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    This document discusses the risk factors and pathophysiology of chronic lymphocytic leukemia (CLL). It lists non-modifiable risk factors like age, gender, family history, and genetic factors. Modifiable risk factors include chemical, radiation, and weakened immune system exposure. The pathophysiology begins with the creation of hemocytoblasts in the bone marrow which then create lymphoid stem cells and lymphoblasts. The lymphoid stem cells normally create B and T lymphocytes, but in CLL the B lymphocytes fail to undergo apoptosis and accumulate in massive amounts in the bloodstream.

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    PATHO A

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    This document discusses the risk factors and pathophysiology of chronic lymphocytic leukemia (CLL). It lists non-modifiable risk factors like age, gender, family history, and genetic factors. Modifiable risk factors include chemical, radiation, and weakened immune system exposure. The pathophysiology begins with the creation of hemocytoblasts in the bone marrow which then create lymphoid stem cells and lymphoblasts. The lymphoid stem cells normally create B and T lymphocytes, but in CLL the B lymphocytes fail to undergo apoptosis and accumulate in massive amounts in the bloodstream.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    3 views1 page

    Patho A

    Uploaded by

    markanthony3903
    This document discusses the risk factors and pathophysiology of chronic lymphocytic leukemia (CLL). It lists non-modifiable risk factors like age, gender, family history, and genetic factors. Modifiable risk factors include chemical, radiation, and weakened immune system exposure. The pathophysiology begins with the creation of hemocytoblasts in the bone marrow which then create lymphoid stem cells and lymphoblasts. The lymphoid stem cells normally create B and T lymphocytes, but in CLL the B lymphocytes fail to undergo apoptosis and accumulate in massive amounts in the bloodstream.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    PLT COLLEGE INC.

    Bayombong, Nueva Vizcaya

    School of Health and Sciences College of Nursing

    VIII. PATHOPHYSIOLOGY

    A. HEMATOPOESIS
    CHRONIC LYMPHOCYTIC LEUKEMIA
    PATHWAY

    RISK FACTORS

    MODIFIABLE FACTORS
     CHEMICAL EXPOSURE
    NON-MODIFIABLE FACTORS (BENZENE, HERBICIDES,
     AGE (50 ABOVE) PESTICIDES)
     GENDER (MEN)  RADIATION EXPOSURE
     FAMILY HISTORY  WEAKENED IMMUNE
     GENETIC FACTORS SYSTEM
     MOSTLY UNKNOWN  AUTOIMMUNE DISORDERS
     GENETIC FACTORS

    PATIENT A.E.B

    BONE MARROW BLOODSTREAM


    (IT STARTS HERE)

    HEMOCYTOBLAST(S)
    (CREATED IN THE BONE MARROW)

    LYMPHOID STEM CELL(S)


    (CREATED BY HEMOCYTOBLASTS)

    WITHIN
    LYMPHOBLAST(S)
    (CREATED BY THE LYMPHOID STEM CELL)

    B LYMPHOCYTES
    PROLYMPHOCYTE(S) FAIL TO
    (CREATED BY LYMPHOBLASTS) UNDERGO
    APOPTISIS

    MASSIVE
    AMMOUNTS OF
    MATURE OR SMALL
    T LYMPHOCYTES B LYMPHOCYTES APPEARING
    (T CELLS) (B CELLS) LYMPHOCYTES

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