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Definition: Ophthalmia Neonatorum is an illness that causes acute inflammation of the eyes of a newborn during the
birth canal passage. Ophthalmia neonatorum is a conjunctivitis with discharge from the eyes that occurs
within the first 28 days of life.
Risk Factors/ Infections carried by the mother in the birth canal
Predisposing HIV-positive mothers
Factors: Infectious organisms are exposed to the newborn.
Exposure of the infant to infectious organisms
Premature rupture of membranes (PROM)
Inadequacy of postnatal ocular prophylaxis
Exposure to silver nitrate
Ocular trauma during delivery
Mechanical ventilation
Prematurity
Poor prenatal care
Poor hygienic delivery conditions
Signs and Lids
Symptoms: -oedema (may impede examination of ocular surfaces)
Conjunctival features
-mucopurulent conjunctivitis – discharge may be profuse in C. trachomatis infection. Danger of
infection of clinician when prising open lids
-NB: in neonatal C. trachomatis infection there are no follicles as in adults, because of the neonate’s
lack of lymphoid tissue
-conjunctival oedema (‘chemosis’)
-conjunctival membrane in severe cases
Corneal features
-cornea can be involved, especially in N. gonorrhoeae infection. This organism can pass through
intact corneal epithelium. Perforation may result
-signs usually bilateral; may be asymmetrical
(Usually described by mother):
-redness
-discharge (may be profuse in gonococcal infection)
-swelling of lids (may be severe)
-symptoms usually bilateral
Management: Medical Management:
Medical & Topical erythromycin ointment can be used as a supplementary treatment.
Surgical - This infection is treated for 14 days with oral erythromycin (50 mg/kg/d divided qid).
Monitoring
- Observation on bacterial infection complication, chemical conjunctivitis normally disappears in 24-36
hours.
In gonococcal conjunctivitis, normal saline irrigation helps to remove mucopurulent debris from the
lids and conjunctiva.
Nursing Nurses should examine blood samples obtained from heel sticks, as well as vitamin K and
Interventions: prophylaxis for ophthalmia neonatorum, as practices that should be evaluated in order to improve
evidence-based treatment of babies on their first day of life.
Practitioners should be aware of their limitations and, if necessary, seek additional counsel or send
the patient to another provider.
GRADE: The strength of the suggestion and the level of evidence are always related to the
statement(s) immediately above.
Educate the mother about her child's health and at the same time offer advice.
Encourage them to come back in three days for a follow-up, or sooner if necessary.
Reference/s: Bondi, S. (2019, August 14). Ophthalmia neonatorum Bondi. Share and Discover Knowledge on
SlideShare. https://www.slideshare.net/sashabondi/ophthalmia-neonatorum-bondi
Ophthalmia neonatorum. (n.d.). wikidoc. Retrieved April 19, 2022,
from https://www.wikidoc.org/index.php/Ophthalmia_neonatorum
Tesini, B. L. (2020, July 13). Neonatal conjunctivitis - Pediatrics - MSD manual professional edition. MSD
Manual Professional Edition. https://www.msdmanuals.com/professional/pediatrics/infections-in-
neonates/neonatal-conjunctivitis
Mayo Clinic - Mayo Clinic. (2020, February 13). HIV/AIDS - Diagnosis and treatment -
Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/hiv-aids/diagnosis-
treatment/drc-20373531
Neonatal abstinence syndrome (NAS). Home. (n.d.). Retrieved April 19, 2022, from
https://www.marchofdimes.org/complications/neonatal-abstinence-syndrome-(nas).aspx
Conditio Infant with fetal alcohol exposure
n:
Definitio Babies born to mothers who consumed alcohol while pregnant may have
n: birth abnormalities and developmental problems. Fetal alcohol spectrum
disorders (FASDs) are a collection of abnormalities that can occur when
newborns are exposed to alcohol. A wide range of physical, behavioral,
and learning issues are among them.
Risk Any drinking during pregnancy raises the chance of fetal alcohol
Factors/ syndrome, but the risk to the fetus is greatest if the pregnant woman
Predisp drinks in the second part of her first trimester.
osing
Factors:
Signs The severity of this disease differs. As a result, this disorder may arise in a
and variety of manners, including physical defects, intellectual or cognitive
Sympto deficits, and difficulties functioning and coping with daily life.
ms:
Physical defects:
Distinctive facial features, including small eyes, an exceptionally thin
upper lip, a short, upturned nose, and a smooth skin surface between
the nose and upper lip
Deformities of joints, limbs and fingers
Slow physical growth before and after birth
Vision difficulties or hearing problems
Small head circumference and brain size