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Educators Notes

Dr Arpit Agarwal
Pharma Capsule 11-
Anti-Adrenergic Drugs
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Educators Notes

1. All are non-selective beta blockers with no action on any other receptor
Except
(a) Propranolol
(b) Timolol
(c) Sotalol
(d) Carvedilol
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Educators Notes

2. All are cardioselective beta blockers EXCEPT:

(a) Atenolol
(b) Esmolol
(c) Bisoprolol
(d) Propranolol
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Educators Notes

3. Properties making cardioselective beta-blockers desirable are all except

(a) Less bronchoconstriction
(b) Less adverse effect on lipid profile
(c) Less bradycardia
(d) Safer in Raynaud's disease patients
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Educators Notes

4. β-blocker to be avoided in glaucoma?

A. Propranolol
B. Carvedilol
C. Labetalol
D. All the above
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Educators Notes

5. In a patient with hypertension, propranolol was given. It controlled BP but

reduced resting HR to 50/min. Which B-blockers used in this patient as a
substitute which DOES NOT cause bradycardia
A. Pindolol
B. Esmolol
C. Bisoprolol
D. Atenolol
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Educators Notes

6. All β-blocker are safe in renal failure except

A. Sotalol
B. Betaxolol
C. Celiprolol
D. Propranolol
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Educators Notes

7. Which beta blockers can high incidence of CNS side effects like
nightmares?
A. Sotalol
B. Propranolol
C. Nadolol
D. Betaxolol
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8. Which of the following drug is a third generation beta-blocker?

(a) Propranolol
(b) Timolol
(c) Nadolol
(d) Nebivolol
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9. Combined alpha and beta blockers are all except

(a) Labetalol
(b) Carvedilol
(c) Celiprolol
(d) Bucindolol
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Educators Notes

10. Which of the following beta blockers increases HDL Cholesterol

(a) Labetalol
(b) Carvedilol
(c) Celiprolol
(d) Bucindolol
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Educators Notes

11. True about Esmolol are all except

A. It is a cardio-selective β-blocker devoid of partial agonistic action
B. Short elimination half-life of Esmolol is due to rapid metabolism in liver
C. It has no intrinsic sympathomimetic activity
D. It is avoided in LV decompensation
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12. All are contraindication of beta blockers except:

(a) Asthma
(b) Heart block
(c) Acute CHF
(d) Variant angina
(e) Hypertension
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Educators Notes

13 . Beta blockers are indicated for all EXCEPT

a. Hypothyroidism
b. Alcohol withdrawal
c. Portal hypertension
d. Performance anxiety
e. Hypertrophic subaortic cardiomyopathy
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Educators Notes

14. All can be used in beta-blocker overdose except?

(a) Atropine
(b) Nor-epinephrine
(c) Glucagon
(d) Calcium chloride
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Educators Notes

15. Which effects of adrenaline would be blocked by phentolamine but NOT by

propranolol?
(a) Cardiac stimulation
(b) Relaxation of bronchial smooth muscle
(c) Relaxation of the uterus
(d) Contraction of the radial smooth muscle in the iris
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Educators Notes

16. Ideal drug for preoperative preparation for pheochromocytoma is:

(a) Atenolol
(b) Phenoxybenzamine
(c) Reserpine
(d) Clonidine
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17. A patient of pheochromocytoma presents with chest pain, headache & BP

220/160 mm. Her urine metanephrine & VMA levels are high but normetanephrine
level is normal. The doctor gives her IV phentolamine. Within 10 min, she goes in
shock. What explains this response to phentolamine?
(a) Escape of the autonomic nervous system control over BP
(b) Metastasis of tumor to the vasomotor centre in medulla
(c) Patient's tumor secreting almost pure adrenaline and no noradrenaline
(d) Overdose of phentolamine
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Educators Notes

18. Vasomotor reversal of Dale is due to:

(a) α blocker
(b) β -blocker
(c) α and β -blocker
(d) None
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Educators Notes

19.Which alpha-blocker drug is used for BPH without producing significant

hypotension?
(a) Doxazosin
(b) Phentolamine
(c) Tamsulosin
(d) Terazosin
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Educators Notes

20.Which alpha-blocker used for BPH causes apoptosis in prostate smooth

muscles?
(a) Prazosin
(b) Phentolamine
(c) Tamsulosin
(d) Terazosin