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Polymer = 1

Monomer =
Pharmaceutical polymers) Polymerization =

Homopolymer =
Copolymer =
Degree of polymerization monomer repeating unit
polymer chain) monomer 0
0
Degree of substitution functional group
functional group
monomer
0

0

classification of polymer) classification of polymer)

Thermoplastics = Water soluble polymer Hydrophilic polymer


amines, imines, ether,
Elastomers = alcohol, sulphates, carboxylic
Thermosets = Hydrophobic polymer functional group
classification of polymer) Polymerization

Natural product acacia, chitin, chitosan, gelatin, pectin, rubber, Addition =


sodium alginate, tragacanth atom
Synthetic polymer cellulose (MC, HPMC, HEC, CMC), dextran. molecule
Eudragit, PE, PEG, PVA, PVC, PVP, silicone, methyl methacrylate Alkenes

Polymerization
Pharmaceutical excipient
Condensation = Drug delivery PLGA microparticle


Hydrogels
functional
groups Adhesive biomaterials
Pharmaceutical excipient Acacia
Coat tablets: Microcrystalline cellulose (MCC), sodium carboxymethylcellulose Emulsifying agent stabilizing agent suspending agent tablet binder
(NaCMC), hydroxypropyl methylcellulose (HPMC), hydroxyethylcellulose (HEC), viscosity-increasing agent
hydroxypropylcellulose (HPC), PEG, povidone ออ
เออ
Binder: Acacia, gelatin, sodium alginate
Plasticizer: PEG
Thickening agents: Xanthan gum

Acacia Chitin and Chitosan


Coating agent disintegrant film-forming agent mucoadhesive (
suspending agent emulsifier tablet binder viscosity-increasing agent
tragacanth
binder pastilles lozenges) acacia deacetylation

bioadhesive)

ะ ✓ เ ④
Chitin and Chitosan Carboxymethyl cellulose (CMC)
Coating agent stabilizing agent suspending agent tablet and capsule
disintegrant tablet binder viscosity-increasing agent water-absorbing agent (
mucoadhesive)
gene Na+ Ca2+
alginate >>>
, alc, ether, chloroform

Carboxymethyl cellulose (CMC) Ethyl cellulose (EC)


Coating agent flavoring fixative ( tablet binder tablet filler (
viscosity-increasing agent
Ethyl cellulose (EC) Polymethacrylates
Film former tablet binder tablet diluents drug release modifier (
hydrophobic)
*** SR

organic solvent)

thickening agent) emulsion

Polymethacrylates

Eudragit RS Eudragit RL
sustained release
Eudragit NE30D Eudragit NE40D
diluents
pH Eudragit S, Eudragit L, Eudragit E Eudragit FS
enteric coat
Cellulose Acetate Phthalate (CAP) Cellulose Acetate Phthalate (CAP)
coating agent
*** enteric binder CAP

CAP EC

Hydroxyethyl cellulose (HEC) Hydroxyethyl cellulose (HEC)


Coating agent suspending agent tablet binder thickening agent viscosity-
increasing agent
HEC
Hydroxypropyl Methylcellulose (HPMC, Hypromellose) Hydroxypropyl Methylcellulose (HPMC, Hypromellose)

(
Coating agent film-former rate-controlling polymer for sustained release

viscosity-increasing agent
stabilizing agent suspending agent tablet binder HPMC
2-5% 10-80%
i
thickening agent
methylcellulose HPMC
HPMC w/w
ointment

Methylcellulose (MC) Methylcellulose (MC)


Coating agent emulsifying agent suspending agent tablet and capsule
disintegrant ( tablet binder viscosity-increasing
agent binder
, alc, ether, chloroform MC
Pectin Pectin
Adsorbent ( emulsifying agent gelling agent thickening agent
stabilizing agent bulk forming agent)

emulsion
gel beads)
Pectin
Amidated pectin (Pectin
Pectin calcium Pectin methoxy

Polyethylene glycol (PEG) Polyethylene glycol (PEG)


Ointment base; plasticizer solvent suppository base tablet and capsule
lubricant
ointment base ointment
PEG PEG

emulsifying agent
binder
Polyvinyl alcohol (PVA) Polyvinyl alcohol (PVA)
Coating agent lubricant stabilizing agent viscosity-increasing agent

emulsion

PVA glutaraldehyde microsphere

Polyvinylpyrrolidone (PVP) Polyvinylpyrrolidone (PVP)


Disintegrant dissolution aid ( suspending agent tablet binder
N-vinyl pyrrolidone (monomer) binder
wetting agent)
PVP K (K value)
Tragacanth Tragacanth
Suspending agent viscosity-increasing agent

Hydroxypropyl methylcellulose phthalate (Hypromellose phthalate, or HPMCP)


Coating agent ;drug release modifier (

*** enteric
Polyacrylic acid (carbomer; carbopol) Croscarmellose sodium
: disintegrant

Alginate Xanthan gum


Gelling agent viscosity-increasing agent : viscosity-increasing agent
Gaviscon anionic polysaccharide mannose glucose glucuronic acid
carboxylate Carboxyl pH

0
Veegum Drug delivery
: viscosity-increasing agent PLGA microparticle
clay
magnesium aluminum silicate bentonite
aging
ing
00

HEC, HPMC, PVA


Sustained release - EC, Eudragit RS RL
- HPMC
Enteric coated CAP, Eudragit SLEFS QUIZ
plaster CMC, Pectin
CMC, MC
, alc, ether, chloroform

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