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Nervous System
- capable of receiving and processing information, making decisions, and relaying the
required command for action
- allows organisms to sense, organize, and react to information in the environment
2. Neurons
- serve as interconnected information processors that are essential for all of the tasks of
the nervous system
- central building blocks of the nervous system
- there are 100 billion neurons
- like cells, it is composed of different parts each serving a specific function
- the outer surface is semi-permeable
- main function
Parts of a neuron
NOTE: At the end of each AXON, there are Terminal Buttons that contain
synaptic vesicles that house neurotransmitters.
d. MYELIN SHEATH covers and protects the axons and is responsible for the rate of
transmission of signaled stimulus. It acts like “bumps”.
e. NODES serve as break on the momentum of speed; interruption on the myelin sheath that
control the speed of transmission of information or stimulus on the neurons. It acts like
“oil”.
f. SYNAPSE is a very small space between two neurons and is an important site where
communication between neurons occurs.
g. RECEPTORS are proteins on the cell surface where neurotransmitters attach, vary in
shape, with different shapes “matching” different neurotransmitters.
Neurotransmitters are chemical substances released by one neuron through the synapse and
affecting another neuron; generated excitatory current when the neuron’s charge increases upon
connection through synapse and inhibitory current for decreasing charge; responsible for:
1. Sensation
2. Perception
3. Cognitive
4. Motor behavior
Ex.
HIGH in
A depressed MOREPENEPHRINE
A happy person is & EPENEPHRINE
person is LOW in (Stressed or
HIGH in SEROTONIN fight/flight
People in love are HIGH in
SEROTONIN and situation)
SEROTONIN, DOPAMINE
DOPAMINE.
and OXYTOCIN.
ACETYLCHOLINE
Primary Function: Muscle control, memory formation,
sensory response. Excitatory.
Locations: Neuromuscular junctions, CNS
Receptors: Nicotinic muscarinic
Definition: One of the most common very well studied. A
major player in memory. Imbalances cause twitching or
paralysis.
- Increases arousal and enhance cognition
SEROTONIN
Primary Function: Intestinal movement control, mood
regulation, appetite, sleep, muscle control
DOPAMINE
Primary Function: Reward pathways, cognition, voluntary
motion
Locations: Hypothalamus
Receptors: D1, D2, D3, D4, D5
Definition: Imbalances cause Parkinson. Cocaine and
opiates have a significant effect on its release.
- Mood, sleep, learning, increase pleasure, sometime
suppress appetite
NOREPINEPHRINE
Primary Function: Fight or Flight response (increased heart rate, increased glucose in
bloodstream, increased oxygen to brain and muscles)
Locations: Adrenal medulla
Receptors: Adrenergic
Definition: Produced from Dopamine in the adrenal glands (on kidney
L-DOPA
Primary Function: Precursor to dopamine
Locations: Hypothalamus
Receptors: N/A
Definition: Able to cross the blood-brain barrier making it an
excellent pharmaceutical for treatment of Parkinson or depression
TRYPTOPHAN
Primary Function: Precursor to Serotonin
Locations: Blood
Receptors: N/A
Definition: Essential amino acid
GLYCINE
Primary Function: Inhibits signals
Locations: Spinal cord, Brainstem
Receptors: NMDA
Definition: Amino acid
TYRAMINE
Primary Function: Blood Pressure regulation
Locations: CNS, Kidney
Receptors: TA1
Definition: Amino acid, minor neurotransmitter that is
largely not understood
GLUTAMATE
Primary Function: Long-term potentiation, memory
Locations: CNS, PNS
Receptors: NMDA, others
Definition: Most common
BETA-ENDORPHIN
Primary Function: Plain, Pleasure
Effect: decreased anxiety / tension
OXYTOCIN
It is released into the bloodstream as a hormone in response to sexual activity and during
labor. It is also associated with empathy, trust, sexual activity, and relationship-building. It is
sometimes referred to as the “love hormone,” because levels of oxytocin increase during
hugging and orgasm
Central Nervous System
- comprised of the brain and spinal cord
- main function: the integration and processing of sensory information
- synthesizes sensory input to compute an appropriate motor response or output
SPINAL CORD
BRAIN
a. Forebrain - is the largest and most complex part of the brain and is responsible for
cognition, motivation and action
Forehead - frontal
4. Hypothalamus - controls body temperature, thirst, appetite, sleep patterns, and other
processes in our bodies that happen automatically. It triggers the pituitary gland to
release hormones.
b. Midbrain - located underneath the middle of the forebrain, acts as a master coordinator
for all the messages going in and out of the brain to the spinal cord. It serves primarily as
a reflex center for orienting the eye and ears. It is also serves as a passageway for the left
and right hemispheres of the brain described like a “security guard”.
c. Hindbrain - sits underneath the back end of the cerebrum, and it consists of the
cerebellum, pons, and medulla. It performs routine, housekeeping functions that keep the
body working properly.
1. Cerebellum - also called the “little brain” because it looks like a small version of the
cerebrum; is responsible for balance, movement, and coordination.
2. Brain Stem - the pons and the medulla, along with the midbrain; takes in, sends out,
and coordinates all of the brain’s messages; also controls many of the body’s
automatic functions, like breathing, heart rate, blood pressure, swallowing, digestion,
and blinking
6. Occipital
Lobe -
responsible for visual
Peripheral Nervous System – made up of thick bundles of axons called nerves, carrying
messages back and forth between the CNS and the muscles, organs, and senses in the periphery
of the body
Parasympathetic Nervous System – associated with returning the body to routine, day-
to-day operation
Autonomic Nervous System – controls our internal
organs and glands and is generally considered to be outside
the realm of voluntary control. It can be further subdivided
into the Sympathetic and Parasympathetic divisions:
Endocrine System – consists of a series of glands that produce chemical substances known
as hormones
f. Pancreas - an internal organ that secretes hormones that regulate blood sugar levels:
insulin and glucagon.
h. Pineal - its hormone (melatonin) helps the pituitary gland in regulating its function;
supports the pituitary gland