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72 Blood pH Acidosis
ph imoalanr e heruld home F6s
These findings are correlatedBun(t)
8un rst/N
with enum
whichtracopditionn On trra t Unc aua f - meabolic audtis
b. Pre-rënal azotemia elyc . Renal azotemia.1 eee res d Diabetic ketoacidosis
aost-renalazótemia tnue nenti diveude (6)
C2., Inverted albumin to globulin ratio in plasma is seen in what condition? tbun 1han qtsbuin naed
a. Nephrosis ohunin b. Pulmonary emphysema c. Multiple myeloma d. Meningitis gava i e
aulrtuan ().
b 3. Apotent cardiactoxin with the cápacitý to cross the placenta and mammary gland;
a. Morphine 6 . Cocaineecaf en c. Amphetaminesunautt d. Maruana4C aays
arcliac wai, POnaro phaeng tre ament For narcoleas
a 4. What is the plasma concentration of cholesterol and triglyceride in hypothyroidism and hyperthyroidis ni,
respectively? Ia I y
-
nuolnd in
meta brhim 7s
a. Increased, decreased b. Decreased, increased c. Both increased d. Both dcreased
Pteudo hperkakmia
a 5. A phlebotomist performed multi-draw from a 32 year-old male patient with thrombocytosis, Laboratory
request includes CBC with platelet count, repeat potassium, and ALT, During colleetion of blood.er
gold.
green and lavender top were used, respectively. Was the order of draw correct?
tp oiat
a. Yes, green top is preferred for potassium in patients with thrombocytosis fube
b. Yes. gold top is for ALT and potassium while green top is a reserved specimen for chemistry
c No, the order of draw will cause pre-analytical error tpoturt am nd 1et Krchug Funcna
d. No, the order of draw will cause analytical error
Ppidare y oe - decarboxylase
6. Which of these enzymes is a hydrolase?K -eneept aldota4e 4. C K ranuperceye
7 . The following results are obtained after analyses: Cmirms ndaor t (nfirma
FBG 118 mg/dL impaitd guMare (2-hourOGTT) 212 mg/dL
These results are consistent with: 190 -199 ng idt
poka hal 0M
a. Non-DM < jn
C. Impaired glucose tolerance i - 1Rf ma ld!
b. Type 2 DM * 126 d. Incomplete fasting specimen
vyr/emah c errur
8. A shift in the mean value indicates an error concerning which QC parameter?
a. Precision /wpvdua prut b. Accuracy c. Detection limit /ventinvity d. Specificity
9. In the Westgard multiple rules, what is the meaning of 10x selcw er a e r mean vauue
a. 10 consecutive control values are al above the mean due to random errors
b. 10 consecutive control values are all below the megn due to systematic errors
c. 5 consecutive control values are above the mean while 5 consecútive control values are below the mean in a 10-
day period
d. 5 consecutive control values are above the mean while any 5 control values are below the mean in a 30-day
Magnesum an y
l n type 1 hyperlipoproteinemin, which of the following is elevated in plasma after 12-hour fasting? Lpop sPn
Pephh
1. Chylomicrons yraie dtivJ chy1 nutn
2. VLD1?' (hyfonutn 3 Exogenous triglycerides 4 Endogenous triglyceride
a 1,3 b 1.4 c2,f d 2.4
.
This disorder is characterized by elevated plasma concentration of ACTH:o ord Mhuutrt
d odisease
a. Addison.s me b. Cushing's discasec hyhroylaj rum
c. Congenitál adrena hyperplasia d Neuroblastoma
18. Which of íhe following plots is best for comparing one laboratory's precision and accuracy to other
laboratorics using the same test serum but different methods?
a. Levy-Jennings b. Tonks-Youden c Cusum r -end d Gaussian Curve
ga aMd mahiat
19.True of random errors, exceptnt twnpicr nrma/
7 d Graves disease
d
O
d
edetn c ne Auhmmunn
b25. 1his iHlicit drug is used for treatment of narcolepsy:
oddi cr
e
td
a. Heroin -M b. Amphetamine c. Phencyclidine d Phenobarbirai
angit dut
b 26. To illustrate a Levey-Jennings chart, which of the following is a requirement?
a Weekly analysis of the control sera for 30 days
b. Analyses of the control sera for 20 consecutive days
c. 20 times analyses of the control sera every day for 30 days
d. Analyses of control sera must be done by one and the same person for 30 days
2 7 I t measures average blood glucose level: d mnhs
a. FBS b. 2-hour OGTT c. HbAlc d 2-hour post prandial
d28. Measurement ofthis analyte using 24-hour urine is considered the diagnostic test for pheochromocytoma:
a.Cathecholamines (pirdb. Homovanillic acid c. VMA umpln$tana d Metanephrines >
ubiutm met abundant Naiia ns
29Major protein found in HDL: mermbri
a Apo B-100 b. Apo H c. Apo A-1 d Apo B-48
30. All factors are included in the quality assessment program ofthe laboratory, except:
a. Preventive maintenance of instruments c. Specimen collection
b. Duty schedules of staff d. Internal QC test
31. Increased exposure to this toxic substance may result to ADHD and low 1Q:
a. Cyanide 6 ammd D. Mercury tnu nvimun C Arsenic - mata K
d Lead
Fus et uhny twai
3 2 . True of anion gap, except: d ut prura Aer
e
a. Used as a QC for electrolyte analyzer 16f
y (an (itrs ploen
b. Renal failure is one the causes ofincreased AG
Potassiumfis always included in the calculation
d . Serum levels of sodium, chloride and bicarbonate are needed
33. Which of these enzymes may be requested to determine skeletal muscle injury?
1. CPK-3 chmm 2. AST 3. LDH-4 4 AldolaseA
d1.2,3.4
a. I
only L#1 nude b. 1, 2
cI2,3
marker
mark t N
* KESA RODRI GUE z LEMAR REVIEW HUB 6 3 94 79 5 3
6066 P a g
4Which of thege hormones are the Down syndrome markers? 2, d ,+
AFP-vhin ngh
a. I only Aammne but
2. HCG 3. Estriol 4 Inhibin-A
marker b. 1,2 c 1,2,3 d. 1,2, 3. 4
35. This NPN when
increased in plasma is neurotoXIC
a. Creatinine Ureamet o b u n ea n
reabsorbed: 4n nrnma
a.
Beta 2-microglobulin b. Cystatin C ER c. Alpha-2 macroglobulin d. Urea
d 37. This cardiac marker rises an hour after infarction and returns to its normal plasma level within 24 hours:
Troponin I npr
a. b. Troponin T- fr
-
44. In therapeutic drug monitoring, which statements is correct regarding peak concentration?
of these
a. Specimen is collected usually an one hour after an orally administered dose
b. The peak blood sample is the best specimen for initial investigation of therapeutic drug toxicity
c. Both
eak min art dimsNah ihwws qexd tmh30muns B
d. Neither NAT drge
45. In anencephaly, this soluble substance increases in the plasma of pregnant women: w
acithin arenee b. Alpha fetoprotein c. Beta HCG d. Progesterone
prhn or graun
C 46. Test for pesticidepoisoning:
a. 5' nucleotidase -r okstuctive jaunduce, . Pseudocholinesterase
b. Angiotensin converting enzyme d. Ormithine carbamoyl transferase
d 47. Timed specimens are ordered for a variety of reasons, and usually to monitor changes:
1. In a patient's condition #es
2. To determine the level of a medication TON
wnang uM
a
Electrophoresis -m b.Gas chromatography $ c
()ens
Fluorometry, d AAS -d'toeho
b57. Which of the following QC charts is utilized for intraquality contröl testing?
1. Levey-Jennings 2. Westgard 3. Gaussian 4Cus
a 1 only
b.1,2 c1,2,3 d 1,2.3,4
5 8 This
finding is useful in the detection
of early glomerular dysfunction
a. Elevated serum creatinine c. Microalbuminuria - t m
b. Decreased inulin clearance d Hematuria
59,An hypoglycemia, Whipple's triad is characterized by:
1. Blood glucose less than 60 mg/dLL 3. Intake of glucose to reduce symptoms
2. Neuroglycopenic symptoms(60 S5) 4. IV administration of glucose to promptly arrest hypoglycemia
a 1 only b. 1,2 c.1,2,3 d. 1,2,3, 4
6 0 . Indirectly measures the binding capacity of TBG m e T n d turetion tT8
a. Modified Van Handel and Zilversmith Ta cAbell, Levy and Brodie 3 dp mnunre pe rolium hepane
b76. This hormone secreted by theparafollicular cells affects plasma calcium level by inhibiting PTHand
vitamin D synthesis: Cees
c. Activated vitamin D3 d. Gastrin Tumar mer her
a. Parathyroid hormone b. Calcitonin
d 77. The following are currently considered routine methods in chemistry laboratory, except:
a Cholesterol oxidase c. Hexokinase
b. Glycerol kinase d. Uricase and glutamate dehydrogenase
78. This reaction measures the formation of purple azobilirubin: gw- ens
a. Fearon reaction -BUM) c. Van den Berg reaction eu ma
d. Zimmerman reaction - i Ketvzpnnw d e n
b. Berthelotreaction- Ammoru
a 79. Which of these tubes is the choicefor compatibility testing? had
r r
a. Pink top b. Oránge top c. Lavender top d. Brown top
eAi
80. In dry slide technology, the preferred method for measuring analytes:
a. PCR b. Nephelometry c. Fluorometry d. Reflectance photometry
-sut er
81. The degree of correspondence between the obtained value and the true value:
a. Accuracy b. Reliability: auurn c. Precision d. Reproducibility
preu
82. This analgesic is an inhibitor of Kreb's cycle and considered toxzic:
a Acetaminophen b. Phenylpropnolamine c. Aspirin d. Tylenol
c83. ThHiet drug can cause lossotintelfectual functions among chronic users and can be detected for up to
45 days: tdat n
8 4 . Iu involves measurement of a single test on each sample loaded at the same time:
a. Random access b. Sequential c. Batch d. Parallel
B U r
d 85. Bone and liver ALP are both inhibited by this reagent: -bome Lin
body:
a. AST b. ALP
IkD
d. CPK
1SE (lettiy/Ha
87. It is used for measurement of p02: '
PCO2
c. Coulometry - u a chlonde d. Polarography
a. Amperometry b. Potentiometry
a 88. Which of these enzymes is classified as a lyase: Sunpa
1. Aldolase 2. 5 nucleotidase 3. Pepsin, yoru 4. Creatine kinase
a. 1 only b. 1,2 yairtase(evierne) c. 1,2,3 peptiets d. 1, 2,3,4
89. For serum cholesterol level,> 240 mg/dL and > 260 mg/dL fall under which category, respectively?
a. Borderline and hypercholesterolemia 00- a31 c. Moderate risk and high risk
b. Low risk and moderate risk d. Immediately requires medical intervention
90. It is based on the attachment ofthe substrate to the active site of the enzyme:
a. Kochland b. Wrobleuski c. Rayleigh d. Emil-Fisher
iut Scdtcr p pu -Lock Ku
A MA TERE SA RODRI GUE Z LEMAR REVI EW HUB +63 9 4795 6 0660 Page
91 Substrate for measurement of lipase
a Starch activity: TMPPhospheruse : 1c 2/tu
b. Triolein c. Lactate d. Thymolpthalein monophosphate
92. The following causes artifactual hyperkalemia, except: PPNP
a. Thrombocytosis
c. Fist clenching
b. Acidosis
d. High blast count seen in leukemia hermokalema
d93. Ater serum
electrophoresis, which protein is present in the alpha-1 Lnikalnss
. Haptoglobin
globulin region
2. Albumin 3. Ceruloplasmin 4. AAT 5. Thyroxine binding globulin
a. 1,3, 5
b. 2,3, 4 c. 1,3 d. 4,5
a 94. True of B-type natriuretic peptide test, except
a. New marker for AMI c. Heparinized plasma is the preferred specimen
b. Confirmation for d. Does not require fasting
congestive heart failure
495. For every 1°C increase in temperature above 37°C, p02 and pCO2 changed, respectively:
a. Decrease by 7% and increase by 3% C. Decrease by 3% and decrease by 7%
b. Increase by 7% and decrease by 3% d. Increase by 7% and increase by 7%
96. It is the earliest markerto rise in acute pancreatitis, and remains elevated for 48 hours:
a. AST b. Lipase c. ALP d. Amylase
97. This glycogen storage disease is characterized by deficiency of 1, 4 glucosidase:
a . Cori Forbes b. Pompe c. Mc Ardle d. Von Gierke
d 98. In QC ¢hart, a corrective action must be considered when such situation arise:
a. Six consecutive control values are drifting within +/-2s
b Six consecutive control values are above the mean but within +/-2s
c. Presence of one outlier in 20 days
d. One control value outside the area of t/-3s
will result to:
9 9 . Failure to transport heparinized blood on ice intended for blood gas and pH measurements,
a. pH increased, p02 increased, pC02 increased pH decreased, p02 decreased, pC02 increased
c.
b. pH decreased, p02 decreased, pCO2 decreased d. pH increased, p02 increased, pC02 decreased
100. Compensatory mechanism for respiratory acidosis:
c. Hypoventilation eens
a. Retention of bicarbonate
cuideys
b. Decreased reabsorption of bicarbonate d.Hyperventilation omuns etim Fr
instrument:
101. Source of error for an automated
1. Fibrin clot 3. Sample carry over
4. Inadequate sample volume
2. Air bubbles in sample cup
b. 1, 2 c. 1,2,3 d. 1, 2, 3, 4
a. I only
102. This type of automatic pipet functions like a bypodermic syringe and does not use disposable tips:
a. Positive displacement b. Air displacement c. Ostwald Folin d. Serological pipet
lower than in serum or plasma: bavi qlase pips t
103.Fasting glucose in whole blood is_ c. 25% d. 35%
a. 5% b. 15%
104. It is known as the floating beta ipoprotein, and it is elevated in dysbetalipoproteinemia:
a. Chylomicrons c. Lipoprotein (a)
miwr
b. B-VILDL Worvuld. Intermediate density lipoprotein
b 105. The following are systematic errors, except:
3. Improper calibration of the machine
1. Pipetting error
2. Temperature fluctuation 4. Contaminated reagent
b. 1,2 c.1,2,3 d. 1,2, 3,4
a. lonly