding mRNA. Upon
comparison, the mRNA is found to contain 1,000 fewer bases than the DNA sequence. Did the geneticist
isolate the wrong DNA?
a. yes, mRNA is made from a DNA template and should be the same length as the gene
sequence
b. yes, the mRNA should contain more bases than the DNA sequence because bases
flanking the gene are also transcribed
c. no, the final mRNA contains only exons, the introns were removed
d. no, the mRNA was partially degraded after it was transcribed

1
Name: ________________________ ID: A

____ 6. The following pedigree chart is for a family, some of whose members exhibit the dominant characteristic, W.
Affected individuals are indicated by a dark square or circle.

What is the genotype of individual II-4?

a. WW c. ww
b. Ww d. Ww or ww

____ 7. A DNA strand with the sequence AACGTAACG is transcribed. What is the sequence of the mRNA molecule
synthesized?
a. AACGTAACG c. AACGUAACG
b. UUGCAUUGC d. TTGCATTGC

____ 8.
Based on the picture above, the process that happen in no 1 is....
a. Translation, copying genetic information from DNA
b. Transcription, copying genetic information from DNA
c. Translation, translate the information from DNA
d. Replication, translate the information from DNA

2
Name: ________________________ ID: A

____ 9. What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA

a. Met-Pro-Ala-Val c. Met-Pro-Val
b. Tyr-Gly-His d. Tyr-Gly-Arg-His

____ 10. Some events that take place during the synthesis of a specific protein are listed below.
A. Messenger RNA attaches to a ribosome.
B. DNA serves as a template for RNA production.
C. Transfer RNA bonds to a specific codon.
D. Amino acids are bonded together.
E. RNA moves from the nucleus to the cytoplasm.
The correct order of these events is
a. B E A C D c. B C E D A
b. D A E C B d. C B A E D

____ 11. During which stage of mitosis does cytokinesis usually start in animals?
a. Prophase c. Metaphase
b. Prometaphase d. Telophase

____ 12. Look at the characteristics below:

- Nuclear membrane disappears,
- Spindle fibres appear,
- The chromosomes visible
The characteristics above are all observed in _______ .
a. Prophase c. Anaphase
b. Metaphase d. Telophase

____ 13. A diploid cell with 44 chromosomes divides 3 times by mitosis. What will be number of formed cells and
their chromosomes number?
a. 2 & 44 c. 4 & 22
b. 8 & 44 d. 8 & 22

3
Name: ________________________ ID: A

____ 14. During which stage of meiosis do tetrads line up at the equator?
a. Metaphase I c. Telophase I
b. Metaphase II d. Anaphase II

____ 15. Look at the picture below.

This cell is in which phase of meiosis?

a. Metaphase I c. Anaphase I
b. Metaphase II d. Anaphase II

____ 16. If the DNA content of a diploid cell in the G1 phase of the cell cycle is x, then the DNA content of the same
cell at metaphase of meiosis I would be......
a. 0,25 x c. x
b. 0,5 x d. 2x

____ 17. In which process meiosis takes place?

a. Repair of a wound in multicellular organism
b. Asexual reproduction in multicellular organism
c. Production of gametes
d. Growth of baby in mother’s womb

____ 18. The genotype of a pea plant can best be determined by:
a. Analyzing its genes c. Crossing it with a recessive plant
b. Looking at it d. Eating it

____ 19. Black fur on wolves is determined by dominant B allele and white fur on wolves is determined by recessive b
allele. What is the phenotypic ratio if heterozygous black fur wolf crossed with white fur wolf?
a. Black : white = 1 : 1 c. Black : grey : white = 1 : 2 : 1
b. White : Black = 1 : 3 d. Grey : white = 1 : 1

____ 20. In dihybrid crosses, the ratio 9:3:3:1 indicates ___.

a. Codominance c. Incomplete dominance
b. Independent assortment d. Three alleles for each trait

____ 21. Black fur on rabbit is determined by dominant B and white fur on rabbit is determined by recessives b alleles.
Whereas the long tail is determined by dominant L and short tail is determined by recessive l. If a black -
long tail heterozygous rabbit crossed with a white – short tail rabbit. The percentage for white – long tail
rabbit is?
a. 100% c. 50%
b. 75% d. 25%

4
Name: ________________________ ID: A

____ 22. In wheat plant, black (B) is epistasis to yellow (Y). bbyy is white. If black – skinned wheat (BByy) is crossed
to the yellow one (bbYY), the proportion of yellow – skinned wheat in F2 is….
a. 9/16 c. 4/16
b. 3/16 d. 1/16

____ 23. Two pairs of genes affect comb type in chickens. When both genes are recessive, a chicken has a single
comb. A dominant allele of one gene, P, gives rise to a pea comb. A dominant allele of the other (R) gives
rise to a rose comb. A gene interaction occurs when a chicken has at least one of both dominants, P___R___
which gives rise to a walnut comb. If walnut comb chicken (PPRr) is crossed with heterozygous rose comb
chicken . The probability of the offspring to have the same phenotype with the parents is...
a. 100% c. 50%
b. 25% d. 75%

____ 24. In Linaria maroccana plant : Gene A = responsible for antocyanin (a pigment which gives colors purple or
red to flowers) is dominant to gene a= no antocyanin (meaning white flower color), Gene B = react with base
(purple) dominant to gene b = react with acid (red)
Purple colored flower (AABb) is crossed with red flower (Aabb). What would be the phenotypic ratio?
a. purple : red = 1 : 1 c. purple : red : white = 9 : 3 : 4
b. purple : red : white = 4 : 2 : 2 d. purple : white = 9 : 7

____ 25. Four oclock flowers may be red, pink, or white. A cross between a red-flowered plant and a
white-flowered plant yields all-pink offspring. In the F2 generation of the above cross, which of the following
phenotypic ratios would be expected?
a. 1 : 1 : 1 c. 2 : 1 : 2
b. 1 : 2 : 1 d. 3 : 1

____ 26. In the common daisy the genes A and a, B and b represent two pairs of alleles acting on flower color. A and
B are both required for color. What will be te ratio of plants with colored flowers in the F2 of a cross
between two colorless plants, one homozygous for A and the other homozygous for B?
a. 1/16 c. 7/16
b. 3/16 d. 9/16

____ 27. What is the anti-sense sequence for the DNA sequences :TAC ACA CGG AGG GTA CGC?
a. ATACACACGGAGGGTACGC c. AUGUGUGCCUCCCAUGCG
b. ATGTGTGCCTCCCATGCG d. CGCATGGGAGGCACACAT

5
Name: ________________________ ID: A

____ 28. Which of the following cells is in anaphase of mitosis?

a. c.

b. d.

____ 29. Two true-breeding pea plants are crossed. One parent has red, axial flowers and the other has white,terminal
flowers; all F1 individuals have red, axial flowers. If 2 F1 plants are crossed, what will be the ratio of red,
terminal flowers individuals in F2?
a. 16/16 c. 3/16
b. 9/16 d. 1/16

____ 30. A plant with the genotype of AAbbCc is ____.

a. homozygous at two loci c. recessive at three loci
b. heterozygous at two loci d. triploid

____ 31. Four genes (A,B,C and D) are on the same chromosome.
Their crossing-over (recombination) frequencies are A-B: 8%, B-C: 17%, A-C: 9%, A-D: 13% and C-D: 4%.
What is the correct sequence of these genes?
a. ABCD c. BDAC
b. BACD d. BADC

____ 32. In pea plants, purple flower color (P) is dominant to white flower color (p), and smooth seed (R) is
dominant to wrinkled seed (r). Flower color and seed shape are inherited independently.
Which of the following pairs can be the parents of offspring with 3:1, puple flower-smooth seed :
puple flower-wrinkled seed phenotypic ratio?
a. PPRr X ppRr c. PpRr X ppRr
b. PpRr X PpRr d. PPRR X ppRr

____ 33. Which of the following is not a property of mRNA?

a. It has uracil nucleotides c. It includes deoxyribose sugar.
b. It is synthesized from DNA. d. It is single-stranded.

____ 34. What called a condition in which two alleles are not dominant to each other and in heterozygous
organisms both alleles are fully expressed in the phenotype (for example, human blood type alleles A
and B)?
a. incomplete dominance c. epistasis
b. co-dominance d. pleiotropy

6
Name: ________________________ ID: A

____ 35. A couple have two daughters and then three sons. They are expecting another child.
What is the chance of this child being a boy?
a. 0 % c. 75%
b. 50% d. 25%
____ 36. A woman with hemophilia (a recessive, X-linked disease) has a healthy daughter.This daughter marries a
man with hemophilia.
What is the probability that their son will be healthy?
a. 100% c. 25%
b. 0% d. 50%

____ 37. Albinism is not a sex-linked condition. It is inherited as a recessive allele.

A normally pigmented man marries an albino woman.
They have three children, one of whom is an albino.
What is the genotype of the father?
a. homozygous dominant c. homozygous recessive
b. heterozygous d. can not be concluded

____ 38. A man with blood type A marries a woman with blood type B.
What is/are the possible blood type/s for their children?
a. A, B, Ab and O c. AB, A and B
b. AB only d. A and B

____ 39. In rabbits, the allele for dark fur, R, is dominant to the allele for white fur, r.
The diagram shows a cross between a rabbit with dark fur and a rabbit with white fur.

What are the genotypes of the offspring?

a. Rr and rr c. RR and Rr
b. RR and rr d. R and r

____ 40. Which of the following is an example of polygenic inheritance?

a. pink flowers in snapdragons c. white and purple flower color in peas
b. the ABO blood group in humans d. skin pigmentation in humans

7
 ID: A

CEST 2 BIOLOGY GRADE 12 2017

Answer Section

MULTIPLE CHOICE

1. ANS: A PTS: 1 DIF: Easy

OBJ: Student can explain the structure and function of DNA TOP: Genetic Substances
2. ANS: A PTS: 1 DIF: Easy
OBJ: Student can explain the structure and function of DNA TOP: Genetic Substances
3. ANS: A PTS: 1 DIF: Easy
OBJ: Student can explain the structure and function of DNA and RNA
TOP: Genetic substances
4. ANS: B PTS: 1 DIF: Easy
OBJ: Student can explain the structure and function of DNA TOP: Genetic Substances
5. ANS: C PTS: 1 DIF: Medium
OBJ: Student can understand the central dogma of biology TOP: Protein synthesis
6. ANS: B PTS: 1
7. ANS: B PTS: 1 DIF: Easy
OBJ: Student understand the transcription process TOP: Protein synthesis
8. ANS: B PTS: 1 DIF: Medium
OBJ: Student understand the steps in protein synthesis TOP: Protein synthesis
9. ANS: C PTS: 1 DIF: Easy
OBJ: Students understand the translation process TOP: Protein synthesis
10. ANS: A PTS: 1 DIF: Easy
OBJ: Student understand the steps in protein synthesis TOP: Protein synthesis
11. ANS: D PTS: 1 DIF: Easy
OBJ: Student can explain the stages of Mitosis TOP: Cell division
12. ANS: A PTS: 1 DIF: Easy
OBJ: Student can explain the stages of Mitosis TOP: Cell division
13. ANS: B PTS: 1 DIF: Medium
OBJ: Student can explain the stages of Mitosis
14. ANS: A PTS: 1 DIF: Easy
OBJ: Student can explain the stages of Meosis TOP: Cell division
15. ANS: B PTS: 1 DIF: Medium
OBJ: Student can explain the stages of Meosis TOP: Cell division
16. ANS: D PTS: 1 DIF: Medium
OBJ: Student can explain the stages of Meosis TOP: Cell division
17. ANS: C PTS: 1 DIF: Easy
OBJ: Student can understand the role of meiosis TOP: Cell division
18. ANS: C PTS: 1 DIF: Medium
OBJ: Student understand the Mendel's law TOP: Mendell's law
19. ANS: A PTS: 1 DIF: Easy
OBJ: Student can use genetic diagrams to solve problems involving monohybrid
TOP: Mendell's Law
20. ANS: B PTS: 1 DIF: Easy
OBJ: Student understand the Mendel's law TOP: Mendell's Law

1
 ID: A

21. ANS: D PTS: 1 DIF: Easy

OBJ: Student can use genetic diagrams to solve problems involving dihybrid crossing
TOP: Mendell's Law
22. ANS: B PTS: 1 DIF: Medium
OBJ: Student can use genetic diagrams to solve problems involving extended mendellian genetics
TOP: Extended Mendellian Genetic
23. ANS: D PTS: 1 DIF: Medium
OBJ: Student can use genetic diagrams to solve problems involving extended mendellian genetics
TOP: Extended Mendellian Genetic
24. ANS: A PTS: 1 DIF: Medium
OBJ: Student can use genetic diagrams to solve problems involving extended mendellian genetics
TOP: Extended Mendellian Genetic
25. ANS: B PTS: 1 DIF: Easy
OBJ: Student can use genetic diagrams to solve problems involving extended mendellian genetics
TOP: Extended Mendellian Genetic
26. ANS: D PTS: 1 DIF: Medium
OBJ: Student can use genetic diagrams to solve problems involving extended mendellian genetics
TOP: Extended Mendellian Genetic
27. ANS: B PTS: 1
28. ANS: C PTS: 1
29. ANS: C PTS: 1
30. ANS: A PTS: 1
31. ANS: B PTS: 1
32. ANS: A PTS: 1
33. ANS: C PTS: 1
34. ANS: B PTS: 1
35. ANS: B PTS: 1
36. ANS: D PTS: 1
37. ANS: B PTS: 1
38. ANS: A PTS: 1
39. ANS: A PTS: 1
40. ANS: D PTS: 1