Drug Data Indication/ Mechanism of Action Adverse Effects Nursing Responsibilities

Contraindication

Brand Name: Indication: Isosorbide mononitrate is a long- CNS: Headache,  Monitor cardiac
- Imdur tablets acting metabolite of the coronary agitation, anxiety, status, frequency
Prevention of angina. Not vasodilator isosorbide dinitrate. It confusion and severity of
Generic Name: indicated for acute decreases preload as measured by CV: Aggravation of angina, and BP.
- Isosorbide attacks. pulmonary capillary wedge angina, abnormal  Assess for and
mononitrate pressure (PCWP), and left heart sounds, report possible
ventricular end volume and murmurs, MI, S&S of toxicity,
Route: Contraindication: diastolic pressure (LVEDV), with a transient including
- Oral Hypersensitivity to consequent reduction in hypotension orthostatic
Dosage: nitrates; severe anemia; myocardial oxygen consumption. Hematologic: hypotension,
- 60mg closed-angle glaucoma, Hypochromic syncope,
Frequency: postural hypotension, anemia, purpura, dizziness,
- Daily head trauma, cerebral thrombocytopeni palpitations, and
hemorrhage (increases a severe headache.
intracranial pressure). Respiratory:  Lab tests:
Bronchitis, Monitor serum
pneumonia, upper electrolytes
respiratory tract periodically.
infection, nasal
congestion, Family education
bronchospasm,
coughing  Maintain correct
GI: Nausea, dosing interval
vomiting, dry with twice daily
mouth, abdominal dosing.
pain, constipation,  Note: Geriatric
diarrhea, patients are more
 susceptible to the
possibility of
developing
postural
hypotension.
 Do not withdraw
drug abruptly;
doing so may
precipitate acute
angina.

http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/I050.html