U-1, Pe-1, Carewell Pharma

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Carewell Pharma
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Unuk-Ist Dcte
flo of uids
a
Recducion
rm
Size
Separction
C Siz
Chaph.Lst
ha
lP
uhsjanu which auN
alli o l
(Slud MACMt t8hapl doL uaE chano
el
iguid MAUuemt ane dformaien in kaps

w
re
Liqud 4 Gas au-ids

Ca
Hud prelue
K pcsu which apP
-tL-id
Aso kxosn_ HydroAtahc presur
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Carewell Pharma
Preksw -6rcQ
fAHea A
(M
a
A
rm
xArxg
ha
lP
(Mauo AAgher)P_
IF diuces
a ch_u
USLo
MeaA preue diHerenco
el
yu emaMbuttr
w
Sinplu
Maunamiu
re
Muomurer
Simpl moMoer
Ca
Tus
which
at tos TmaMour
phee a ay p0iu n_ a tuba ek-
U-tuhe
MaUDmLty

Page 3 of 17
Carewell Pharma
Page
Date
u)Dfetal Manomuty Thest a honManomuurt

whith Uud o
measu
_phEAAu cluffetn w ony u0 gau
a
gudh
dilfercnhial mamomitr
e V- tuh
rm
Phf
ha 1
lP
el
h t 4gh)_
w
-P Ih.
re
Ca
shaduy16u) luauid fMA Conutauty_
tuabukut foy Not in mfaujt

Page 4 of 17
Carewell Pharma
Page
Thute
/
Rynold umblr
u 2ahoasf h
tHnolds
incutiaHoncA which inceaa_Dtlneldu
a
na.) uiscaus =fcucs_[whith suH)
rm
Re =1uhal -tart
Viscous oI
d
whwul cdunsi ha
-fluid
lP
U velocibspred)
d= duamuleyof_pip
el
tqive tha fHe cody 0

ubulet
w
Re(loto thn-flo U Atady

re
ubulnk
So palcdictHu matunt
Ca
tor -1ui(fles).
alko WLd
Ledimuntalhm
o Atudy -lh
i

Page 5 of 17
Carewell Pharma
Puge:
Date: /
Rernaulii-neore M
Th otal mechanita enna
enmgy
Hh_movin9- ud tospaising =h
a
gruitrihional paieuhaleVnug of_elfvahin
enug astbtlattdwlh -uidpKAA
rm
and Einihc enngy O lud MDhon_
Demains_Canstout.
Eini
eungy
ha
P+YPN+Pgh = comatumt
lP
hul,
PpHMMA Exeakd by i fuds
V=_ Veloutyof tuHuid
el
P_denut ef -tu Huid

h he1ghe Of t (Ontainsr
pu.
w
8-
re
Ca
L+Bgh= gh

Page 6 of 17
Carewell Pharma
Poge
Datec:
/
Som Lnugy loie duing.
-10
a
riuhona 18 Duing -[Louw
-uid
rm
pip 0 idion_appy
onHuid by- wall_of pip
and t_opp0A nHi0u 0nd duuing
DAA
ha
Aomu
lP
HagunPamdu e
el
P 32 LuH
w
re
BR(fithon Jos
Lngh ofP
Hlouhy o-luid
Ca
-D Diamulcr

Page 7 of 17
Carewell Pharma
Pag
Date: /
incaA ML
PLRAL SizL un u anA
Lhaugus_oE Son elbcik duu o wu
a
Pniugulo oCUK
rm
ha
lP
24
el
Cowspicha leld whtn wt ductasu iz of

PApelouhy IncKAMR enAy loM
w
A
re
Ca
AH

Page 8 of 17
Carewell Pharma
|Page:
Date:
)titting les hn w bndth

hn
ud h dinechm chang _ Qud
o diztthon OAL SOm
a
HOLChnQA
10
rm
F
ha
lP
Ratr af i0 s Auid
el
Oifiu Mtr
Ventuy milu. Dizect mHhod
)_utat ubeMIU
w
V Rotamuler
re
Oriki_Mttr
Outiu (hah)
Ca
The pzinüplu bausd On Burnaulli tuortm

-An fiu utr a duuiu luith wda
outi
ratc-ousApuduelai
hrargh plates

Page 9 of 17
Carewell Pharma
eape Date
Couaueriom
a
rm
Dufi
mavomuttr
ha
An-pL daffeu
Hcmula+ Ho= 2. AH
lP
we, Ha velocu ofuud
Co lonatant
Qrauutohon fo
el
AH= pHSU dufferenu

So, Conind n LpHeBm ditftexnu)braqh
w
h Manout wkih ttaad on

PLPA
re
Pat th yalu of pheiu ditent oM

ufi
mtu omul0 w
ind aut tu
uel0u of fluid
Ca
Usu Usd to mo elocui of u

Advutogu O Sipla to w L COsupicially on langa
3No udto ecalircuhion Azu
Digadautaq O Maeanu poplan Poo Poo aracy

Page 10 of 17
Carewell Pharma
Venthui meler, Pitot tuk muler Rotamuter
Neutu MelkL
a
rm
uud to
ratt of fHow Liquid (spud, veloi)in
a pp
ha
lP
inúpl- T basd on thu painipl
of Beunoulli's tmuom.
el
Vouh utr Cous of two tappud sucion
in tu Ppulin wih a qrodual

w
Conspichion (tnrdat) at
it uhe.
re
wun-uid u passud hrough entuu mut,

th chang n PusuL had (aH)
Ca
aud incas veloty duu to Conspictim

OF veuul mili (AcC. to Bunoulli.)
0y
Oy tis fomula
Cu J29.AH

Page 11 of 17
Carewell Pharma
we Can
ensi -fiud ou + vebi of ftuid.
Coustruchion
VENTVRIMETERR
Short tapuud
Secton
a
ler
ucim
Oulkt
T Thoot of Stcim
rm
Upsteam
. vetui
Downstam
ha
lP
Long tappued
Suhion
el
Manome
w
Tt Consists of tuo tapad

Of Section e insurtd in a
re
piplin wih (onstrichion ar mutr cet

T upsteum CoL normally sho tan tu
Ca
downsteam
T tapurs SMOoth and gradual
manomr is at poin A 4
Conneced
Meas Phessn duffeunu

Page 12 of 17
Carewell Pharma
Working
ventuy mtl
firsty is imeled butween Ppalin
Whun ftuid i pasud hrough vexhui mute
a
th dotiky OF
-ftuid incHaud ot
rm
to COMstaicion
thu Hhroaf,du
Thi Heult in decreaud pRSSL in tn
o
ha
up-steam CoML thange in PALsSUL had) .
which
-futu Calculakd trough Manome
lP
Now
UG4g.aH
el
wwA,
Uv veloihy of fluid thiouh
w
ventuamukn
V Coefftii eur
of-u vextui mr
re
DH PressL ad difeuntu
Ca
NOW, pu valu of H uolich i
MLOsL Manomii) in Mil e

aud find tu veloi of fAud

Page 13 of 17
Carewell Pharma
UsuA is (oMmonly uud ou üquid (wa) nd
also for
eitot Tub Muher
-u rar
a
usd measul
o (spud, velocihy)/veloiky huad.
rm
Liquid
frinúpl
ha
T Measu ta velou at ont poin onlu
T basad on h Priniplu of Beanoulli's

lP
heorem
Wun F insued ino tu Conl ofF pip
of tow
el
velouky i inceased at tha

poin, an chang in Pus hiad.
w
which fut Colculahed hrough mono muteL

re
tun pur thiuunlu in aud ind out

Valu of velocity iad
Ca
N
Vachenl=(vJ2q aH
wwL
Var veloa of ftuid (velel had)
Cv tfrient of twbu
putok
DH= wmL huad diffeun

Page 14 of 17
Carewell Pharma
Cowsuchiom - PITOT TUBE
Deun steam
Vpspearn
a
2
rm
ilor tuba ha Manomuer
lP
known insuion muler.
Hso
el
Siz SMal componudto pip

Ppendicular to tu fow
w
O tulee
diection Omd th otu tubL
re
Conecttd panallel dixcin of fHou

to
Ca
Manomulen. Connected wilh

MeasA t peisw had diffeunt
Woukua
tirsty insut tu puto tube n PpL.

Page 15 of 17
Carewell Pharma
In tvba, veloui of fuid incrtaud du to
Conatrict (narow) o, Hslts dexasu(thanga)
n pusu had (o) diffeunta
AH uasLd an
a
manomii and Man uis
vadu pu n tu fomula Cind Cokculat
rm
velou hiad on ra of ftow of uqu Hhid)
VactCJ2g 8H
ha
lP
Rota Mkr
IF a Voniablu aua nuler, l.t it

el
MLOmLs t EER ta of flow, so as to

w
produc a Coan head diferetial.

fou, rotamuters a knoum as aua uers.
re
Ainap
Ca
IF Consists of yetical,tapned and rawspouil

ubl in which plummut i plaud
Dulng t fuid How tvough ub,
t plummu rises and falls bl(ause Of
Vauahon an ftos

Page 16 of 17
Carewell Pharma
onstruction ROTA METER
Tt Consiss of veuhical tapexd

which mouned wilh
tubt,
a
narrow end doun.
ETapputd
of
rm
Tha u Vsvally mad
glass on which a linton Salu

ethud. or
-flot
ha tu
A solid plummet s plaud in plumnet
( diarun smallbu than narrouw

ub
lP
end ttvb)
Plummut/ ftoat may b made of fLOW
lod, aluminium, qlas and plastic
el
Woking
w
firsHy Rota mili tdtted n t ppa.

re
As f1ow upwad tmovgh a appud

fo of thuid Vouies
Ca
Th plummt, which Suroundd by th

fluid, riss and falls dpendng on th
ratof fiou
T geatinths fhow rat,tu ghn th

Page 17 of 17
Carewell Pharma
plummut ris in +th u.
a
T rotamuers, tu ptsu dop is camstaut o
rm
nuanly canya
Th fo May b read using th uppn edgs OF
Th eading
plumm
may bt
a
ha
an
tandmid for
indax (linna Cals)
HeCnding
lP
iktgrating. aud tonttolitng
el
Usud-ud in chumical Indysies, suth as bulk dwas.

w
Supply of a s Conbolled tvough rotamuker

re
t i sutala fo both Gas Liquids

Ca

Page 1 of 16
Carewell Pharma
Chapht- UNTT-Tst Date//
S1zE REDUCTION
Fmphe
a
rm
T tha procAs In which w Conveyt
ha
drug bulk_pmic nto Amall
pauhcles hrougkh AAny impac
lP
Obiechve
nud o Siz tduuhom?
el
incrtale usfa aALa.

ca
inEa ahserpron
Le enng 1 MUxing
w
Casan xing
p absaptim in u bady
re
Mechagm
Ca
Tmpaut
Atzitiom
uCombinatm of lmpout Attichien
Cuting
v CompesSIM

Page 2 of 16
Carewell Pharma
Puga
Date /
Tmpo Tn thiu d mslecules Lonventeo
AMall pouhicles hrough_anl
yp impac fmountof drug_cmoin_
Constant
a
nill
rm
HammY
I)£ttichion In thu Drug muhick callida

metmod,
ha
weth each cthr And educ tnue
Siz rom lan9 Malttudesto Analu
MLulu (pauhcu
lP
e fud enugy mill
el
mbind Impact ftichm n

pat
thu muthod,
2 Aihon
w
bakh apply imutanbusly.

re
ea Ball
(antain
Mill
Ca
uthing Tn u muthod,
wt Hduced lang
ug mletallsuo Amall hrough
Cuthig,
Augs
at MOAHy
d fo Bet f -fibiaya
eg Cuttey mll

Page 3 of 16
Carewell Pharma
Drug rmelpculls
v)omphessiom Ih tnu muthod
o
Hduc through Copim
by apblying pts3u On
a
rm
E
KaU
u MOkty
Ml
w-fo
ha
hand matudu
lP
La GUerring Size Reduchom
el
kidkls law
Rittinger'6 laud
w
11) Bond'3 lau

re
The mon w
Yeducotha pauthiclkA,
th enLAg- will be used to
Mok Amaller
Ca
-O0-DDOD
ODDoDDo DO 0000
Page 4 of 16
Carewell Pharma
kick's lau
Th enrg atquned tduck+nu
size of panicle propoiomallototh ratio
OF th initial size of a typical dimerxion
a
th final SIze of na dimensim
rm
whure=
ha
E Enuoy (/4)
diamutrof inithal pautiua siz
dg diamukr of-final paaiclkgize)
lP
K kick Conatan-
dula,= Roho sf chang Azi

el
)Rithingu's la
w
Th enngy equied fo sizze

Feduthom of urni matS iproportiomato
re
th n Surface area produced.

Ca
whut,
E Enugy cqutd T/)
K Ritfingu'h Consjant
d inihal
inal Aze

Page 5 of 16
Carewell Pharma
Page
Datc:
nand A lau
Size yeduchon ic
EnLAgyucedfa
a
propDvtiomol ath nLw Uuraks lengh
rm
l00 l00
W
Jda d
whul
E= thu enugy
N th ha
2quintd (T/rq)
Bond Wouk Tndx wonk tqued
lP
eduu a uui wtighE
4,= DiamMuhty fS1e apertune that allou
8O S of t
t Civemaapertuu jeed to pa.
Diamultr at- ma that auu
el
201 s pa
of th
Around
maltual
w
fatta Atfching an Size Reduchom

re
Haxdness
Mattial Spuhut
Ca
SofteningmperatuR
Stickine
Soapines
Cxplo sive
Mateaialyielding dusts that aa hamu
heath

Page 6 of 16
Carewell Pharma
Date
Hardne It u a urfau popeshy of thL

Maleaial
havder thu matoialth mok dithiul
Th
yeduc Sik
a
Matnalspwhut
rm
Substana'p Apuhu alto ofect
ha Size Hduchon process
eg Long panhcle duc throughcutting0
ha
Smalo haad pauhcles educ through iMpad
Settenig tenbeiatue
Substanu melt at m inceosing
lP
Soma
temb duaing AlZA reduChm ewaxy_çubfant
So, wt USL o
6vtBm fhu-
uk Cookugd oill eitur by a watr
el
jacket oy passig aspcam Q through

the uúpmut.
w
Sthickine maltial iM und to clsq th

A sticky
qunding Cquipmant and _Anould
re
-therefore ground 10 a plaun hat Can lo

Cleonid easil
Ca
Soapmneu hu i
fichon
mLaAutof t coefiicien-
Surfau thu
mattial Sf Cofficievt
6 pichonu l6w,
th Chushing may be mt dufficult.
Explocl Such
matuial must be Qrond wer o
in th prtAin o aninuE_atmosphutk

Page 7 of 16
Carewell Pharma
Date /
Hammer Mll+ uU wich udto kduca

panhcusiz hivgh poe
a
Cos peehim-
rm
Mopptr
ha Pcput wall
lP
Hammur
ellu shaft
el
Recieve
w
Principle
Conpu hon
WoAking
re
Us
Atvoutages
Ca
Disaduautagu
Pzinupu pinupl of Hmmur ul

baed on Thpac

Page 8 of 16
Carewell Pharma
Date
Wouing
tirsHy buly drug Maleual Ahou n Hepp

wuart o
a
un,thraugn
falin doum
rm
Stant MaL Wln and Hammu
wu Ataat iut hpauhiclesbdupohcA
And By uipac Žtaskd
ha
mduco
Ahd peduc hon, pauncles toud in
Leive ragh SCeen
Andtho pauhcle which_dos nat 2educ
lP
Ogan reltd in yvul. ead
el
Vsed to educ panhcles siz.

w
Advantaqs
UsLfulfo BLg paahles
re
Uuful-o haid.bugh pashidle

fasF n
Usudto duce in ve4
Ca
Anall paulèl
haqh Seen
Disadvauagui
Somd_podut (Naisy)
VeyHeat produto
Con us fbrau Mateaia

Page 9 of 16
Carewell Pharma
Date
Ba u Vud-b cdu gaiclk iz -nugn

iniplu Cowbinahm of Tpou Athinon
a
Conspuchm
rm
Matuia
Rall (stainlass Atal)
ha Sand
lP
ASodepnd) on Spud
el
lou X
w
TOOOOOO
O
ot X
re
edium
Ca
woPivg
Opun h Cap oFbox aud eaw.
h dug malecauusRuto
sfan mahinl, ano

Page 10 of 16
Carewell Pharma
Page
Date
adjuut t spud of nil w

Mdim Apud, A suE andL
educe pauidea
Aftenteduchom,Stop themAckin
a
thin
LxisE Aut YMaleial
rm
And sLpanate ou th ml m
Panhickl
F is used eduupaaicle sz
Adaurgy
houghinpau
ha
witout naise
attihon
lP
Neat_and CLRaM
Lypu opanides aduc easil
el
Dsadvautagu
Caxt 2tduces fibous Mateual
w
NoF 2ducu in yely big amom

pauhicdk
re
Ca

Page 11 of 16
Carewell Pharma
SUBSCRIBE us on YOUTUBE ate:
Huid Enngy Mul
Principle
Ttwouks onth pzinupk of fttitim
a
and Tmpau
rm
Conshuctiam
o
ha
Suen(cuivt)
PLp
lP
Hopp LeceivenL
fuhide
OOo'oo o
el
fir inle
w
Comuus
ak alosp a pip whih
has a diamter & -200 nm depending
Derau heught e th loap whuh
re
On th
ma b upto about MIL
n Happ fo inlel o paide
Ca
wmh we haue educ and

nte fo a
0utle
0 any
enut Qa fuid)
And frm Lalhu wt (2Cche)
ducedpouhdlA

Page 12 of 16
Carewell Pharma
SUBSCRIBE us on YOUTUBE Page
Date
Wonking
firsty
firstySolid paahiclu (Drug muhila whith w howto
Yeduced) inhnduced into pip hrough Hoppir
a
un clou t
rm
Thun, 1uboducod in Lp through
let 1withhgh ery
pkessu
Dueto hgh deqvee ofurbulenRIMpat
and odtitionforces ocCUK blw thu pauhicks
ha
and panhdesSukda be Amaller
Tun t il
pas hrough
Rceivtd in 2eiue agh
Aceen
lP
The ml i USRd to qrind heatSensuhvt
el
material tofin POwdur

Th mll i uRd grind thos drug in
which high cuq degree of Pt iSIeqLUEd
w
Ewil tduces t patide to to o micon.

re
Advantage
Ca
Th
Th mil usedto qrio h makrial to
pouw der
i
Th pubila Siz fpduder Can be (Omballed dul
classifier
Contaminahion
Thwe fth product
isuseful torgrinding hea sensuhe substanro
Suth a Sulphananidas vitamina and atibiotic

Page 13 of 16
Carewell Pharma
Page
Date
/
DisadvanlagA
a
Hgh enLAgy CoNSumphon
AmonphouS Comtev du to high
rm
Genrahom Of
energy mpauE
ha
Fdg unnur Mil
Pinupua
wOekron h pinipla OF
lP
CYushing Lcomprtssiom)
Conshuwtiom
el
w
Matua
Iaiu
re
(onAuE f a Jwo heavy ghE

ralpr whih reled withtu uu
Ca
Bhaft
ro-Ulur MON bad uhidh iu
Madu sf AtmL 0 grAMilr
And heu Ralurno hadoned wth
boA wuth qieA Buppoao it

Page 14 of 16
Carewell Pharma
SUBSCRIBE us on YOUTUBE Page
Date:
laaking
Pauhidea (maltial pu on t bad, bl ralur

o
a
Coilh h lp Acrappu
Tn, t ollc Aautd Jo b rallud
rm
and aluo bad Fevolw at Sam im
Bad thAn
wth qrtaten speed or
rollr So panhitleswl b Ahaned
ha
Cuhud h rouglh rallr
Thun Pawdu UCaUodcd ud Lpanaked
hraugh
lP
Thumill u_uud to qrindtough
maltrial to ve in pauhicdes
el
Thu mill uSLd on plant batud producta

Advawrage
w
He don't nud to givt attnhon duing

re
Disodvautaqu
Contaminahon of othuL malCualu
Ca
Nat usLfon Aticky maleua

MOAL Apa nan
(onsunuhg
btuL mll_
Enuo coumphm
high

Page 15 of 16
Carewell Pharma
Page
Dute
End Runn
ull
a
Principlu
rm
wok6 tw piniplu of impac
Consteuction Pestle
Stationay4
Stos
ha
lP
END
RUNNER
MILL
el
w
moto
Gn raahing pesti
fndth aML alo SaLAtmt prnt
re
insid h Motor
LWorkia
Ca
isHypu dug pauhdles un Atahiomay

MOtor which
Atau m ul
ha o educdd
Jhin AndPestl
fallin doun Aahonay moto
And t Ctat inpauE m dugs which
pHCont in motoy

Page 16 of 16
Carewell Pharma
Page
Date /
Thun
Amltdto rotat.on rotahng
aukd Crushing (Lattihon)
thiovgh impaut and_atbibiom panlscles
a
Aauttd be Bmallu
Att
rm
fduction Colleck h pin powd
Ucudo cduc_ dngs matuial ntd
ha
veLy in pachicleLpouwdu)
AHdvautagu
lP
tasyto handle.
No mart hRaF_produt
Le eltciciti
el
Disadvawtoqus
Not uLLd-fe Stidty mattaia
w
Not utdo blg paahiclRa.

re
Ca

Page 1 of 17
Carewell Pharma
Car
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Carewell Pharma
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Carewell Pharma
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Carewell Pharma
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Carewell Pharma
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Carewell Pharma
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Car
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Car T
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Carewell Pharma
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Page 16 of 17
Carewell Pharma
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Page 17 of 17
Carewell Pharma
Car
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har
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U-1, Pe-1, Carewell Pharma

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Page 1 of 17

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