|Pag

Dat

Ami
CH

CH-NHL CH NH-CH H,C N- CM

3amu
Hehut am
Nomoncahue alh anamna
CHCH2
NH ehanamuu
2 CMCMCHL NML VohanamuAs
3 CH CH CH
-ohaMomin
oha
(H 4- CHL-(H
N Milhyl 4nanamia
s CM- CM3
NN- dumulhyl centAg Mmuh angs
CH

CM- N- CH, CHHCH2

NN-diehyl
Jut anamins

1NHCM>-CH= (, - on-2- en-1- amt

NHL-C11) NH Hexan -diami

Amiab n4cna MuA

NM
munylanuline
O
NH
-romoani line

NN-di muHplengenami

Pehuahon
Ho]/mana Anmmonolusia)
fHom alkyl halidn
HT amuae
(H NH
CM + N2 -
CH-N4-(H3 + HT (2aminu
CHNH CH
CM N-CH t HT
CH (3 amuAg)
SCH- N-CIH,
 |Tagr No.
Date

CMNCH CH T CHs), n*Pr

CM3
(uaJi
quaknu)
*Dnadvantag w gut_a MixtMe_dmin
nahtad a9hh úny .

Limitaho

Ammonolysia tu duAadvantaga
yudding a miXhue huim ay Aecond aly
euh y amias and alo ppakunay
amm oni uh Aall.
Can be hieented by uw NH in eX( 0ny
hAIMyAmine Oumad
V

y.imp

Cubaid halamida Sunnoaig

N-
ac. KoM
- 112D

D.
halam

Pthalanida -KRx
(DoM_
Ng on
oor
amie
PPhadi
 Limi-ahonn

Wped ohe NauingTamiu only aun

AAomhc anine (nAot e haehued y tha
muho.d y
do not undugo Aucleohhilic Auaht han.
HayA hoidu
wth Hu anion doumad hal.omide

3Reduch'on nita0 oM hound

-NO Sno fe >

HUU NHL
iAH
Ay-NO day e
As - NH

Konuy Ni a

+ehano

Reduch on oAaid
Na- Hs OH &NHL
TATHu o4 a7C

Aedkecduch'on s AitAile and jaontHilea

-(NtHLiAlMu 6KOR
Na-Ca MgoDH amine)
NitAile
 Pay Ne

Date

CHs-NC + H iAH 01.

CHNH CH
iADaitAile NG-HoH
amina)

6Homan buomodi du Dtgao dahion

No0M 6H R- NH1
amid KOH +K-BAo Noha
H20

Phyaicol oluuhiea
1Bokng foint
T boiling. hoint
aminu au lcnea omhaned to
Hhode dtohola ad adds ecawe -bH bond
in moe
nolau comhaued NH bond
imaiy_aminM Seonday amin Teahay amu
Qudoi
BP)
n mo leculau H-boncag ja m04e n Lami
Com au ed o amin thuo e wo H-ah
avcilable H-bon domak'on in it, whueaoi
mins do not haw intmoleuda H-bondig
duus s ob senu sH_ahbu.
Solubili y
auhhah_amnA MAoluble in hale as hiy (n
lowe
OAM Rbond with walu moleculen_houvtnea Aolul lihy
amin
deuean0 Loih inuease in mola ma
inucae in AiL ahy duothobic
alkyl haul
dus
anlins
Ehy amiA 1A t Aplublei o wae whuea

altoholom -boncy i h waku molccules

A yl e n ab aniliae
I a han Aolluble in ak
inqueased A4L kyduojh olbi alkyl h4t
du
eMeno) hue 1 hluence io -3onding
uti hunte, Onilins inot Adluble
hindu anco) ond
in oat
CH ( -NH ehy amins

R- N--

R-N- H- O-H

H-bondinG.
-N
 Paye No

Chonica Reach'on Ami

1)baic hauace
becae ueence lonu hau o eletzon on
NitAOGNaom esE= _ and 3 anineA aAe bai
caiin innahu
Ke -og Ke
N

lauQu h valu h Amalleu h value e

At Aon guthu bax.

.AEhhahic aminA m basic omhaued to vHs

AAhahe omiae lon ainelectaon- uleming_ahy
gHou hhithinueanen dectaon dunaity a No
Aaaulk
Comhoed o Gmmonia
it donaks ita decka00
hain mote eadil

Non-Aqdeou GMeous Phaue A9ueow hau

TVhane
Aaid ky
dehunds o dehonda Dn
) nduthvt e c ) nduch e eteck
Slaicado
3) Hydahan elet
 Date

AANaNg 23 amia anmoni a in inUOing-

0tdu baAidy LGaneow hhao)

NH< 142' ? <

(HNHRNH wMRN
3 amine 3alhy gouai dedzon danaiy
10 moeo n N dvm]

Aqueo f'hase

nduhv eeck 3 amin7 2 amia 1omins N Hz

Stui actoa
amine 7 amns 7 3 amins >NHz
induch e)
Gaeae ha aoudin4 alb quulh eala
hinduana hyduojsn Jbondinq hu basiity
My dah an Ee
V
H0H
H . OH R-N HOH R-N

0
amM ONUN 3 unmoruum
ommo um Cahan
Cohan
 Page No
Date

ami amin 3 amin 7NHs

eake th atabhlhy hudtakd anmoniun Cahon

m o e in th daogh koadingea
Aanidhy
fincd udau of boiu I0 amiL 10 aqueouA_ hhax

aminu7| amins> 3 aminu NH (KE CH

Aykafion
ANHRx one RaNH +HX

RaNH Rx RNHX
Ryn®x

3) gl.ation Rtadi on with Qid chlaids aid

anhyduides
+R-NH -N-H-R H

R+C- Rn - -N R HU
 d-0--CKs+ CMs-NH CH3-NH-CaH
+(H3oOM

Bnhoylalhon
NM NH-C-CH
+ CH-CU idine
HC
Anilino) Aabanido)
NH N-GHKs
C Hs-C-U
NaoM
Benganili de )

5hi hone amah'on

Cchihae

RNH + ends+o R-NC3 K +3H0

(ale-)
albyl 00y nds
alEyl ausylanine

oomah iaay aminu whon

Koth olikhaic and
dhlo4Dom andalcoholic Aoluion
WMned i h which has
iaocyanitlea 1 Cauuytomine
KOM Aedua
ne ant odbu hio e t in_ued
1aminl om nd3 amin
iphaguah
 Puyr No
Date

Keadion with nitADadd

KNM) HNO NaNO, +H R- N»'u

-oH+ N Hu
NM
H N O NaNO +Hu Nu 2HL0
213-218 K

)Reachan with Jyengans Aauhhon chloaiolk

OA CHs So» UoMinabeg Aeagent

Tept
A
amia)
huren
O -NH-CaH E
n d 5 a m i "

Aoluble in
aN2ali)
HA

HNCaHs -CHs
O

amiaa) Gmoluble in
alhai)

tHU
aumino d» no Aeat wih Rim beugAagat

Piodutk om aminy la oluble in a ali eca

ACentu o AoduuLom _aming in
IAMolubhle in akali Rcauge abaena H
Eleckaoqki lic Aubahtuhon ueathon NH2 qLou
1 uihohaa diaeching

Hominahon
NM. 4 HhM

ub-aLbAomo@nins
wehilet
ee
Achvahag NH uoucan be by
cot4olled
okthg h N qao gkouh by auhlahon i h
Qchcankydid.
NHL NHCOCH

+CH

CMyCoon 6H

NH NH NHCOCH

N hm in ostamick ackilia
Lon ain o_elecioM on
AeJonana s a
Wtat ith oxuQen atom due
t bengu
tin h nvalable to donation
deueae)
Sing hw achvahng eplec
aAlien Aeonan uwa wih
N C(H
entn and hnce athvahy
PMec
 Page o
Date

NitAas on NOL

NH NH NH

HODs, HSo
248h
NO,
(a7) NOL

471)
517)
atnongly aidic madiun, anine iahoionaked h
JOAm dnEilinium 1on which io mka 'duechag eou
huetoreAubatanh al aount ometa haoducha i
NM NMOCH NM

d,
yicins HLO NO moy

HaOH*

NH

NO

Suhongion
NH NHs HSou
3. NH
Ha&O
4S3-413 K
SOLM

Aide (ata Heacfon

CMNH AIds Co He H AIuS

Anlin da no undauga Fidl Caaa eachom (ahyla

Gylahon) duu hal doumahonJl bae ani
Ond lewIA au aumundum chloida (AIUL). Du
nia nitADgen ani lMA úcqiAeA
tw chaup nd
Qcto O a
otnong deach vahng gaou
 Fage
Date

piagonuyum Salk

Dia Aoum salk RNx6

N diagonium gMoun
HLy Aomahe diagonium Aat au uch mote
slallecomhaued o dithakie diazoniun adk
becawae o diahauaal iive chage_ovA
thu lentn Aig-

NEN =N=X

= N=N
N=NNO
N N e

Yxehaxahion
N
K
NaNO M0 213-3

in
MA AocwM ConvtALan oimay Momai amins
TA diagoniumAalk is Calle diagoinahon
Du o ia inutabili, diagoniwn AaiA 9enual
no aoed and ed onmediaklapeyit
uenauahion
 Tagr No

Chenmical Keathon
Reachon invcluinq dishlacanmunt AitAogan
oochans involviag Aeknion dialo iouh
Cu/H Aud 4N
CuBa/
SandAny
A Bx + N2 Aeadkn
CuCN KCN Au C+ N
Gu/HO AuU+Nz ux o
Aeadhr

A-NF HBf Ax NX HBA AA ba + NL+uX

NG NO2 a
K A 4 KU + N
HH-N0L + N +NAbF
HBFu AHN'8fy Af
BF +N
HsPOHi Ax -H

+ N 4 H,PO3
HO
CHCH0 A-R + N + CH3CHO
+H
MO AA0 N + HUL
 Reacrion involving nHon odiakouOun
NaU
N= NT
OH
K dH

hyduxy 940en
sona
(ang dye)
NU
0
H N M

-N= N-

-amnoaho bengan
Cyutew dy
+Ho

Amignmen
V
Wie thu ollowing Atachona i

Homan BuomQnids neachion

Cdubyiamis Heachan
Gabstel-halamid e Ayatoaia
Heachon
Couhling
Diatnqiah behoeen hu ollowing haua Teat)
Lenaylamins
Aniliu and and aNilin
Ehyl anine
 P4e No

Methyl amil and dunuthyl amind

Acount onte tha folloaing

Anilias doe no ndugo Faiedal Ca eation
Gqalbniel- Pthalamids Aythoai in hueee
Ae haing amins
Artilhae on NtAahon gives Aulrhanthal amout
mta-nataD aniln
AMAGnGa hu olowin
10uting Hdu GH OM (CHs) NH GH
banic stAength
Deueaing udus in 4aneou ihau
CHH NH, R ((aHs), K CHJs N
Deue0ing d ohaaiatAengh in aqueDun Nhon 1
NH
NERT
1b96ie tu stAuthur AB and in the
4pllotwing ARGth on

(H, LoDM NH A NaOB4 bNGNO

(M NO, fe/Hu AHNO +Hu

15
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Date

C
H