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QUIZ 1

Acetazolamide
Correct answers: Rectal Diazepam
6.The use of this drug should be with precaution in
patients with DM:. Single choice.
(1/1 Point)
1.Ganglionic blocker:. Single choice.
CBZ
Phenytoin
(1/1 Point)
Lamotrigine
Succinylcholine
VPA
Rocuronium
Correct answers: VPA
Hexamethonium 7.The first-line antidote for cholinergic poisons:. Single
choice.
Atracurium (1/1 Point)
Correct answers: Hexamethonium
2.Mixed alpha-beta blocker:. Single choice. Atropine
(1/1 Point)
Hysocine
Bisoprolol
PAM
Celiprolol
DAM
Carvedilol Correct answers: Atropine
8.Low doses of beta-blockers are indicated for Chinese
Nebivolol patients to prevent:. Single choice.
Correct answers: Carvedilol (1/1 Point)
3.Which of the following is good for geriatric patients?.
Single choice. Heart Block
(1/1 Point)
Bradycardia
Midazolam
Reflex Tachycardia
Alprazolam
Bronchospasms
Oxazepam Correct answers: Reflex Tachycardia
9.Beta-blocker for HTN in patients who are diabetic with
Diazepam CHF:. Single choice.
Correct answers: Oxazepam (1/1 Point)
4.Which of the following agents is good for arrhythmia
and hypertensive emergencies?. Single choice. Bisoprolol
(0/1 Point)
Celiprolol
Metoprolol
Carvedilol
Carvedilol
Metoprolol
Esmolol Correct answers: Carvedilol
10.Which of the following does not belong to the
Sotalol group?. Single choice.
Your answer to question 4 is wrong. Correct answers: (1/1 Point)
Esmolol
5.DOC for status epilepticus in children. Single choice. Rivastigmine
(1/1 Point)
Donepezil
Rectal Diazepam
Pyridostigmine
Phenytoin
Galantamine
Phenobarbital Correct answers: Pyridostigmine
11.Anti-seizure drug that necessitates hydration to
Analgesia
prevent kidney stones:. Single choice.
(1/1 Point) Eclampsia
Topiramate Diabetic nephropathy
Correct answers: Diabetic neuropathy
Lamotrigine
17.Pre-anesthetic:. Single choice.
Pregabalin (1/1 Point)
Gabapentin Thiopental
Correct answers: Topiramate
Secobarbital
12.Most common side effect of Phenytoin. Single
choice. Vinbarbital
(1/1 Point)
Phenobarbital
Hirsutism Correct answers: Thiopental
18.May cause blindness when myopia is clinically
Gingival hyperplasia
observed:. Single choice.
Ataxia (1/1 Point)
Diplopia Phenytoin
Correct answers: Gingival hyperplasia
Cenobamate
13.The first-line antidote for antimuscarinic agents:.
Single choice. Lamotrigine
(1/1 Point)
Topiramate
Neostigmine Correct answers: Topiramate
19.Antidote for Zolpidem poisoning. Single choice.
Atropine
(1/1 Point)
Rivastigmine
Ascorbic Acid
Physostigmine
Activated Charcoal
Correct answers: Neostigmine
14.Best cholinesterase inhibitor for MG:. Single choice. NaHCO3
(1/1 Point)
Flumazenil
Rivastigmine Correct answers: Flumazenil
20.DOC for Lennox-Gastaut Syndrome. Single choice.
Physostigmine
(1/1 Point)
Pyridostigmine
Lamotrigine
Neostigmine
Zonisamide
Correct answers: Pyridostigmine
15.DOC for Malignant Hyperthermia. Single choice. Rufinamide
(1/1 Point)
VPA
Dantrolene Correct answers: VPA
21.Which of the following is the best option for a
Bromocriptine
hypertensive patient with asthma?. Single choice.
Enflurane (0/1 Point)
Ryanodine Pindolol
Correct answers: Dantrolene
Carvedilol
16.Pregabalin is more ued for:. Single choice.
(1/1 Point) Celiprolol
Diabetic neuropathy Betaxolol
Your answer to question 21 is wrong. Correct answers:
Orphenadrine
Celiprolol
22.A novel lactate dehydrogenase inhibitor for seizures Biperiden
especially Dravet Syndrome:. Single choice.
(1/1 Point) Trihexyphenidyl
Correct answers: Orphenadrine
Cenobamate 27.Which of the following is used for urinary retention?.
Single choice.
Stiripentol
(1/1 Point)
Ezogabine
Bethanechol
Suvorexant
Methacholine
Correct answers: Stiripentol
23.DOC for absence seizures. Single choice. Pilocarpine
(1/1 Point)
Carbachol
Ethosuximide Correct answers: Bethanechol
28.Which of the following is the longest-acting agent
Topiramate
indicated for asthma?. Single choice.
VPA (1/1 Point)
Clonazepam Revefenacin
Correct answers: Ethosuximide
Tiotropium
24.For patients with bipolar disorders that failed to
respond to Lithium and Lamotrigine, this anti-seizure Oxytropium
drug can be used:. Single choice.
(1/1 Point) Ipratropium
Correct answers: Tiotropium
Topiramate 29.Alcohol dehydrogenase inhibitor used as an antidote
to methanol poisoning:. Single choice.
Carbamazepine
(1/1 Point)
Stiripentol
Ethanol
Felbamate
Acamprosate
Correct answers: Carbamazepine
25.Which of the following is the best option for a Fomepizole
hypertensive patient with angina?. Single choice.
(1/1 Point) Nalmefene

Metoprolol Disulfiram
Correct answers: Fomepizole
Propranolol 30.Which of the following is associated with allergic
reactions?. Single choice.
Acebutolol
(1/1 Point)
Labetalol
Vecuronium
Correct answers: Metoprolol
26.Antimuscarinic for Parkinsonism, except:. Single Rocuronium
choice.
(1/1 Point) Atracurium
Message for respondents who select this answer
Diphenhydramine
Pipecurium
Benztropine Correct answers: Atracurium
QUIZ 2
Morphinan
Piperidine
Benzomorphan
Correct answers: Morphinan
1.For inflammation of RA, the ASA daily dose should be:. 6.Oxaprozin. Single choice.
Single choice. (1/1 Point)
(1/1 Point)
Naphthylacetic Acid
3.2-4g/day
Indole Acetic Acid
<0.325g/day
Propionic Acid
< 0.6g/day
Phenylacetic Acid
0.3-2.4g/day
Correct answers: 3.2-4g/day Pyrrole Alkanoic Acid
2.The only opioid with a mixed agonist-antagonist Correct answers: Propionic Acid
activity that is a dominant mu agonist:. Single choice. 7.Which of the following possess an analgesic effect
(1/1 Point) comparable to opioids? I. Etodolac II. Ketorolac III.
Sulindac. Single choice.
Nalbuphine (1/1 Point)
Buprenorphine II & III
Pentazocine I & III
Butorphanol III
Correct answers: Buprenorphine
3.Antipyrine:. Single choice. I
(1/1 Point) I & II
N-arylanthranilic Acid Correct answers: I & II
8.Which of the following is considered the most
Salicylate nephrotoxic?. Single choice.
Arylacetic Acid (0/1 Point)

Pyrrazolone Naproxen
Correct answers: Pyrrazolone Mefenamic Acid
4.What is the chemical class of Nalbuphine?. Single
choice. Piroxicam
(1/1 Point) Ketorolac
Phenylheptylamine Your answer to question 8 is wrong. Correct answers:
Naproxen
Piperidine 9.What is the action of Morphine for acute pulmonary
Benzomorphan edema and acute myocardial infarction?. Single choice.
(1/1 Point)
Phenanthrene
Venous dilation
Morphinan
Correct answers: Phenanthrene Arteriolar dilation
5.What is the chemical class of Levallorphan?. Single Reduces pain
choice.
(1/1 Point) Increases fluid output
Correct answers: Venous dilation
Phenylheptylamine 10.Sufentanil:. Single choice.
Phenanthrene (1/1 Point)
Full Agonist I & III
Antagonist II & IV
Mixed Agonist-Antagonist I & IV
Mild to Moderate Agonist III
Correct answers: Full Agonist
II & III
11.What is the chemical class of Diphenoxylate?. Single
Your answer to question 15 is wrong. Correct answers: II
choice.
& III
(1/1 Point)
16.Which of the following is not good for primary
Phenylheptylamine dysmenorrhea?. Single choice.
(1/1 Point)
Phenanthrene
Mefenamic Acid
Piperidine
Message for respondents who select this answer Diclofenac Potassium
Benzomorphan Naproxen
Morphinan Ibuprofen
Correct answers: Piperidine
Etodolac
12.Levorphanol. Single choice.
Correct answers: Etodolac
(1/1 Point)
17.Good for painful biliary colic:. Single choice.
Mixed Agonist-Antagonist (1/1 Point)
Full Agonist Fentanyl
Antagonist Nalbuphine
Mild to Moderate Agonist Pethidine
Correct answers: Full Agonist
Methadone
13.Opioid used as an emetic:. Single choice.
Correct answers: Pethidine
(1/1 Point)
18.If a patient can't receive Morphine for acute
Levallorphan pulmonary edema, the substitute is:. Single choice.
(1/1 Point)
Levomethadone
Furosemide
Apomorphine
Pethidine
Meperidine
Correct answers: Apomorphine Methadone
14.Nabumetone. Single choice.
Nalbuphine
(1/1 Point)
Levorphanol
Naphthylacetic Acid
Correct answers: Furosemide
Phenylacetic Acid 19.If a patient is allergic to Naproxen, he/she will most
definitely be allergic to:. Single choice.
Pyrrole Alkanoic Acid
(1/1 Point)
Propionic Acid
Diclofenac
Indole Acetic Acid
Nabumetone
Correct answers: Naphthylacetic Acid
15.Which of the following agents is/are more used for Piroxicam
alcohol withdrawal? I. Naloxone II. Naltrexone III.
Propyphenazone
Nalmefene IV. Nalorphine. Single choice.
Correct answers: Nabumetone
(0/1 Point)
20.What is the chemical class of Noscapine?. Single (1/1 Point)
choice.
Meperidine
(1/1 Point)
Pentazocine
Morphinan
Levorphanol
Benzomorphan
Methadone
Phenanthrene
Morphine
Piperidine
Correct answers: Pentazocine
Phenylheptylamine 26.The main reason why ASA is no longer generally used
Correct answers: Phenylheptylamine as an antipyretic:. Single choice.
21.Butorphanol. Single choice. (1/1 Point)
(1/1 Point)
Erosive Gastritis
Full Agonist
Allergic Reaction
Mild to Moderate Agonist
Reye's Syndrome
Mixed Agonist-Antagonist
Asthma
Antagonist Correct answers: Reye's Syndrome
Correct answers: Mixed Agonist-Antagonist 27.Diflunisal. Single choice.
22.Tolerance to opioid is expected for all of its effects, (1/1 Point)
except for:. Single choice.
Pyrrazolone
(1/1 Point)
N-arylanthranilic Acid
Nausea and Vomiting
Salicylate
Pruritus
Message for respondents who select this answer
Increased Intrcranial Pressure
Arylacetic Acid
Urinary Retention Correct answers: Salicylate
28.Tramadol. Single choice.
Constipation
(1/1 Point)
Correct answers: Constipation
23.Meclofenamic Acid. Single choice. Antagonist
(1/1 Point)
Mixed Agonist-Antagonist
Pyrrazolone
Mild to Moderate Agonist
Arylacetic Acid
Full Agonist
Salicylate Correct answers: Mild to Moderate Agonist
29.An opioid with an analgesic effect dominantly
N-arylanthranilic Acid
depending on the drugs ability to increase
Correct answers: N-arylanthranilic Acid
noradrenaline and serotonin:. Single choice.
24.Levallorphan. Single choice.
(1/1 Point)
(1/1 Point)
Tramadol
Antagonist
Apomorphine
Full Agonist
Ziconotide
Mild to Moderate Agonist
Nalorphine
Mixed Agonist-Antagonist
Correct answers: Tramadol
Correct answers: Antagonist
30.Tolmetin. Single choice.
25.The only prototypical opioid that is not a strong/full
(1/1 Point)
agonist:. Single choice.
A: <0.325 g/day
Naphthylacetic Acid
Indole Acetic Acid A cancer patient was maintained fentanyl for his
breakthrough pain (9 on pain scale). The head physician
Propionic Acid of the pain management team added Naloxone. What is
Phenylacetic Acid the right course of action?

Pyrrole Alkanoic Acid A: No intervention is required, the physician is trying to


Message for respondents who select this answer control for the toxic effects of fentanyl

If a hypertensive patient is to be administered with a


beta blocker, and the physician feels that it may or may
not adequately control the patient’s blood pressure,
which of the following agents will you suggest because
it is less associated with reflex tachycardia when
withdrawn or discontinued abruptly if this physician
decides to change or shift the therapy along the course

PRELIM
of the disease?

A: Acebutolol

Which of the following statements about Aspirin is


true?

EXAM
I. ASA is an irreversible inhibitor of lipoxygenase
preventing the biosynthesis of PG and TXA2
II. ASA is classified as an antiplatelet drug/platelet
aggregation inhibitor.
III. ASA is administered at 3.2 to 4g/day for
inflammation due to gout arthritis

Which of the following statement/s is/are true A: I


regarding phenytoin?
I. The drug is poorly water-soluble hence it may cause Which of the following is an unconventional antagonist
irritations at the injection site. in the sense that from a structural standpoint, it is
II. The solvent used for the parenteral formulation can indeed a morphinan derivative with excellent opioid
cause cardiac depression hence the infusion rate of antagonistic actions?
such should be controlled.
III Phenytoin in itself can also cause cardiac depression A: Levallorphan
and the early signs of toxicity are ataxia and diplopia.
What is the role of beta-blockers in the management of
A: I, II, III thyrotoxicosis?
I. Beta-blockers can inhibit the peroxidase-catalyzed
What is the mechanism of skeletal muscle paralysis reaction in the synthesis of thyroid hormones.
associated with succinylcholine? II. Beta-blockers control the sympathetic symptoms of
hyperthyroidism.
A: Sustained depolarization of the motor endplate III. Beta-blockers may inhibit the peripheral conversion
making it unresponsive to other impulses of T4 to T3.

A medical technologist has a 65 y/o father who recently A: II, III


suffered from a heart attack 3 days ago. What dose
range will you suggest to him to purchase when he visits NSAIDs are generally weak acids in vitro, but this NSAID
the pharmacy? is an exception
A: nabumetone
This is a sample drug discovered by screening of higher
Which of the following correctly explains the advantage plants which remains to be the gold standard in the
of beta-blockers with intrinsic sympathomimetic management of pain.
activity? A: morphine
I. These agents are relatively safe for patients with
bronchospastic disease. What is the primary drawback with the use of selective
II. These agents have anti-arrhythmic properties. COX-2 inhibitors?
III. These agents are less associated with rebound HTN A: greater incidence of thromboembolism
compared with other beta blockers.
A patient was rushed to the hospital and his blood
A: III pressure reading was 180/110 and his mean arterial
pressure is 133 mm/Hg but no organ damage was noted
This is a sample drug discovered by accident and a diagnosis of hypertensive emergency was then
made. In order to lower the mean arterial pressure
A: penicillin rapidly by 25%, which of the following must be
initiated?
Which of the following statements accurately describes
why the study of organic medicinal more dominant over I. Carvedilol
inorganic agents?
II. Acebutolol
A: Organic compounds like natural products are
abundant
III. Labetalol
A: I, III
A Filipino-chinese patient was prescribed to maintain
A female patient was admitted to the emergency room
metoprolol for the prevention of symptom
for the rapid lowering of her blood pressure to normal
exacerbations of his heart failure. The dose of
ranges. The patient has no other significant histories
metoprolol for this patient should be lower than the
except for an asthmatic attack when she was 8y/o.
dose due to ______________
There were no available IV infusions of NTG and
A: Reflex tachycardia
nitroprusside in your pharmacy nor short-acting IV
calcium channel blocker. Which of the following can be
A 10 yr old patient was reported to exhibit lapses in
used to lower this patient’s BP?
concentration that usually lasts for seconds with sudden
A: Labetalol
stops in motion and lip-smacking but without confused
states. With declining ability to learn. Neurologist
Tacrine, donepezil, & galantamine are anti-
confirms diagnosis of epilepsy. Which agent is
acetylcholinesterases employed for which of the
appropriate?
following conditions?
A: Topiramate
A: Alzheimer’s disease
A cancer patient is suffering from chronic breakthrough
TCAs have cardio-toxic and anticholinergic effects. For
pain and is now poorly responding to morphine and
the cardio-toxic effects, this drug can be administered.
fentanyl. What should be suggested to be added to the
A: Sodium bicarbonate
patient’s regimen?
A: ketorolac
Which of the following is the most recently developed
opioid antagonist approved for alcohol withdrawal by
A patient was admitted to the emergency due to severe
decreasing the patient’s craving for alcohol?
acute CHF and was prescribed medications for his CHF.
A: Nalmefene
Pulmonary findings are consistent of acute pulmonary
edema secondary to his acute CHF. If the patient has no
To confirm the diagnosis of asthma in the patient:
risks for developing respiratory depression, which can
A: methacholine
be recommended for the management of acute
pulmonary edema?
Which beta-blocker has K+ channel blocking effects
A: morphine
making it useful as an antiarrhythmic agent?
A: Sotalol
Receptors
This inorganic compound remains to be the gold Correct answers: Reuptake Proteins
standard for the treatment of mania and other related
bipolar disorders. 2.Which of the following is/are true regarding lipid-
A: Lithium carbonate water partition coefficient? I. The system being
used mimics the lipid membranes and the aqueous
The physician who discovered penicillin systems found in the body. II. The higher the lipid-
A: A. Fleming water partition coefficient, the more polar is the
drug. III. This parameter is usually determined to
Amantadine is an example of a drug where an determine hydrophobicity.. Single choice.
additional use is discovered by careful observation of its
(-/1 Point)
pharmacologic property.
A: Parkinson II, III

It is the most widely used acetylcholinesterase inhibitor


I, II
for myasthenia gravis. I, III
A: Pyridostigmine
I
Which of the following statement/s is/are true? I, II, III
I M3 receptors are Gq-linked receptors that lead to Answer: ?
activation of adenylyl cyclase, a signaling cascade that
leads to increased cAMP activity
3.A highly protein-bound drug that presents a
II M2 receptors are Gi-linked receptors that lead to
inhibition of PLC, a signaling cascade that decreases IP3 danger to patients when co-administered with
and DAG activity. another highly protein-bound drug since the
III M1 receptors are Gq-linked receptors that lead to displacement of this drug from its protein binding
activation of PLC,a signaling cascade that increases IP3 sites may cause hemorrhage.. Single choice.
and DAG activity. (1/1 Point)
A: III
Phenytoin
Which of the following conditions confer toxicity due to Oxacillin
organophosphates?
A: emesis Penicillin
Warfarin
Amitryptiline
Correct answers: Warfarin
MIDTERM QUIZ 1 4.Match the drug/drug group to the corresponding
target: (Recall of Pharmacology 1) Antipsychotics.
Single choice.
1.Match the drug/drug group to the corresponding
(1/1 Point)
target: (Recall of Pharmacology 1) TCA's. Single
choice. Enzymes
(1/1 Point) Carrier proteins
Enzymes Voltage-gated ion channels
Carrier proteins Receptors
Voltage-gated ion channels Structural proteins
Reuptake Proteins Correct answers: Receptors
5.E & Z isomerism is important for the activity of
Carrier proteins
this drug:. Single choice.
Correct answers: Voltage-gated ion channels
(1/1 Point)
Morphine 9.Match the drug/drug group to the corresponding
target: (Recall of Pharmacology 1) Digoxin. Single
Clomiphene
choice.
Methylphenidate (1/1 Point)
Diethylstibestrol Receptors
Omeprazole Carrier proteins
Correct answers: Clomiphene
Structural proteins
6.Match the drug/drug group to the corresponding Voltage-gated ion channels
target: (Recall of Pharmacology 1) Paracetamol.
Enzymes
Single choice.
Correct answers: Carrier proteins
(1/1 Point)
Receptors 10.Match the drug/drug group to the
corresponding target: (Recall of Pharmacology 1)
Carrier proteins
Cocaine. Single choice.
Enzymes (1/1 Point)
Structural proteins Enzymes
Voltage-gated ion channels Carrier proteins
Correct answers: Enzymes
Reuptake Proteins
7.Match the drug/drug group to the corresponding Receptors
target: (Recall of Pharmacology 1) Moclobemide.
Voltage-gated ion channels
Single choice.
Correct answers: Reuptake Proteins
(1/1 Point)
Carrier proteins 11.Sample drug excreted via the saliva. Single
choice.
Reuptake Proteins
(1/1 Point)
Voltage-gated ion channels
Nafcillin
Receptors
Chloramphenicol
Enzymes
Levobupivacaine
Correct answers: Enzymes
Lidocaine
8.Match the drug/drug group to the corresponding
Procaine
target: (Recall of Pharmacology 1) Carbamazepine.
Correct answers: Lidocaine
Single choice.
(1/1 Point)
12.Match the drug/drug group to the
Structural proteins corresponding target: (Recall of Pharmacology 1)
Omeprazole. Single choice.
Receptors
(1/1 Point)
Enzymes
Carrier proteins
Voltage-gated ion channels
Enzymes
Voltage-gated ion channels Receptors
Receptors Structural proteins
Structural proteins Voltage-gated ion channels
Correct answers: Carrier proteins
Carrier proteins
13.Which of the following drug groups have Enzymes
mechanisms of action that involve binding to Correct answers: Structural proteins
enzymes as target proteins?. Single choice.
(1/1 Point) 17.Match the drug/drug group to the
corresponding target: (Recall of Pharmacology 1)
Barbiturates
Local Anesthetics. Single choice.
BZD's (1/1 Point)
Calcium Channel Blockers Receptors
NSAID's Enzymes
Phenothiazines Voltage-gated ion channels
Correct answers: NSAID's
Carrier proteins
14.Which of the following is not true regarding the Structural proteins
intravenous route of administration?. Single choice. Correct answers: Voltage-gated ion channels
(0/1 Point)
18.Match the drug/drug group to the
Excretion is quite rapid.
corresponding target: (Recall of Pharmacology 1)
Metabolism is quite rapid. Flibanserin. Single choice.
(1/1 Point)
Absorption does not occur.
Voltage-gated ion channels
Protein binding does not occur.
Carrier proteins
It avoids first pass-effect.
Your answer to question 14 is wrong. Correct Structural proteins
answers: It avoids first pass-effect.
Enzymes
15.Match the drug/drug group to the Receptors
corresponding target: (Recall of Pharmacology 1) Correct answers: Receptors
Phenytoin. Single choice.
(1/1 Point) 19.The following are the general factors that affect
a dug molecule’s binding to a receptor except:.
Carrier proteins
Single choice.
Structural proteins (1/1 Point)
Enzymes Chemical bonding capabilities
Receptors Structural class
Voltage-gated ion channels 3D-shape of the molecule
Correct answers: Voltage-gated ion channels
Type of dosage form
16.Match the drug/drug group to the
Correct answers: Type of dosage form
corresponding target: (Recall of Pharmacology 1)
Colchicine. Single choice.
(1/1 Point)
20.A given drug was found to mimic Acetylcholine 23.A functional group or organized group of
since it contains the same number and molecules that interact with the drug to produce a
arrangement of electrons in one region of the biological response is known as ____________..
molecule. The molecule was observed to exert a Single choice.
cholinergic effect more selectively. Which of the (1/1 Point)
following statement(s) correctly describes this drug
Active site
molecule? I. The drug is an isostere of the
neurotransmitter Acetylcholine. II. The drug is an Receptor site
analogue of Acetylcholine that blocks its binding Biological receptor site
from its receptors. III. The drug is an analogue that
agonizes Acetylcholine receptors.. Single choice. Biological site
(0/1 Point) Correct answers: Biological receptor site

I, II, III 24.Match the drug/drug group to the


I, III corresponding target: (Recall of Pharmacology 1)
Levodopa. Single choice.
I
(1/1 Point)
I, II
Receptors
II, III
Voltage-gated ion channels
Your answer to question 20 is wrong. Correct
answers: I, III Reuptake Proteins
Enzymes
21.Match the drug/drug group to the
corresponding target: (Recall of Pharmacology 1) Carrier proteins
Morphine. Single choice. Correct answers: Receptors
(1/1 Point)
25.Which of the following statement/s regarding
Receptors acetylcholine is/are true? I. The quasi-ring
Voltage-gated ion channels structure is the pharmacophore at Nicotinic
receptors causing CNS stimulation. II. The extended
Reuptake Proteins
structure is the pharmacophore at Nicotinic
Carrier proteins receptors causing CNS stimulation. III. The quasi-
ring structure is the form in which acetylcholine is
Enzymes
recognized and degraded by acetylcholine
Correct answers: Receptors
esterases.. Single choice.
(1/1 Point)
22.ASA irreversibly binds COX hence it utilizes this
bond for binding:. Single choice. I, II
(1/1 Point)
I
VDW forces
II, III
Disulfide bonds
I, III
H-bonds
I, II, III
Covalent bonds Correct answers: I, III
26.Match the drug/drug group to the
Ionic bonds
corresponding target: (Recall of Pharmacology 1)
Correct answers: Covalent bonds
Methotrexate. Single choice.
(0/1 Point)
Correct answers: I, II
Enzymes
Structural proteins 30.Chloramphenicol for suspensions is formulated
Voltage-gated ion channels as palmitate salts to:. Single choice.
(1/1 Point)
Carrier proteins
To enhance oral absorption
Receptors
Your answer to question 26 is wrong. Correct To mask the bitter after-taste of the drug
answers: Receptors To enhance biliary recycling
To improve solubility in GIT
27.Sample drug excreted via the breast milk. Single
choice. To bypass first pass effect
(1/1 Point) Correct answers: To mask the bitter after-taste of
the drug
Chloramphenicol
Levobupivacaine 31.Sample drug marketed in its racemic combined
Procaine R & S forms:. Single choice.
(1/1 Point)
Lidocaine
Ephedrine
Nafcillin
Correct answers: Chloramphenicol Naproxen
Bupivacaine
28.Match the drug/drug group to the
Dextromethorphan
corresponding target: (Recall of Pharmacology 1)
Atracurium. Single choice. Ibuprofen
(0/1 Point) Correct answers: Ibuprofen
Carrier proteins
32.The most potent isomer of Methylphenidate is:.
Structural proteins Single choice.
Receptors (0/1 Point)

Voltage-gated ion channels dextro-threo

Enzymes threo
Your answer to question 28 is wrong. Correct erythro
answers: Receptors
levo-threo
29.Which of the following functional groups is/are S
capable of forming ionic bonds with the receptor? Your answer to question 32 is wrong. Correct
I. Carboxyl Groups II. Sulfonamido Groups III. answers: dextro-threo
Hydroxyl Groups. Single choice.
(1/1 Point) 33.Which of the following regarding isosterism
is/are true? I. Isosteres impart similar physical
I, II
properties but ultimately different chemical
II, III properties in drug molecules. II. Isosteric
I, III alterations are widely employed in discovery of
analogues or antagonists to normal metabolites. III.
I, II, III Isosteres are compounds or groups of atoms with
I
the same number and arrangement of electrons..
Enzymes
Single choice.
Correct answers: Receptors
(1/1 Point)
I 37.Match the drug/drug group to the
corresponding target: (Recall of Pharmacology 1)
I, II
Clonidine. Single choice.
I, II, III (1/1 Point)
I, III Structural proteins
II, III Enzymes
Correct answers: II, III
Voltage-gated ion channels
34.Match the drug/drug group to the Carrier proteins
corresponding target: (Recall of Pharmacology 1)
Receptors
Benzodiazepines. Single choice.
Correct answers: Receptors
(1/1 Point)
Enzymes 38.Van der Waals Forces of attraction are essential
for this group’s interaction with receptors:. Single
Structural proteins
choice.
Voltage-gated ion channels (-/1 Point)
Carrier proteins Imines
Receptors Benzene
Correct answers: Receptors
Carbonyl
35.Match the drug/drug group to the Amines
corresponding target: (Recall of Pharmacology 1)
Aliphatic
Caffeine. Single choice.
Answer: ?
(1/1 Point)
Receptors 39.Which of the following statement(s) is (are)
true? I. DES is active in its cis-configuration. II. Levo
Structural proteins
isomers of opioids in general are active as
Voltage-gated ion channels analgesics. III. All isomers of the opioid analgesics
Enzymes are good antitussives.. Single choice.
(1/1 Point)
Carrier proteins
Correct answers: Enzymes I & III
II
36.Match the drug/drug group to the
I
corresponding target: (Recall of Pharmacology 1)
Loratadine. Single choice. II & III
(1/1 Point)
III
Receptors Correct answers: II
40.Match the drug/drug group to the
Carrier proteins
corresponding target: (Recall of Pharmacology 1)
Structural proteins Eicosanoid Analogues. Single choice.
Voltage-gated ion channels (1/1 Point)
44.Which of the following is/are true regarding
Receptors
some of the stereoisomeric features of drugs? I. S-
Enzymes omeprazole has a longer half-life compared to the
Structural proteins combination of R & S enantiomers of Omeprazole.
II. Dextrorotatory bupivacaine is more potent than
Carrier proteins levo and dextro bupivacaine. III. Dextrorotatory
Voltage-gated ion channels isomers of opioid analgesics are excellent
Correct answers: Receptors antitussives.. Single choice.
(1/1 Point)
41.This parameter determines a drug’s ability to II, III
permeate aqueous and lipid barriers of the
different body compartments.. Single choice. II
(1/1 Point) III
Lipid Water Partition Coefficient I, II, III
Creatinine Clearance I, III
t1/2 Correct answers: I, III

Vd 45.Match the drug/drug group to the


Lipid-Water Concentration corresponding target: (Recall of Pharmacology 1)
Correct answers: Lipid Water Partition Coefficient SSRI's. Single choice.

42.Match the drug/drug group to the


(1/1 Point)
corresponding target: (Recall of Pharmacology 1)
Physostigmine. Single choice. Reuptake Proteins
(1/1 Point) Carrier proteins
Voltage-gated ion channels Enzymes
Enzymes Voltage-gated ion channels
Carrier proteins Receptors
Receptors Correct answer: Reuptake proteins
Structural proteins
Correct answers: Enzymes

43.Match the drug/drug group to the


corresponding target: (Recall of Pharmacology 1)
Allopurinol. Single choice.
(1/1 Point)
Structural proteins
Voltage-gated ion channels
Enzymes
Receptors
Carrier proteins
Correct answers: Enzymes

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