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Essentials of Anatomy and Physiology

Fifth edition
Seeley, Stephens and Tate

Chapter 6: Skeletal System,


Bones and Joints

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The Skeletal System

 Components of the skeletal system


 Bones (skeleton)
 Joints
 Cartilages
 Ligaments

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The Skeletal System

 Two subdivisions
 Axial skeleton
 Appendicular
skeleton

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Functions of Bones

 Support of the body


 Protection of soft organs
 Movement due to attached skeletal
muscles: “passive”
 Storage of minerals and fats
 Blood cell formation
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Bones of the Human Body
 The skeleton has ~206 bones
 Two basic types of bone tissue
 Compact bone
 Dense
 Spongy bone
 Small needle-like
pieces of bone
Figure 5.2b

 Many open spaces


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Classification of Bones

 Long bones
 Typically longer than wide
 Have a shaft with heads at both ends
 Contain mostly compact bone
• Examples: Femur, humerus

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Classification of Bones

 Short bones
 Generally cube-shape
 Contain mostly spongy bone
 Examples: Carpals, tarsals

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Classification of Bones on the
Basis of Shape

Figure 5.1

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Classification of Bones

 Flat bones
 Thin and flattened
 Usually curved
 Thin layers of compact bone around a layer
of spongy bone
 Examples: Skull, ribs, sternum

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Classification of Bones

 Irregular bones
 Irregular shape
 Do not fit into other bone classification
categories
 Example: Vertebrae and hip

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Classification of Bones on the
Basis of Shape

Figure 5.1

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Gross Anatomy of a Long Bone

 Diaphysis
 Shaft
 Made of compact bone
 Epiphysis
 Expanded ends of long
bones
 Covered with dense bone
 Internal structure is spongy
bone
Figure 5.2a

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Structures of a Long Bone

 Periosteum
 Outside covering of
the diaphysis
 Fibrous connective
tissue membrane
 Arteries
 Supply bone cells
with nutrients

Figure 5.2c

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Structures of a Long Bone

 Articular cartilage
 Covers surface of
epiphyses
 Hyaline cartilage
 Decreases friction
at joint surfaces

Figure 5.2a

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Structures of a Long Bone

 Medullary cavity
 Cavity in shaft
 Contains yellow
marrow in adults
 Contains red marrow
in infants

Figure 5.2a

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Microscopic Anatomy of Bone

 Osteon (Haversian System)


 A subunit of compact bone
 Central (Haversian) canal
 Opening in the center of an osteon
 Carries blood vessels and nerves

Slide
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5.10a
Microscopic Anatomy of Bone

Figure 5.3

Slide
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5.10b
Microscopic Anatomy of Bone
 Lacuna(e)
 Cavities containing
osteocytes
 Arranged in
concentric rings
 Lamella(e)
 Rings of compact
bone
 Lacunae lie between
rings Figure 5.3

Slide
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5.11a
Microscopic Anatomy of Bone

 Canaliculi (-us)
 Tiny canals
 Radiate from the
central canal to
lacunae
 Form a transport
system
Figure 5.3

Slide
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5.11b
Types of Bone Cells
 Osteocytes
 Mature bone cells (bone maintenance)
 Osteoblasts
 Bone-forming cells
 Osteoclasts
 Bone-destroying cells
 Break down bone matrix for remodeling and
release of calcium

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Bone Growth: Endochondral

1) A cartilage model is produced by


chondrocytes
It is surrounded by perichondrium, a membrane

2) A bone “collar” is produced by


osteocytes
The perichondrium of the diaphysis is now termed
periosteum

Slide
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5.13a
Long Bone Formation and Growth

Figure 5.4a

Slide
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5.14a
Bone Growth: Endochondral

3) Chondrocytes hypertrophy (enlarge) and


cartilage is calcified
4) A primary ossification center forms
 Blood vessels and osteoblasts invade the
calcified cartilage
 Osteoblasts lay down bone matrix
 Trabeculae are formed
Slide
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5.13a
Long Bone Formation and Growth

Figure 5.4a

Slide
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5.14a
Bone Growth: Endochondral

5) Around the time of birth, secondary


ossification centers form in the epiphyses
 Bone formation is incomplete at birth
 The skeleton is not complete until the late
teens (females) or early twenties (males)

Slide
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5.13a
Long Bone Formation and Growth

Figure 5.4a

Slide
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5.14a
Bone Growth: Endochondral

 Epiphyseal plates allow for growth of


long bone during childhood
 New cartilage is continuously formed
 Older cartilage becomes ossified
 Cartilage is broken down
 Bone replaces cartilage

Slide
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5.13a
Long Bone Formation and Growth

Figure 5.4b

Slide
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5.14b
Bone Growth: Endochondral

 Bones are remodeled and lengthened


until growth stops
 Bones change shape (how?? DNA!!!)
 Bones grow in width (osteoblasts)
 Bones are remodeled by osteoclasts

Slide
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5.13b
Long Bone Formation and Growth

Figure 5.4a

Slide
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5.14a
Changes in the Human Skeleton
 In embryos, the skeleton is primarily hyaline
cartilage
 During development, much of this cartilage
is replaced by bone
 Cartilage remains in:
 Anterior portion of the nose
 Parts of ribs
 Joints
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.12
Bone Growth: Intramembranous
Fig. 6.4

•“Between
membranes”
•Compact Bone
•Spongy Bone
•Trabeculae
•Cross-
section of a
trabecula

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.12
Bone Formation: Intramembranous
 Membranous
bones are Fig. 6.5a

incomplete at birth
 Fontanelles: regions of
the skull that remain
as membranes
 “Little fountains”
 Bone formation
complete by age ~2

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Bone Fractures
 A break in a bone
 Types of bone fractures
 Closed (simple) fracture –does not penetrate
the skin
 Open (compound) fracture – broken bone
penetrates through the skin
 Bone fractures are treated by reduction
and immobilization

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Common Types of Fractures
Fig. 6B

Table 5.2

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Repair of Bone Fractures
 Hematoma (blood clot) is formed
 Break is splinted by fibrocartilage
forms a callus (chondroblasts, other
cells, and vessels)
 Callus is replaced by a bone
(osteoblasts)
 Bony callus is remodeled (osteoclasts)
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Repair of Bone Fractures
Fig. 6.8

 Fracture Repair
 Hematoma
formation (A)
 Callus formation
(B)
 Bone replacement A B C D
(C )
 Bone remodeling
(D)
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Bone Fractures: Osteoporosis
 Most common in post-menopausal women
 Also occurs in males
 Due to decrease in estrogen levels
 Estrogen receptors on osseous tissue affect
calcium deposition
 Bone becomes porous, brittle
 Weight-bearing exercise, calcium
supplements, estrogen will help prevent
osteoporosis
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.16

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