1)Ampk causes;

1 decrease biosynthesis mitochondria I E

¢
v.
2- increase fa synthesis
3-increase glucose uptake to myocradiocys
4-decrease glucose uptake to skeletal muscle

2)Choose 1 true vit D false:

1-in skin it’s converted with cytochrome p450
2-synthetic form of d 3 is given to treat psoriasis
3-it’s proliferating effect
4-recepros are nuclear
5-it’s .....

3)Choose the correct for lipoproteins in general

✓
1-vldl is formed only in liver
2-uptake by ldl related receptor by extrahepatic tissues 3

÷
3-hdl is app e donor
4-apo b

Sources of cholesterol

4)Choose aminoacids transported by lat 1

A-lys
B-asp U
C-leu
D-phe

5)
s
A triacylglycerol increase
B-ldl receptors decrease
C-cholesterol decrease ✓
D - glucose decrease

6)Possible ways to decrease cholesterol in blood :

A-inhibit Srb1 receptors
6
B-inhibit abca1 Cassatt.....
C-diet approch
E-increase reverse chelesterol pathway

PLD

7)The following enzyme use lol except:

01-serine hydratase
2- cysthionine synthase ✓
3-ketoglut/sap transaminase ✓ ①
histidine 4-histamine decarboxylase
5-sam decarboxylase (pyruvyl )
✗
9)Thfr polymorphism
A fad i
B is mostly common in humans
C- it’s dissociation is faster then the wild type ✓
D

8)Severe folate deficency; may cause

1-anemia
2- decrease in UTP and as a result decrease uranyl incorporating in dna
3-
4

9] phe degradation
1-is reversable
2- it’s reaction the cofactors is a vitamin
3_ dioxygena open the ring
4-

Source of ammonia
A-serine hydratase
B-arginase
C-arg/alphaketa transaminase
D-hydroxyl are....

11)hi/ha can be cased by dysfunctional of:

A-cps1
B-glud 1 12
C-N acyl glu synthase
D-otc 1
E-

Citrulinamia cased by:

A). OTC deficiency
B)may due to asp/glut transport citrin
C)cps1 deficiency
D) ‫ לא היה אופציה על‬succinyloargi synthase
E)

13)in type 1 insulin resistance choose false

A) is born with insulin resistance
B- glucagon is in major effect
C)high lvl of fa in blood
D)glucose in excess in blood
E)fa synthesis decreased

14Choose corrects: false

A- aspirin inhibit lipoxygenase
B-Thromboxanes formed in patelets (aggregation of
platelets,contraction of smooth muscle)
c-PGI2 in the endothelial cells (inhibition of aggregation of
platelets, inhibition of contraction of smooth muscle)
D-TX3 is a weaker aggregator than TX2,
E-Initiation of sleep (PGD 2

15)phe/keto transaminase
A)reversable
B-does not eliminate amino from pool
C-
6
D-

Cps1-
A found mostly in perivenule liver
B- when blocked accumulates ——- protocol acid in cytosine
C- inhibited by duty / ut-
D-allosteric activatore n ac glu
17

Purine degradation enzymes

If
Adenosine deaminase
Amp deaminase
Cantina oxidase
Pnp

LESCH-NYHAN SYNDROME → PDGTP

GOUT

19

Ls
:
Are naturally produced none proteogenic a:
A- alpha aminoadapate
B-citrulline
C- ornit
D-aspartate

na

fo b
I al
 essential
nonessential
is 1Both
Nuc Ike
I
said 70
s