IMPLEMENTING

MANUFACTURING
EXECUTION SYSTEMS:
FIVE KEYS TO SUCCESS
(PHARMACEUTICAL INDUSTRIES)

MUHAMAD SAIDI BIN MAT ALI

Powerpoint Templates
GB 100281

Page 1

Introduction
ERP and APS can greatly
strengthen companys ability to
compete, but these system do not
impact the basic manufacturing
process: production of quality
pharmaceuticals.
MES can fill the execution gap by
deliver information that enables
the optimization of production
activities from order launch to
finished goods.
Powerpoint Templates

Page 2

Case Example: Impact Of MES

Implementation at Major
Pharmaceutical Company
Reduced manufacturing cycle
time by 30%
Reduced WIP cycle time by 30%
Reduced manual data entry time
by over 40%
Reduced lead time by over 20%
Reduced risk of noncompliance
due to product deviations or
faulty/missing records
Powerpoint Templates

Page 3

Five Keys to MES Success

1. Implement where
opportunity is greatest
2. Use an MES as a vehicle
for process
improvement
3. Link MES and APS/ERP
systems strategically
4. Coordinate clinical and
commercial production
5. Select the right
implementation partner
Powerpoint Templates

Page 4

Implement Where
Opportunity is Greatest
Inventory improvement,
FDA compliance and risk
reduction,
Rapid turnover of production
lines.

Powerpoint Templates

Page 5

Use an MES as a Vehicle for

Process Improvement
Consistent operation across
operators,
Standardize processes
across multiple plants with
diverse operation and
procedural dissimilarities,
Staff utilization advantages.
Powerpoint Templates

Page 6

Link MES and APS/ERP

Systems Strategically
Integration between the
systems that control finance,
supply chain and the
manufacturing processes,
Allow automatic scaling and
sequencing of recipes and
specification,
Linkage of financial and
production greatly improve
strategic understanding of
Powerpoint Templates
business operations

Page 7

Coordinate Clinical and

Commercial Production
Accelerate the process of scaling
up production recipes,
Reduce time to market,
Allows clinical production
procedure to be captured
modification or scale up can be
performed easily.
Powerpoint Templates

Page 8

Select the Right

Implementation Partner
In-depth understanding of
the strategic and business
process framework,
Extensive experience in
IT-enabling manufacturing
process redesign,
Skills to integrate MES
with ERP, APS and process
Powerpoint Templates
control systems.

Page 9

Conclusion
MES must link to other critical
systems in the enterprise
Seek partner with in-depth
understanding of the strategic
and business process
framework within which the
MES operate
MES can increase the strategic
agility and provide significant
cost savings and regulatory
advantages, but Powerpoint Templates
implementation can be

Page 10

Thank you..

Powerpoint Templates

Page 11