The Citric Acid Cycle (Krebs Cycle)

Kreb’s Cycle Worksheet

1. Krebs cycle occurs in the ______________________________________________________

2. The overall purpose of Krebs cycle is to __________________________________________

3. What product of private oxidation enters the cycle? _________________________________

4. What happens to the coenzyme A (CoA) that is released? ____________________________

5. Why is Krebs cycle also called the citric acid cycle? ________________________________
6. What makes the Krebs cycle cyclic? _____________________________________________

2
7. How many times does the cycle take place per molecule of glucose? ___________________

reacts with oxaloacetate and form 6

8. What happens to the two carbons that enter the cycle as acetyl-CoA? ___________________
carbon citrate
nothing
9. At the end of the cycle, what is left of the original glucose molecule? ___________________

4
10. How many oxidations occur in one cycle? ______________

2
11. How many decarboxylations occur in one cycle? _______________

1
12. What is the number of NADH molecules yielded from each pyruvate? ____________ From each
2
glucose molecule? ____________

1
13. What is the number of FADH2 molecules yielded from each pyruvate? ____________ From each
2
glucose molecule? ____________

NAD doesn't reduce efficiently

14. Why is FAD used instead of NAD+? ____________________________________________

proceeds to electron transport chain

15. What happens to these electron carriers after Krebs cycle? ___________________________

1
16. How many ATP are produced from each pyruvate? ____________ From each glucose molecule?
2
____________

substrate level
17. What type of phosphorylation takes place to produce this ATP? _______________________