Weekly Lesson Plan-Week 13

Term 2
Teacher: Dare Falodun Subject: Biology Class Year 12 Date 01/04/2023

Topic Learning Objectives Student Activity Teacher Activity Resources

Nucleic acids At the end of the lesson Learners research Describe the structure of nucleotides, including the Cambridge
and protein students should be able the action of phosphorylated nucleotide ATP. International
synthesis to: various State that the bases adenine and guanine are purines with a AS & A Level
Lesson 1  describe the chemotherapy double ring structure, and that the bases cytosine, thymine and Biology
structures of drugs, which uracil are pyrimidines with a single ring. Coursebook
nucleotides and prevent DNA Describe the structure of a DNA molecule as a double helix. by Mary
nucleic acids replication and Describe the structure of an RNA molecule, using the example Jones,
slow down cell of messenger RNA. Richard
 describe the semi-
division. Fosbery,
conservative
Describe the semi-conservative replication of DNA during the Dennis
replication of DNA
S phase of the cell cycle, including: Taylor,
 the roles of DNA polymerase and DNA ligase Jennifer
the differences between leading strand and lagging strand Gregory
replication as a consequence of DNA polymerase adding
nucleotides only in a 5′ to 3′ direction.

Nucleic acids Learners State that a polypeptide is coded for by a gene and that a gene is
 explain how the
and protein construct an a sequence of nucleotides that forms part of a DNA molecule.
sequence of
synthesis analogy for
nucleotides in DNA
Lesson 2 protein synthesis. Describe the principle of the universal genetic code in which
codes for the
different triplets of DNA bases either code for specific amino
sequence of amino
acids or for start and stop signals.
acids in a
polypeptide
  explain the roles of Describe how the information in DNA is used during
DNA and RNA in Learners engage transcription and translation to construct polypeptides, including
Nucleic acids transcription and with a case study the roles of: RNA polymerase, messenger RNA, codons, transfer
and protein translation to analyse the RNA, anticodons, ribosomes.
synthesis  discuss the effect of sequence of DNA
Lesson 3 gene mutation from the HbA State that the strand of a DNA molecule that is used in
(normal) allele of transcription is called the transcribed or template strand and that
the beta-globin the other strand is called the non-transcribed strand.
gene, and then the State that a gene mutation is a change in the sequence of base
mutant HbS allele. pairs in a DNA molecule that may result in an altered
Host a discussion polypeptide.
to describe the
difference Explain that a gene mutation is a result of substitution or
between these deletion or insertion of nucleotides in DNA and outline how
molecules, and each of these types of mutation may affect the polypeptide
suggest how this produced.
may have
happened.

Assessment of learning Teachers facilitate and answer students’ questions

Learners work on
Nucleic acids exam-style
and protein questions on page
synthesis 123 - 125
Lesson 4

Reflection
What went well?

What could be
improved?