Indian Institute of Technology Bhubaneswar

School of Basic Sciences

B. Tech (Bioscience) Mid Semester Examination-2021

Subject Name: Introduction to Biosciences and Technology Code: ID2L002

Date: 15 / 09 / 2021 Semester: Autumn

Duration: 2 hours Full marks: 50

Instructions: Attempt all questions. Try to answer a new question on a fresh page (strictly) and all parts of a
question together. Draw all the structures / figures as clearly as possible. No extra materials required.
Cellphones not allowed.

Marks
Q1. (a) Name the protein that facilitate the simultaneous movement of both Na+ and K+ against [1+1]
their electrochemical gradients. (b) What is the approximate concentration of the sodium in
reference to the potassium inside the cell?

Q2. (a) What is the value of the resting transmembrane potential of the cell? (b) Why can the [1+1+1]
cells maintain a transmembrane potential? (c) Between EnzI and P-EnzII which one will have
high affinity for K+ ions?

Q3. (a) What are permeases? (b) What is the basic difference between active and passive [1+2+1]
transport across the membrane? (c) Give two examples of transporters?

Q4. (a) What is the average thickness of plasma membrane? (b) Name at least two phospholipids [1+2+2]
that are found in the plasma membrane. (c) Name the variety of aggregates that can be
formed by the phospholipids in water.

Q5. (a) How many chiral α-amino acids are commonly found in proteins? (b) Draw the chemical [1+6]
structure of the following amino acids (i) Tyr, (ii) Phe, and (iii) Trp and indicate, which one
of the above will undergo phosphorylation?

Q6. (a) Between a prokaryotic and eukaryotic cell, which one is usually larger in size. (b) What [1+1+1]
is the average size of a virus? (c) Give the example of a cell that has a branched structure.

Q7. (a) What is the basic difference between heterotrophs and organotrophs? (b) Indicate the [2+5]
function of the following in the context of the cell (i) Ribosome, (ii) Lysosome, (iii) Golgi
complex, (iv) Thylakoids, and (v) Mitochondrion

Q8. (a) Where can we find DNA in the cell? (b) Name the processes in which DNA is converted [1+2+5]
to RNA and subsequently to protein. (c) Briefly describe the “molecular logic of life”.

Q9. (a) How long an action potential typically last in neurons compared to regular muscle and [2+3+2]
heart. (b) What do you call a heart cell? Schematically illustrate the action potential of one
heartbeat. (c) What is the difference between the systolic vs. diastolic heart?

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Q10. (a) What is EEG and what is its usage? (b) Which cell contribute toward the measurement [2+2]
done by the EEG? What is the range of the electrical signal typically observed for brain?

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