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  • L-4, U-2, Pharmacology 1

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    Najid Iqbal Khattak
    36 views4 pages
    This document discusses the regulation of receptors in the body. It explains that receptors can be up-regulated or down-regulated through various mechanisms. Up-regulation involves increasing the number of receptors on cell surfaces and sensitivity to hormones. Down-regulation decreases receptor numbers and sensitivity. The document also discusses how drugs can interact with receptors as agonists, partial agonists, inverse agonists, or antagonists.

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    Pharmacology

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    This document discusses the regulation of receptors in the body. It explains that receptors can be up-regulated or down-regulated through various mechanisms. Up-regulation involves increasing the number of receptors on cell surfaces and sensitivity to hormones. Down-regulation decreases receptor numbers and sensitivity. The document also discusses how drugs can interact with receptors as agonists, partial agonists, inverse agonists, or antagonists.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    36 views4 pages

    L-4, U-2, Pharmacology 1

    Uploaded by

    Najid Iqbal Khattak
    This document discusses the regulation of receptors in the body. It explains that receptors can be up-regulated or down-regulated through various mechanisms. Up-regulation involves increasing the number of receptors on cell surfaces and sensitivity to hormones. Down-regulation decreases receptor numbers and sensitivity. The document also discusses how drugs can interact with receptors as agonists, partial agonists, inverse agonists, or antagonists.

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    © All Rights Reserved
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    of 4

    Page 1 of 4

    Carewell Pharma - A family of learning


    search CAREWELL PHARMA on Youtube, Watch Free Video lectures
    REGULATION of RECECDRS
    Maintain th homLostatic of ceptors.

    Up-Requlation

    Down- Requlation
    m a
    HActivoahon
    Deachivohion
    Desuchion

    1) Up Requlation
    a rMOnusactuuin

    Of
    thet
    eceptors.
    ak

    ypersuniti)
    P h
    increaCemant in sunihuty

    l l
    HanmonLS
    in
    e of
    Conc
    hanmOn

    UU e w
    a r (Noumal
    RECE PTORS

    Cndihon)
    RFCEPTDRS

    (hamouuS deceakes )

    C fctivaien ofinachve
    Hceptors
    sensithul of
    upRaqulatin

    inuea
    HCepior

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    visit website to download free pdf notes
    Page 2 of 4
    Carewell Pharma - A family of learning
    search CAREWELL PHARMA on Youtube, Watch Free Video lectures

    incta in number Of Eceptor On u


    Surfacu of agu cells.
    nccaLS of celwan compont
    -Dul td prolongcd uce of Outagonist
    m a
    Dwg
    a r
    efe

    Down Reqvlahion >

    P h
    Hne aR

    l l
    deceasmbnt in sencitiuy

    e
    HLeptos.
    HaumonLs

    O
    e w
    r
    O doO00
    O Oo

    Ca
    U
    RECEPTORS
    RECEPTORS

    (iras () in tnc" of
    (Nonmal ondihon)
    honmonl

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    visit website to download free pdf notes
    Page 3 of 4
    Carewell Pharma - A family of learning
    search CAREWELL PHARMA on Youtube, Watch Free Video lectures
    machvaion oF recepiort
    decreansa in tanumbu of reuptor
    DouJn
    Regulation
    on u surfau of -tangut cell
    les senskive
    a
    making cells
    Ho a hanmont (onorthin a9u).

    m
    decrea produchion of kceptors.
    r
    -Dul to prolonged u
    Dryefeurh
    a of 0gentshs

    ORUG RECE CTOR


    l P
    INTERACTIO NS

    Tha drvg
    e l
    bind with HCaptor" 4d

    w
    is Rnou as dug- receptor interactiom

    r e Respons

    Ca Z
    Veepto (D-R

    Dw OF diffewnr typu on u
    basis ot en achon -

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    Page 4 of 4
    Carewell Pharma - A family of learning
    search CAREWELL PHARMA on Youtube, Watch Free Video lectures

    m a
    fAgonists|+| RECEPTORS full
    a r Respon su

    -|Partial
    agonis
    Receptors
    P h
    le KeApona

    nverst Recaptors
    l l Opposile (differnt)
    a9onits
    e Respons
    Antagonis+Recupor
    e w NO HAponsu (effec)

    a r
    C
    www.carewellpharma.in (free notes)
    visit website to download free pdf notes

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