Drug Name Dosages Therapeutic Actions Indications Adverse effects Contraindicati Nursing considerations

side effects ons

Generic name: PO 5 mg 3 The exact mechanism • Oral baclofen is • Sedation, Hypersensiti
Baclofen times/day of action of baclofen is indicated for the drowsiness, vity. Active
for 3 days, unclear. treatment of ataxia, peptic ulcer Interventions
Brand name: increased spasticity dizziness, disease.
Fleqsuvy, to 10 mg Baclofen is an agonist resulting from headache, Give with caution to
Gablofen, TID for 3 at the beta subunit of multiple sclerosis confusion, patients whose spasticity
Kemstro, days. May gamma-aminobutyric and is particularly hallucinatio contributes to upright
Lioresal, further acid (GABA) useful for the ns, skin posture or balance in
Lyvispah, increase if receptors expressed on relief of flexor reactions, GI locomotion or whenever
Ozobax needed. pre- and post-synaptic spasms and symptoms, spasticity is used to
Max: 100 neurons.3 Upon concomitant pain, enuresis. increase function.
Drug mg/day. binding to clonus, and • Potentially
classification GABA receptors, muscular rigidity. Fatal: Teaching points: instruct
baclofen causes an It may also be Respiratory patient to do the ff;
• Centrally influx of potassium used to treat or CV
acting into the neuron, patients with depression, • Take this drug exactly
skeletal leading to spinal cord seizures. as prescribed. Do not
muscle hyperpolarization of injuries and other stop taking this drug
relaxant the neuronal spinal cord without consulting your
membrane and diseases. Baclofen health care provider;
decreased calcium should not be abrupt discontinuation
influx at presynaptic used to treat may cause
nerve terminals. This skeletal muscle hallucinations or other
results in a decreased spasms resulting serious effects.
rate of action potential from rheumatic • Avoid alcohol, sleep-
threshold being disorders inducing, or over-the-
reached by presynaptic counter drugs because
neurons and reduced these could cause
action potential of dangerous effects.
postsynaptic motor
neurons that innervate • Report frequent or
the muscle spindles painful urination,
constipation, nausea,
Baclofen is an headache, insomnia, or
antispastic. It inhibits confusion that persists
both monosynaptic
 and polysynaptic or is severe.
reflexes at spinal level.

GENERIC Route: • Inhibits Short term - CNS: Hypersensitivi Monitor BP upon

NAME: I.V prostaglandin management of 1) drowsiness y administration. < 90/80 never
Ketorolac synthesis, pain (not to 2) abnormal administer. Refer to doctor.
Dose: producing exceed 5 days thinking
BRAND Q 6h peripherally total for all routes 3) dizziness Crosssensitivi Assess pain (note type,
NAME: mediated combined) 4) euphoria ty with other location, and intensity) prior to
Toradol Dosage: analgesia 5) headache- NSAIDs may and 1-2 hr following
30mg • Also has - RESP: exist¨Pre- or administration.
CLASSIFI- antipyretic and 1) asthma perioperative
CATION: anti- 2) dyspnea use
Nonsteroidal inflammatory - CV:
anti- properties. 1) edema
inflammatory - Therapeutic 2) pallor Known Advise patient to consult if
agents, effect: Decreased 3) vasodilation alcohol rash, itching, visual
nonopioid pain - GI: intolerance disturbances, tinnitus, weight
analagesics 1) GI Bleeding Use gain, edema, black stools,
2) abnormal cautiously persistent headche, or
taste in: influenza-like syndromes
3) diarrhea 1) History of (chills,fever,muscles aches,
4) dry mouth GI bleeding pain) occur.
5) dyspepsia 2) Renal
6) GI pain impair-ment
7) nausea (dosage
- GU: reduction
1) oliguria may be
2) renal toxicity required)
3) urinary 3)
frequency Cardiovascu
lar disease