Professional Documents
Culture Documents
Introduction .1
Anemia .2
Iron deficiency anemia .3
G6PD deficiency .4
.A plastic Anemia .5
ITP.5
Blood
Blood is the fluid of life
:Blood is composed of
Plasma ◦
RBC ◦
WBC ◦
Platelets ◦
:Plasma consists of
.water 90% ◦
Transmitted as a sex-linked -
recessive
Mediterranean and middle eastern -
groups have high frequencies of
G6OD deficiency
Clinically
Usually no evidence of hemolysis is apparent
until 48-96 hours after the patient has
ingested a substance which has oxidant
properties
Antipyretic,Sulfonamide, Anti malarial, or fava(
producing an acute and severe ) beans
hemolytic syndrome called FAVISM, Hb level
become very low, presence of
hemoglobinemia/-uria, mild jaundice,
splenomegally and increased reticulocyte count
G6PD deficiency is an
important cause of
neonatal hemolysis and
neonatal jaundice
Fatigue
Pallor
Low back pain
Shortness of breath
Tachycardia
Jaundice
Dark urine (Cola color)
Spleenomegaly
Diagnosis
Low G6PD activity in red blood
cells
Treatment
When hemolysis has occurred =>
Red blood cell transfusion
Prevention
Avoiding ingestion of fava
beans
or oxidant substances
Isan acquired hemorrhagic disorder that is
characterized by excessive destruction of
platelets (thrombocytopenia) and purpura
(discoloration caused by petetchia beneath
the skin)
Causes: Unknown, Autoimmune and after
.upper respiratory tract infection
:Diagnosis
Clinical symptoms
Platelet count < 20.000 mm3, so
tests that
relate to bleeding time are abnormal
:Treatment
Supportive, Activity is restricted
Corticosteroids and Gamma globulin
.increase platelet count
.Packed RBC
Spleenectomy