University of St.

La Salle
College of Nursing

DRUG STUDY

Name of Student: _Artillo, Aljean Altheo L._________________________________ Section and Group: __BSN3-B_______
Name of CI: ____Ms. Marisse Arroyo_RN. MN.________________________________________________________ Area of Exposure: Oncology Ward

Nursing
Name of Drug Dosage/Frequency/Timing/Route Mechanism of Action Indication Contraindication Adverse Effect
Responsibilities

Generic Name: Dosage: Prodrug with -Give oral drug -Hypersensitivity CNS: Headache, tremor, -Lab tests:
mycophenolate -1500 mg po BID immunosuppressant on an empty to mycophenolate insomnia, dizziness, weakness. Monitor CBC weekly
mofetil properties; inhibits T- and B- stomach mofetil CV: Hypertension. Endocrine: for first month,
lymphocyte proliferation Hyperglycemia, biweekly for second
Prophylaxis for Kidney Transplant responses inhibits antibody -Adjust dosage -vaccination hypercholesterolemia, and third months,
Rejection formation, and blocks the with severe hypophosphatemia, hypokalemia, then once per
generation of cytotoxic T-cells. chronic kidney -varicella hyperkalemia, peripheral edema. month for first year.
Adult: PO/IV Start within 24 h of failure. GI: Diarrhea, constipation, If neutropenia
Brand Name: transplant, 1 g (mofetil) or 720 mg Prophylaxis of organ rejection -pregnancy nausea, anorexia, vomiting, develops (ANC <1.3
CellCept (sodium) b.i.d. in combination with in patients receiving allogenic -Do not open or (category C) abdominal pain, dyspepsia x 103/mcL),
corticosteroids and cyclosporine kidney transplants or heart crush capsules; Urogenital: UTI, hematuria, withhold dose and
transplants. avoid contact -lactation renal tubular necrosis, burning, notify physician.
with powder in frequency, vaginal burning or Periodically monitor
Child: PO 600 mg/m2 (mofetil) or 400 capsules, and -children 5years itching, vaginal bleeding, kidney and report
Classification: mg/m2 (sodium) b.i.d. (max: 2 g/d wash thoroughly and below stones. abnormalities for
Immunosuppressant mofetil, 720 mg/d sodium) with soap and Hematologic: Leukopenia, any of the
water if contact anemia, thrombocytopenia, following: Kidney
occurs. hypochromic anemia, and liver function,
leukocytosis. Respiratory: serum electrolytes,
Respiratory infection, dyspnea, lipase, and
increased cough, pharyngitis. amylase; blood
Skin: Rash. glucose; routine
Body as a Whole: Leg or hand urinalysis.
cramps, bone pain, myalgias,
sepsis (bacterial, fungal, viral). -Monitor for and
report any S&S of
sepsis or infection.

-Comply exactly
with dosing
regimen and
scheduled
laboratory tests.

-Report to physician
immediately S&S of
infection, such as
UTI or respiratory
infection.

-Report all troubling

adverse reactions
(e.g., blood in urine
and swelling in
arms and legs) to
physician as soon
as possible.

-Avoid taking OTC

 antacids
simultaneously with
mycophenolate
mofetil. Separate
the two drugs by
2h.

-Do not breast feed

while taking this
drug.

Check patient’s
identification and
diagnosis

Check the
medication order

Generic Name: Dosage: Misoprostol is a synthetic Misoprostol is -Pregnancy when -shivering/chills

Misoprostol 400 mg tab prostaglandin E1 analog that indicated as a used to reduce
-diarrhea, abdominal pain
stimulates prostaglandin E1 tablet to reduce risk of NSAID- Observe the 15
1 tablet
receptors on parietal cells in the risk of NSAID induced ulcers. -hyperthermia, nausea, vomiting rights of drug

PO the stomach to reduce gastric administration.

Brand Name: induced gastric -Hypersensitivity -flatulence, constipation
acid secretion. Mucus and
Cytotec ulcers but not to misoprostol,
BID
bicarbonate secretion are also -dyspepsia, headache
duodenal ulcers prostaglandins, or
10:00 am, 2:00 pm increased along with Educate patient
in high risk prostaglandin breakthrough bleeding, and
thickening of the mucosal about the side
Classification: patients. analogues menstrual irregularity.
bilayer so the mucosa can effects of the drug
Prostaglandin Misoprostol is
generate new cells.
also formulated
 in combination Before giving the
with diclofenac to medication, ask the
Misoprostol binds to smooth
treat symptoms patient if he is
muscle cells in the uterine
of osteoarthritis allergic or
lining to increase the strength
hypersensitivity to
or rheumatoid
and frequency of contractions prostaglandin.
arthritis in
as well as degrade collagen
patients with a
and reduce cervical tone.3
high risk of
Ask the patient
developing
what other
gastric ulcers.
prescription and
Misoprostol is nonprescription
used off label for medications,
the management vitamins, nutritional
of miscarriages, supplements, and
prevention of herbal products he
post partum is taking or plan to

hemorrhage, and take.

is also used
alone or in
patient to avoid
combination with
alcohol and foods
mifepristone in
that may cause an
other countries
increase in GI
for first trimester
irritation.
abortions.

Instruct the patient

to report
bothersome side
effects, including
severe or prolonged
headache,, or GI
problems (nausea,
diarrhea, vomiting,
constipation,
heartburn,
flatulence,
abdominal pain).

Advise the patient

to comply exactly
with dosing
regimen and
scheduled
laboratory tests.