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LEARNING ACTIVITY # 14
Cells require chemical energy for three general types of tasks: to drive metabolic reactions that would not occur
automatically; to transport needed substances across membranes; and to do mechanical work, such as moving muscles. It
obeys the law of thermodynamics that a system cannot work unless there is the input of effort or energy. In living systems,
energy take on the form of ATP molecules.
It is emphasized that ATP is able to power cellular processes by transferring a phosphate group to another molecule (a
process called phosphorylation). This transfer is carried out by special enzymes (ATP Hydrolase and ATPase) that
couple the release of energy from ATP to cellular activities that require energy. In other resources, this process is termed
as coupled reaction. Coupled reaction is a chemical reaction in which energy is moved from one side of the reaction to
the other with a typical intermediate. Cells use ATP to perform work by coupling the exergonic reaction of ATP
hydrolysis with endergonic reactions. ATP donates its phosphate group to another molecule via a process known as
phosphorylation.
Although cells continuously break down ATP to obtain energy, ATP also is constantly being synthesized from ADP and
phosphate through the processes of cellular respiration. Most of the ATP in cells is produced by the enzyme ATP
synthase, which converts ADP and phosphate to ATP. ATP synthase is located in the membrane of cellular structures
called mitochondria; in plant cells, the enzyme also is found in chloroplasts as it carries out ATP synthesis in the grana
thru photophosphorylation.