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or

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ma

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rom f
usi
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e

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ketoint
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oductI
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on
onkidneycor
tex.

•
Sir
,lSepi
sav
ail
abl
ein200mgaswel
las400mg.

.
Asweareawarethatevenifami
noglycosideshav
eexcel
l
entgr
am negat
ivecov
eragebutt
he
pr
obl
em i
snephrot
oxici
tyandcot
otoxi
city
.

Sosi
r,webr
ingi
sepamy
cinduet
oit
smol
ecul
arst
ruct
urehast
hel
eastnephr
otoxi
cit
y.

Andsi
r,t
akingintoaccountt
hesafet
yandef
fi
cacyoft
hisi
sepami
cinwehav
edoneanI
ndi
an
st
udyacrossthreemajorhospi
tal
s.

Thati
spear
leshospi
tal
,kol
kat
a.Maxsuperspeci
ali
tyhospi
tal
,del
hiandnanav
ati
hospi
tal
,
bombay.

Thekeyfindi
ngsofthisstudyar easfol
lowsandi sment i
onedinthi
sbookl et.
Soisepamicinwas
foundtohavemaximum suscept i
bil
i
tyagai
nstEcol ithatis93%.Andisepami ci
ninthisstudy
hasalsobeencompar edt oamikacinandgentamy cinwher ei
nisepamy cinwasf oundtohav e
maximum suscepti
bil
ityagainstEcolii
nuri
narysampl es.
Sosir,whenev eryoucomeacr oss
pati
entswhoaresufferingfr
om cUTIwi t
hE.Colibeingt hemainpathogen, werequestyout o
consi
derisepamyci
nf orthebestoutcomes.

Dose8t
o15mgperkgbodywei
ght

Si
r-i
fthepr
obl
em i
scUTII
Sepi
sthesol
uti
on

Thanky
ou

Hav
eni
cedaySi
r

Thanky
ou.