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Modifiable: Non Modifiable:

 Use of cocaine  History of Pre-eclampsia


 Use of cigarette  History of abdominal trauma
 Diet high in cholesterol,  Premature rupture of
saturated fat, and sodium membrane
intake  History of abruption placenta
 Short umbilical chord

Endothelial
damage

Vasoconstriction

Elevated Blood Pre-Eclampsia


Pressure (BP= 158/87 mmHg)

Platelet cluster at the site of


endothelial damage

Increased peripheral
resistance

Blood supply was reduced

Decreased Renal Decreased Placental


Perfusion Perfusion

Bleeding in Decidua
Endothelial Activation of Renin- Basalis
damage to Angiotensin-
glomerular Aldosterone System
capillary (RAAS) Formation of Hematoma

intermittent
Protein leaks Pre-Eclampsia lower Further separation of the
across capillary (BP= 158/87 abdominal placenta from the
membrane mmHg) discomfort uterine wall

Abruptio Placenta
Proteinuria At risks for acute
and chronic
uteroplacental
insufficiency Partial Separation Total Separation

Brain ischemia causes


the later emergence of Marginal Partial Complete
convulsions Abruption Abruption Abruption

Eclampsia (occurrence Vaginal Concealed Massive vaginal


of seizures and can Bleeding Bleeding bleeding or
cause coma) Concealed Bleeding

Maternal and
Fetal Death

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