Professional Documents
Culture Documents
The concept of dividing humans into categories has been with us for a very
long time. Greek philosopher Aristotle attempted to classify living things in a
hierarchy. According to his thinking, some humans were born to be kings,
whereas others were determined to be slaves. In the 1700s, Man was divided
into a handful of races: Africans, Asians, Native Americans, and Caucasians
(Pacific Islanders were thought of as a fifth race by some). It wasn’t just a
horizontal classification, but a vertical one too. Thinking of Africans as
biologically inferior to Caucasians certainly facilitated their treatment during
the slave trade.
To what races do these women belong? It turns out they are all from the
African continent. From left to right, we have a Namibian, an Egyptian, a
Malian, and a Kenyan. If “African” is one race, why do all these women look so
different?
But skin colour, hair colour, eye colour, and other physical traits are all under
the control of genes, so doesn’t our DNA have something to do with race?
Our eyes tell us lies that DNA can pulverize - The DNA in our cells is
littered with variants, little changes from one individual to the next that are
responsible for many of our physical attributes and our predispositions to
disease. It’s like we all have the same book, except that my edition has a few
typos and local spelling differences that yours doesn’t and vice versa (e.g.
“color” versus “colour”). When we add up all of these variants, that is what we
mean by “genetic variability”, the number of DNA differences from one person
to another.
So do you think there is more genetic variability between these two penguins…
or between Taylor Swift and Kanye West?
In fact any two unrelated human beings on the planet are 99.9% identical in
their DNA sequence. Only 0.1% varies, and here’s the most important
takeaway message from all this. It also happens to be the most replicated
finding in the scientific literature on human variation.
If you didn’t know that, don’t worry: you’re in good company. Three out of
four college students taking an introductory course in biology and genetics
also do not know this.
And since skull sizes are being discussed again in certain corners of the
Internet, 90% of the variability in their volume also occurs within (and not
between) human groups.
This is a big snag in the argument that race is a biological reality. This finding
—that there’s more diversity within than between groups—is true for most
physical traits, with one prominent exception: skin colour. Why? Because skin
colour is under tremendous selective pressure. It varies depending on how far
from the equator we are, because a darker skin offers better protection against
sunburn, skin cancer and related damages. People with naturally darker skin
were better adapted to their environment and were more likely to reproduce.
The fact that a Maasai and an Aboriginal Australian both have very dark skin
is not because they are part of the same biological race, but rather because
both have lived under a very harsh sun for generations. So skin colour is not
evidence of race being a biological reality.
But what about sickle cell anemia, I hear you ask. Isn’t that a disease that only
affects Black people?
Race and medicine - The truth about sickle cell anemia is more complicated
than that. The sickle cell trait is a variant in our DNA that offers protection
against malaria. Over many generations, people who were exposed to malaria
were more likely to reproduce if they had this trait, so this trait was selected
for. When you have two copies of it, however, you can develop sickle cell
anemia. So do only Black people carry the trait? No. While it is commonly seen
in people of sub-Saharan African ancestry, it can also be found in
Mediterraneans, Middle Easterners, and Indians. It is not restricted to one
race but rather to many populations that were all exposed to malaria.
But there is another example where race seems to play a role in medicine: the
drug BiDil, the first race-based prescription drug in the US which aims to treat
heart failure. It was said to be a breakthrough for African Americans, but
here’s the twist: the clinical trial that led to its approval only tested African
Americans. How can you pretend your drug can only treat one race when you
haven’t tested it in another?
Racial health disparities within countries are often due to the physical tax of
discrimination, poverty, an increased risk of living near hazardous waste
facilities, lack of access to healthcare, and differences in behaviour. And this is
important: race is not imaginary simply because it’s not biological. Our
perception of it has real consequences on the health of others because of how
differently we treat them. As a study from the early 1990s demonstrates,
infant mortality is twice as high in African Americans than in their white
counterparts… unless you look at members of these groups who are enrolled in
the military and receive care at the same army medical centre. For them,infant
mortality rates are more or less the same.
Some doctors still use race as a useful proxy, but this assumption carries with
it the risk of withholding effective treatment for some and of using ineffective
treatment in others. Socioeconomic factors, culture, behaviour, and where a
patient’s ancestors came from are more informative. As Francis Collins, the
director of the consortium behind the Human Genome Project, once said,
“race is a flawed surrogate.”
Race is relative - So what would you say is Liam Neeson’s race? You
probably said “white”, but a hundred years ago, the answer would have been
“Irish”. In the eyes of North Americans back then, the Irish were a separate
race. Racial categories change over time.
Pakistanis and Indians are thought of as belonging to the Asian race (an idea
perhaps more common in Britain than in North America), but at the level of
their DNA, they are more similar to Europeans than they are to East Asians.
Racial categories are not reflective of the underlying biological reality.
Race is a real concept that we use as social beings. As for whether race can be
found in our genes, the answer is no. Biological ancestry, however (which is
distinct from race), is real. Where our forebears came from can be seen in our
DNA (to a certain degree), but ancestry does not map onto race, not even
close. We may intuitively think of Europeans, Africans, and East Asians as
three circles that barely overlap, like the Olympic rings. Time and time again,
however, genetic studies reveal the opposite. They are rings all right, but they
almost completely overlap.
We are a lot more similar than we think, and the ways in which we differ have
little to do with our ideas of race.
Take-home message:
- There is more variation within a race than between races at the level of our
DNA.
- How we define races has varied throughout history and differs from one
culture to another
- Studying our DNA reveals that races are not real in a biological sense, but
how we treat other races does have an impact on their health because of
poverty, stress, and lack of access to healthcare.