Datex-Ohmeda Centiva-5 - User Manual

Centiva/5
User’s Reference Manual

Software Revision 2.n
User Responsibility
This Product will perform in conformity with the description thereof

contained in this operating manual and accompanying labels and/or
inserts, when assembled, operated, maintained and repaired in
accordance with the instructions provided. This Product must be
checked periodically. A defective Product should not be used. Parts
that are broken, missing, plainly worn, distorted or contaminated
should be replaced immediately. Should repair or replacement become
necessary, Datex-Ohmeda recommends that a telephonic or written
request for service advice be made to the nearest Datex-Ohmeda Field
Service Support center. This Product or any of its parts should not be
repaired other than in accordance with written instructions provided by
Datex-Ohmeda and by Datex-Ohmeda trained personnel. The Product
must not be altered. The user of this Product shall have the sole
responsibility for any malfunction which results from improper use,
faulty maintenance, improper repair, damage or alteration by anyone
other than Datex-Ohmeda.
CAUTION U.S. Federal laws restrict this device to sale by or on the order of a
licensed medical practitioner. Outside the U.S.A. check local laws for
any restriction that may apply.
Datex-Ohmeda products have unit serial numbers with coded logic

which indicates a product group, the year of manufacture and a
sequential unit number for identification.
AAA B 12345
This alpha character indicates the year of product

manufacture and when the serial number was
assigned. 1 = 2001, 2 = 2002 etc.
URM Centiva/5, CM-920041, rev. 2.22  TIM GmbH

Table of Contents
1 Introduction 1.1 How to use this manual 1-2

1.2 Symbols used in this manual or on the equipment 1-3
1.3 Abbreviations used in this manual or on the equipment 1-5
2 Safety 2.1 Safety 2-2
3 General description 3.1 General description 3-2

3.1.1 Intended use 3-2
3.1.2 Principle of operation 3-2
3.1.3 Ventilation modes 3-3
3.1.4 Additional function 3-4
3.2 Supply 3-5
3.2.1 Electrical supply 3-5
3.2.2 Gas supply 3-5
3.3 Positioning 3-6
3.4 Main components 3-7
3.5 System controls 3-8
3.5.1 Front side 3-8
3.5.2 Rear side 3-9
4 Concept of operation 4.1 Concept of operation 4-2

4.1.1 Screen content 4-3
4.1.2 Soft keys 4-5
4.1.3 I : E Ratio soft key 4-6
URM Centiva/5, CM-920041, rev. 2.22 0-1

Table of Contents
4 Concept of operation 4.1.4 Timing parameters 4-7

continued 4.1.5 Graphics 4-8
4.1.6 Numerical patient data 4-9
4.1.7 Status information 4-10
4.1.8 ComWheel 4-12
4.1.9 Changing a parameter 4-13
4.1.10 Menu button 4-14
4.1.11 Selecting a menu topic 4-15
4.1.12 Activating a menu function 4-16
4.1.13 Submenus 4-17
4.1.14 Open a submenu 4-19
4.1.15 Change a parameter in a submenu 4-20
4.1.16 Alarm silence 4-22
5 Preparation 5.1 Electrical supply 5-2

5.1.1 Mains supply 5-2
5.1.2 Back-up battery supply 5-4
5.2 Gas supply 5-5
5.2.1 Dual gas supply 5-5
5.2.2 Single gas supply 5-6
5.3 Set up of expiration valve 5-7
5.4 Breathing gas conditioning 5-8
5.5 Breathing circuit 5-9
5.5.1 Connection with HME 5-9
5.5.2 Connection with active humidifier 5-10
5.6 Placing the device 5-12
5.6.1 Control panel 5-12
5.6.2 Entire system 5-14
5.7 Turn ON and OFF 5-15
5.8 Self test 5-16
5.8.1 Power-up test 5-16
5.8.2 System test 5-17
5.8.3 In-operation test 5-18
5.9 Select the type of patient 5-19
5.10 System test menu 5-20
5.11 Starting the ventilator 5-22
0-2 URM Centiva/5, CM-920041, rev. 2.22

Table of Contents
6 Operation 6.1 Adjust ventilation modes 6-2

6.1.1 Select a ventilation mode 6-2
6.1.2 Default ventilation values 6-3
6.1.3 Changing ventilation modes 6-4
6.2 Adjust ventilation parameters 6-6
6.2.1 VCV 6-6
6.2.2 SIMV-VC 6-9
6.2.3 Bi-Level 6-12
6.2.4 Bi-Level/PSV 6-14
6.2.5 CPAP/PSV 6-17
6.2.5 CPAP/Apnea 6-19
6.3 Additional functions 6-21
6.3.1 Standby 6-22
6.3.2 ASR (Automatic Suction routine) 6-24
6.3.3 Parameter menu 6-32
6.3.5 Alarm AUTOSET 6-38
6.3.6 ARC (Airway Resistance Compensation) 6-41
6.3.7 NEB (Nebulizer drug delivery) 6-44
6.3.9 NIV (Non Invasive Ventilation) 6-51
6.3.10 APD (Automatic Patient Detection) 6-53
6.3.11 OCV (Online O2 sensor Calibration) 6-54
6.3.12 Short cuts 6-55
7 Cleaning and Sterilization 7.1 General advice 7-2

7.2 Disassembly 7-3
7.2.1 Used with HME 7-3
7.2.2 Used with active humidifier 7-4
7.3 Expiration valve 7-5
7.3.1 Removing expiration valve assembly 7-5
7.3.2 Disassemble expiration valve assembly 7-7
7.4 Clean and sterilize 7-8
7.4.1 Housing and control panel 7-8
7.4.2 Expiration valve 7-8
7.5 Reassembly 7-9
7.5.1 Reassemble expiration valve assembly 7-9
7.5.2 Reinsertion of expiration valve assembly 7-10
URM Centiva/5, CM-920041, rev. 2.22, 0-3

Table of Contents
8 Alarms and messages 8.1 Alarm modality 8-2

8.2 Alarm messages 8-4
8.3 Other messages 8-8
8.3.1 Messages during power up 8-8
8.3.2 Messages during system test 8-11
8.3.3 Messages during O2 calibration 8-19
8.3.4 Messages during operation 8-20
9 Maintenance 9.1 General 9-2

9.2 Oxygen sensor calibration 9-3
9.2.1 Start calibration 9-3
9.2.2 Stop calibration 9-4
9.3.1 Remove valve assembly 9-5
9.3.2 Replace components 9-7
9.3.3 Reassembly 9-8
9.4 Additional maintenance 9-10
9.4.1 Every twelve (12) months 9-10
9.4.2 Every twenty four (24) months 9-10
10 Technical data 10.1 General 10-2

10.2 Supplies 10-3
10.3 Ventilator characteristics 10-4
10.4 Controls and ranges 10-8
10.6 Measurement functions 10-9
10.7 Monitoring functions 10-10
10.8 Control panel 10-13
11 Parts list 11.1 Spare parts 11-2

11.2 Accessories 11-2

1 Introduction
In this section 1.1 How to use this manual 1-2

1.2 Symbols used in this manual or on the equipment 1-3
1.3 Abbreviations used in this manual or on the equipment 1-5

1 Introduction
1.1 How to use this manual
This manual describes the operation of the
Centiva/5 ICU ventilator

Release 2.2n.
The Centiva/5 ICU ventilator may be used together with additional

accessories, such as trolleys, compressors etc. These accessories
come with a separate operation manual.
Use this manual together with the manuals for optional accessories.

1 Introduction
1.2 Symbols used in this manual or on the equipment
Warnings and Cautions tell you about dangerous conditions

that can occur if you do not follow all instructions in this manual.
WARNING Warnings indicate a condition that can cause injury to the operator or
the patient.
CAUTION Cautions indicate a condition that can cause damage to the

equipment. Read and follow all warnings and cautions.
Alarm silence touch key
Menu touch key
Left turn ComWheel to decrease value
Right turn ComWheel to increase value
Rotate ComWheel to change value
Push ComWheel to confirm selection (ENTER)

1 Introduction
On (power)
Off (power)
Earth ground
Protective earth ground
Equipotential
Type B equipment
Input (Expiratory port)
Output (Inspiratory port)
Attention, refer to product instructions, EN/IEC 60601-1
10101 Serial data transfer connection
Systems with this mark comply with the European Council Directive
(93/42/EEC) for Medical Devices when they are used as specified in
their Operation and Maintenance Manuals. The “xxxx” is the
xxxx certification number of the Notified Body used by the manufacturer’s
Quality Systems.
Nebulizer gas supply
DC external power supply

1 Introduction
1.3 Abbreviations used in this manual or on the equipment
Vent. mode Ventilation mode

VCV Volume constant Controlled Ventilation
SIMV - VC Synchronized Intermittent Controlled Ventilation- volume constant
Bi-Level Bi Level pressure controlled ventilation
PSV Pressure Support Ventilation
CPAP Continuous positive airway pressure
CPAP/PSV CPAP with pressure support ventilation
CPAP/Apnea CPAP with apnea Bi-Level back up ventilation
APD Automatic patient detection

ARC Airway resistance compensation
ASR Automatic suction routine
NEB Nebulizer
NIV Non Invasive Ventilation
OCV Online oxygen calibration during ventilation
Endot.tube Endotracheal tube
Trach.tube Tracheal tube
Pmax Safety pressure setting

Plimit Pressure limit setting
Pinsp Inspiratory pressure setting
PS Pressure Support pressure setting
Ppeak Highest airway pressure, measured within last breath
Pmin Lowest airway pressure, measured within last breath
PPEEP Positive End Expiratory Pressure setting
Paw Airway pressure in general
Rate Breaths per minute

I:E Inspiratory to Expiratory time ratio
Ramp Ramp time between lower and upper Bi-level
PS ramp Ramp time between PEEP level and PS pressure level
Time window Trigger time window
t Time in general
Vt Tidal volume setting

TV Tidal volume, measured
MV Minute volume, measured
I-Flow Inspiratory flow setting
Trigg. Trigger flow required to trigger an assisted breath
Byflow Bias flow
PS endflow End-of-flow criteria for PS pressure support
Flow Flow in general

1 Introduction
Fi-O2 Inspiratory O2 concentration setting

O2-I Inspiratory O2 concentration, measured
I On (power), line supply

O Off (power), line supply
or AC Alternating current
or DC Direct current
Ref Stock number

SN Serial number
Rev. x.nn Software revision number
O2 40 … 80 PSI O2 gas supply input with a pressure range of 40 … 80 PSI

AIR 40 … 80 PSI AIR gas supply input with a pressure range of 40 … 80 PSI
24V/3A DC DC supply input with 24 V and a maximum current of 3 A

Serial Port Connection for serial data transfer

2 Safety
In this section 2.1 Safety 2-2

2 Safety
2.1 Safety
Reference This manual describes the operation of the
URM Centiva/5, CM-920041, rev. 2.22

Release 2.2n.
Safe Operation To ensure safe operation of the Centiva/5 use the system only as
intended. Operators need to be familiar with this Operation Manual
prior to operating the system. Only trained operators are allowed to use
this system. Always ensure compliance with the requirements of this
Operation manual and with the local governmental or other authority’s
requirements for operating ICU ventilators.
Classification The Centiva/5 is a device of group IIb, according to the directive

93/42/EEC, Annex IX, Rule 9 for medical products.
Classification according to EN 60601-1 for electro medical devices
DEVICE OF PROTECTION CLASS I, with internal power supply. Protection

against electrical hazard is performed by grounded operation.
DEVICE TYPE B, according to safety grade for electrical hazard
CONTINUOUS OPERATION according to described operation modes.
Safety standards The Centiva/5 is designed with respect to the following safety
standards:
- EN 60601-1, Medical electrical equipment, General
conditions
- EN 794-1, Special requirements for lung ventilators
- EN 475, Specification for warning, advice and information in
anesthesia and critical care
- EN 60601-1-4, software controlled medical devices
- EN 60601-1-2, electro magnetic compatibility

2 Safety
Safety features The following safety features are built into the Centiva/5 to warn the
operator in case of risk to the patient.
Device alarms
Control of Control for
Gas supply O2 supply fail, AIR supply fail
Disconnection Disconnection of patient and breathing
system
O2 concentration O2 concentration
Electrical energy Line supply fail, battery supply fail
Device’s control system Watchdog alarm
Patient alarms
Control of Control for
High pressure High pressure alarm
Minute volume Upper and lower minute volume alarm
Rate Upper and lower rate alarm
Airway pressure Pressure sustained
Patient Safety The Centiva/5 shall be operated by or on the order of a physician. The
Centiva/5 shall only be operated by qualified medical personal, to
ensure adequate intervention in case of a device malfunction.
Constant surveillance of a patient connected to an ICU ventilator by
trained personal is required.
Ensure alarm limits are set according to the patient’s situation and
ensure alarms are activated whenever a patient is connected to the
system.
Use only breathing circuits and accessories approved by the

manufacturer of either the Centiva/5 or the accessory.

2 Safety
Patient Safety (cont.) Always perform the Centiva/5’s system test before using the ventilator.
WARNING Never perform a system test when a patient is connected to the

Centiva/5.
This system test is designed to test all safety relevant features and
components prior to the start of ventilation.
In case of emergency the system test may be bypassed. The system will
recognize this status as “No test” and displays this status in the screen
to remind the operator to perform the system test at their earliest
convenience.
If the system test is not performed, the system does not know the
correct breathing circuit’s specifications necessary for optimized
compliance and resistance compensation. In this case the ventilator
may not work with the specified accuracy and tolerances.
Residual risk To reduce the risk of a device malfunction, redundant systems are
integrated into the Centiva/5.
High and medium risk functions are designed to provide an alternate
system in case of a first failure.
Low risk functions are tested with the power-up test each time the unit
is powered up prior to operation.
The system provides for an adjustable pressure limiter in the VCV and
SIMV –VC modes. In the VCV or SIMV-VC modes the Plimit defaults to 20
cmH2O in Pediatric and 30 cmH2O in Adult mode.
The system has an additional second level safety pressure function,
Pmax, that is active in all modes. The Pmax defaults to 30cmH2O in
Pediatric and 40 cmH2O in the Adult mode, when in the VCV or SIMV-VC
modes. The Pmax default is set to 18 cmH2O in Pediatric and 21 cmH2O
in the Adult mode, when in Bi-Level, CPAP/PSV or CPAP/Apnea modes.

2 Safety
Risk of electrical hazard The Centiva/5 is designed to be operated only in electrical

environments according to VDE 0107 or EN 60601-1.
Prior to cleaning, repair or maintenance always disconnect the system
from the electrical supply. Prior to reconnecting the system to the
electrical supply ensure the housing is dry.
Prior to connecting the device to an electrical supply check your local
supply voltage to match the operation voltage of the device, which is
marked on the serial plate on the rear side of the device.
Store the system only according to the given specifications for
temperature and humidity.
Operate the system only according to the given specifications for
temperature and humidity. In case system’s temperature is lower or
higher than specified, allow the system to stabilize for one hour before
operation.
Do not use materials such as Ammonia, Phenol or Acetone to clean this
device.
Do not use the Centiva/5 when there is doubt in the proper function of
the electrical earth ground in the installation environment
Fire hazard Do not use the Centiva/5 in the presence of flammable anesthetics.
Risk of electromagnetic Devices radiating electromagnetic fields in a strength beyond the

interference requirements of EN 60601-1-2 can influence the safe operation of the
Centiva/5 and can cause risk to the patient.
Devices radiating high frequency fields and installed near the system
can influence the safe operation of the Centiva/5 and can cause risk to
a patient.
Do not use cellular phones (mobile phones) within 10 meters of the
Centiva/5. Otherwise this may result in a possible influence on the safe
operation of the device and can cause risk to a patient.
Do not use the Centiva/5 in the presence of nuclear magnet resonance
devices (NMR, MRI).

2 Safety
Accessories The Centiva/5 has a wide range of accessories available.

Use only accessories that are listed in the Centiva/5 accessories list.
Prior to connecting a network or any other data management transfer
system to the serial output of the Centiva/5 verify that these devices
are in compliance with EN 60950 standard for data transfer safety, or
EN 60601-1 medical electrical equipment.
The person connecting other systems (electrical or other) to Centiva/5
is responsible that the entire system meets the requirements of EN
60601-1.
Monitoring The Centiva/5 is equipped with monitoring features that will help to
monitor and control the patient’s ventilation situation and to detect
changes in the ventilation parameters.
Changes in the ventilation parameters can be caused by:
• changes in the patient’s status
• changes in the settings
• failure in operation
• device malfunction
• changes in the electrical supply
• changes in gas supply
A resuscitator for manual ventilation shall be present to maintain
ventilation in case of a device malfunction.
Service and maintenance The Centiva/5 shall be checked at least every twelve months for safety
and proper function.
Only authorized service personal shall perform repair, service and
maintenance to the device.
The maintenance intervals and procedures are documented in section
9, ”Maintenance”.

2 Safety
Responsibility of the The manufacturer is not responsible for any function change, damage
manufacturer or injury to patient or operator that is caused by misuse or by disregard
of the safety advices mentioned in this manual.
The user or owner is responsible for the function of the system if the
device is serviced, maintained or repaired by unauthorized personnel.
The user or owner is responsible for the function of the system if the
device is misused or not used according to the instructions in this
Operation manual .
Manufactured by Salvia Lifetec GmbH & Co KG

Niederhöchstädter Strasse 62
61476 Kronberg
Germany
0123
Manufactured for Datex-Ohmeda Inc.
Ohmeda Drive
P.O. Box 7550
Madison, WI 53707-7550
USA
Phone. +1 608 221 1551
Fax: +1 608 223 2476

2 Safety
Notes

3 General description
In this section 3.1 General description 3-2

3.1.1 Intended use 3-2
3.1.2 Principle of operation 3-2
3.1.3 Ventilation modes 3-3
3.1.4 Additional function 3-4
3.2 Supply 3-5
3.2.1 Electrical supply 3-5
3.2.2 Gas supply 3-5
3.3 Positioning 3-6
3.4 Main components 3-7
3.5 System controls 3-8
3.5.1 Front side 3-8
3.5.2 Rear side 3-9

3.1 General description
3.1.1 Intended use Centiva /5 is a critical care ventilator used for intensive care ventilation
of humans.
This ventilator is intended to be used for adult patients and children age
1 year + or bodyweight greater than or equal to 5 kg.
This ventilator is designed to maintain and support existing and
returning patient’s spontaneous breathing.
3.1.2 Principle of Centiva/5 is a time controlled, volume constant, pressure cycled,

operation software controlled system.
The expiration valve is electromechanically controlled with a locking
system to provide proper seating of the PEEP valve assembly.
The system uses a flow trigger and allows patient’s free breathing over a
built-in free breathing valve.
The system provides for a permanent Byflow in the breathing circuit and
allows patient’s spontaneous breathing in all modes.

3.1.3 Ventilation modes VCV (Volume Controlled Ventilation)

Controlled volume constant ventilation with the ability of patient’s
spontaneous breathing between the mandatory breaths.
Additional capabilities are:
- PLV - Pressure Limited Ventilation
- IRV - Inverse Ratio Ventilation
SIMV - VC (Synchronized Intermittent Mandatory Ventilation – Volume

Constant)
Synchronized volume constant ventilation with the ability of patient’s
spontaneous breathing in between the mandatory breaths.
- PLV - Pressure Limited Ventilation
- PSV - Pressure Support Ventilation
Bi-Level (Bi-Level)
Synchronized pressure controlled ventilation combined with patient’s
free spontaneous breathing during the entire breathing cycle.
- PSV - Pressure Support Ventilation on lower Bi-Level pressure level
CPAP/PSV (Continuous Positive Airway Pressure/ Pressure Support

Ventilation)
Spontaneous breathing with environmental pressure or positive airway
pressure.
- PSV - Pressure Support Ventilation on CPAP pressure level
CPAP/Apnea (Continuous Positive Airway Pressure / Apnea back-up)

Spontaneous breathing with environmental pressure or positive airway
pressure with PSV - Pressure Support Ventilation on CPAP pressure
level
- Bi-Level back up ventilation mode with pre-adjusted settings if patient
activates the apnea alarm.
For more details refer to section 6 “operation”.

3.1.4. Additional functions APD (Automatic Patient Detection)

Function that provides automatic detection of a patient being
connected to the ventilator in all ventilation modes.
ARC (Airway Resistance Compensation)

Function that provides adjustable inspiratory and expiratory
compensation of the tube’s resistance in all spontaneous breathing
modes to ease patient’s spontaneous breathing.
ASR (Automatic Suction Routine)

Function that provides an automatic procedure for bronchial suction
preparation with a pre-oxygenation phase, a pressure free opening of
the y-piece and a post-oxygenation with automatic return to previous
settings in all ventilation modes.
NEB (Nebulizer drug delivery)

Function that provides drug delivery in all ventilation modes to the
patient via the breathing circuit by means of a so called “jet nebulizer”.
NIV (Non-Invasive Ventilation)

Function that provides leakage compensation in all ventilation modes
to allow ventilation of leaking systems such as nasal or face mask ,
larynx mask or uncuffed tubes.
OCV (Online O2 sensor Calibration during Ventilation)

Function that allows O2 sensor calibration during ventilation.

3.2 Supply
3.2.1 Electrical supply The Centiva/5 can be configured to be supplied with electrical power
from a line supply voltage of 230 V or 115 V AC.
The Centiva/5 can be supplied by a 24 V DC external battery pack

(option) for e.g. inner clinical transportation purposes.
As a back-up supply Centiva/5 is provided with an internal battery that

supports operation for a minimum of 30 minutes (battery fully charged).
3.2.2 Gas supply The Centiva/5 is designed to be supplied with O2 and AIR. Single gas
operation with either AIR or O2 can be selected .
Special notice Ensure clean and dry medical gas supply sources.
3.3 Positioning
The Centiva/5 is design to be positioned on

• a trolley or cart (option)
• a rail mount (option)
• a ceiling pendulum (option)
The control panel of Centiva/5 is tiltable and detachable. The control

panel can be mounted up to a 3 meter distance from the main engine
(remote control).
Special notice Ensure the Centiva/5 is securely mounted.

3.4 Main Components
The Centiva/5 is a system that can be separated into three (3) user
accessible components
• The main engine
• The control panel
• The expiration valve
These three assemblies can be separated by the user without using any
tools.
Main engine
Control panel
Expiration valve

3.5 System controls
3.5.1 Front side
Centiva/5
Bi-Level Tube : E 7.5 50% Adult
15 MV-E 12 Alarm lights
5.2Liter2
10
Vt-E
5
350 mL
Ppeak 21
Paw 14cmH2O
Screen
cmH2O
40
Pmin
Silencer
3cmH2O
20
Flow O2-I 25
L/min 21 18
%
-20
-40
Rate
181/min
40
8 Menu key
Fi02 Rate I:E Ramp P-Insp PEEP PS
21 12 1:2 0.2 10 3 5
% 1/min sec cmH2O cmH2O cmH2O
ComWheel
Soft keys
O
Stopper
Insp. port
Nebulizer
Exp. port
ON/OFF

3.5.2 Rear side
Serial plate
Caution. U.S. Federal laws restrict this device

to sale by or on the order of a licensed medical
practitioner.Outside the U.S.A. check local
laws for any restriction that may apply.
Lin
es
wi
O2
AI
tc
R
h
ga
ga
O2 AIR
si
24
Co
Gr
Lin
si
280 ... 600 kPa or 40 ... 80 PSI

nle
ou
nl
m
ei
VD
et
nd
t
po
nl
C
et
rt
co
in
24V/3A DC
let
n.

4 Concept of operation
In this section 4.1 Concept of operation 4-2

4.1.1 Screen content 4-3
4.1.2 Soft keys 4-5
4.1.3 I : E Ratio soft key 4-6
4.1.4 Timing parameter 4-7
4.1.5 Graphics 4-8
4.1.6 Numerical patient data 4-9
4.1.7 Status information 4-10
4.1.8 ComWheel 4-12
4.1.9 Changing a parameter 4-13
4.1.10 Menu button 4-14
4.1.11 Selecting a menu topic 4-15
4.1.12 Activating a menu function 4-16
4.1.13 Submenus 4-17
4.1.14 Open a submenu 4-19
4.1.15 Change a parameter in a submenu 4-20
4.1.16 Alarm silence 4-22

4.1 Concept of operation
The Centiva/5 is a menu operated and software controlled system.

All information for control is provided by the Display.
All controls are located on the front panel, except the On-Off button on
the lower front right and the line supply switch on the rear.
The principle for all controls is based on the S A C system.
Select
There are two ways to select a parameter to change, either by
soft keys or by menu.
Adjust
The adjustment is always made by turning the ComWheel
clockwise for up and counterclockwise for down.
Confirm
Confirmation of the adjusted value for the selected parameter
is made by pushing the ComWheel.
Centiva/5
15 MV-E 12
5.2Liter2
10
Vt-E
5
350 mL
Ppeak 21
Paw
14cmH2O
Screen
cmH2O
40
Pmin
3 cmH2O
20
Flow O2-I 25
L/min 21 18
%
-20
-40
Rate
181/min
40
8 Menu key
21 12 1:2 0.2 10 3 5
ComWheel
Soft keys

4.1.1 Screen content The Centiva/5 display shows all information on a color LCD screen. The
screen is divided into four different areas.
Soft key parameters Area # 1. Area # 4 Status information
This area shows the

ventilation parameter
settings aligned with Area # 2 Area # 3
the specific soft key.
Graphical patient data numerical
For details refer to and alarm messages patient
soft keys. data
Area # 1
Softkeys for ventilation parameter settings
Graphics Area # 2 Area # 4 Status information
This area shows the

measured patient
data in graphical Area # 2 Area # 3
format as well as Graphical patient data numerical
alarm messages. and alarm messages patient
data
Area # 1
Numerical data Area # 3 Area # 4 Status information
This area shows the

measured patient
data in numeric Area # 2 Area # 3
format. Graphical patient data numerical
and alarm messages patient
data
Area # 1

Status information Area # 4. Area # 4 Status information
This area shows the

status information for
the ventilator. Area # 2 Area # 3
Graphical patient data numerical

and alarm messages patient
data
Area # 1

4.1.2 Soft keys By using the soft keys the operator selects a parameter to change.
Depending on the current ventilation mode the soft keys are related to
different parameters. Immediately above the soft key the parameter is
displayed in the screen showing the value and units of measure.
Fi O2 Rate I:E Vt Plimit PEEP I-Flow

Soft keys in VCV 50 10 1:2.0 110 30 OFF 6.6
% 1/Min mL cmH2O cmH2O L/Min
Fi O2 Rate I:E Vt Plimit PEEP PS

Soft keys in SIMV - VC 50 10 1:2.0 110 30 OFF 10
% 1/Min mL cmH2O cmH2O cmH2O
Fi O2 Rate I:E Ramp P-Insp PEEP PS

Soft keys in Bi-Level 50 10 1:2.0 0.20 10 OFF 10
% 1/Min Sec. cmH2O cmH2O cmH2O
Fi O2 Ramp PEEP PS
Soft keys in CPAP/PSV
50%
0.20
Sec.
OFF
cmH2O
5
cmH2O

Soft keys in CPAP/Apnea
50
%
10
1/Min
1:2.0 0.20 Sec.
10
cmH2O
OFF
cmH2O
10
cmH2O
The soft key shows parameter (type) and value Type

(Val) with blue characters on yellow background.
Val
unit
Activating a soft key will change the background
color from yellow to blue and the character from
blue to yellow. When changing the parameter with
c-val
the ComWheel, the current parameter is displayed
as a small character on top to remind the operator
N-val
type
of the value (c-val) while making the new
parameter change (N- val). After confirming the changed value the soft
key returns to blue character on yellow background.

4.1.3 I : E ratio soft key For standard I : E ratio settings from 1:1 to 1:9.9 the I : E ratio soft key‘s
characters and background colors are identical to the other soft keys.
Inverse I:E ratio When changing the I : E ratio in all ventilation

modes to inverse values (I>E) (range 1:1 to 4:1) 1:2.0
the user will be notified by a change of the
background color from blue to red and the
2.0:1
I:E
character color from yellow to white. After
confirming the changed value the soft key returns to blue character on
yellow background.
Inverse I:E ratio in SIMV-VC mode Changing the soft key parameter rate in the SIMV-
I:E
VC mode causes a change of the I:E ratio
accordingly to keep the ventilation pattern similar.
When this change in I : E ratio leads to inverse
2.0:1
values (I>E) the user will be notified by a change
of the background color from blue to white and the character color from
yellow to red. After confirming the changed value the soft key returns to
blue character on yellow background.
APRV I:E ratio in Bi-Level mode Only in Bi-Level mode Centiva/5 offers extreme 3:1.0
inverse I:E ratio values to simulate APRV (airway
pressure release ventilation). 9.9:1
I:E
When changing the I : E ratio in Bi-Level mode
beyond the inverse I:E ratio level to extreme inverse I:E ratio values
(range 4:1 to 9.9:1) the user will be notified by a change of the
background color from red to brown. After confirming the changed value
the soft key returns to blue character on yellow background.
Note When changing the ventilation mode from Bi-Level to any other mode,
APRV I:E ratios will not transfer automatically, but the user will be
notified to correct the I:E ratio accordingly by a message “I :E > 4:1 !”.

4.1.4 Timing parameter The Centiva/5’s timing parameter in all ventilation modes are:
- ventilation rate (rate)
- inspiration to expiration time ratio (I:E)
TVFi O2 Rate I:E Vt Plimit PEEP I-Flow
50%
10
1/Min
1:2.0 110 mL
30
cmH2O
Off
cmH2O
6.6
L/Min
Changing the I-Flow setting in the ventilation modes VCV and SIMV-VC
has an impact on the timing, too. In this case the inspiratory pause will
be affected by this parameter.
All timing parameters are relative parameters and do not directly set
absolute times. During changing the setting of one of the timing
parameters Centiva/5 will display the absolute time information on the
screen in the format:
I=xx s, P=yy %, E= zz s
„I“ is inspiration time (Tinsp) in seconds
„P“ is inspiratory pause in % of inspiration time (Tpause / Tinsp)
„E“ is expiration time (Texsp.) in seconds.
After confirming made changes to one of the timing parameters this
absolute time message in the screen disappears automatically.
I= 2.0 s, P= 30%, E=3.0 s

4.1.5 Graphics The Centiva/5 displays two graphical waveforms on the screen:
- current airway pressure versus time
- current airway flow versus time
The upper waveform shows the airway pressure and contains markers
for the pressure settings, such as PEEP, Pinsp or Plimit.
The lower waveform shows the airway flow.
The display will automatically change to scale to maximize readability of
the waveform.
The graphic waveform data is real time and both waveforms are
synchronized on the same time base.
15
10
Paw
cmH2O
40
20
Flow
L/min
-20
-40

4.1.6 Numerical patient The Centiva/5 displays measured patient data in a numeric format.
data
The expiratory minute volume is measured MV-E 12.0
over a period of 60 secs or 10 breaths. 2.5
3.0 Liter
The expiratory tidal volume is measured TV-E

during each breath.
361 mL
The maximum (Peak) airway pressure is Ppeak 21

measured during each breath.
14 cmH2O
The minimum (Min) airway pressure is Pmin

measured during each breath.
1 cmH2O
The inspiratory O2 concentration is measured O2-I 26

at the inspiratory port. 18
21 %
The total patient breath rate is measured over Rate 40

a period of 60secs or 10 breaths and 8
represents spontaneous plus mechanical
breaths.
10 1/min
The format of this numeric data field shows Para UL

the parameter (Para) with the measured value LL
(Val) and the unit of measure (unit). Val Unit
If alarm limits for this particular parameter are available, the upper limit
(UL) and the lower limit (LL) are displayed in the same data field.

4.1.7 Status information The Centiva/5 shows status information in the top portion of the
display. The following describes the status information in order from left
to right appearing on the screen.
Vent. mode The selected ventilation mode is displayed:

“VCV”, “SIMV-VC”, “Bi-Level”, “CPAP/PSV”, Bi-Level
“CPAP/Apnea”.
NEB When nebulization is activated, an icon is displayed

during operation in nebulization mode
ARC When Airway Resistance Compensation is

activated, status information is displayed Tube: E 7.5 40%
giving the selected tube (E=endotracheal,
T= tracheal), size of tube (e.g. 7.5 mm) and level of compensation (e.g.
40%). If ARC is not turned ON this status information field is not
present.
Battery When the system is supplied by the internal

back-up battery the remaining operation Battery: 28 min
time on battery is displayed. Whenever the
internal battery is being charged, the same status information appears.
If the system is supplied by line (main) supply and the battery is fully
charged this status information field is not present.
Patient type Status information about the selected patient type

is displayed with either ”Adult” or “Pedia” Adult
(pediatric).
System Test When the System test is not performed and the
ventilator is started by bypassing the system test, No Test
the “No Test” is displayed. If the system test was
performed prior to the start of the ventilation this status information
field is not present.

Single gas supply If the operator has confirmed single gas operation
during the system test, this status information Only O2
field displays “Only AIR” for single gas supply with
AIR or “Only O2” for single gas supply with O2. If dual gas supply with
O2 and AIR is confirmed this status information field is not present.
ASR When the Automatic Suction Routine is activated

Pre oxygen
the status information field reports the different
phases of the ASR procedure:
- “Pre oxygen” for the pre-oxygenation phase,
- “Suction” for the suction phase,
- “Post oxygen” for the post oxygenation phase.
If ASR is not turned ON this status information field is not present.
Shut down When the

Switch off device ? Yes: Enter, No: any button
“System
Open?” message is displayed on the screen and the ON-OFF button is
activated for longer than 3 seconds, the shut down status information
appears. This shut down information indicates that pushing the
“<Enter>” button (ComWheel), powers down the Centiva/5 or by
pressing any other button the system remains in the normal operation
mode. This status information field overwrites all other status
information fields and covers the entire status information area on the
screen
External DC supply When an external DC supply (e.g. battery pack)

takes over the mains supply, an icon is displayed to
indicate the power supply by external battery.

4.1.8 ComWheel The ComWheel is turned to change the selected parameter values .
Turing clockwise increases the value or moves up the

cursor in a menu.
Turning counterclockwise decreases the value or

moves down the cursor in a menu.
Pushing the ComWheel confirms a selection.

Confirming a selection returns the soft key background
color from blue to yellow or changes the highlighted area
in a menu. The changed parameter will only become
valid when the ComWheel is pushed for confirmation.
Special notice When a screen message asks for “<Enter>”, the system asks the
operator to push the ComWheel to confirm an action.

4.1.9 Changing a The following shows how a parameter change is made.

parameter
FiO2
This is the parameter field before we start.
30
%
Select the FiO2 soft key. 30

Notice the color change.
30
FiO2
Turn the ComWheel clockwise to increase the value to

50%.
Notice the value change.
The current value is shown on the top and the new 30

value in the middle.
50
FiO2
Confirm the selection by pushing the ComWheel.
This is the parameter field after the change.

FiO2
50
%

4.1.10 Menu button To select additional functions or infrequently used parameters push the
menu button.
Within the Centiva/5’s screen the

main menu will open. It is here
Stand-by ON
that most functions are directly
accessible. ASR ON
Submenus can be opened for Parameter menu
detailed parameter settings.
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit

4.1.11 Selecting a menu To select a specific menu topic turn the ComWheel to select the menu
topic option and push the ComWheel to confirm the selection.
Turning the ComWheel clockwise will move the cursor

up the menu.
Turing the ComWheel counterclockwise will move the

cursor down in the menu.
Pushing the ComWheel will confirm the selection

4.1.12 Activating a menu The following shows how to activate a menu selection.
function
Open the main menu by pushing the menu button.
Stand-by ON
The main menu will appear in the screen. ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
Rotate the ComWheel to select the Alarm AUTOSET

function.
Stand-by ON
ASR ON
The selected function will be highlighted in the Parameter menu
menu. Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
The function “Alarm AUTOSET” is activated and the

menu closes automatically.

4.1.13 Submenus The following selections in the main menu open the submenus :
• Parameter menu
• Alarm limits
• Ventilation modes (Vent. Modes)
• Airway Resistance Compensation (ARC)
These submenus open upon selecting the topic in the main menu.
Stand-by ON
ASR ON
Parameter menu Parameter menu I-flow 10.0 L/m
Alarm limits PS ramp 0.20 s
Alarm AUTOSET Trigg. 3.0 L/m
Vent. modes ByFlow 3.0 L/m
ARC Time window 60%
Nebulizer ON PS endflow 25%
System test Buzzer 100%
Exit Previous menu
Exit
Stand-by ON
ASR ON
Parameter menu
Alarm limits Alarm limits MV max 1.7 L

Alarm AUTOSET MV min 0.5 L
Vent. modes Leakage 25%
ARC Pmax 40cmH2O
Nebulizer ON Apn.del. 20 Sec
System test Rate max 40/Min
Exit Rate min 8/Min
Previous menu
Exit

Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes Vent. modes VCV
ARC SIMV - VC
Nebulizer ON Bi-Level
System test CPAP/PSV
Exit CPAP/Apnea
Previous menu
Exit
Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC ARC Endot.tube OFF

Nebulizer ON Trach.tube OFF
System test Diameter 7.5
Exit Compensat. 75 %
Previous menu
Exit

4.1.14 Open a submenu Push the Menu button to open the main menu,
Stand-by ON
Select the “Vent. modes” by opening the main

ASR ON
menu and rotating the ComWheel to the “Vent. Parameter menu
Modes” selection. Alarm limits

Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
Confirm this selection by pushing the ComWheel which

opens the “Vent. Modes” submenu.
VCV
The “Vent. modes” submenu allows you to select SIMV - VC
the appropriate ventilation mode by rotating the Bi-Level
ComWheel and confirming the selection by CPAP/PSV
pushing the ComWheel. CPAP/Apnea

Previous menu
Exit

4.1.15 Change a The following shows how to change the parameter “MV max” in the
parameter in a sub menu alarm limit submenu.
Stand-by ON
The main menu will appear in the screen. ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
Select the “Alarm limits” by rotating the ComWheel.
Stand-by ON
The selected function will be highlighted in the ASR ON
menu. Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
Confirm the selection by pushing the ComWheel. The

“Alarm limits” sub menu will open.

MV max 1.7 L
MV min 0.5 L
Leakage 25%
The “Alarm limits” submenu opens. Pmax 40cmH2O

Apn.del. 20 Sec
Rate max 40/Min
Rate min 8/Min
Previous menu
Exit
Select the “MV max” by rotating the ComWheel.
MV max 1.7 L
MV min 0.5 L
Leakage 25%
The selected function will be highlighted in the Pmax 40cmH2O
menu. Apn.del. 20 Sec

Rate max 40/Min
Rate min 8/Min
Previous menu
Exit
Confirming the selection highlights the value in the “MV

max” setting.
MV max 1.7 L
The selected parameter value is highlighted.

MV min 0.5 L
Leakage 25%
Pmax 40cmH2O
Apn.del. 20 Sec
Rate max 40/Min
Rate min 8/Min
Previous menu
Exit

Rotating the ComWheel adjusts the new value.
MV max 2.5 L
The MV max is changed to 2.5 L. MV min 0.5 L

Leakage 25%
Pmax 40cmH2O
Apn.del. 20 Sec
Rate max 40/Min
Rate min 8/Min
Previous menu
Exit
Confirming the selection activates the new value for

the alarm limit MV max.
MV max 2.5 L
MV min 0.5 L
Selecting the “Previous menu” selection returns Leakage 25%
you to the main menu. Confirming the “exit” Pmax 40cmH2O
function will close the menu window or if left open Apn.del. 20 Sec
for 30 secs the menu will automatically close.
Rate max 40/Min
Rate min 8/Min
Previous menu
Exit
4.1.16 Alarm silence Pushing the alarm silence button during a high priority
alarm silences the audible alarm for two (2) minutes. A
clock in the screen starts displaying the remaining alarm
silence time. When an alarm becomes inactive , the alarm message
stays on the screen, but changes color from red to yellow and the
audible alarm turns OFF. This is to remind the operator that an alarm
situation had occurred . Pushing the alarm silence button again will
remove the yellow alarm message from the screen.

5 Preparation
In this section 5.1 Electrical supply 5-2

5.1.1 Mains supply 5-2
5.1.2 Back-up battery supply 5-4
5.2 Gas supply 5-5
5.2.1 Dual gas supply 5-5
5.2.2 Single gas supply 5-6
5.3 Set up of expiration valve 5-7
5.4 Breathing gas conditioning 5-8
5.5 Breathing circuit 5-9
5.5.1 Connection with HME 5-9
5.5.2 Connection with active humidifier 5-10
5.6 Placing the device 5-12
5.6.1 Control panel 5-12
5.6.2 Entire system 5-14
5.7 Turn ON and OFF 5-15
5.8 Self test 5-16
5.8.1 Power-up test 5-16
5.8.3 In-operation test 5-18
5.9 Select the type of patient 5-20
5.11 Starting the ventilator 5-22

5 Preparation
5.1 Electrical supply
The Centiva/5 is designed to operate from electrical supplies:

• Mains supply
• External battery.
The system will treat all of these supply sources as a main supply.
5.1.1 Mains Supply Verify your local mains supply voltage matches the rated device’s
voltage on the serial plate (rear side).
Serial plate

Lin
es
wi
tc
h
O2 AIR
Lin
280 ... 600 kPa or 40 ... 80 PSI

ei
nl
et
24V/3A DC
Connect the power cord to the mains inlet on the rear of the device.
Connect the power cord to the wall outlet.
Switch ON the mains switch.
Verify the ON-OFF button on the front is lit.

5 Preparation
External battery Place the external battery (option) below the Centiva/5 housing and
lock the battery housing to the Centiva/5 housing .

O2 AIR
24
280 ... 600 kPa or 40 ... 80 PSI

VD
C
in
24V/3A DC
let
Locking
Out: 24V/ In: 27,5V/ 3,15 A T

3 A DC 0,25 A DC
Connect the DC supply power cord from the external battery pack to the
blue inlet and verify proper locking of the connector.
Special Notice Verify the ON-OFF button on the front is lit.
Verify the external battery is fully charged prior to usage. When fully
charged the battery’s charging indicator is lit permanently in green.
When powered by the external battery pack, Centiva/5

displays an battery icon in the top left of the screen
For more details to the external battery refer to the operation manual of
this accessory.

5 Preparation
5.1.2 Back-up battery The Centiva/5 is equipped with an internal back-up battery supply that
supply provides at least 30 minutes of operation upon loss of electrical main
supply.
This back-up supply will automatically switch on whenever the main
supply is lost and will maintain uninterrupted operation of the
Centiva/5.
When operating on the back-up battery, the system will display a
message in the operation screen (no line supply).
At the same time the battery status in the
status line of the screen will display the
Battery 28 min
remaining operation time on battery.
When operating on back-up battery the system reduces power
consumption to save energy for extended battery life by turning off the
expiration valve heating system and by reducing the screen brightness.
Upon restoring line (main) supply the system automatically switches
back to the line supply and changes the message in the screen (no line
supply) from red to yellow.
Upon restoring line (main) supply the system automatically starts
recharging the internal battery.
Special notice Whenever the Centiva/5 is supplied by any main supply (line, 24 VDC
or external battery) and the system is turned ON, the internal back-up
battery is recharged. The recharging process is indicated by the battery
status displayed in the status line of the screen (with the timer counting
up ). The re-charger is not active when the system is turned OFF.
WARNING Do not use the internal back-up battery as a main supply.

When turning the Centiva/5 ON without line (main) supply, the system
powers up on the back-up battery to allow opening of the system test
menu only, (e.g. to release the expiration valve for cleaning purpose).
Without line (main) supply the Centiva/5 will not go into a ventilation
mode. After having passed the power-up test and the system test, the
back-up battery function is activated and will perform uninterrupted
operation upon loss of line (main) supply.

5 Preparation
5.2 Gas supply
5.2.1 Dual gas supply The Centiva/5 is equipped with an electronic O2/AIR mixer to provide a
wide range of inspiratory oxygen concentrations. This requires the
supply of both O2 and AIR gases. The gas supply range for both gases
ranges from 40 to 80 PSI. The Centiva/5 is protected against
overpressure up to 140 PSI. The Centiva/5 provides high peak flow
capability for optimized pressure support ventilation. This capability
requires a flow of 120 l/min per gas.
Verify your gas supply pressure matches the pressure range mentioned
above.

O2
AI
R
ga
ga
O2 AIR
si
si
280 ... 600 kPa or 40 ... 80 PSI

nle
nl
et
t
24V/3A DC
Connect the O2 gas supply hose to the O2 gas inlet on the rear of the
device. Connect the O2 gas supply hose to the wall outlet and check
the connection for leaks.
Connect the AIR gas supply hose to the AIR gas inlet on the rear of the
device. Connect the AIR gas supply hose to the wall outlet and check
the connection for leaks.
WARNING Use only gas supply hoses in compliance with the local
standards. Incorrect connecting of O2 and AIR supply can result
in risk to the patient.
WARNING Only supply the system with dry and clean gases to prevent water,
oil or particles to enter the system. Dirt, water or oil can damage
the system and may result in risk to the patient.

5 Preparation
5.2.2 Single gas supply The Centiva/5 needs at least 40 PSI from the gas supply for proper
operation. If this pressure level is not sufficient from one gas source the
system automatically switches to the gas supply which has sufficient
pressure and displays an alarm message on the screen.
The Centiva/5 can operate with a single gas supply without alarms.
When the system recognizes the single gas supply during the system
test it prompts a message on the screen and asks for single gas
operation.
In the event of a single gas supply (e.g. AIR) the following screen will
appear during system test.
Restoring the O2
supply at this time in Centiva/5
the system test
System test Rev. x.nn
removes the message
automatically and the No O2 gas supply
Check O2 gas supply or
system test proceeds. for single gas AIR-supply press <Enter>
Confirming the single

gas operation for AIR-
supply by pushing the
ComWheel to <Enter>
will cause the system test to proceed , but all tests that use O2 will be
skipped .
After the system test is completed and ventilation has started, the
system will change the default setting for FiO2 according to the selected
single gas operation to avoid nuisance alarms. In the single gas AIR
operation the FiO2 default is 21 %. In the single gas O2 operation the
FiO2 default is 100%.
The single gas operation is displayed in the status OnlyAIR
line with "Only Air" when lacking O2 supply or “Only
O2” when lacking AIR supply. Only O2
Special notice Restoring the missing gas during operation allows the unit to operate in
the dual gas supply mode . The system will still display the selected
single gas supply mode until a new system test is performed with both
gases available.

5 Preparation
5.3 Set up of expiration valve
The Centiva/5’s expiration valve is removable from the device for easy
cleaning. Upon re-insertion it will lock in automatically for safe
operation.
The valve assembly consists of three components:

• the valve block
• the PEEP membrane
assembly
• the membrane plate
Verify the PEEP membrane assembly is inserted in the valve block with
the note “TOP” facing you.
Verify the membrane plate (stainless steel) is positioned on top of the

membrane assembly.
The expiratory valve assembly

should slide easily into the
mating slot on the side of the
ventilator
Special notice The expiration valve assembly should be inserted smoothly . If you feel
a high resistance when inserting the assembly do not force it in but
check for proper assembly of the expiration valve.

5 Preparation
5.4 Breathing gas conditioning
An intubated patient’s physiological function for heating and

humidifying the breathing gases is bypassed while on a ventilator.
Therefore, it is necessary to care for this missing function by using either
a passive heat and moisture exchanger (HME) or an active heated
humidifier.
The use of high efficient humidification and heating with low flow
resistance is preferred.
CAUTION Do not use active and passive humidification at the same time in
the same breathing circuit !

5 Preparation
5.5 Breathing circuit
The Centiva/5 ventilator can be used with all approved breathing

circuits and components, noted in the Centiva/5 accessories list.
In pediatric ventilation, in general (tidal volumes less than 300 ml), the
use of pediatric breathing circuits is preferred.
To avoid restriction of the ventilator’s performance, use of breathing
circuits with low resistance and a flow optimized y-piece is preferred.
During the system test, compliance, resistance and leakage rate of the
breathing circuit is measured and displayed.
WARNING Do not use antistatic or conductive tubes or breathing circuits.

Risk of electrical hazard to the patient !
Use of a support arm (option) to hold up the breathing circuit between

the device and patient is recommended.
5.5.1 Connection with Connect inspiratory tube to the right, front 22 mm

HME connector (inspiratory output).
Connect expiratory tube to the left, front 22 mm connector

(expiratory input).
Connect y-piece to open end of inspiratory and expiratory tube
Connect HME to the y-piece Centiva/5
and connect patient to the Bi-Level / ASB

15
Tube : E 7.5 50% Adult
MV-E 12
4.2Liter2
HME.
10 Vt-E
5
350 mL
Ppeak 21
Paw 14cmH2O
Check for proper seating of

mbar
40 Pmin
3cmH2O
20
Flow O2-I 25
all connections.
L/min 21 18
%
-20
Rate 40
-40 121/min8
Fi02 Rate I:E Ramp P-Insp PEEP P-ASB
21 12 1:2 0.2 10 3 5
HME Exp. line Insp. line

5 Preparation
5.5.2 Connection with Adjust the humidifier rail of the Centiva/5
active humidifier cart according to the height

Bi-Level / ASB Tube : E 7.5 50% Adult
15 MV-E 12
4.2Liter2
10
requirement of the active

Vt-E
5
350 mL
Ppeak 21
Paw
mbar
14cmH2O
humidifier so that between the

40
Pmin
3cmH2O
20
Flow O2-I 25
L/min 21 18
%
upper level of the humidifier and

-20
Rate 40
-40 121/min8
21 12 1:2 0.2 10 3 5
the lowest part of the drawer or

plate of the cart is a minimum of

15 cm. I
Release the screw in front of the

rail mount to change the
position of the rail and tighten it,
when the correct position is found.
Place the active humidifier onto the rail and properly fix it there.
Fill humidifier chamber or use a Centiva/5
pre-filled humidifier chamber Bi-Level / ASB

15
MV-E
4.2Liter2
12
according to manufacturer’s
10
Vt-E
5
350 mL
Ppeak 21
Paw
14cmH2O
advice.
mbar
40
Pmin
3cmH2O
20
Flow O2-I 25
L/min 21 18
%
-20
Rate 40
-40 121/min8
21 12 1:2 0.2 10 3 5
Connect humidifier electrical

supply according to
manufacturer’s advice. I
Turn ON humidifier and verify

proper function.

5 Preparation
Connect an inspiratory tube from the right, front 22 mm

connector of the Centiva/5 to the inlet of the humidifier
chamber.
Connect the inspiratory tube from to the outlet of the humidifier
chamber to the y-piece.
Connect an expiratory tube from the left, front 22 mm

connector of the Centiva/5 and to a water trap.
Connect another expiratory Centiva/5
tube from the water trap to Bi-Level / ASB

15
MV-E 12
4.2Liter2
the y-piece.
10
Vt-E
5
350 mL
Ppeak 21
Paw
mbar
14cmH2O
40
Pmin
3cmH2O
20
Flow O2-I 25
L/min 21 18
%
-20
Rate 40
-40 121/min8
21 12 1:2 0.2 10 3 5
Water trap
CAUTION When using active humidifiers do not use HMEs between y-piece
and patient at the same time. This may result in increased
breathing resistance and risk to the patient .
Special notice Active humidifiers in general increase the resistance of the breathing
system. Care should be taken to keep the resistance as low as possible.

5 Preparation
5.6 Placing the device
5.6.1 Control panel For better visibility and easy handling the Centiva/5 control panel can
be adjusted to optimize the viewing angle.
To adjust the viewing angle, the
upper part of the control panel
can be moved forward or
backward.
The control panel can be detached from the main engine and mounted
a distance of up to 3 meters away from the main engine.
Centiva/5
15 MV-E 12
4.2Liter2
10 Vt-E
5
350 mL
Ppeak 21
Paw
mbar
14cmH2O
40
Pmin
3cmH2O
20
Flow O2-I 25
L/min 21 18
%
-20
Rate 40
-40 121/min8
21 12 1:2 0.2 10 3 5
For this application use the optional extension cable and mounting
accessories.
Positioning of control panel

• At the main engine with adjustable viewing angle
• At a wall rail mount (optional) with adjustable viewing angle
• At a bed mount (optional) with adjustable viewing angle

5 Preparation
To mount the Centiva/5 control panel away from the Centiva/5 main
engine , follow the instructions below.
Place the selected mounting bracket to the desired position.

Turn OFF the Centiva/5.
Move control panel to a full angled position.
Press both stainless steel buttons of the bracket mount together to

release the locking mechanism.
Move the control panel carefully to the front and up.
Disconnect the control panel from the main engine.
Place the control panel onto the selected bracket.

Connect control panel and control panel bracket and secure proper
seated connector.
Press both stainless steel buttons of the bracket mount together to
release the locking mechanism. Insert the bracket and release the two
buttons to activate the locking mechanism.
Reconnect the control panel and main engine using the extension
cable.
Turn ON the Centiva/5 and check for proper function by passing the
“power-up” test.
WARNING Do not disconnect the control panel during operation. This may
result in risk to the patient.

5 Preparation
5.6.2 Entire system Placement of the entire unit or main engine:

• On the trolley (optional)
• On other flat surfaces
• On a wall rail mount (optional)
• On an ICU cabinet
When placing the Centiva/5
ventilator on the optional Bi-Level / ASB

15
MV-E
4.2Liter2
12
trolley ensure that the feet

10 Vt-E
5
350 mL
Ppeak 21
match with the trolley’s

Paw
mbar
14cmH2O
40 Pmin
3cmH2O
20
receptacles.
Flow O2-I 25
L/min 21 18
%
-20
Rate 40
-40 121/min8
Ensure the locking

21 12 1:2 0.2 10 3 5
mechanism locks in,

when the device is
properly placed. I
To release the device pull O
the metal knob of locking

mechanism forward and
remove the device.
ot
ot
n
fo
fo
pi
g
g
ng
n
n
si
si
i
ck
ou
ou
Lo
H
CAUTION Always ensure proper seating of the system and activated locking
mechanism, when applicable.

5 Preparation
5.7 Turn ON and OFF
Turn ON The Centiva/5’s ON-OFF button is located on the lower right side of the
ventilator engine .
When supplied with line (mains) power (line switch on the rear should
always be turned ON) the ON-OFF button is illuminated by a green light
and the unit turns ON when the ON-OFF button is pressed.
If no mains supply is
present, or the mains
Centiva/5
MV-E 12
switch is off, the ON-OFF

15
5.2Liter2
10
Vt-E
350 mL
button is not illuminated.

5
Ppeak 21
Paw
cmH2O
14cmH2O
40
Pmin
3cmH2O
Pressing the ON-OFF
20
Flow O2-I 25
L/min 21 18
%
-20
button with no mains

Rate 40
-40 181/min8
21 12 1:2 0.2 10 3 5
supply activates the % 1/min sec cmH2O cmH2O cmH2O
internal back-up battery to

allow for service activities,
such as removing the I
expiratory valve assembly .

O
For safety reasons the
ON/OFF
Centiva/5 will not go into
normal operation when the main supply is missing.
Turn OFF The Centiva/5 can only be turned OFF when the patient is not being
ventilated and is disconnected (Status: System open ?).
In the non-ventilating Turn OFF device? Yes= Enter, No= any button
“System open ?” Centiva /5
mode, or in any other System test Rev. 2.1n
non-ventilating mode, System test OK. To start ventilation <Enter>
press and hold the ON-
Compliance 2.3 ml/cmH2O
OFF button for Resistance 0.8 cmH2O/L/s
approximately 3 secs.
Leakage 15 ml/min
Adult Pediatric
A message appears asking the user to either turn off the system by
confirming with the enter key (ComWheel) or returning to the current
status by pressing any other key.

5 Preparation
5.8 Self test
The Centiva/5 software includes self tests that determine if the

operating software is functioning properly and if the electronic and
pneumatic circuits are functional. The self tests include:
• Power-up test
• System test
• In-operation test
5.8.1 Power-up test The power-up test

starts automatically Centiva/5
when the system is System test Rev. x.nn
turned ON. The
Test active, wait for 5 secs
following screen is
displayed: Message box
The power-up test

takes at least 5 secs.
The test time counts
down on the screen.
During the power-up test, the ventilator checks the proper function of all
essential electronic components. If a malfunction is identified during
this power up test, the corresponding message appears in the message
box area. For details of
error messages refer to
section 8 “Alarms and Centiva/5
messages”. System test Rev. x.nn
After having passed the Complete system set up, seal y-piece
power-up test, the Start system test <Enter>
Centiva/5 prompts with

a short audible sound
and moves to the “Start Adult Pediatric
system test” screen:
Connect the breathing Bi-Level Tube : E 7.5 50%

Centiva/5
Adult
circuit to the system and 15
10
MV-E
5.2Liter2
Vt-E
12
seal the Y-piece by placing 5

350 mL
Ppeak 21
Paw
cmH2O
14cmH2O
the open end onto the 40

Pmin
3cmH2O
20
Flow O2-I 25
21 18
sealer on the exp. valve

L/min
%
-20
Rate 40
-40 181/min8
assembly.
21 12 1:2 0.2 10 3 5
O
Stopper

5 Preparation
5.8.2 System test Push the ComWheel to confirm the <Enter> command.
This starts the system

test. Centiva/5
System test
This system test takes Test active, wait for 35
at least 40 secs. The secs
test time counts down Message

box
on the screen.
Adult
During the system test, the system will check the proper function of all
pneumatic and electronic components together with the function of the
attached breathing circuit . If any malfunction is identified during this
system test, the corresponding message appears in the message box
area. For details of error messages refer to section 8 “Alarms and
messages”.
After having passed the

system test, the system Centiva/5
prompts the user to
open the Y-piece which
Open Y-piece
allows the testing of
inspiratory resistance.
Adult
Disconnect the Y-piece from the sealer.

The system will recognize that the Y-piece is open automatically and will
proceed with the system test.

5 Preparation
After measuring the

inspiratory resistance, Centiva /5
the Centiva/5 displays System test Rev. x.nn
the following screen: System test OK. To start ventilation <Enter>
The compliance and

Compliance 2.3 ml/mbar
Resistance 0.8 mbar/L/s
leakage values Leakage 15 ml/min
Nebulizer flow 7,0 l/min
represent the entire Exp. flow sensor data re-adjusted
breathing circuit and Adult
ventilator. This value is
used for the internal compliance compensation.
The resistance value represents the inspiratory resistance of the
breathing circuit and ventilator to the y-piece. This value is used for the
internal resistance compensation .
The nebulizer flow value represents the measured nebulizer flow of the
connected nebulizer. Incase no nebulizer was connected during system,
the last measured nebulizer flow is displayed with a note added (last
value).
In case the expiration flow sensor was readjusted during system test the
according message “Exp. flow sensor data re-adjusted” is displayed.
Values for compliance, resistance and leakage depend upon the

breathing circuit used.
Values for nebulizer flow depend upon the nebulizer used (if applicable)
For details to the nebulizer test refer to section 6. 3.10. “Nebulizer”.
Filters and HMEs may significantly increase the resistance values.
CAUTION Do not perform the system test with a filter or HME on the
breathing circuit. Inappropriate pressure and flow compensation
may result.
Other breathing circuit designs, such as co-axial systems, may increase
the measured resistance values.
CAUTION Always use breathing circuits with low inspiratory resistance.
5.8.3 In-operation test During operation the Centiva/5 continuously checks all safety relevant
functions and parameters. If a malfunction is identified, the system will
display alarms or messages on the screen. For details of error
messages refer to section 8 “ Alarms and messages”.

5 Preparation
5.9 Select the type of patient
The Centiva/5 allows for the pre-adjustment of ventilator settings and

alarm limits according to two different types of patients:
• Adult
• Pediatric
Prior to the system

tests the user can Centiva/5
select the desired
patient type on the System test
System test OK. To start ventilation
screen by pressing <Enter>
either of the soft keys Compliance 2.3 ml/cmH2O
Resistance 0.8 cmH2O/L/s
below the patient Leakage 15 ml/min
types.
Adult Pediatric
Activating the new patient type changes the color of the button in the
screen from gray to yellow to prompt the change.
This pre-selection is important to establish default settings in the

different ventilation modes. For details see section 6.1.2 “Default
ventilation values”.
The selected patient type is displayed during system test in the screen’s
lower left corner and during operation within the status information
area.
CAUTION The default settings provide a minimum ventilation for the

selected patient type, while the patient is connected and
prepared. After preparation and proper connection the settings
must be adjusted according to the patient’s needs.

5 Preparation
5.10 System test menu
After having successfully passed the power-up and/or the

system tests the system test menu can be activated by
pressing the menu button.
The system test menu

appears and allows for Centiva/5
the selection of certain
service functions. System Test
Selecting “Exit” closes
Complete system set up, seal Y-
piece
the system test menu Start system test by pressing
<Enter> Bypass system
without any activity. test expiration
Unlock
valve
Calibrate O2
sensor Exit
Adult
Service functions available in the system test menu are:

• Bypass system test
• Unlock expiration valve
• Calibrate O2 sensor
Bypass system test The required system test is bypassed with Bypass system test
this function. Unlock expiration valve
Calibrate O2 sensor
Exit
WARNING Use the system test bypass only in case of emergency.
CAUTION In this situation the system uses the compliance and resistance
data from the last system test for all internal compensations. If
the current breathing circuit differs significantly to the past circuit,
differences in ventilation parameters due to changes in the
compensation process are possible. This may result in risk to the
patient.
Starting the ventilator without having performed the system test will
result in a status display “no test” to remind the user that the system
was started without a system test and to perform the system test as
soon as possible.

5 Preparation
Unlock expiration valve This function releases the expiration valve Bypass system test
Unlock expiration valve
assembly. Calibrate O2 sensor
Exit
Releasing the
expiration valve is Centiva/5
necessary for cleaning
purposes only.
Expiration valve unlocked
Ready to be removed from device
After inserting the expiration

valve it will automatically
lock in place and the
system performs a power-
up test.
Releasing the expiratory
valve will work with
internal back-
up battery
power.
Locking
only works with line (mains) power supply.
O2 sensor calibration This function starts an automatic O2 sensor calibration procedure. For
details refer to section 9 “Maintenance”.

5 Preparation
5.11 Starting the ventilator
After having passed the

system test the Centiva /5
Centiva/5 will go to System test Rev. x.nn
normal operation when System test OK. To start ventilation <Enter>
the <Enter> button Compliance 2.3 ml/mbar

(ComWheel) is pressed. Resistance
Leakage
0.8 mbar/L/s
15 ml/min
Adult
Push the ComWheel to start ventilation.
The Centiva/5 defaults to the ventilation mode ”Bi-Level“ with the

ventilator settings and alarm limits set according to the selected patient
type.

6 Operation
In this section 6.1 Adjust ventilation modes 6-2

6.1.1 Select a ventilation mode 6-2
6.1.2 Default ventilation values 6-3
6.1.3 Changing ventilation modes 6-4
6.2 Adjust ventilation parameters 6-6
6.2.1 VCV 6-6
6.2.2 SIMV-VC 6-9
6.2.3 Bi-Level 6-12
6.2.4 Bi-Level/PSV 6-14
6.2.5 CPAP/PSV 6-17
6.2.5 CPAP/Apnea 6-19
6.3 Additional functions 6-21
6.3.1 Standby 6-22
6.3.2 ASR (Automatic Suction routine) 6-24
6.3.3 Parameter menu 6-27
6.3.4 Alarm limits 6-32
6.3.5 Alarm AUTOSET 6-38
6.3.6 ARC (Airway Resistance Compensation) 6-41
6.3.7 NEB (Nebulizer drug delivery) 6-44
6.3.9 NIV (Non Invasive Ventilation) 6-51
6.3.10 APD (Automatic Patient Detection) 6-53
6.3.11 OCV (Online O2 sensor Calibration) 6-54
6.3.12 Short cuts 6-55

6 Operation
6.1 Adjust ventilation modes
6.1.1 Select a ventilation The Centiva/5 uses the “Bi-Level” as the default mode.
mode The system uses default settings according to the selected patient type
to provide a minimum level of ventilation performance.
To change the default ventilation mode to another mode

open the main menu with the menu button.
Using the ComWheel select “Vent. Modes” to access

the ventilation modes menu.
Stand-by ON
ASR ON
Parameter menu
The “Vent. Modes” topic is highlighted. Alarm limits

Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
VCV
SIMV - VC
The ventilation modes menu appears. Bi-Level
CPAP/PSV
Make your selection with the ComWheel for the CPAP/Apnea
desired ventilation mode and confirm the selection Previous menu
by pushing the ComWheel. Exit
Adjust the ventilation parameter settings to the patient’s needs and set
the alarm limits accordingly.

6 Operation
6.1.2 Default ventilation When starting the Centiva/5 the system will provide default ventilator
values settings to enable easy preparation of the patient.
These settings are designed for the selected patient range to maintain a
minimum ventilation performance . The default ventilation mode is
“Bi-Level”.
Pediatric Parameter VCV SIMV-VC Bi-Level CPAP/PSV

FiO2 50 % 50 % 50 % 50 %
Rate 16 /min 16 /min 16 /min -
I:E 1:2 1:2 1:2 -
Vt 100 ml 100 ml - -
Ramp - - 0.2 sec -
Pinsp - - 7 cmH2O -
Plimit 20 cmH2O 20 cmH2O - -
PEEP Off Off Off Off
I-Flow 10 l/min 10 l/min - -
PS - 3 cmH2O 3 cmH2O 3 cmH2O
Adult Parameter VCV SIMV-VC Bi-Level CPAP/PSV

FiO2 50 % 50 % 50 % 50 %
Rate 10 /min 10 /min 10 /min -
I:E 1:2 1:2 1:2 -
Vt 500 ml 500 ml - -
Ramp - - 0.2 sec -
Pinsp - - 10 cmH2O -
Plimit 30 cmH2O 30 cmH2O - -
PEEP Off Off Off Off
I-Flow 30 l/min 30 l/min - -
PS - 5 cmH2O 5 cmH2O 5 cmH2O

6 Operation
6.1.3 Changing ventilation When changing from an active ventilation mode to another mode, the
modes Centiva/5 will transfer the settings for identical parameters (e.g. FiO2)
to the new mode.
For those non-transferable parameters algorithm are used to calculate
settings for the new ventilation mode based on measured data. These
algorithm are based on a calculation taking into account that the lung’s
compliance and resistance will not change significantly when changing
the mode.
VCV
Example: SIMV - VC
Change from Bi-Level mode Bi-Level

CPAP/PSV VCV
CPAP/Apnea SIMV - VC
Previous menu Bi-Level
to VCV (or SIMV-VC) mode: Exit CPAP/PSV
CPAP/Apnea
Previous menu
Exit
Parameter Bi-Level VCV

Settings Measured Settings
FiO2 50 % - 50%
Rate 10 /min - 10 /min
I:E 1:2 - 1:2
Ramp 0.2 sec - N/a
Pinsp 10 cmH2O - N/a
Vt N/a 350 ml ( C ) 330 ml
PEEP 3 cmH2O - 3 cmH2O
In Bi-Level the patient’s lung compliance is calculated and tidal volume

setting for the VCV or SIMV-VC mode is calculated according to
Vt set = Pinsp x C.
In case compliance calculation is not leading to stable data, the system
uses the lowest value for that mode.
The data used is stored in the Centiva/5 as long as the system is not
turned OFF. That provides automatic access to this data when
ventilation is restarted after standby. Whenever the system is turned
OFF and is turned ON again, the default settings are used.
CAUTION Ensure all parameter settings and alarm limits are set according
to the patient’s situation.

6 Operation
Example: VCV
Change from VCV (or SIMV-VC) mode SIMV - VC
Bi-Level
CPAP/PSV
CPAP/Apnea
Previous menu
Exit
to Bi-Level mode: VCV

SIMV - VC
Bi-Level
CPAP/PSV
CPAP/Apnea
Previous menu
Exit
Parameter VCV Bi-Level

Settings Measured Settings
FiO2 50 % - 50%
Rate 10 /min - 10 /min
I:E 1:2 - 1:2
Ramp N/a - Default
Pinsp N/a (C) 10 cmH2O
Vt 350 ml - N/a
PEEP 3 cmH2O - 3 cmH2O
In VCV or SIMV-VC the patient’s lung compliance is calculated and

inspiratory pressure setting for the Bi-Level mode is calculated
according to
Pinsp = Vt / C.
In case compliance calculation is not leading to stable data, the system
uses the lowest values for that mode.
The data used is stored in the Centiva/5 as long as the system is not
turned OFF. That provides automatic access to this data when
ventilation is restarted after standby. Whenever the system is turned
OFF and is turned ON again, the default settings are used.

6 Operation
6.2 Adjust ventilation parameter
6.2.1 VCV Volume Controlled Ventilation.

This mandatory ventilation mode provides a constant minute volume to
a patient, that has limited spontaneous breathing capabilities.
Paw
P max
P limit
PEEP
0 t
Spontaneous breathing
Insp.
Pause
T insp T exp
60/rate
Flow
I-Flow
0 t
The desired minute volume is determined by the set tidal volume (Vt)
and the set rate (rate).
The pressure and flow waveforms are influenced by the timing for
inspiratory and expiratory times (I:E) and by the inspiratory flow (I-Flow).
The system automatically provides an inspiratory pause depending on
timing and flow. The higher the I-Flow the longer the plateau time.
Although this is a mandatory mode, the system allows patient’s

spontaneous breathing during the expiration time and therefore, allows
the patient to increase the total minute volume beyond the set
mandatory.

6 Operation
Use the soft keys to adjust the ventilation settings, described above
according to the patient’s needs
Fi O2 Rate I:E Vt Plimit PEEP I-Flow
50
%
10
1/Min
1:2.0 110 mL
30
cmH2O
OFF
cmH2O
6.6
L/Min
I-flow 10.0 L/m

Additional adjustments for
PS ramp 0.20 s
• Byflow
Trigg. 3.0 L/m
can be set in the parameter menu. ByFlow 3.0 L/m
Time window 60%
PS endflow 25%
Buzzer 100%
Previous menu
Exit
Leakage compensation A leak can occur when ventilating patients. To compensate for such
leakage, the Centiva/5 is equipped with an automatic leakage
compensation.
This leakage compensation is always active and compensates for
temporary as well as permanent leaks.
The compensation covers a maximum leak of up to 50% of the desired
tidal volume.
For more details refer to section “NIV” in this chapter.
CAUTION Always set the leakage alarm at an appropriate level to ensure

immediate notification in the event a leak were to occur.

6 Operation
Pressure limited Changes in a patient’s lung compliance or resistance can alter the peak
ventilation pressure at given settings.
When in the VCV mode, the Plimit setting provides the ability to perform
Pressure Limited Ventilation (PLV).
Paw
Volume not delivered

P max
Pressure limited
P limit
PEEP
0 t
When Plimit is reached the flow is decelerated to limit the pressure to the
set Plimit level. A low priority message “Plimit reached” will appear on the
screen.
When pressure limitation causes a tidal volume of less than 80% of the
set tidal volume to be delivered an alarm will indicate this with the “Vt
not delivered” message.
Beyond the “Plimit” level there is a second pressure safety barrier “Pmax“
for additional safety. The Pmax is automatically set to 10 cmH2O over the
Plimit (default). When the Pmax level is reached all inspiratory flow is
stopped and the over pressure release valve is activated, reducing the
pressure to the PEEP level.
The Pmax safety pressure level can be adjusted manually in the alarm
limits menu.

6 Operation
6.2.2 SIMV-VC Synchronized Intermittent Mandatory Ventilation – Volume Constant

This synchronized mandatory ventilation mode provides a constant
mandatory minute volume and supports spontaneous breathing with
pressure support ventilation (PSV) for patients with limited
spontaneous breathing capability or to intentionally reduce the
mandatory support.
Paw
P max
Spontaneous breathing
without pressure support
P limit
Short Long
Ramp Ramp
P ASB
PEEP
0 t
Trigg. window Spontaneous breathing

with ASB pressure support
T insp T exp
60/rate
Flow
I-Flow
0 t
Mandatory parameters The desired mandatory minute volume is determined by the set tidal
volume (Vt) and the set rate (rate).
The pressure and flow waveforms are influenced by the timing for
inspiratory and expiratory times (I:E) and by the inspiratory flow (I-Flow).
The system automatically provides an inspiratory pause depending on
timing and flow. The higher the I-Flow the longer the pause (plateau)
time.

6 Operation
Trigger parameters To synchronize the mandatory ventilation with the spontaneous

breathing activity of the patient, the Centiva/5 uses a flow trigger that
detects the patient’s inspiratory effort. The sensitivity of the flow trigger
(Trigg.) can be adjusted to match the patient’s needs. The lower the flow
value the more sensitive the system reacts. Self triggering can occur at
low trigger flow settings.
The detected flow trigger needs to occur within the trigger time window
(time window) to start a synchronized mandatory breath.
PSV parameter Pressure support ventilation is a pressure support (PS) function that will
increase the tidal volume or decrease the work of breathing)of a
spontaneous breathing patient. When a pressure supported breath is
initiated the ventilator delivers the required flow to increase the
pressure to the set PS pressure above the PEEP level. The pressure
support breath ends when the flow to the patient decreases to the set
PS end flow measured in % of the peak PSV flow. 25% is the default
setting.
The rise time between the PEEP level and the PS pressure level can be
modified by the PS- ramp time (ramp). The shorter the ramp time the
higher the initial PS flow.
The Centiva/5 allows spontaneous breathing on the PEEP pressure
level if the PSV function is turned off (PS set to 0 cmH2O).
Settings Use the soft keys to adjust the ventilation settings according to the
patient’s needs.
Fi O2 Rate I:E Vt Plimit PEEP PS
50%
10
1/Min
1:2.0 110 mL
30
cmH2O
OFF
cmH2O
10
cmH2O
Additional adjustments for I-flow 10.0 L/m

• Inspiratory flow (I-Flow) PS ramp 0.20 s
• PS ramp time (PS ramp) Trigg. 3.0 L/m

ByFlow 3.0 L/m
• Trigger flow sensitivity (Trigg)
Time window 60%
• Byflow (Byflow) PS endflow 25%
• Trigger time window (time window) Buzzer 100%
• PS end flow (PS endflow) Previous menu
Exit
can be set in the parameter menu.

6 Operation
compensation.
The compensation covers a maximum leak of up to 50% of the desired
tidal volume.

ARC The Airway Resistance Compensation (ARC) can be activated in the

SIMV-VC mode .
ARC compensates for the inspiratory and expiratory resistance of the
patient’s artificial airway.
For more details refer to section “ARC” in this chapter.
Pressure limited In the SIMV-VC mode the Plimit setting also allows for Pressure Limited
ventilation Ventilation (PLV).
Paw
Volume not delivered

P max
Pressure limited
P limit
PEEP
0 t
This mode is identical with the PLV mode in VCV mode.

For more details refer to the section ”PLV” in the “VCV” section in this
chapter.

6 Operation
6.2.3 Bi-Level Bi – Level

Without spontaneous breathing This synchronized, time controlled, pressure cycled ventilation mode
provides a CPAP with two pressure levels. The change between these
two pressure levels provides a mandatory minute volume to patients
with limited spontaneous breathing capability.
Paw
P max
short long
ramp ramp
P insp
PEEP
0 t
T insp T exp
ramp time
60/rate
Without spontaneous breathing
Flow
The desired minute volume is determined by the set pressure difference

between the upper and lower CPAP level (Pinsp) and the set rate (rate)
and is dependent on the patient’s lung compliance and resistance.
The pressure and flow waveform is influenced by the timing for the
inspiratory and expiratory times (I:E) and the ramp time (ramp) between
the lower und upper pressure level.
The base pressure level is adjusted with the positive end expiratory
pressure (PEEP) setting.
Although this is a mandatory mode, the system allows spontaneous

breathing during the inspiration and expiration period which allows the
patient to increase their total minute volume beyond the set mandatory
minute volume.

6 Operation
according to the patient’s needs.
50
%
10
1/Min
1:2.0 0.20 Sec.
10
cmH2O
OFF
cmH2O
0
cmH2O
• Byflow (Byflow) PS ramp 0.20 s

Trigg. 3.0 L/m
ByFlow 3.0 L/m
Time window 60%
PS endflow 25%
Buzzer 100%
Previous menu
Exit
compensation.


6 Operation
6.2.4 Bi-Level Bi – Level

With spontaneous breathing This synchronized, time controlled, pressure cycled ventilation mode
provides a CPAP with two pressure levels. The change between the two
pressure levels provides a mandatory minute volume and supports
spontaneous breathing activities with PSV for patients with limited
spontaneous breathing capability or to intentionally reduce the
mandatory support.
Paw
P max
PS
P insp
PEEP
0 t
Spontaneous breathing time window Spontaneous breathing
without pressure support with pressure support
60/rate
with spontaneous
breathing
Flow
Mandatory parameters The mandatory parameters are identical to the previous section
“Bi-Level without spontaneous breathing”.
The desired minute volume is determined by the set pressure difference
between the upper and lower CPAP level (Pinsp) and the set rate (rate)
and is dependent on the patient’s lung compliance and resistance.
The pressure and flow waveform is influenced by the timing for the
inspiratory and expiratory times (I:E) and the ramp time (ramp) between
the lower und upper pressure level.

6 Operation
Trigger parameters To synchronize the mandatory ventilation with the spontaneous

breathing activity of the patient, the Centiva/5 uses a flow trigger to
detect the patient’s inspiratory effort. The sensitivity of the flow trigger
(Trigg.) can be adjusted to match the patient’s needs. The lower the flow
trigger value the more sensitive the system becomes. Auto-triggering
can occur at low trigger flow settings.
The detected flow trigger needs to match with the trigger time
expectation window (time window) to start a synchronized mandatory
breath.
increase the tidal volume or decrease the work of breathing of a
setting.
Settings Use the soft keys to adjust the ventilation settings, described above,
50
%
10
1/Min
1:2.0 0.20 Sec.
10
cmH2O
OFF
cmH2O
10
cmH2O
• PS ramp time (PS ramp) PS ramp 0.20 s

Trigg. 3.0 L/m
ByFlow 3.0 L/m
• Byflow (Byflow) Time window 60%
• Trigger time window (time window) PS endflow 25%
• PS end flow (PS endflow) Buzzer 100%

Previous menu
Exit

6 Operation
compensation.


Bi-Level mode .
patients artificial airway.
For more details refer to section “ARC” in this chapter.

6 Operation
6.2.5 CPAP/PSV Continuous Positive Airway Pressure / Pressure Support Ventilation

This ventilation mode provides a set continuous positive airway
pressure for a spontaneous breathing patient, with or without a set
pressure support level. This mode requires a patient’s stable
spontaneous breathing activity.
Paw
short long
ramp ramp
P ASB
PEEP
0 t
ramp time
Flow
ASB endflow
25 %
t
Trigger parameters To detect the inspiration effort of a patient’s spontaneous breathing

activity the Centiva/5 uses a flow trigger. The sensitivity of the flow
trigger (Trigg.) can be adjusted to match the patient’s needs. The lower
the flow trigger value the more sensitive the system becomes . Auto-
triggering can occur at low trigger flow settings.

6 Operation
increase the tidal volume or decrease the work of breathing of a
setting.
Settings Use the soft keys to adjust the ventilation settings, described above
Fi O2 Ramp PEEP PS
50
%
0.20 Sec.
OFF
cmH2O
5
cmH2O

• Trigger flow sensitivity (Trigg) PS ramp 0.20 s
• Byflow (Byflow) Trigg. 3.0 L/m
• PS end flow (PS endflow) ByFlow 3.0 L/m

Time window 60%
PS endflow 25%
Buzzer 100%
Previous menu
Exit

CPAP/PSV mode.
patient’s artificial airway.
For more details refer to section “ARC” in this chapter

6 Operation
6.2.6 CPAP/Apnea Continuous Positive Airway Pressure with APNEA mandatory back-up
ventilation.
This ventilation mode provides a set continuous positive airway

pressure for a spontaneous breathing patient, with or without a set
pressure support level. This mode requires a patient’s stable
spontaneous breathing activity. For more details refer to the mode
“CPAP/PSV” in this section.
In case the patient experiences an apneic episode while in this mode

this ventilator will provide a back-up mode of ventilation using the
• Bi – Level.
This synchronized, time controlled, pressure cycled ventilation mode
provides a CPAP with two pressure levels. This change between the two
pressure levels provides a mandatory minute volume and supports
spontaneous breathing activities with PSV for patients with limited
spontaneous breathing capability. For more details refer to the mode
“Bi-Level” in this section.
Setting CPAP/PSV When starting this mode “CPAP/PSV” is activated with the
corresponding soft keys highlighted.
50
%
10
1/Min
1:2.0 0.20 Sec.
10
cmH2O
OFF
cmH2O
10
cmH2O

I-flow 10.0 L/m
PS ramp 0.20 s
• Byflow (Byflow) Trigg. 3.0 L/m
• PS end flow (PS endflow) ByFlow 3.0 L/m
can be set in the parameter menu. Time window 60%

PS endflow 25%
Buzzer 100%
Previous menu
Exit

6 Operation
Setting the Back-up When Apnea is detected, the system switches automatically to the
ventilation mode ventilation mode “Bi-Level”. The settings of this mode are displayed ,
but the soft keys are grayed to indicate that the settings can be set but
are not active until the back up ventilation mode is activated.
50
%
10
1/Min
1:2.0 0.20 Sec.
10
cmH2O
OFF
cmH2O
10
cmH2O

I-flow 10.0 L/m
• PS ramp time (PS ramp)
PS ramp 0.20 s
• Trigger flow sensitivity (Trigg) Trigg. 3.0 L/m
• Byflow (Byflow) ByFlow 3.0 L/m
• Trigger time window (Time window) Time window 60%

PS endflow 25%
• PS end flow (PS endflow)
Buzzer 100%
can be set in the parameter menu. Previous menu
Exit
If the patient’s spontaneous breathing activity resumes the ventilator

remains in the ventilation mode “Bi-Level”. The system does not
automatically return to the ventilation mode “CPAP/PSV”.
To switch back to the initial mode requires the operator to re-select this
ventilation mode from the ventilation menu.

6 Operation
6.3 Additional functions
The Centiva/5 ventilator offers additional functions to support the

operation of the ventilator and to allow fine-tuning for particular needs.
The following functions are available in the main menu:
• Stand-by Stand-by ON
• ASR (Automatic Suction Routine) ASR ON

Parameter menu
• Parameter menu
Alarm limits
• Alarm limits Alarm AUTOSET
• Alarm AUTOSET Vent. modes
• ARC (Airway Resistance Compensation) ARC

Nebulizer ON
• Nebulizer
System test
• System test Exit
These functions will be described in detail in the order they appear in

the main menu.
The Centiva/5 provides other additional functions that are permanently

activated.
• NIV (Non-Invasive Ventilation)

• APD (Automatic Patient Detection)
These functions are described in this chapter.

6 Operation
6.3.1 Stand-by The standby function allows for the temporary interruption of the
Centiva/5 ventilator without alarming. All patient related settings are
saved and available upon reconnecting the patient to the ventilator.
To activate the standby function the user must disconnect the patient
from the system and wait for the “System open?” message on the
screen.
Select the function “Stand-by ON” by rotating the

ComWheel.
Stand-by ON
Special notice This function is only accessible when a patient is ASR ON
disconnected from the ventilator. Parameter menu

Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
Push the ComWheel to confirm the selection.
Notice the change in the menu from “Standby ON” Stand-by OFF
to “Stand-by OFF”.
ASR ON
The status line in the screen indicates the “Stand- Parameter menu
by” mode is active. Alarm limits
Ventilation is stopped and all alarms are silenced. Alarm AUTOSET
All ventilation settings are stored. Vent. modes
ARC
Nebulizer ON
System test
Close the main menu either with “Exit” or the menu
Exit
will close automatically after 30 secs.

6 Operation
To turn OFF the stand-by mode and to return to the former ventilation
mode reconnect the patient to the Centiva/5.
When the reconnection is detected by the APD function, the stand-by

function automatically is turned off and the Centiva/5 proceeds with
ventilating the patient with the stored parameters .
The Automatic Patient Detection (APD) has a delay of 15 secs after

turning ON the stand-by mode before becoming active to reduce false
triggering of the APD function.
To manually turn OFF the stand-by mode and ventilate using current
settings :
• open the main menu with the menu button
• select the “Stand-by OFF” with the ComWheel
• confirm the selection
• close the menu with “Exit”.

6 Operation
6.3.2 ASR (Automatic To perform bronchial suction the user needs access to the patient’s
Suction Routine) tube.
Using a breathing circuit with a bronchial suction access port the user
can perform this therapy while in the ventilation mode .
To gain access to the tube on most breathing circuits the patient needs
to be disconnected from the ventilator.
The Centiva/5 offers an Automatic Suction Routine (ASR) that provides

the following sequence:
• Pre-suction oxygenation phase for up to 2 minutes
• Stand-by suction phase for up to 2 minutes with silenced alarms
• Post-suction oxygenation phase for up to 2 minutes.
ASR can be activated in all ventilation modes via the main menu.
To activate the ASR functions open the main menu by

pushing the menu button.
Select the function “ASR ON” by rotating the ComWheel.
Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit

6 Operation
Notice the change in the menu from “ASR ON” to Stand-by ON
“ASR OFF”. ASR OFF
The first phase of ASR starts immediately. Parameter menu

Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
Pre-Oxygenation phase The status line in the screen shows “Pre-Ox 1:59” System test
to indicate the start of the pre-oxygenation phase Exit
and to show the remaining time in this phase.
The soft key for the FiO2 setting changes from the
previous setting to 100 Vol %. The soft key color
changes from yellow to red to indicate that this is a
temporary change during the ASR procedure.
This FiO2 setting for the pre-oxygenation of 100 Vol % can be adjusted
to any desired FiO2 by the user.
Suction phase After 2 minutes the pre-oxygenation phase ends and the suction phase
starts. The status line in the screen shows “Suct 1:59” to indicate the
start of the suction phase and to show the remaining time in this phase.
The ventilator is stopped and the pressure is relieved to zero to allow
hygienic opening of the patient’s tube connection.
The screen shows the message “System open?”.
All alarms are silenced, but the Centiva/5 gives a short audible signal
to indicate the start of the suction phase. This audible signal is
repeated every 5 secs to remind the operator ventilation is not active.
Within 15 secs the patient needs to be disconnected from the

ventilator. If the APD does not recognize a patient disconnect within this
15 second window the suction phase will be terminated and the
ventilator will go to the post-oxygenation phase.
If after 2 minutes the APD does not recognizes a reconnection of the

patient the Centiva/5 starts the Apnea Alarm.

6 Operation
Post-Oxygenation phase The status line in the screen shows “Post-Ox 1:59” to indicate the start
of the post-oxygenation phase and to show the remaining time in this
phase.
The ventilator starts back in the set mode with the previous ventilation
pattern and settings. PEEP pressure will build up again. All alarms are
activated .
The soft key for FiO2 setting is still set to the value of the
pre-oxygenation phase. The color of the soft key is still
red to indicate this temporary change by the ASR
procedure.
This FiO2 default setting for the post-oxygenation of 100 Vol % can be
adjusted to any desired FiO2 by the user.
At the end of the 2 minute post-oxygenation phase the FiO2 setting

returns automatically to the setting prior to the start of the ASR
procedure. The ASR procedure turns off automatically.
WARNING Ensure sufficient patient oxygenation if the FiO2 pre and post
suction concentration is changed from 100 Vol % to any other
value.
ASR can be activated by a short cut. For more details refer to section
“short cuts” in this chapter.

6 Operation
6.3.3 Parameter menu Frequently used settings for the different ventilation modes are
accessible via the soft keys on the screen. Centiva/5 offers additional
setting options. To keep the interface easy to use these other settings
are accessible in the parameter menu.
The parameter menu provides access to certain settings depending on
the current ventilation mode. For details refer to the “Adjust ventilation
parameters” in this section.
To access the parameter menu open the main menu by pushing

the menu button.
Select the function “Parameter menu” by rotating the

ComWheel.
Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
The parameter menu is accessible.
I-flow 10.0 L/m

Close the parameter menu and main menu either PS ramp 0.20 s
with “Exit” or let the menu close automatically after Trigg. 3.0 L/m
30 secs. ByFlow 3.0 L/m
Time window 60%
PS endflow 25%
Buzzer 100%
Previous menu
Exit

6 Operation
I-flow Available in the ventilation mode SIMV-VC. I-flow 10.0 L/m
This allows the setting of the inspiratory flow in the PS ramp 0.20 s
range of 2 to 99.9 L/min, depending on the timing Trigg. 3.0 L/m
settings of the mode. ByFlow 3.0 L/m

Time window 60%
This setting is identical to the I-flow soft key setting
in the ventilation mode “VCV”.
PS endflow 25%
Buzzer 100%
Previous menu
Exit
PS ramp Available in the ventilation modes: SIMV-VC, I-flow 10.0 L/m
Bi-Level, CPAP/PSV and CPAP/Apnea. PS ramp 0.20 s

Trigg. 3.0 L/m
This setting adjusts the rate the pressure increases
ByFlow 3.0 L/m
from the PEEP pressure to the PS pressure in the
range of 0.1 to 0.5 secs. This setting is similar to
Time window 60%
the Bi-Level ramp soft key setting.

PS endflow 25%
Buzzer 100%
The default setting is 0.2 secs. Previous menu
Exit
Trigg. Available in the following ventilation modes: SIMV- I-flow 10.0 L/m
VC, Bi-Level, CPAP/PSV and CPAP/Apnea. PS ramp 0.20 s

Trigg. 3.0 L/m
This allows the setting of the flow trigger in the
ByFlow 3.0 L/m
range of 0.5 to 20 L/min. The flow trigger value is
the amount of flow the patient needs to remove
Time window 60%
from the breathing circuit by their inspiratory effort PS endflow 25%
to trigger the ventilator. Buzzer 100%

Previous menu
The default setting is 3.0 L/min.
Exit
Byflow Available in the ventilation modes: VCV, SIMV-VC,

I-flow 10.0 L/m
Bi-Level, CPAP/PSV and CPAP/Apnea.
PS ramp 0.20 s
The setting of the Byflow is from 3.0 to 30 L/min. Trigg. 3.0 L/m
The Byflow permanently flows through the ByFlow 3.0 L/m
breathing circuit providing a “flow reservoir” for a Time window 60%
spontaneous breathing patient. Increasing the PS endflow 25%
Byflow increases the flow reservoir, but also
Buzzer 100%
increases the pressure drop within the breathing
Previous menu
circuit. The default setting is 3.0 L/min.
Exit

6 Operation
Time window Available in the ventilation modes: SIMV-VC, I-flow 10.0 L/m
Bi-Level and CPAP/Apnea. PS ramp 0.20 s
This is a trigger window that provides the time Trigg. 3.0 L/m
when a patient’s trigger efforts will synchronize ByFlow 3.0 L/m
with the mandatory or PSV ventilation. This time Time window 60%
window is defined in % of the maximum expiration PS endflow 25%

time with a range of 20 % to 90 %. Buzzer 100%
The default setting is 60%. Previous menu

Exit
The drawing below shows the time window as a % of the expiration time
for a setting of 50%.
Paw
P insp
PEEP
0 t
Time
window = 50%
Expiration
time = 100%

6 Operation
PS endflow Available in the ventilation modes: SIMV-VC, I-flow 10.0 L/m
This is the setting for the flow criteria to end the Trigg. 3.0 L/m
pressure supported breath. ByFlow 3.0 L/m

Time window 60%
The flow criteria is defined as a % of the peak flow
measured within a specific PSV breath in the range
PS endflow 25%
of 10 % to 60 %.
Buzzer 100%
Previous menu
The PS endflow allows for fine adjustment of the
Exit
pressure support to a patient’s lung dynamic.
The default setting is 25%.
The drawing below shows the PS endflow as a % of the PSV peak flow
for a setting of 10% and 60%.
Paw
PS
PEEP
t
Flo
w
Peak flow
End of support
60%
End of support
10%
t
PS PS
Endflow = 10% Endflow = 60%

6 Operation
Buzzer Available in all ventilation modes: VCV, SIMV-VC, I-flow 10.0 L/m
This is the volume setting for the alarm speakers in Trigg. 3.0 L/m
the range of 20% to 100%. ByFlow 3.0 L/m
The default setting is 100%. Time window 60%

PS endflow 25%
Buzzer 100%
Previous menu
Exit
Previous menu This function leads back to the previous (main) I-flow 10.0 L/m
menu. PS ramp 0.20 s
Trigg. 3.0 L/m
ByFlow 3.0 L/m
Time window 60%
PS endflow 25%
Buzzer 100%
Previous menu
Exit
Exit This function closes the parameter menu. I-flow 10.0 L/m
PS ramp 0.20 s
Without any activity (button or the ComWheel) all Trigg. 3.0 L/m
menus close automatically after 30 secs. ByFlow 3.0 L/m

Time window 60%
PS endflow 25%
Buzzer 100%
Previous menu
Exit

6 Operation
6.3.4 Alarm limits Adequate monitoring of a patient’s breathing and the device function is
supported by the internal monitoring capabilities of the Centiva/5.
Alarm limits must be set appropriately according to the patient’s
condition and the set ventilator parameter ranges.
Alarm limits must represent a safe area for the patient. When the
current value of a parameter increases beyond the upper limit or
decreases below the lower limit the alarm will activate.
Depending on the parameter and the level of priority, the Centiva/5
prompts with either a high or low priority alarm. For details about alarm
modalities and messages refer to section 8 “Alarms and messages”.
A high priority audible alarm can be silenced for 2 minutes by
pushing the alarm silence button. A clock indicating the
alarm silence time starts simultaneously on the screen.
New alarms occurring while the alarm silence is activated will restart the
audible alarm.
When a high priority alarm condition no longer exists, the alarm
message turns from red to yellow and the flashing red alarm light and
audible alarm are turned off.
The yellow alarm message stays on the screen until the alarm silence
button is pressed again. This allows for the monitoring of alarms that
have occurred and have reset.
When several alarms occur concurrently, the alarm messages are
displayed in order of appearance.
Depending on the selected type of patient the Centive/5 defaults to set

alarm limits to enable immediate monitoring capability.
After the patient has been placed on the ventilator and the settings are
stable the alarm limits need to be reset to a level that is appropriate for
the patient’s condition.

6 Operation
The alarm limits are shown in the monitored MV-E 12.0

parameter area in red figures. Upper red figure
represents the upper alarm limit, lower figure
the lower alarm limit. The following alarm
3.0 2.5 Liter
TV-E
limits exist:
• Upper alarm limit for expiratory minute
volume MV-E
361 mL
Ppeak
21
• Lower alarm limit for expiratory minute
volume MV- E 14 cmH2O
• Maximum airway pressure (Pmax) Pmin

• Upper alarm limit for inspiratory O2
concentration
1 cmH2O
O2-I
26
• Lower alarm limit for inspiratory O2
concentration 21 18 %
• Upper alarm limit for measured total rate Rate

40
• Lower alarm limit for measured total rate.
10 8 1/min
Alarm limits when starting Selecting a patient default level pre-adjusts the ventilator settings and
sets the alarm limits. When ventilator settings are adjusted to the
patient’s needs , alarm limits need to be set accordingly.
Alarm limits for FiO2 The user does NOT make the upper and lower alarm limits for the
inspiratory oxygen concentration. The alarm limits for the measured
inspiratory O2 concentration are set automatically based on the set
concentration .
Set FiO2 Lower alarm limit Upper alarm limit

21 to 50 Vol% (18 or Set FiO2 –5 )Vol% Set FiO2 + 5 Vol%
51 to 60 Vol% Set FiO2 – 6 Vol% Set FiO2 + 6 Vol%
100 Vol% Set FiO2 – 10 Vol% Set FiO2 + 10 Vol%

6 Operation
Set alarm limits To access the alarm limit menus open the main menu by
Select the function “Alarm limits” by rotating the

ComWheel.
Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
The alarm limit menu opens.
Close the alarm limit menu and the main menu by MV max 1.7 L
either selecting “Exit” or let the menus close MV min 0.5 L
automatically after 30 secs. Leakage 25%
Pmax 40cmH2O
Apn.del. 20 Sec
Rate max 40/Min
Rate min 8/Min
Previous menu
Exit

6 Operation
MV max The upper limit for minute volume has an MV max 1.7 L
adjustable range from 99 to 0.5 L/min. Measured MV min 0.5 L
minute volume exceeding the adjusted maximum Leakage 25%
minute volume “MV max” triggers the alarm. The Pmax 40cmH2O
alarm is reset when the measured minute volume Apn.del. 20 Sec
falls below the adjusted “MV max”. “MV max” Rate max 40/Min
cannot be set below “MV min”. 8/Min
Rate min
The default setting is 12 L/Min (Adult) and 5 L/min Previous menu
(Pediatric) Exit
MV min The lower limit for minute volume has an MV max 1.7 L
adjustable range from 0.5 to 99 L/min. Measured MV min 0.5 L
minute volume falling below the adjusted Leakage 25%
minimum minute volume “MV min” triggers the Pmax 40cmH2O
alarm. The alarm is reset when the measured Apn.del. 20 Sec
minute volume exceeds the adjusted “MV min”. Rate max 40/Min
“MV min” cannot be set above “MV max”. Rate min 8/Min
The default setting is 2.5 L/min (Adult) and 1.2 Previous menu
L/min (Pediatric) Exit
Leakage The upper limit for leakage is measured as a % MV max 1.7 L

difference between the inspiratory and expiratory MV min 0.5 L
flow with an adjustable range from 5 to 95% of the Leakage 25%
inspiratory flow. Measured leakage exceeding the Pmax 40cmH2O
adjusted maximum “leakage” triggers the alarm. Apn.del. 20 Sec
The alarm is reset when the measured leak falls Rate max 40/Min
below the adjusted maximum “leakage” limit. Rate min 8/Min
The default setting is 25 % leak. Previous menu
Exit
P max The upper limit for the absolute airway pressure MV max 1.7 L
has an adjustable range of 21 to 70 cmH2O. The MV min 0.5 L
Pmax alarm limit follows the highest pressure Leakage 25%
setting, according to the set ventilation mode, with Pmax 40cmH2O
the set difference (set diff.): Apn.del. 20 Sec
Pmax = Plimit + set diff. in VCV, SIMV-VC Rate max 40/Min
Pmax = Pinsp + set diff. in Bi-Level Rate min 8/Min
Pmax = PS + set diff. in CPAP/PSV, CPAP/Apnea

Previous menu
Exit
The default set difference is 10 cmH2O.

6 Operation
P max Measured airway pressure exceeding the adjusted

MV max 1.7 L
Continued maximum airway pressure “P max” triggers an
MV min 0.5 L
alarm, stops the inspiratory flow, switches to the
expiratory phase and opens the active over
Leakage 25%
pressure relief valve. The alarm is reset when the Pmax 40cmH2O
measured airway pressure falls below the adjusted Apn.del. 20 Sec
“Pmax”. Rate max 40/Min

Rate min 8/Min
Previous menu
Exit
Apnea del. The upper limit for the apnea time (no breathing
MV max 1.7 L
activity) has an adjustable range from 10 to 60
MV min 0.5 L
secs. Measured time without any breathing activity
exceeding the maximum apnea time triggers an
Leakage 25%
alarm. An indicator showing the total time without Pmax 40cmH2O
breathing activity is displayed . The alarm resets Apn.del. 20 Sec
when breathing activity is measured. Rate max 40/Min

Rate min 8/Min
The default setting is 20 secs.
Previous menu
Exit
Rate max The upper limit for the breathing rate is adjustable MV max 1.7 L
from 200 to 4 /min. Measured rates exceeding the MV min 0.5 L
adjusted maximum rate “Rate max” triggers the Leakage 25%
alarm. The alarm resets when the measured rate Pmax 40cmH2O
falls below the adjusted “Rate max”. “Rate max” Apn.del. 20 Sec
cannot be set below “Rate min”. Rate max 40/Min
The default setting is 40/Min (Adult) and 60/min Rate min 8/Min
(Pediatric). Previous menu
Exit
Rate min The lower limit for the breathing rate has an MV max 1.7 L
adjustable range from 4 to 200 /min. A measured MV min 0.5 L
rate falling below the adjusted minimum rate “Rate Leakage 25%
min” triggers the alarm. The alarm resets when the Pmax 40cmH2O
measured rate exceeds the adjusted “Rate min”. Apn.del. 20 Sec
“Rate min” cannot be set above the “Rate max”. Rate max 40/Min
The default setting is 8/min (Adult) and 14/min Rate min 8/Min
(Pediatric). Previous menu
Exit

6 Operation
Previous menu The function leads back to the previous (main) MV max 1.7 L
menu.
MV min 0.5 L
Leakage 25%
Pmax 40cmH2O
Apn.del. 20 Sec
Rate max 40/Min
Rate min 8/Min
Previous menu
Exit
Exit The function closes the parameter menu. MV max 1.7 L

MV min 0.5 L
Without any activity (button or the ComWheel) all Leakage 25%
menus close automatically after 30 secs. Pmax 40cmH2O

Apn.del. 20 Sec
Rate max 40/Min
Rate min 8/Min
Previous menu
Exit

6 Operation
6.3.5 Alarm AUTOSET For those cases when the patient’s “clinical picture” matches the
measured data Centiva/5 offers a fast way to set all alarm limits
according to the “clinical picture“ using the AUTOSET function.
AUTOSET establishes the alarm limits according to the measured
parameters. Whenever the ventilator parameters are changed new
alarm limits can be set to match the “clinical picture” by activating
AUTOSET.
To access the alarm AUTOSET function open the main menu

by pushing the menu button.
Select the function “Alarm AUTOSET” by rotating the

ComWheel.
Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
The alarm AUTOSET function is activated and sets the alarm limits
according to the measured patient data, valid at the moment of
activation.
Close the main menu either with “Exit” or let the menus close
automatically after 30 secs.

6 Operation
MV max (AUTOSET) Upper limit for minute volume is set to the measured patient minute
volume + 150%.
Measured minute volume exceeding the adjusted maximum minute
volume “MV max” triggers the alarm. The alarm is reset when measured
minute volume falls below the “MV max” setting.
MV min (AUTOSET) Lower limit for minute volume is set to the measured patient minute
volume – 50%.
Measured minute volume falling below the adjusted minimum minute
volume “MV min” triggers the alarm. The alarm is reset when measured
minute volume exceeds the “MV min” setting.
P max (AUTOSET) Upper limit for absolute airway pressure is set to :

• Pmax = Plimit + set diff. in VCV, SIMV-VC
• Pmax = Pinsp + set diff. in Bi-Level
• Pmax = PS + set diff. in CPAP/PSV, CPAP/Apnea
Measured airway pressure exceeding the adjusted maximum airway
pressure “P max” triggers the alarm, stops any inspiratory flow, switches
into the expiration phase and opens the active over pressure relief
valve. The alarm is reset when measured airway pressure falls below the
“Pmax” setting.
Rate max (AUTOSET) Upper limit for breathing rate is set to

• measured rate + 150%.
Measured rate exceeding the adjusted maximum rate “Rate max”
triggers the alarm. The alarm is reset when the measured rate falls
below the “Rate max” setting.
Rate min (AUTOSET) Lower limit for breathing rate is set to

• measured rate - 50%
Measured rate falling below the adjusted minimum rate “Rate min”
triggers the alarm. The alarm is reset when the measured rate exceeds
the “Rate min” setting.

6 Operation
The alarm limits for

• Leakage
• Apnea
are not influenced by AUTOSET and always require the operator’s
manual adjustment.
WARNING Ensure stable patient data and proper matching of measured

patient data with the “clinical picture” prior to activating the
AUTOSET function.

6 Operation
6.3.6 ARC (Airway The components of the patient breathing circuit and the patient’s
Resistance Compensation) artificial airway add a large amount of resistance to spontaneous
breathing.
During mechanical ventilation this resistance does not generally affect
the patient. But during spontaneous breathing this resistance becomes
important for the patient during weaning due to increased work of
breathing.
Pressure support (PSV) can be used to partially compensate for this
resistance.
The Centiva/5 also offers a special flow compensation for this airway
resistance with respect to the flow/pressure relationship of the
endotracheal and tracheal tubes. This Airway Resistance
Compensation (ARC) is adjustable according to the type of tube, tube
size and level of compensation. ARC operates in pressure controlled
modes (Bi-Level) and spontaneous modes (CPAP/PSV) for both the
mandatory and the spontaneous breaths. The ARC compensates for the
inspiratory and the expiratory resistance.
To access the ARC menu open the main menu by pushing the
menu button.
Select the function “A R C” by rotating the ComWheel.
Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit

6 Operation
Endot.tube OFF
The ARC menu opens and allows adjustment of Trach.tube OFF
the specific parameters.
Diameter 7.5
Compensat. 50%
Previous menu
Endot.tube Endotracheal tube (E). ON identifies that this type Exit

of tube is being used.
Trach.tube Tracheal tube (T). ON identifies that this type of tube is being used.
Diameter This is the tube’s diameter, marked on the outside of the tube or
packaging. The diameter is adjustable in a range from 4 to 10 mm.
Compensat. This is the level of compensation for the flow dependent resistance in %
of the total compensation. The compensation is adjustable in a range
from 25 to 100%.
Previous menu The function leads back to the previous (main) menu.
Exit The function closes the parameter menu.
Without any activity (button or the ComWheel) all menus close

automatically after 30 secs.
When activating ARC the status line in the

screen shows a message with the selected Tube: E7.5 25%
type of tube (E), the diameter (7.5) and the
level of compensation (25%).
WARNING Always set the tube diameter to the size of the tube being used.
Setting the ARC tube diameter value smaller than the tube being used
will cause overcompensation. This may result in risk to the patient.

6 Operation
Due to the airway pressure being measured within the Centiva/5 the
pressure graph will show an overshoot at the beginning of inspiration,
showing the inspiratory ARC compensation. During expiration the
pressure graph shows an undershoot which shows the expiratory
compensation. The expiratory compensation’s lowest level of pressure
is zero.
Special notice These over- and undershoots are shown on the screen because the
airway pressure is measured within the Centiva/5. Due to the nature of
ARC these over- and undershoots are not applied beyond the patient’s
airway .
The following graph shows the change in the pressure graph (e.g. Bi-
Level mode) when ARC is activated.
Paw
Inspiratory
compensation
Expiratory
compensation
PEEP
0 t
Without ARC With ARC
Special notice Be aware that using high levels of compensation can cause auto
triggering of PSV breaths. To avoid this situation reduce the trigger
window, if necessary.

6 Operation
6.3.7 Nebulized drug During ventilation Centiva/5 allows drug delivery to the patient via the
delivery breathing circuit by means of so called “jet nebulizers”.
Jet nebulizers which have been tested to properly work with Centiva/5 are
listed in the accessory list. However any jet nebulizer which complies with
the following minimum requirements should function correctly:
- Nebulizer flow in between 4 to 12 l/min at a supply pressure of
1,8 bar (25 PSI).
- Pressure stable up to a breathing pressure of 80 cmH2O.
- Leakage under 200 ml/min at a breathing pressure of 60 cmH2O.
Centiva/5 provides capability to measure the data of a jet nebulizer

during system test and to compensate accordingly.
Ventilation modes During adult ventilation drug nebulization will be available in all
ventilation modes: VCV, SIMV-VC, Bi-Level, CPAP/PSV, CPAP/Apnea.
During pediatric ventilation drug nebulization will be available in pressure
controlled ventilation modes: Bi-Level, CPAP/PSV, CPAP/Apnea
The Nebulizer system can be activated in volume controlled modes (VCV
and SIMV-VC), too, but limited volume measurement accuracy of
20 ml ± 15% for tidal volumes below 300 ml may result.
For testing purpose the nebulizer can be turned on in Stand-By mode as
well.
To activate the nebulizer function open the main menu by
Select the function “Nebulizer ON” by rotating the ComWheel.
Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit

6 Operation
An active nebulizer mode can be identified by the Stand-by ON
nebulizer icon in the status line. ASR ON

Parameter menu
Alarm limits
Notice the change in the menu from “Nebulizer ON” Alarm AUTOSET
to “Nebulizer OFF”. Vent. modes

ARC
Nebulizer OFF
System test
Exit
Nebulizer modes At measured breathing rates < 15 /min the nebulizer is controlled in
synchrony with the inspiratory flow.
At measured breathing rates ≥ 15 /min the nebulizer is operated
continuously. In both modes the minute volume is kept constant
compared to the application without nebulizer activity, because
Centiva/5 measures the nebulizer flow during the system test and uses
this for proper compensation of the total flow.
At patients with spontaneous breathing the measured breathing rate

may vary in a wide range and by this may cross the switching criteria at
15 /min. To avoid a too frequent change between inspiratory
synchronous and continuous mode Centiva/5 will watch out for five (5)
breaths to follow before the mode switching will be activated.
The nebulizer mode is switched off during pause time in volume

controlled modes (VCV, SIMV-VC) (I-Flow synchronous !).
The nebulizer operation will turn off automatically after a period of 30

minutes.
The nebulizer can be turned off manually at any time.

6 Operation
Nebulizer and O2 Concentration Depending on the set FiO2 the nebulizer is supplied with either AIR or
O2 to keep the deviation of supplied O2 concentration (O2 – I) in a range
of ± 4 Vol. %.
To avoid increased deviations Centiva/5 turns off the nebulizer mode at

inspiratory flows < 15 l/min and displays a message on the screen
“I-Flow > 15 l/min !”.
If changing ventilation modes with the result of an inspiratory flow < 15

l/min Centiva/5 will display the said message and activate
automatically the parameter “I—Flow” for easy adjusting.
If the I-flow is not changed accordingly and the ComWheel is pushed in
this situation the nebulizer mode is terminated.
With an active nebulizer mode the body color

of the O2-I area turns into yellow (for O2-I 50
21%<FiO2<100%) and shows the calculated 40
O2-I at the Y-piece.
This value is based upon the measured
45 %
inspiratory flow, used nebulizer supply gas and measured nebulizer

flow.

6 Operation
Nebulizer Set up Prepare drug nebulizer according to nebulizer manufacturer’s

instruction.
Drug nebulization during Adult ventilation.

Connect the nebulizer into the
inspiratory line at the y-piece
between y-piece and inspiratory
hose and fix it with the support
arm.
At breathing circuits with fixed

y-piece connections (some
disposable circuits) connect the
nebulizer at the inspiratory
connection of the Centiva/5,
using a standard filter as a
spacer in case of a cart mount.
Drug nebulization during Pediatric ventilation.

Connect the nebulizer between
y-piece and tube or “goose
neck” and fix it with the support
arm.
Ensure the nebulizer is in an upright position. Connect the nebulizer

pressure supply hose to the nebulizer.

6 Operation
Connect the other end of the nebulizer pressure supply hose to the
nebulizer connection on the front
side of the Centiva/5.
Check all connections to be

proper and tight.
CAUTION Nebulized aerosols may affect function of sensors, filters and

HME !
Always use an expiratory filter when nebulizer mode is active to protect
the expiratory flow screen from aerosol sedimentation.
WARNING Do not use filter or HME between patient and nebulizer during
activated nebulization mode. Risk of increasing breathing
resistance.

6 Operation
Nebulizer test Centiva/5 provides capabilities in the System test to measure the
selected nebulizer’s characteristics and compensate accordingly. To do
so connect the nebulizer according to the instructions given above and
perform the system test.
Centiva/5 will
automatically detect if
a nebulizer system is Centiva /5
connected and will System test Rev. x.nn
measure the
System test OK. To start ventilation <Enter>
nebulizer’s flow. Compliance 2.3 ml/mbar

This value is displayed Leakage 15 ml/min
in the system test Nebulizer flow 7,0 l/min
results and will be used Adult
for internal
compensations.
In case the same nebulizer (manufacturer and model) is used, testing

can be simplified by performing the system test once in order for the
Centiva/5 to measure the nebulizer flow of this particular type. At future
usage of this type of nebulizer Centiva/5 will use the data of the last
measured nebulizer in
system test. Centiva /5
When performing a System test Rev. x.nn
system test without a System test OK. To start ventilation <Enter>
connected nebulizer Compliance 2.3 ml/mbar
Centiva/5 will recognize Resistance
Leakage
0.8 mbar/L/s
15 ml/min
this, recall and display Nebulizer flow 7,0 l/min (last value)
the last measured value,
Adult
indicating this by the
message „last value”.
WARNING In case a different nebulizer is used, the system test with

connected nebulizer must be performed for the Centiva/5 to
measure the correct nebulizer characteristics, otherwise
compensation for tidal volume and FiO2 may be incorrect.

6 Operation
6.3.8 System test The system test is started automatically when the Centiva/5 is turned
ON. The system test checks for proper function of the system and
measures the compliance, resistance and leakage of the breathing
circuit.
In case the breathing circuit is changed the Centiva/5 needs the new
breathing circuit’s data so, the system test should be activated at the
earliest possibility.
This can be achieved by turning the ventilator OFF and then ON again.
This menu function allows fast access to the system test.
Special notice This function is only accessible when there is no ventilation mode
active. (System open? screen message)
Select the function “System test” by rotating the

ComWheel.
Stand-by ON
ASR ON
Parameter menu
Alarm limits
Alarm AUTOSET
Vent. modes
ARC
Nebulizer ON
System test
Exit
Push the ComWheel to confirm the selection
The Centiva/5 moves to the system test screen. For details refer to
section 5.8.2 “System test”.

6 Operation
6.3.9 NIV (Non Invasive This function provides the ability to ventilate patients when airways
Ventilation) such as uncuffed tubes for pediatric applications and mask ventilation
are used.
The NIV function maintains sufficient ventilation even with a leak until
the maximum compensation is reached.
The current leakage (leak) Centiva/5
is measured by the system Bi-Level / ASB

15
MV-E
4.2Liter2
12
as the difference between 10
5
Vt-E
350 mL
the inspiratory flow (I-flow)

Ppeak 21
Paw
mbar
14cmH2O
40
Pmin
3cmH2O
and expiratory flow (E-flow).

20
Flow O2-I 25
L/min 21 18
%
-20
Rate 40
This leakage data allows

-40 121/min8
21 12 1:2 0.2 10 3 5
the ventilator to
compensate for the leak.

I
Leak E - flow
I - flow
The leakage compensation is active in all modes.
In VCV and SIMV-VC mode the leak compensation increases the
inspiratory flow up to 50 % of the set tidal volume, according to the
measured leak. The maximum of 50% is set due to safety reasons e.g.
with intubated patients. In case of mask ventilation this compensation
can be increased beyond 50% by increasing the I-flow.
In Bi-Level, CPAP/ASB and CPAP/Apnea mode the leak compensation
increases the inspiratory flow up to the maximum I-Flow setting,
according to the measured leak.
For safety reasons the compensation takes four breaths to activate
when a leak is detected . When the leak disappears the leakage
compensation is reset within one breath to the non-leaking value.
WARNING For safety reasons it is important that the pressure limit (Plimit)
and the leakage alarm limit are set appropriately for the patient’s
condition.

6 Operation
An example for the function of the leakage compensation:
Without leakage compensation active:

In the VCV mode the ventilator delivers a tidal volume of 500 ml. A leak
is in the circuit of about 10%. The ventilator delivers 500 ml pass the
leak and the patient receives 450 ml (500 ml – 10%) .
During exhalation the volume passes the leak a second time. The
patient exhales 450 ml past the leak and the expiratory flow
measurement system receives 405 ml (10% of 450).
With leakage compensation active:

In the VCV mode the Centiva/5 delivers a tidal volume of 500 ml. There
is a leak in the circuit of about 10%. Detecting the 10 % leak allows the
Centiva/5 to increase the delivered tidal volume to 550 ml. The
ventilator delivers 550 ml past the leak and the patient receives 495 ml
(550 ml – 10%).
When exhaling the volume past the leak the patient exhales 495 ml to
the leak and the expiratory flow measurement system receives 445 ml
(495 ml - 10%).
The expiratory flow Centiva/5
measurement does not Bi-Level / ASB

15
MV-E 12
4.2Liter2
compensate for the leak in 10
5
Vt-E
350 mL
Ppeak 21
order to not compromise

Paw
mbar
14cmH2O
40
Pmin
3cmH2O
the volume based alarm

20
Flow O2-I 25
L/min 21 18
%
-20
Rate 40
121/min8
functions.
-40

21 12 1:2 0.2 10 3 5
Leak VT minus leak
Vt plus leak compensation

6 Operation
6.3.10 APD (Automatic Centiva/5 uses the Byflow in the breathing system to automatically
Patient Detection) detect when a patient is connected to the breathing system.
In the following modes this function is used to start or restart the set
ventilation mode with an inspiration:
• Start up waiting phase
• Standby
• ASR suction phase
APD is always active.
When the Centiva/5 is set up for a new patient and a breathing circuit
has been attached and has passed the system test it is recommended
that the Centiva/5 be left in the system test end screen.
This will maintain the seal of the y-piece preventing the activation of the
APD.
Centiva /5
System test OK. To start ventilation <Enter>
Compliance 2.3 ml/mbar

Leakage 15 ml/min
Adult

6 Operation
6.3.11 OCV (Online O2 To online calibrate the O2 sensor in any ventilation mode Centiva/5
sensor calibration) provides an online-O2-sensor calibration function. This function may be
necessary when in long-term ventilation and having an aging O2 sensor.
This function can only be started by a short cut.
The function requires setting the FiO2 to 100%. The entire process will
last at least 5
minutes. Centiva/5
Pushing the 1st and 6th

MV-E 12
15
4.2 2
Liter
soft key
10 Vt-E
5
350 mL
Ppeak 21
simultaneously will 14
Paw
mbar cmH2O
40 Pmin
3
start the Online-O2-
cmH2O
20
Flow O2-I 25
L/min 21 18
%
sensor calibration in
-20
Rate 40
-40 12 8
1/min

any mode. Pushing 21
%
12 1:2 0.2 10
1/min
3 5
sec cmH2O cmH2O cmH2O
the same soft keys

again stops the
Online-O2-sensor
calibration. I
With an active Online-O2-sensor calibration

mode the color of the measured O2-I area O2-I 110
turns into green. When calibration is finished 90
the color changes to white again. 100 %
WARNING Prior to performing the Online-O2-sensor calibration verify that

there are no clinical counter indications for the increased FiO2 to
be delivered to the connected patient. Ensure returning to the
previously selected FiO2 after calibration.

6 Operation
6.3.12 Short cuts The Centiva/5 has several short cuts that allow activation of functions
by soft keys without entering a menu.
ASR ON Pushing the 1st and Centiva/5

3rd soft key Bi-Level / ASB Tube : E 7.5 50% Adult
MV-E 12
simultaneously will
15
4.2Liter2
10 Vt-E
350 mL
start the ASR Paw
5
mbar
Ppeak
14cmH2O
21
function in any 40
20
Pmin
O2-I
3cmH2O
25
mode. Pushing the

Flow
L/min 21 18
%
-20
Rate 40
121/min8
same soft keys
-40

21 12 1:2 0.2 10 3 5
again stops the
ASR mode.
Freeze Pushing the 6th Centiva/5

and 7th soft key Bi-Level / ASB Tube : E 7.5 50% Adult
12
simultaneously will
15 MV-E
4.2Liter2
10 Vt-E
350 mL
freeze the Paw
5
mbar
Ppeak
14cmH2O
21
waveforms. A 40
20
Pmin
3cmH2O
25
message in the
Flow O2-I
L/min 21 18
%
-20
Rate 40
121/min8
screen “Freeze” will
-40

21 12 1:2 0.2 10 3 5
indicate that the
waveforms are not

actualized any
more. The freeze I
function is O
maintained until
canceled by
pushing any button.
CAUTION Unfreeze the screen when done reviewing waveforms.

6 Operation
Nebulizer ON Pushing the 1st and Centiva/5
5th soft key Bi-Level / ASB

15
MV-E
4.2Liter2
12
simultaneously will 10
5
Vt-E
350 mL
start the nebulizer

Ppeak 21
Paw
mbar
14cmH2O
Pmin
function in any
40
3cmH2O
20
Flow O2-I 25
L/min 21 18
mode. Pushing the

%
-20
Rate 40
-40 121/min8
same soft keys Fi02

21
%
Rate
12
1/min
I:E
1:2
Ramp P-Insp PEEP P-ASB
0.2
sec
10
cmH2O
3
cmH2O
5
cmH2O
again stops the

nebulizer function.
OCV ON Pushing the 1st and Centiva/5
6th soft key Bi-Level / ASB

15
MV-E 12
4.2Liter2
simultaneously will 10 Vt-E
350 mL
start the Online-O2-

5
Ppeak 21
Paw
mbar
14cmH2O
sensor calibration
40 Pmin
3cmH2O
20
Flow O2-I 25
21 18
in any mode.
L/min
%
-20
Rate 40
-40 121/min8
Pushing the same Fi02

21
%
Rate
12
1/min
I:E
1:2
Ramp P-Insp PEEP P-ASB
0.2
sec
10
cmH2O
3
cmH2O
5
cmH2O
soft keys again

stops the Online-
O2-sensor
calibration. I

7 Cleaning and Sterilization
In this section 7.1 General advice 7-2

7.2 Disassembly 7-3
7.2.1 Used with HME 7-3
7.2.2 Used with active humidifier 7-4
7.3.1 Removing expiration valve assembly 7-5
7.3.2 Disassemble expiration valve assembly 7-7
7.4 Clean and sterilize 7-8
7.4.1 Housing and control panel 7-8
7.4.2 Expiration valve 7-8
7.5 Reassembly 7-9
7.5.1 Reassemble expiration valve assembly 7-9

7.1 General advice
WARNING Obey applicable safety precautions:

• Read the material data sheet for each cleaning agent.
• Read the operation and maintenance manual for all sterilization
equipment.
• Wear gloves and safety glasses.
• Do not breath the fumes.
CAUTION To prevent damage:

• Refer to the manufacturer’s data if you have questions about a
cleaning agent.
• Do not use organic, halogenated or petroleum based solvents,
anesthetic agents, glass cleaners, acetone or harsh cleaning
agents.
• Do not use abrasive cleaning agents, such as steel wool, silver
polish or silver cleaner.
• Keep all liquids away from electronic parts.
• Do not permit liquids to go into the equipment housing.
• Only autoclave parts that are appointed accordingly.
CAUTION To prevent patient contamination:

• Clean and sterilize Centiva/5 and attached equipment after each
patient.
• Follow general hygiene requirements of your hospital.
• Do not re-use single use components.

7.2 Disassembly
7.2.1 Used with HME Disconnect patient from the ventilator and wait for the “System open?”
message and turn OFF the Centiva/5.
• Remove and dispose of the used HME.

• Remove and dispose of the single use breathing circuit.
• If a reusable breathing circuit was used, remove and clean the
breathing circuit according to manufacturer’s advice.
• If breathing filters were used remove and dispose of the single use
filters or remove and clean the reusable filters according to
manufacturer’s advice.
Centiva/5
MV-E 12
15
4.2Liter2
10
Vt-E
5
350 mL
Ppeak 21
Paw
mbar
14cmH2O
40
Pmin
3cmH2O
20
Flow O2-I 25
L/min 21 18
%
-20
Rate 40
-40 121/min8
21 12 1:2 0.2 10 3 5
HME Exp. line Insp. line

7.2.2 Used with active Disconnect the patient from the ventilator and wait for the “System
humidifier open ?” message and turn OFF the Centiva/5.
Turn OFF the active humidifier and remove the electrical connection.
• Remove and empty the water trap.

• Dispose of the single use water traps, clean and sterilize the
reusable water traps according to manufacturer’s advice.
• Remove and dispose of the single use breathing circuit.
• If a reusable breathing circuit was used, remove and clean the
breathing circuit according to manufacturer’s advice.
• If breathing filters were used, remove and dispose of the single use
filters or remove and clean the reusable filters according to
• Disassemble, clean and sterilize the active humidifier according to
Centiva/5
15 MV-E 12
4.2Liter2
10 Vt-E
5
350 mL
Ppeak 21
Paw
mbar
14cmH2O
40 Pmin
3cmH2O
20
Flow O2-I 25
L/min 21 18
%
-20
Rate 40
-40 121/min8
21 12 1:2 0.2 10 3 5
Water trap

7.3 Expiration valve
7.3.1 Removing expiration The Centiva/5 uses a removable expiration valve assembly for easy
valve assembly cleaning.
To remove the expiration valve assembly connect the Centiva/5 to the

main supply and turn ON the device. Wait for the power-up test to
finish.
After having passed the power-up test, activate the system

test menu by pressing the menu button.

appears and allows the Centiva/5
selection of certain System Test Rev. x.nn
service functions .
Complete system set up, seal Y-piece
Selecting ”Exit” closes
the system test menu
Start system test by pressing <Enter>
Bypass system test
without any activity. Unlock expiration valve
Calibrate O2 sensor
Exit
Adult Pediatric
Select “Unlock expiration valve” by using Bypass system test

the ComWheel and confirming the Calibrate O2 sensor
selection. Exit
No main supply In case there is no main supply available, the internal back-up battery
will release the expiration valve assembly by turning the Centiva/5 on.
The system does not

perform a power-up Centiva/5
test, but prompts the System Test Rev. x.nn
user with the following No line supply
screen to select the Check power cord and fuses
”Unlock expiration Bypass system test
valve” function. Unlock expiration valve

Calibrate O2 sensor
Exit
Adult Pediatric
Select “Unlock expiration valve” by using Bypass system test

the ComWheel and confirming the Unlock expiration valve
Calibrate O2 sensor
selection. Exit

The Centiva/5 prompts with the following screen:
The system unlocks the

expiration valve Centiva/5
assembly and the
assembly can now be
removed from the
Expiration valve unlocked
Ready to be removed from device
device.
The operator can remove

the valve assembly from the
system by moving it out as
shown in the figure.
Turn OFF the Centiva/5 and disconnect it from the line supply, if
applicable.

7.3.2 Disassemble The expiration valve is easy to take apart. Remove the stainless steel
expiration valve assembly plate and then remove the PEEP membrane assembly.
Inspect the stainless steel plate A

(A) and the PEEP membrane
assembly (B) for distortion, B
deterioration and/or cracks and
replace, if necessary.
Inspect the block, expiratory

22mm connector (D) and sealer
port (C) for distortion,
C D

7.4 Clean and sterilize
7.4.1 Housing and control Turn OFF the Centiva/5 and ensure that the mains power cord and the
panel 24 V DC external supply power cord are disconnected.
Use a soft towel to clean the housing and control panel. When using
fluid cleaners use a mild detergent and do not permit liquids to go into
the equipment housing.
Ensure that the housing and control panel are dried completely before
reconnecting the Centiva/5 to an electrical supply or prior to turning the
device on.
7.4.2 Expiration valve The expiration valve assembly and its components can be cleaned and
disinfected with cleaning solvents, such as CIDEX. CIDEX plus is not
recommended.
• Submerge all components of the expiration valve assembly in

activated solvent solution for the time required by the solvent’s
manufacturer.
• Rinse all components as indicated by the solvent’s manufacturer.
• Rinse the inner part of the block
through the opening of the PEEP
membrane assembly.
• To ensure proper cleaning of

the flow screen rinse the
flow screen through the
retainer’s opening holes.
CAUTION Completely dry all components prior to re-assembly. Do not use

high pressure gas to dry.
CAUTION Do not use brushes to clean the components.
The expiration valve assembly and its components can be sterilized by

using standard autoclaving procedures with either 121°C/20 minutes
or 134°C/5 minutes.

7.5 Reassembly
7.5.1 Reassemble Insert the PEEP membrane assembly (B) into the block with the note
expiration valve assembly “TOP” facing you.
Verify the stainless plate (A) is

positioned on top of the A
membrane assembly.
B
Check for proper seating of all
components prior to reinsertion
into the system’s locking device.
The PEEP membrane assembly 3

comes completely assembled.
In the event the PEEP membrane 2
assembly comes apart or parts of
the assembly need replacement 1
push the nipple of the PEEP TOP
seal membrane (1) through the
PEEP PSU plate (2) (beveled edge
up) and finally through the PEEP
silicone membrane (3).
When inserting the PEEP membrane assembly into the expiration valve
block make sure the PEEP silicone membrane faces the valve seat and
verify the proper assembly by looking for the “TOP” mark on top of the
PEEP membrane assembly after insertion.
CAUTION Handle carefully the silicone PEEP membrane assembly.

7.5.2 Reinsertion of Slide the entire assembly into the expiration valve locking mechanism
expiration valve assembly slot with the expiration port to the front.
The expiration valve

assembly should be
inserted smoothly .
Special notice Do not try to overcome a high resistance or try to force the assembly
back into the slot. If problems occur with reinsertion check for proper
assembly of the expiration valve.
The Centiva/5 will automatically recognize the insertion and lock the
expiratory valve assembly in, if powered by a main supply. After proper
locking the system performs a power-up test to verify proper operation.
Upon successful test

the following screen is Centiva/5
prompted and asks the System test Rev. x.nn
user to start the system
Complete system set up, seal y-piece
test.
Start system test <Enter>
Adult Pediatric
In case reinsertion was performed with the Centiva/5 powered by the

internal back-up battery, the valve assembly will not lock. Locking will
be performed the next time the Centiva/5 is turned on with main power
supply and after passing the power-up test.

8 Alarms and messages
In this section 8.1 Alarm modality 8-2

8.2 Alarm messages 8-4
8.3 Other messages 8-8
8.3.1 Messages during power up 8-8
8.3.2 Messages during system test 8-11
8.3.3 Messages during O2 calibration 8-19
8.3.4 Messages during operation 8-20

8.1 Alarm modality
The Centiva/5 software includes self tests that determine if the

operating software is functioning properly and if the electronic and
pneumatic circuits are functional. The self tests include:
• Power-up test
• System test
• In-operation test
Messages and alarms generated in this testing will be explained in the

following.
During system test the complete combination of Centiva/5 and it’s

used breathing system components and accessories are tested for
proper function AND performance. In case a problem is identified
during system test,
• verify the accessories and breathing circuit components
used are listed in the Centiva/5 “Accessory list”.
• verify the accessories and breathing circuit components
used are assembled according to the instructions given
in this manual.
• follow the particular message trouble shooting guidance
in the following.
Important note Be aware that system test messages may appear because of artifacts
during the system test sequence. These artifacts could be moving ,
manipulating and handling of accessories and breathing circuit
components while performing the tests.
In this case no malfunction of Centiva/5 has created the message
performing the system test again will allow to pass the system test
successfully.

Centiva /5 distinguishes between high and low priority alarms. The

following describes the Centiva/5’ s high and low priority alarms.
High priority
Activity Screen Red alarm light Audible alarm
Alarm is active - Display alarm message in red color ON, flashing ON
Confirming the - Display alarm message in red color. ON, continuous OFF
alarm by activating - Start “2min” silence.
the alarm silence - Start timer in screen
button
Alarm is still active - Display alarm message in red color. ON, flashing ON
after the “2min”
silence time
Alarm is reset - Display alarm message in yellow OFF OFF
color
Confirming the - Displayed alarm message in yellow OFF OFF
alarm reset by color removed from screen.
activating the alarm
silence button
Low priority
Activity Screen Yellow alarm light Audible alarm
Alarm is active - Display alarm message in red color ON, continuous OFF
Confirming the - Display alarm message in red color. ON, continuous OFF
alarm by activating - Start timer in screen
the alarm silence
button
Alarm is reset - Display alarm message in yellow OFF OFF
color
Confirming the - Displayed alarm message in yellow OFF OFF
alarm reset by color removed from screen.
activating the alarm
silence button

8.2 Alarm messages
No. Alarm Priority Set condition Action of Centiva/5

1 “Pressure high” High In all modes: High priority alarm.
If Ppeak ≥ Pmax End inspiration (set
inspiratory flow to zero)
and start expiration (set
expiratory valve to PEEP)
Sequence #2 to follow: Additional to the above:

If Ppeak > (Pmax + 2 cmH2O) Open inspiratory safety
valve
2 “Pressure low” High VCV mode: High priority alarm
If Ppeak < (PPEEP + 5 cmH2O) after 15
sec from start of insp.
SIMV -VC mode:
If Ppeak < (PPEEP + 2 cmH2O) after 15
sec from start of insp.
Bi-Level mode:
If Ppeak < ((Pinsp + PPEEP) /2 ) – 0.5
cmH2O after 15 sec from start of insp.
In all modes: High priority alarm
If Pairway < 0 cmH2O for more than 0.5 Open sub atmospheric
sec pressure relief valve
3 “Pressure High In all modes: High priority alarm
sustained” If Pmin > (PPEEP + 2 cmH2O) within one End inspiration (set
breath inspiratory flow to zero)
and start expiration (set
expiratory valve to PEEP)
In all modes: Additional to the above:
If Pairway > (Pset + 5 cmH2O) within 0.5 Open inspiratory safety
sec valve
4 “Apnea” High VCV, SIMV-VC, Bi-Level, CPAP/PSV High priority alarm
mode:
System open (see messages) for
longer than Apnea time
CPAP/Apnea mode: High priority alarm
Since the last expiration no breath is Bi-Level mode is started
detected in set apnea time Apnea time displayed on
Or screen
measured rate < 4 bpm After 5 min flashing
visual and audible
alarms are turned OFF
and message remains
on screen


5 “Leakage” High In all modes: High priority alarm
If ((Vinsp-Vexp) / Vinsp) * 100 > set
leakage (5% - 95%)
over a rolling average of 4 breaths
6 “Vt not High VCV, SIMV-VC modes: High priority alarm
delivered” If Ppeak ≥ Plimit
And
Vt measured ≤ Vt set * 0.8
after 15 sec from start of inspiration
7 “MV low” High In all modes: High priority alarm
If calculated MV over 61 seconds or
over 10 breaths (whichever is
smaller) < set MV limit (0.5 – 50
L/min)
8 “MV high” High In all modes: High priority alarm
If calculated MV over 61 seconds or
over 10 breaths (whichever is greater)
> set MV limit (0.5 – 50 L/min)
9 “Sensor High In all modes: High priority alarm

mismatch” If any of the three flow sensor delivers
implausible data
Or if the insp. pressure sensor
delivers implausible data
Or if the insp. pressure sensor reads
≤ –9 cmH2O for more than 500 ms
Or if the insp. pressure sensor reads
> 80 cmH2O for more than 500 ms
Or if an additional external flow is
detected
10 “Battery failure” High In all modes: High priority alarm
If sensed battery voltage > 29 V for
more than 1 sec
11 “Battery low” High In all modes: High priority alarm
If sensed battery voltage < 22.5 V for
more than 1 sec


12 “Line supply Low In all modes: Low priority alarm
fail” If line supply voltage < 95 VAC (200
VAC) for more than 100 msec
And
If external battery voltage < 22.5 V for
more than 100 msec
Or if line supply voltage > 135 VAC
(255 VAC)
13 “Fan failure” High In all modes: High priority alarm
If sensed fan rotation is too low
Or If sensed fan rotation is too high
14 “Heater failure” Low In all modes: Low priority alarm
If the heater temp is < 5° C
Or if the heater temp is > 60 °C
Or if the heater current is too high
Or if heater power is too high
Or if the heater temp. is < 42°C or if
heater temp. is > 48°C for more than
60 sec
15 “O2 supply fail” High In all modes: High priority alarm
If FiO2 set > 0.21
And
the O2 pressure < 29 PSI
16 “AIR supply fail” High In all modes: High priority alarm
If FiO2 set < 1.0
And
the AIR pressure < 29 PSI
17 “Rate low” High In all modes: High priority alarm
If measured rate < set rate low limit
18 “Rate high” High In all modes: High priority alarm
If measured rate > set rate high limit
19 “Power PCB fail” High In all modes: High priority alarm
If main bus voltages are failing
20 “Display failure” High In all modes: High priority alarm
If connection between control panel
and main engine is defective
Or if display back light is defective


21 “O2 sensor fail” High In all modes: High priority alarm
If O2 measured value ≤ 10 %
Or if O2 measured value ≥ 120 %
22 “O2 concentr. High In all modes: High priority alarm
low” If O2 measured value < set O2 low
limit
23 “O2 concentr. High In all modes: High priority alarm
high” If O2 measured value > set O2 high
limit
24 “P limit Low VCV, SIMV-VC modes: Low priority alarm
reached” If Ppeak ≥ Plimit
25 “Button failure” Low In all modes: If a button is active for Low priority alarm
more than 5 sec

8.3 Other messages
8.3.1 Messages during power-up test

Message Set condition Action Reset condition
“No line supply” Line power supply fails System is supplied with If line power supply is
Or external DC power power from internal restored Or
supply fails battery If external DC power
supply is reconnected
“Battery depleted” Internal back up battery System is not able to be If internal back up
empty operated battery is recharged
“DC mains supply” External DC supply is System is supplied by If external DC supply is
active external DC supply disconnected
“Test active, wait for xx System is in test System performs If test is successfully
secs” procedure for at least xx automatic test finished
seconds procedure Or
If test has identified any
system errors
“Controller B no Controller problems System may not be Call authorized service
function” identified operated specialist
“Watchdog controller A Watchdog problems System may not be Call authorized service
(or B) does not open (or identified operated specialist
close).”
“No line supply, check Line power supply fails System is supplied with If line power supply is
line power cord and power from internal restored
fuse” battery. System may not
be operated
“External power supply External power supply System is supplied with If external power supply
failure, voltage too high, voltage is too high power from internal voltage is in the proper
check external power battery voltage range
supply” System may not be
operated
“Internal power supply Internal power supply System may not be Call authorized service
failure. System may not fails operated specialist
be operated. Call service
specialist”
”Battery depleted The internal back up Recharge battery while Battery has reached
(voltage < 22.0 V) battery is depleted system is supplied with sufficient voltage level
System not ready for line power or external within 10 minutes of
operation. If this DC power prior to recharging.
message appears for operation If not:
more than 10 min, Call authorized service
battery needs specialist
replacement”


“Battery is empty The internal back up Recharge battery while Battery has reached
(voltage < 23.5 V). If battery is empty. The system is supplied with 24.0 V within 20
24.0 V is not reached in battery voltage is x V. line power or external minutes.
20 min, battery needs DC power prior to If not:
replacement.” operation. Call authorized service
specialist
“Battery or recharger The internal back up System may not be Call authorized service
defective. Call service battery is depleted operated specialist
specialist” Or
The recharger for the
internal back up battery
is defective.
“Battery cannot be The internal back up System may not be Call authorized service
switched on ! battery is not operable. operated specialist
Call service specialist”
“Fan failure. The internal fan is not System may not be Call authorized service
Call service specialist” operable. operated specialist
“Temperature sensor The inspiratory System may not be Call authorized service
insp. Flow malfunction. temperature sensor is operated specialist
Call service specialist” not operable.
“Watchdog does not turn The heater is not System may not be Call authorized service
off heater. Call service operable. operated specialist
specialist.”
“Exp. flow sensor heater The heater is not System may not be Call authorized service
cannot be switched on. operable. operated specialist
Call service specialist.”
“Heater or heater current The heater is not System may not be Call authorized service
limiter failure. Call operable. operated specialist
service specialist.”
“Heater or heater current The heater is not System may not be Call authorized service
limiter failure. Call operable. operated specialist
“Heater temperature The heater is not System may not be Call authorized service
sensor malfunction. Call operable. operated specialist
“Expiration valve missing The expiration valve System may not be Re-insert expiration
or not in proper assembly is not inserted operated valve assembly
position.” and locked.
“Expiration valve The expiration valve Remove the expiration Re-insert expiration
unlocked. Ready to be assembly is unlocked valve assembly. valve assembly
removed from device.” and can be removed


“Malfunction of locking The locking mechanism Unlock the expiration Re-insert expiration
mechanism of expiration has not properly locked valve assembly by valve assembly
valve. Unlock exp. valve the expiration valve selecting the according
again via system test assembly. system test menu
menu.” function
“EPROM versions do not Panel EPROM version System may not be Exchange entire panel
match. Check software and internal main board operated with a matching version
rev. no of panel and EPROM versions do not Or
main engine” match. Call authorized service
specialist
“Controller or RAM on Controller or RAM System may not be Call authorized service
main PCB defective. Call problems are identified operated specialist
service specialist” on main PC board
“Controller or RAM on Controller or RAM System may not be Call authorized service
front PCB defective. Call problems are identified operated specialist
service specialist” on panel PC board
“EPROM on main PCB EPROM problems are System may not be Call authorized service
defective. Call service identified on main PC operated specialist
specialist” board
“EPROM on front PCB EPROM problems are System may not be Call authorized service
defective. Call service identified on panel PC operated specialist
specialist” board
“EEPROM on main PCB EEPROM problems are System may not be Call authorized service
specialist” board
“EEPROM on front PCB EEPROM problems are System may not be Call authorized service
defective. Call service identified on panel PC operated specialist
specialist” board
“Button defective or Any front panel button is System may not be Check for permanently
permanently pressed. defective operated activated button on front
Release button or call Or any button is panel
service specialist” permanently activated Or call authorized service
specialist
“Buzzer on main PCB Buzzer problems are System may not be Call authorized service
specialist” board
“Buzzer on front PCB Buzzer problems are System may not be Call authorized service
defective. Call service identified on front PC operated specialist
specialist” board

8.3.2 Messages during system test

“Complete system set up. System has successfully Complete system set up Proceed with system
Seal y-piece. Start passed power up test and with breathing system test by pushing <Enter>
system test by pressing . is ready to start system components attached .
<Enter>” test Seal y-piece by plugging
it onto the sealer on the
expiration valve block
“No O2 gas supply. Insufficient O2 supply Check for proper O2 gas O2 supply pressure
Check O2 gas supply or pressure supply exceeding 29 PSI
for single gas AIR-supply Or
press <Enter>” Proceed with system
test by pushing <Enter>
“No AIR gas supply. Insufficient AIR supply Check for proper AIR gas AIR supply pressure
Check AIR gas supply or pressure supply exceeding 29 PSI
for single gas O2-supply Or proceed with system
press <Enter>” test by pushing <Enter>
“Oxygen flow sensor O2 flow sensor is Restart the system test O2 flow sensor signal
miscalibrated or miscalibrated within proper offset
defective. Measured Or range
offset out of range. O2 flow sensor is Or proceed with system
Call service specialist. defective test by pushing <Enter>
Press <Enter>” Or call authorized
service specialist
“Oxygen flow valves do Insufficient O2 supply Check for proper O2 gas O2 supply pressure
not open or no signal pressure supply exceeding 29 PSI
from oxygen flow sensor. Or proceed with system
Check O2 supply and test by pushing <Enter>
press <Enter>”


“Oxygen flow offset valve O2 flow sensor offset Restart the system test O2 flow offset valve
does not react. Call valve problem identified operates properly
service specialist. Press Or proceed with system
<Enter>” test by pushing <Enter>
Or call authorized
service specialist
“Oxygen valves do not O2 valves do not Disconnect device from O2 valves operate
properly close. Check 02 properly close 02 gas supply properly
gas supply or call service Or O2 gas supply Or Proceed with system
specialist. Press pressure too high test by pushing <Enter>
<Enter>” Or O2 valve seat dirty Or call authorized
service specialist
“2nd oxygen flow valve O2 flow valve problem Restart the system test Proceed with system
does not react. Call identified test by pushing <Enter>
service specialist. Press Or call authorized
<Enter>.” service specialist
“Malfunction in oxygen O2 flow valve problem Restart the system test Proceed with system
valve testing. Test takes identified test by pushing <Enter>
too long, repeat test or Or call authorized
call service specialist. service specialist
Press <Enter>”
“Limited flow in oxygen O2 flow is limited to less Check O2 gas supply for Sufficient flow in O2 gas
gas supply. Check gas than 110 L/min. sufficient flow delivery. supply
supply for sufficient flow Check gas supply line Or proceed with system
delivery” filters. test by pushing <Enter>
Or call authorized
service specialist
“AIR flow sensor AIR flow sensor is Restart the system test AIR flow sensor signal
offset out of range. Call AIR flow sensor is Or proceed with system
service specialist. Press defective test by pushing <Enter>
<Enter>” Or call authorized
service specialist


“AIR flow valves do not Insufficient AIR supply Check for proper AIR gas AIR supply pressure
open or no signal from pressure supply exceeding 29 PSI
AIR flow sensor. Check Or proceed with system
AIR gas supply and press test by pushing <Enter>
<Enter>”
“AIR flow offset valve AIR flow sensor offset Restart the system test AIR flow offset valve
does not react. Call valve problem identified operates properly
<Enter>” test by pushing <Enter>
Or call authorized
service specialist
“AIR valves do not AIR valves do not Disconnect device from AIR valves operate
properly close. Check properly close AIR gas supply properly
AIR gas supply or call Or AIR gas supply Or proceed with system
service specialist. Press pressure too high test by pushing <Enter>
<Enter>” Or AIR valve seat dirty Or call authorized
service specialist
“2nd AIR flow valve does AIR flow valve problem Restart the system test Proceed with system
not react. Call service identified test by pushing <Enter>
specialist. Press Or call authorized
<Enter>.” service specialist
“Malfunction in AIR valve AIR flow valve problem Restart the system test Proceed with system
testing. Test takes too identified test by pushing <Enter>
long, repeat test or call Or call authorized
service specialist. Press service specialist
<Enter>”
“Limited flow in AIR gas AIR flow is limited to less Check AIR gas supply for Sufficient flow in AIR gas
supply. Check gas than 110 L/min. sufficient flow delivery. supply
supply for sufficient flow Check gas supply line Or proceed with system
delivery” filters. test by pushing <Enter>
Or call authorized
service specialist
“Pressure sensor Pressure sensor is Restart the system test Pressure sensor signal
offset out of range. Call Pressure sensor is Or proceed with system
service specialist. Press defective test by pushing <Enter>
<Enter>” Or call authorized
service specialist


“No pressure increase in No pressure increase Check the breathing Pressure increase is
breathing circuit. Check measured up to 50 circuit for leaks and measured in the
breathing circuit and cmH2O within 5 secs check the expiration breathing circuit
expiration valve for leaks caused by a non-sealed valve for proper function. Or Proceed with system
<Enter>.” y-piece test by pushing <Enter>
Or A leak in the breathing Or call authorized
circuit service specialist
Or A leak in the
expiration valve
“Pressure sensor offset Pressure sensor offset Restart the system test Pressure sensor offset
valve does not react. Call valve problem identified valve operates properly
<Enter>.” test by pushing <Enter>
Or call authorized
service specialist
“Pressure sensor Low pressure increase Check the breathing Pressure increase is
malfunction. Leakage, measured caused by a circuit for leaks and measured in the
check expiration valve. pressure sensor check the expiration breathing circuit
Call service specialist. malfunction valve for proper function Or proceed with system
Press <Enter>.” Or a leak in the breathing And restart the system test by pushing <Enter>
circuit test. Or call authorized
Or a leak in the service specialist
expiration valve
“Electronic pressure Electronic over pressure Restart the system test Electronic pressure
safety valve in inspiratory relief valve in inspiration and verify the y-piece is safety valve opens
line does not open. Call line does not react properly sealed . properly
service specialist. Press Or pressure release too Or proceed with system
<Enter>.” slow test by pushing <Enter>
Or call authorized
service specialist
8-14 CURM Centiva/5, CM-920041, rev. 2.22


“No pressure increase in No pressure increase Check the breathing Pressure increase is
system. Leakage: xx measured caused by a circuit for leaks and seal measured in the
ml/min. Seal Y-piece or non-sealed y-piece y-piece breathing circuit
check breathing circuit Or a leak of xx ml/min in Or proceed with system
for leaks. Press the breathing circuit test by pushing <Enter>
<Enter>.”
“Leakage in breathing Leakage in breathing Check the breathing Seal leaks
circuit too high. Leakage: circuit exceeds 1,000 circuit for leaks Or proceed with system
xx ml/min. Check mL/min. test by pushing <Enter>
breathing circuit and
expiratory valve for leaks.
Press <Enter>.”
“Operational valve Pressure increase Do not squeeze Proper pressure
malfunction. Call service measured with sealed breathing circuit increase is measured in
specialist. Press valves components while in the breathing circuit
<Enter>.” system test Or proceed with system
“Nebulizer valve does Pressure increase Do not squeeze Proper pressure
not properly close. Call measured with sealed breathing circuit increase is measured in
service specialist. Press nebulizer valves components while in the breathing circuit
<Enter>.” system test Or proceed with system
“Expiratory resistance Expiratory resistance Check breathing circuit Expiratory resistance
too high. Check exceeding 20 cmH2O for kinked hoses or below 20 cmH2O /L/s
breathing circuit and /L/s components causing Or proceed with system
expiratory valve for high resistance and test by pushing <Enter>
resistance. Press check expiratory valve
<Enter>.” assembly
“Expiratory valve data Expiratory valve data Check breathing circuit Expiratory valve data in
not matching. Check does not match with for kinked hoses or proper range
breathing circuit. Press resistance and components causing Or proceed with system
<Enter>.” compliance data high resistance test by pushing <Enter>


“Expiration valve cannot Expiration valve cannotCheck breathing circuit Expiration valve can
control P < 4 cmH2O. control pressure < 4 for leaks and check control pressure < 4
Check proper assembly cmH2O. expiratory valve for cmH2O
of expiration valve or call proper assembly and Or proceed with system
service specialist. Press check breathing circuit test by pushing <Enter>
<Enter>.” for kinked hoses or
components causing
high resistance
“Over pressure relief Over pressure relief valve Restart the system test Over pressure relief
valve P < 65 cmH2O. Call reacts on pressure < 65 valve operates between
service specialist. Press cmH2O 65 and 85 cmH2O
<Enter> Or proceed with system
“Over pressure relief Over pressure relief valve Restart the system test Over pressure relief
valve P > 85 cmH2O. Call reacts on pressure > 85 valve operates between
service specialist. Press cmH2O 65 and 85 cmH2O
<Enter> Or proceed with system
“Expiratory flow sensor Expiratory flow sensor is Remove expiratory valve Expiratory flow sensor
miscalibrated or miscalibrated assembly and check o- signal within proper
defective. Measured Or flow sensor is ring of flow offset range
offset out of range. Call defective measurement port Or proceed with system
service specialist. Press Or flow screen is dirty or Or check flow screen test by pushing <Enter>
<Enter>.” clocked Or call authorized
service specialist
“Expiration flow offset Expiration flow sensor Remove expiratory valve Expiration flow offset
valve does not react or offset valve problem assembly and check o- valve operates properly
wrong signal from identified ring of flow Or proceed with system
expiration flow sensor. Or flow sensor is measurement port test by pushing <Enter>
System may not be defective Or check flow screen Or call authorized
operated. Call service Or flow screen is dirty or service specialist
specialist. Press blocked
<Enter>.”
“Expiration flow offset Exp. flow sensor offset Restart the system test Exp. flow offset valve
valve does not react. Call valve problem identified operates properly
Or call authorized
service specialist


“Exp. flow sensor value Expiration flow sensor Remove expiration valve Expiration flow sensor
too low with AIR flow. value too low with AIR from lock, reassemble signal in proper range
Call service specialist. flow. and reinsert prior to Or proceed with system
Press <Enter>.” restarting the system test by pushing <Enter>
test Or call authorized
service specialist
too high with AIR flow. value too high with AIR from lock, reassemble signal in proper range
Call service specialist. flow and reinsert prior to Or Proceed with system
Press Or flow screen is dirty or restarting the system test by pushing <Enter>
<Enter>.” blocked test Or Call authorized
Or check flow screen service specialist
too high with O2 flow. value too high with O2 from lock, reassemble signal in proper range
Call service specialist. flow and reinsert prior to Or proceed with system
Press <Enter>.” Or flow screen is dirty or restarting the system test by pushing <Enter>
blocked test Or call authorized
Or check flow screen service specialist
too low with O2 flow. value too low with O2 from lock, reassemble signal in proper range
Call service specialist. flow. and reinsert prior to Or proceed with system
Press <Enter>.” restarting the system test by pushing <Enter>
test Or call authorized
service specialist
“Nebulizer flow with AIR Expiration flow sensor Check nebulizer for Expiration flow sensor
out of range. value too low with AIR proper operation and signal in proper range
Call service specialist. Nebulizer flow. tightness Or proceed with system
Press <Enter>.” test by pushing <Enter>
Or call authorized
service specialist
“Nebulizer flow with O2 Expiration flow sensor Check nebulizer for Expiration flow sensor
out of range. value too low with O2 proper operation and signal in proper range
Call service specialist. Nebulizer flow. tightness Or proceed with system
Press <Enter>.” test by pushing <Enter>
Or call authorized
service specialist
“Nebulizer flow data Nebulizer flow data Check nebulizer type to Nebulizer flow data in
does not match. Call incorrect. be within necessary proper range
service specialist. Press specifications . Or proceed with system
Or call authorized
service specialist


“Oxygen sensor value too Oxygen sensor value Verify proper O2 supply Oxygen sensor values in
low. Re-calibrate sensor. below 19% at 21% and re-calibrate the proper range
Press <Enter>.” setting. oxygen sensor Or proceed with system
“Oxygen sensor value too Oxygen sensor above Verify proper AIR supply Oxygen sensor values in
high. Re-calibrate 24% at 21% setting. and re-calibrate the proper range
sensor. Press <Enter>.” oxygen sensor Or proceed with system
“Open y -piece.” The test sequence Open y-piece or remove Opened y-piece.
requires opening the y- y-piece from sealer of
piece to measure the expiration block
inspiratory resistance
“Measured inspiratory Inspiratory resistance Check breathing circuit Inspiratory resistance in
resistance too high. exceeding 6 cmH2O for kinked hoses or proper range
Check breathing circuit. /L/s. components causing Or proceed with system
Press <Enter>.” high resistance test by pushing <Enter>
“Measured resistance Breathing circuit Check breathing circuit Breathing circuit
out of range. Check resistance above 40 for kinked hoses or resistance below 40
breathing circuit. Press cmH2O /L/s components causing cmH2O /L/s
<Enter>.” Or resistance could not high resistance Or resistance could be
be detected properly And check expiration detected properly
valve for proper Or proceed with system
assembly test by pushing <Enter>
And do not manipulate
breathing system while
in test
“System test OK. To start System test is finished. Connect y-piece to n/a
ventilation <Enter> Total Compliance, insp. patient and start
Compliance xx ml/ resistance and total ventilation by pushing
cmH2O leakage data of used <Enter>
Resistance xx cmH2O breathing circuit are
/L/s identified and will be
Leakage x mL/min“ used for compensation
Nebulizer flow x l/min during following
(last value) ventilation. Flow of
Exp. flow sensor data re- adapted nebulizer is
adjusted“ measured or last
measured value is used.
Expiration flow sensor
was readjusted

8.3.3 Messages during O2 calibration

“No signal: wrong gas or If sensor signal does not Ensure proper O2 gas Senor signal exceeds
sensor defective” exceed 40% at supply 40%at calibration with
calibration with 99% O2 Or call authorized 99% O2
service specialist to
replace sensor
“Signal low: sensor If sensor signal does not Ensure proper O2 gas If sensor signal is in
used-up or sensor reach minimum data supply between minimum and
failure” sheet value at 99% Or ensure proper AIR gas maximum data sheet
Or supply values at 21% with AIR
21% O2 Or repeat calibration And
procedure 99% with O2
Or call authorized
service specialist to
replace sensor
“Signal high: sensor If sensor signal exceeds Ensure proper O2 gas If sensor signal is in
failure or PCB failure” maximum data sheet supply between minimum and
value at 99% Or ensure proper AIR maximum data sheet
Or supply values at 21% with AIR
21% O2 Or repeat calibration And
procedure 99% with O2
Or call authorized
service specialist
“Calibration successfully If calibration settles Finish the calibration n/a
finished” properly at procedure
21% with AIR
and
99% with O2

8.3.4 Messages during operation

Message Set condition Meaning Reset condition
“Battery xx Min” In all modes: System power supply In all modes:
If line power supply fails from internal back-up If line power is
Or battery. Remaining reconnected
If external DC power operating time on battery Or
supply fails is “xx Min” If external DC power
Or supply is reconnected
If internal battery is been Or
recharged If internal battery is fully
charged
“Tube a, xx, yy %” In all modes: ARC is active for In all modes:
If Airway resistance a type of tube with If ARC is turned off
compensation ARC is xx mm diameter and
used yy % compensation
“No test” In all modes: System test to identify Perform system test
If system test had not breathing circuits
been performed compliance, resistance
and leakage was not
performed. System uses
default data to
compensate.
Compliance
compensation therefore
may not be appropriate
“Adult” In all modes: For all system settings Select “pediatric” to
System is in “adult adult mode default change
mode” values are used
“Pedia” In all modes: For all system settings Select “Adult” to change
System is in “pediatric pediatric mode default
mode” values are used
“Standby” System was moved into System starts By-flow Connect a patient to the
standby mode after 15 secs to identify y-piece
reconnection of a patient Or
(APD). Activate the On/Off
All alarms are silenced button for more than 3
secs to turn off the
system


“Apnea x.xx” No breathing action is Patient has stopped Perform breathing
detected within the last breathing for more than activities and start
apnea time delay. the apnea delay time. He ventilation support
is apnetic for x.xx Min&
secs
“Apnea vent.” No breathing action is Patient has stopped Check reason for
detected within the last breathing for more than patient’s apnea and
apnea time delay. the apnea delay time. verify ventilation mode
System has started apnea
back up ventilation mode
“Pre oxygen x.xx” Automatic suction Pre oyxgenation phase of Deactivate automatic
routine ASR activated. automatic suction routine suction routine ASR
1st phase is in operation for at least Or disconnect patient
x.xx Min & sec.
“Suction x.xx” Automatic suction System releases pressure Deactivate automatic
routine ASR activated. to zero, silences all alarms suction routine ASR
2nd. phase and stops and waits for Or reconnect patient
the patient to be
disconnected for bronchial
suction. Phase is in
process for at least x.xx
Min & sec
“Post oxygen x.xx” Automatic suction Post-oxygenation phase of Deactivate automatic
routine ASR activated. automatic suction routine suction routine ASR
3rd phase is in operation for at least
x.xx Min & sec
“Freeze” Graphic freeze function Graphics in screen are Deactivate freeze
was activated frozen for better analysis. function by pushing any
button
“System open?” Pressure below PEEP System cannot detect Reconnect patient
Or sufficient pressure Or activate the On/Off
patient disconnected increase. button for more than 3
secs to turn off the
system


The nebulizer function Nebulizer function is Turn OFF nebulizer
was activated. active. function.
The external DC supply System is supplied by Turn OFF or disconnect
was activated. external DC power external power supply
supply. OR
Turn on AC mains line
supply.
“I=xx s, P=yy %, E=zz s” A soft key with a direct Information about the Push ComWheel to
influence to the ventilator absolute timing: confirm displayed data
timing was activated
I= xx s
inspiration time = xx
seconds
P= yy %
inspiratory pause = yy %
of inspiration time
E= zz s
expiration time = zz
seconds
“Switch off device? Yes: System in Standby Software switch off of Push any button to
Enter, No: any button” Or system open ? Centiva /5 by activating return to normal
And On/Off button the <Enter> button operation
activated for more than 3
secs
“System error # ” Any system error System error # has Shut down system,
detected during occurred. restart and perform
permanent system check power up test
Or call authorized service
specialist

9 Maintenance
In this section 9.1 General 9-2

9.2 Oxygen sensor calibration 9-3
9.2.1 Start calibration 9-3
9.2.2 Stop calibration 9-4
9.3.1 Remove valve assembly 9-5
9.3.2 Replace components 9-7
9.3.3 Reassembly 9-8
9.4 Additional maintenance 9-10
9.4.1 Every twelve (12) months 9-10
9.4.2 Every twenty four (24) months 9-10

9 Maintenance
9.1 General
The Centiva/5 ICU ventilator is designed for minimum maintenance.

There are only two components that require operator’s maintenance
during use:
• Oxygen sensor calibration

• Expiration valve
Beside this operator’s maintenance additional maintenance is required

by authorized service personal every twelve months. This includes a
safety check of the system.

9 Maintenance
9.2 Oxygen sensor calibration
The Centiva/5 uses a galvanic fuel cell type oxygen sensor to measure
the inspiratory oxygen concentration. Fuel cells have an aging effect
that requires periodic re-calibration as it is exposed to oxygen.
The oxygen sensor calibration is an automatic procedure that needs
only to be started by the operator.
Re-calibrate the Oxygen sensor on a two weeks basis or whenever the
set FiO2 differs by more than 5 Vol% with the measured FiO2 value.
9.2.1 Start calibration Turn ON the Centiva/5 and wait for the power-up test to finish.
After having passed the system power-up tests and before

starting normal operation the system test menu can be
activated by pressing the menu button.

selection of certain System Test Rev. x.nn
service functions . Complete system set up, seal Y-piece
Selecting “Exit” closes Start system test by pressing <Enter>
the system test menu Bypass system test
without any activity.

Calibrate O2 sensor
Exit
Adult Pediatric
Select “Calibrate O2 sensor” by the Bypass system test

ComWheel and confirm the selection. Calibrate O2 sensor
Exit

9 Maintenance
The system prompts with the following screen.
The calibration
procedure takes up to Centiva/5
60 secs. The remaining
Oxygen sensor calibration
test time counts down
Calibration time 42 s
on the screen. O2-Concentration 21 %
Message box
Stop
The system flows approx. 10 L/min in the inspiratory line to stabilize the
O2 sensor at 100% O2. The measured O2 concentration is displayed on
the screen.
If problems occur during calibration, a message will be displayed in the

message box. For details refer to section 8 “Alarms and messages”.
When calibration is
successfully completed Centiva/5
the system prompts Oxygen sensor calibration
with a screen message Calibration succesfully finished
and returns to the
power-up test screen.
9.2.2 Stop calibration Pushing the “Stop” button during the calibration procedure ends the
calibration. The system returns to the power-up test screen and uses
the previous calibration data.

9 Maintenance
9.3 Expiration valve
The Centiva/5 uses a removable expiration valve assembly for easy

cleaning and maintenance. The valve assembly consists of three
components,
• the valve block
• the PEEP membrane assembly
• the membrane plate
CAUTION Handle the silicone PEEP membrane assembly carefully.

To ensure the product’s performance and accuracy inspect the
expiration valve and it’s components for distortion, deterioration
and/or cracks and replace, if necessary.
9.3.1 Remove expiration valve Turn ON the Centiva/5 and wait for the power-up test to finish.
assembly
After having successfully passed the power-up test and the
system test, the system test menu can be activated by
pressing the menu button.

selection of certain
System Test Rev. x.nn
service functions .
Selecting “Exit” closes
Complete system set up, seal Y-piece
the system test menu Start system test by pressing <Enter>

Bypass system test
without any activity. Unlock expiration valve
Calibrate O2 sensor
Exit
Adult Pediatric
Select “Unlock expiration valve” by the Bypass system test

ComWheel and confirm the selection. Calibrate O2 sensor
Exit
This process works with main power supply and with internal back-up
battery supply as well.

9 Maintenance
The Centiva/5 prompts with the following screen :
The system unlocks

the expiration valve Centiva/5
assembly and the System test Rev. x.nn
assembly now can be Expiration valve unlocked
removed from the Ready to be removed from device
device.
The operator can now

remove the valve
assembly from the system
by moving it to the left
side.

9 Maintenance
9.3.2 Replace components The expiration valve is easy to take apart. Remove the stainless steel
plate and then remove the PEEP membrane assembly.
Inspect the stainless steel plate

(A) and the PEEP membrane A
assembly (B) for distortion,
deterioration and/or cracks and B
Inspect the block, expiratory
22mm connector (D) and sealer
port (C) for distortion,
C D
In case the Centiva/5 reports problems with the expiratory flow
measurement during a system test, inspect the o-ring of the flow
measurement port (H) for distortion, deterioration and/or cracks and
replace, if necessary. Lubricate this o-ring (H), when dry.
If a dirty or blocked flow screen is the reason for an expiratory flow
measurement problem, at first verify proper cleaning according to
chapter 7. 4. If this does not solve the problem, the flow screen needs
to be replaced. To replace the flow screen (E) unscrew the flow screen
retainer (F) by using a non-sharp instrument. Then replace the flow
screen (E) and screw on the retainer again.
F E C D B A
CAUTION Handle carefully the silicone PEEP membrane assembly and the
flow screen.

9 Maintenance
9.3.3 Reassembly Insert the PEEP membrane assembly (B) into the block with the note
“TOP” facing you.
Verify the stainless plate (A) is

positioned on top of the A
membrane assembly.
B
Check for proper seating of all
components prior to reinsertion
into the system’s locking device.
The PEEP membrane assembly 3

comes completely assembled.
In the event the PEEP membrane 2
assembly comes apart or parts of
the assembly need replacement 1
push the nipple of the PEEP TOP
seal membrane (1) through the
PEEP PSU plate (2) (beveled edge
up) and finally through the PEEP
silicone membrane (3).
When inserting the PEEP membrane assembly into the expiration

valve block make sure the silicone membrane faces the valve seat
and verify the proper assembly by looking for the “TOP” mark on top of
the PEEP membrane assembly after insertion.
CAUTION Handle carefully the silicone PEEP membrane assembly.

9 Maintenance
9.3.4 Reinsertion of Slide the entire assembly into the expiration valve locking mechanism
expiration valve assembly slot with the expiration port to the front.
The expiration valve

assembly should be
inserted smoothly .
Do not try to overcome a high resistance or try to force the assembly

back into the slot. If problems occur with reinsertion check for proper
assembly of the expiration valve.
The Centiva/5 will automatically recognize the insertion and lock the
expiratory valve assembly in, if powered by a main supply. After
proper locking the system performs a power-up test to verify proper
operation.
Upon successful test

the following screen is Centiva/5
prompted and asks the System test Rev. x.nn
user to start the system
Complete system set up, seal y-piece
test.
Start system test <Enter>
Adult Pediatric
In case reinsertion was

Special notice performed with the Centiva/5 powered by the internal back-up
battery, the valve assembly will not lock. Locking will be performed the
next time the Centiva/5 is turned on with main power supply and after
passing the power-up test.

9 Maintenance
9.4 Additional maintenance
The following maintenance procedures are subject to be performed by

authorized service personal only. Special service instruction is
mandatory to perform these maintenance procedures.
9.4.1 Every twelve (12) Perform the following every twelve months:
months 1) Remove all user level breathing system assemblies and
components from the breathing system.
2) Remove the expiration valve form the main engine.
3) Open the main engine according to service manual.
4) Inspect the Centiva /5 ICU Ventilator and the removed
components for distortion, deterioration and/or cracks .
5) Inspect and replace, if necessary, the expiration valve
components according to service manual.
6) Replace the O2 sensor, if necessary, according to service
manual.
7) Replace O-ring on NIST connector (if applicable) at supply hose
for AIR and O2.
8) Perform calibration of sensors for AIR flow, O2 Flow, Expiration
flow, Airway pressure and of over pressure relief valve and battery
charging voltage according to service manual.
9) Reassemble and close the main engine.
10) Perform the Post-service checkout according to service manual.
11) Perform the electrical safety test for
• Ground resistance (< 0.2 Ω )
• Leakage current (< 500 uA)
• Insulation resistance (> 10 MΩ)
9.4.2 Every twenty four (24) In addition to the 12 month requirements, perform the following every
months twenty-four months:
1) Replace the internal back up battery according to service

manual.
2) Replace the free breathing valve, if necessary, according to
service manual.

10 Technical data
In this section 10.1 General 10-2

10.2 Supplies 10-3
10.3 Ventilator characteristics 10-4
10.4 Controls and ranges 10-5
10.5 Special functions 10-8
10.6 Measurement functions 10-9
10.7 Monitoring functions 10-10
10.8 Control panel 10-13

10 Technical data
10.1 General
Application Intended use: ventilation of patients

Area: intensive care, recovery room,
intra clinical patient relocation,
general ventilation
Use in: stationary, transport
Patient groups: adults and children with
5 kg body weight and up
Physical dimensions Width * depth * height: 250 X 260 X 210 mm

(10.3 X 11.4 X 8.3 in)
Volume, net: 13,6 dm3
Minimum ground space: 6,5 dm 2
Weight, net: 13 kg (28.7 lbs)
Weight, incl. trolley: 27 kg (55.1 lbs)
Operation Structure: menu operated

Principle: select - adjust - confirm
Operation control: Soft keys, ComWheel
Menu language: English, others on request
Environmental conditions During operation

Temperature: 10 to 35 °C
Atmospheric pressure range: 600 to1060 hPa
Humidity range: 0 to 90 %, (non-condensing)
Noise level: ≤ 43 db(A)
During storage and transport

Temperature: - 20 to 50 °C
Atmospheric pressure range: 500 to 1060 hPa
Humidity range: 0 to 99 %, (non-condensing)
Electromagnetic Tested to comply with EN 60601-1-2, according to

compatibility directive 89/336/EEC
Classification Class: II b, according to directive

93/42/EEC, Annex IX, Rule 9
Protection class: Type B

10 Technical data
10.2 Supplies
Electrical supply Line supply:

AC supply voltage range: 207 to 253 V AC, 50/60 Hz
98 to 132 V AC, 50/60 Hz
Power consumption: < 50 W
Alternate electrical supply:

DC supply voltage range: 22,5 to 28 V DC
Maximum current: 3 A DC
Internal back-up battery supply:

Battery: built-in
Type: sealed lead acid
Turn ON: automatic upon loss of main supply
Battery back-up time: ≥ 30 min, (battery fully charged)
Grounding: standard ground stud
Gas supply Oxygen supply, (O2) :

Pressure range: 280 to 600 kPa, (40 to 80 PSI)
Quality: medical grade oxygen,
dry, oil and particle free
Air supply, (AIR):

Pressure range: 280 to 600 kPa, (40 to 80 PSI)
Quality: medical grade AIR,
dry, oil and particle free
Single gas operation:

Selectable: in system test
Automatic: upon loss of one gas
Gas type: similar for both, O2 and AIR

10 Technical data
10.3 Ventilator characteristics
Ventilator - Base Ventilation modes: VCV, PLV, PCV, SIMV-VC,

SIMV-VC/PSV, Bi-Level,
Bi-Level/PSV, APRV, CPAP,
CPAP/PSV, CPAP/Apnea
Operating principle: time controlled,
volume constant,
pressure cycled
Trigger system: flow trigger
Safety features Emergency free breathing valve: allows patient’s spontaneous

breathing with room air upon total
loss of gas supply
Over pressure relief valve, releases pressure in the breathing

Active circuit if Ppeak > (Pmax + 2 cmH2O)
Over pressure relief valve, limits maximum system pressure in

Passive the breathing circuit to 75 ± 2cmH2O
Characteristics Max. inspiratory pressure: 10 to 70 cmH2O

Max. inspiration flow: 120 L/min *
Device compliance: < 2.0 mL/cmH2O **
Inspiratory resistance: < 1.5 cmH2O/L/s **
Expiratory resistance: < 2.5 cmH2O/L/s **
Compensation: automatic for compliance and

resistance of breathing circuit used
during System Test
Note * 120L/min is the sustained

maximum inspiratory flow. The
system can deliver higher flows (up
to ∼ 180 L/min) for short periods of
time.
** with breathing circuit for adult,

2x22mm, 1,6 m length

10 Technical data
10.4 Controls and ranges
VCV Mode Soft keys

FiO2: 21 to 100 % O2
Rate: 4 to 100 1/min
I:E ratio: 4:1 to 1:9.9
Vt: 20 to 2,000 mL
P limit: 10 to 60 cmH2O
PEEP: OFF to 35 cmH2O
I- Flow: 2 to 99.9 L/min
Parameter menu
ByFlow: 3.0 to 30 L/min
Buzzer: 20 to 100 %
SIMV-VC Mode Soft keys

FiO2: 21 to 100 % O2
I:E ratio: 4:1 to 1:9.9
Vt: 20 to 2,000 mL
P limit: 10 to 60 cmH2O
PS: 0 to 59 cmH2O
Parameter menu
I-Flow: 2 to 99,9 L/min
PS ramp: 0,2 to 0,5 sec
Trigg.: 0.5 to 20 L/min
ByFlow: 3 to 30 L/min
Time window: 20 to 90 % of expiration time
PS end flow: 10 to 60 % of peak PS flow
Buzzer: 20 to 100 %

10 Technical data
Bi-Level Mode Soft keys

FiO2: 21 to 100 % O2
I:E ratio: 4:1 to 1:9.9
APRV I:E ratio: 9.9 :1 to 4:1
Ramp: 0,1 to 3 sec
P insp.: 1 to 59 cmH2O
PS: 0 to 59 cmH2O
Parameter menu
Buzzer: 20 to 100 %
CPAP/PSV Mode Soft keys

FiO2: 21 to 100 % O2
Ramp (PS): 0,1 to 3 sec
PEEP (CPAP): OFF to 35 cmH2O
PS: 0 to 59 cmH2O
Parameter menu
Buzzer: 20 to 100 %

10 Technical data
CPAP/Apnea Mode CPAP/PSV Mode with Bi-Level back-up mode, in case of apnea
CPAP/PSV Mode Soft keys

FiO2: 21 to 100 % O2
Ramp (PS): 0,1 to 3 sec
PEEP (CPAP): OFF to 35 cmH2O
PS: 0 to 59 cmH2O
Parameter menu
Buzzer: 20 to 100 %
Bi-Level back-up mode Soft keys

FiO2: 21 to 100 % O2
I:E ratio: 4:1 to 1:9.9
APRV I:E ratio: 9.9:1 to 4:1
Ramp: 0,1 to 3 sec
P insp.: 1 to 59 cmH2O
PS: 0 to 59 cmH2O
Parameter menu
Buzzer: 20 to 100 %

10 Technical data
10.5 Special functions
Airway Resistance Type of compensation: electronic tube compensation

Compensation (ARC) For: endotracheal and tracheal tubes
Tube diameter: 4 to 10 mm, select from database
Way of compensation: inspiratory, pressure increase
expiratory, pressure release below
PEEP, but above 0 cmH2O
Level of compensation 25 to 100 %
Automatic Patient Detection Patient reconnection: automatic detection in

(APD) standby mode
Type of detection: I and E flow difference to ByFlow
Automatic Suction Routine Program routine: automatic

(ASR) Pre-oxygenation: ≤ 2 min with 100% O2
Standby pause: ≤ 2 min with APD
Post-oxygenation: ≤ 2 min with 100% O2
Open the circuit: pressure relieved
Detection of disconnection: automatic
Detection of reconnection: automatic
Nebulizer (NEB) Program routine: automatic

Nebulizer time: fixed, 30 min
Nebulizer flow: Inspiratory synchronized,
compensated
Nebulizer pressure range: 1.6 to 2.0 bar at flow range
Nebulizer flow range: 4 to 12 l/min,
flow test option in system test
Non - Invasive Ventilation Leakage compensation: 0 to 50 % of the leak

(NIV) Mask ventilation: yes
Compensation: automatic
Show level of leakage: via leakage alarm parameter
O2 calibration (OVC) Program routine: semi - automatic

Calibration: during any ventilation mode
Calibration time: 5 min

10 Technical data
10.6 Measurement functions
Airway pressure Range: -9 to +90 cmH2O

Resolution: 1 cmH2O
Accuracy: ± (0.5 cmH2O + 2%)
Ppeak: maximum pressure value within
one breath
Pmin : minimum pressure value within
one breath
O2 concentration Range: 15 to 100 Vol%

Resolution: 1 Vol%
Accuracy: ± 3 Vol%
O2-I: inspiratory O2 concentration
Flow Range: -120 to +140 L/min
Tidal volume Range: 0 to 2.500 ml

Resolution: 1 ml
Accuracy: ± (10 ml +10%) @ 20 to 100 ml
± (10 ml + 5%) @ 110 to 300 ml
+5% @ 310 to 2,500 ml
Vt: expiratory tidal volume
Minute volume Range: 0 to 99 L/min

Resolution: 0,1 L
Accuracy: ± (10 ml + 10%)
MV E: expiratory minute volume
over one minute
Rate Range: 0 to 200 breaths per minute

Resolution: 1 breath per minute
Accuracy: ± 1 breath per minute
Rate: sum of mechanical and
spontaneous breaths over one
minute

10 Technical data
10.7 Monitoring functions
Expiratory minute volume Upper alarm limit: MV max

Alarm upper limit: MV E was higher than MV max
Adjustment range: 50 to 0,5 L/min
Lower alarm limit: MV min

Alarm lower limit: MV E was lower than MV min
Adjustment range: 0,5 to 50 L/min
Overlapping protection: MV max > MV min

MV min < MV max
Airway pressure VCV, SIMV-VC mode

Upper alarm limit, No. 1: Plimit
Alarm upper limit: Ppeak was higher than Plimit, two
times in a row
Adjustment range: 10 to 60 cmH2O
All ventilation modes

Upper alarm limit, No. 2: Pmax
Alarm upper limit: Ppeak was higher than Pmax
Adjustment range: 12 to 70 cmH2O
Leakage Upper alarm limit: Leakage (Inspiratory volume

minus expiratory volume)
Alarm upper limit: Leakage was higher than set limit
Adjustment range: 5 to 95 %
Apnea time Upper alarm limit: Apnea time (time without breathing
activity)
Alarm upper limit: no breathing activity in set apnea
time
Adjustment range: 10 to 60 secs

10 Technical data
Rate Upper alarm limit: Rate max

Alarm upper limit: Rate was higher than Rate max
Adjustment range: 200 to 3 breaths per minute
Lower alarm limit: Rate min

Alarm lower limit: Rate was lower than Rate min
Adjustment range: 2 to 199 breaths per minute
Overlapping protection: Rate max > Rate min

Rate min < Rate max
Inspiratory O2 concentration Upper alarm limit: O2-I max

Alarm upper limit: O2-I was higher than O2-I max
Adjustment range: automatic via set FiO2 setting
Range:
FiO2 = 21 to 50 Vol% O2-I max = FiO2 + 5 Vol%
FiO2 = 100 Vol% O2-I max = 110 Vol%
Lower alarm limit: O2-I min

Alarm lower limit: O2-I was lower than O2-I min
Adjustment range: automatic via set FiO2 setting
Range:
FiO2 = 21 to 50 Vol% O2-I min = 18 Vol% or
FiO2 - 5 Vol%
FiO2 = 51 to 60 Vol% O2-I min = FiO2 - 6 Vol%
FiO2 = 100 Vol% O2-I min = 90 Vol%
Overlapping protection: O2-I max > O2-I min

O2-I min < O2-I max

10 Technical data
Manual setting Set alarm limits: via menu “alarm limits”

Type of setting: independent for each alarm value
Setting for : MV max
MV min
Plimit
Pmax
Leakage
Apnea time
Rate max
Rate min
Automatic setting Set alarm limits: via function “AUTOSET”

Type of setting: automatic for all values, oriented
on the according measured
parameters (mp)
Setting for: MV max
MV min
Plimit
Pmax
Rate max
Rate min
Serial data transfer Hardware connection: D-Sub 9, RS 232 C

DIS 7900 Non Aestiva
Software protocol: Ohmeda Com 1.0 serial protocol
Transferred data: Ventilator settings
Alarm settings
Measured data, numerical
Alarms activated
Pressure and flow waveform

10 Technical data
10.8 Control panel
General Type of screen: color LCD with back light

Screen size: 6,5” / 16,5 cm
Control system: Soft keys
menu button
alarm silence button
ComWheel
Mounting: detachable,
adjustable to best viewing angle,
remote control
Screen presentation Waveforms in screen: two at a time

Waveform parameters: Flow and airway pressure over time
Waveforms: synchronous
Waveform scaling: automatic for optimized size
Setting values: permanently presented
Measurement values: permanently presented
Alarm limit values: permanently presented
Status information: permanently presented
Audible Alarm Alarm volume: adjustable

Range: 20% to 100% of total volume

10 Technical data
Notes

11 Parts list
In this section 11.1 Spare parts 11-2

11.2 Accessories 11-2

11 Parts list
11.1 Spare parts
Line supply fuses Product Order number

Fuse 0.8 A, slow blow, 5x20 mm, 230 V EF-761079
Fuse 1.6 A, slow blow, 5x20 mm, 115 V EF-761086
Control panel Product Order number

Com wheel button 898794
Expiration valve Product Order number

Expiration valve assembly, complete BM-352385
PEEP membrane assembly, complete BM-352386
PEEP TOP seal membrane CM-525531
PEEP PSU plate CM-510130
PEEP silicone membrane CM-510129
PEEP maintenance kit MA-640000
Stainless steel plate for PEEP membrane CM-510130
O-ring for flow measurement port DO-628204
Flow screen CM-523034
Retainer, flow screen CM-510133
11.2 Accessories Refer to separate accessory list

Warranty
This Product is sold by Datex-Ohmeda under the warranties set forth in

the following paragraphs. Such warranties are extended only with
respect to the purchase of this Product directly from Datex-Ohmeda or
Datex-Ohmeda’s Authorized Dealers as new merchandise and are
extended to the Buyer thereof, other than for the purpose of resale.
For a period of twelve (12) months from the date of original delivery to
Buyer or to Buyer’s order, but in no event for a period of more than two
years from the date of original delivery by Datex-Ohmeda to a Datex-
Ohmeda Authorized Dealer, this Product, other than its expendable
parts, is warranted against functional defects in materials and
workmanship and to conform to the description of the Product
contained in this operation manual and accompanying labels and/or
inserts, provided that the same is properly operated under the
conditions of normal use, that regular periodic maintenance and
service is performed and that replacements and repairs are made in
accordance with the instructions provided. This same warranty is made
for a period of thirty (30) days with respect to expendable parts. The
foregoing warranties shall not apply if the Product has been repaired
other than by Datex-Ohmeda or in accordance with written instructions
provided by Datex-Ohmeda, or altered by anyone other than Datex-
Ohmeda, or if the Product has been subject to abuse, misuse,
negligence, or accident.
Datex-Ohmeda’s sole and exclusive obligation and Buyer’s sole and

exclusive remedy under the above warranties is limited to repairing and
replacing, free of charge, at Datex-Ohmeda’s option, a Product, which
is telephonically reported to the nearest Datex-Ohmeda Field Service
Support Center and which, if so advised by Datex-Ohmeda, is thereafter
returned with a statement of the observed deficiency, not later than
seven (7) days after the expiration date of the applicable warranty, to
the Datex-Ohmeda service and Distribution Center during normal
business hours, transportation charges prepaid, and which, upon
Datex-Ohmeda’s examination, is found not to conform with above
warranties. Datex-Ohmeda shall not be otherwise liable for any
damages including but not limited to incidental damages,
consequential damages, or special damages.
There are no express or implied warranties which extend beyond the

warranties hereinabove set forth. Datex-Ohmeda makes no warranty of
merchantability or fitness for a particular purpose with respect to the
product or parts thereof.
W-1
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Greece
Tel +30 10 962 5136-7
Fax +30 10 962 3687 Middle East/Africa
Datex-Ohmeda
Regional Head Office
PO Box 70071
GR-16610 Glyfada - Athens
Greece
Tel +30 10 962 5136-7
Fax +30 10 962 3687
The addresses listed on this cover are current as of 6/03. For any location changes,
please visit our website at www.datex-ohmeda.com and click on the Contacts button.
Datex-Ohmeda, Inc. Manufactured by: Salvia Lifetec Gmbh & Co KG Centiva/5

PO Box 7550 Niederhöchstädter Str. 62 UR Manual, English
Madison WI 53707-7550 USA 61476 Kronberg Germany CM-920041, Rev 2.22
Tel 1 608 221 1551 Tel 49 61 7393330 Printed in Germany
Fax 1 608 222 9147 Fax 49 61 73933329 © TIM Gmbh, all rights reserved
www.datex-ohmeda.com 0123 www.salvia-lifetec.de www.tim-gmbh.de

Datex-Ohmeda Centiva-5 - User Manual

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Centiva/5

User’s Reference Manual

This Product will perform in conformity with the description thereof

Datex-Ohmeda products have unit serial numbers with coded logic

This alpha character indicates the year of product

URM Centiva/5, CM-920041, rev. 2.22  TIM GmbH

1 Introduction 1.1 How to use this manual 1-2

2 Safety 2.1 Safety 2-2

3 General description 3.1 General description 3-2

4 Concept of operation 4.1 Concept of operation 4-2

URM Centiva/5, CM-920041, rev. 2.22 0-1

4 Concept of operation 4.1.4 Timing parameters 4-7

5 Preparation 5.1 Electrical supply 5-2

0-2 URM Centiva/5, CM-920041, rev. 2.22

6 Operation 6.1 Adjust ventilation modes 6-2

7 Cleaning and Sterilization 7.1 General advice 7-2

URM Centiva/5, CM-920041, rev. 2.22, 0-3

8 Alarms and messages 8.1 Alarm modality 8-2

9 Maintenance 9.1 General 9-2

10 Technical data 10.1 General 10-2

11 Parts list 11.1 Spare parts 11-2

0-4 URM Centiva/5, CM-920041, rev. 2.22

In this section 1.1 How to use this manual 1-2

URM Centiva/5, CM-920041, rev. 2.22 1-1

1.1 How to use this manual

This manual describes the operation of the

Centiva/5 ICU ventilator

The Centiva/5 ICU ventilator may be used together with additional

1-2 URM Centiva/5, CM-920041, rev. 2.22

1.2 Symbols used in this manual or on the equipment

Warnings and Cautions tell you about dangerous conditions

CAUTION Cautions indicate a condition that can cause damage to the

Alarm silence touch key

Menu touch key

Left turn ComWheel to decrease value

Right turn ComWheel to increase value

Rotate ComWheel to change value

Push ComWheel to confirm selection (ENTER)

URM Centiva/5, CM-920041, rev. 2.22 1-3

Protective earth ground

Input (Expiratory port)

Output (Inspiratory port)

Attention, refer to product instructions, EN/IEC 60601-1

10101 Serial data transfer connection

Nebulizer gas supply

DC external power supply

1-4 URM Centiva/5, CM-920041, rev. 2.22

1.3 Abbreviations used in this manual or on the equipment

Vent. mode Ventilation mode

APD Automatic patient detection

Pmax Safety pressure setting

Rate Breaths per minute

Vt Tidal volume setting

URM Centiva/5, CM-920041, rev. 2.22 1-5

Fi-O2 Inspiratory O2 concentration setting

I On (power), line supply

Ref Stock number

O2 40 … 80 PSI O2 gas supply input with a pressure range of 40 … 80 PSI

24V/3A DC DC supply input with 24 V and a maximum current of 3 A

1-6 URM Centiva/5, CM-920041, rev. 2.22

In this section 2.1 Safety 2-2

URM Centiva/5, CM-920041, rev. 2.22 2-1

Reference This manual describes the operation of the

URM Centiva/5, CM-920041, rev. 2.22