Chemical Process Safety

Assignment Solution
Week 2
1. Substance that can produce poisonous or deadly effect in the body and are produced naturally
are termed as
a. Toxics
b. Toxins
c. Toxicants
d. All are same
2. Statement 1: Two different chemicals with same degree of toxicity can possess different
degrees of hazard.
Statement 2: The chemicals having properties to show warning symptoms on exposure may
present a lesser degree of hazard.
Choose the correct option
a. Statement 1 is true, Statement 2 is true
b. Statement 1 is true, Statement 2 is false
c. Statement 1 is false, Statement 2 is true
d. Statement 1 is false, Statement 2 is false
3. There are four routes of exposure to toxins. Choose them from the options given below
a. Injection
b. Ingestion
c. Exhalation
d. Inhalation
e. Digestion
f. Skin exposure
g. Cancer
h. Congestion
4. The typical order of effectiveness (reaction) of toxins in body from the route of exposure is
a. intravenous > inhale > intraperitoneal > intramuscular > ingest > topical
b. inhale > intraperitoneal > intravenous > intramuscular > ingest > topical
c. intraperitoneal > intravenous > inhale > intramuscular > ingest > topical
d. inhale > intravenous > intramuscular > intraperitoneal > ingest > topical
e. inhale > intravenous > intramuscular > ingest > intraperitoneal > topical
5. Statement 1: Self-poisoning with agricultural pesticides represents a major hidden public
health problem accounting for approximately one-third of all suicides worldwide.
Statement 2: The World Health Organization estimates that 300,000 people dies from self-
harm each year in the Asia-Pacific region alone.
Choose the correct option
a. Statement 1 is true, Statement 2 is true
b. Statement 1 is true, Statement 2 is false
c. Statement 1 is false, Statement 2 is true
 d. Statement 1 is false, Statement 2 is false
6. For orally administered dose, the toxic load (L) will be ________, the dose swallowed (d).
In the case of toxic gas being inhaled, then toxic load (L) will be the function of
concentration(c) and time (t), as __________.
Choose the correct answers in sequence from the option below.
a. L = d; L = c/t
b. L = 1/d; L = c/t
c. L = d; L = c.t
d. L = d; L = ctm, where m < 1 in case of acute poisoning
e. L = d; L = ctm, where m > 1 in case of acute poisoning
7. As per the One-compartment model in toxico-kinetic modeling of chemical exposure, the half-
life (t0.5) of the chemical if step response is administered, is given as _____.
Where, C0 is the initial concentration, X is the dose of chemical in body at time (t), K e is the
elimination constant.
a. T0.5 = C0/ 2Ke
b. T0.5 = 1/ C0 Ke
c. T0.5 = 0.693/Ke
d. T0.5 = Ke/ C0
8. The toxicants named “Teratogen” cause
a. Reversible effect to the body
b. Irreversible effect to the body
c. Either reversible or Irreversible effect to the body
d. All of the above
9. A person under depression took overdose of sleeping pills to end his life. This kind of
poisoning comes under the category of
a. Deliberate poisoning
b. Accidental Poisoning
c. Acute poisoning
d. Chronic poisoning
10. The amount (dose) of a chemical which produces death in 50% of a population of test
animals to which it is administered by any of a variety of methods is termed as
a. Effective dose
b. Toxic dose
c. Lethal dose
d. None