Professional Documents
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CONCEPT
MAPPING
MAPPING
GROUP 1
MEMBERS:
ACOB, Maurelle Joyce BITUIN, Aira Jane
ALFON, Rhys Abegail CADUTDUT, Jella Rose
ANAVISO, Jeremy Kent CAGA, Prince Cedrick
ANDONG, Geron CONSTANTINO, Rianne
BARRIDO, LJ DACARA, Shiela Rose
BERNAL, Danica DAG-AY, Saira
BESANA, Retchel Ann
CASE
CASE
SCENARIO
SCENARIO
PUERPERAL MASTITIS
CASE SCENARIO OF PATIENT WITH PUERPERAL MASTITIS
A 26-year-old first time mother who was
breastfeeding her seventh-month-old baby boy
seek consultation to OPD with a three-day
Clinical diagnosis:
history of headache, fever, general malaise on
Puerperal Mastitis
the day of admission. On further questioning,
she also reported increasing pain in her left
Laboratory results:
breast over the last 24 hours.
• Blood count: Presence of left shift with 80 percent
neutrophils (total white blood cell count of 9.8×109
Admission findings:
cells/L)
(+) tender left breast
• Cerebral computed Tomography (CT): Normal
(+) erythematous left breast
• Magnetic Resonance Imaging (MRI) scan: Normal
(+) indurated in the right lower lateral quadrant
• Blood culture: Normal
in left breast
(-) area of abscess
Medication orders:
(+) tender left axillary adenopathy
• Nafcillin 1g q 6hrs IV
(+) restlessness and irritable
• Paracetamol 300mg q 4hrs IV
(+) headache, fever, and general malaise
Post admission orders:
Vital signs:
Dicloxacillin 500mg q 6hrs for 10 days PO
Temperature: 38.5C
THE CONCEPT
MAPPING FOR
PUERPERAL MASTITIS
ETIOLOGY
&
DIAGRAM
ETIOLOGY
NON-MODIFIABLE RISK Common causative agent: Staphylococcus MODIFIABLE RISK FACTORS
FACTORS aureus followed by coagulase-negative
• Headache
• SEX: FEMALE
Staphylococci. • Fever
• AGE: 26 YEAR OLD • General malaise
• First time mother • Pain in the left breast
PATHOPHYSIOLOGY
THEORITICAL:
Mastitis is an inflammation of breast tissue that sometimes involves an infection. The inflammation results in breast pain, swelling, warmth and redness. You
might also have fever and chills. It is most commonly affects women who are breast-feeding (lactation mastitis).
Breast infection can be a pathologically based negative influence on breast feeding. There are basically five types of lactational mastitis: subclinical mastitis,
acute puerperal mastitis (cellulitis and adenitis), suppurative mastitis, mammary infection with uncommon organisms, and virus infection in mammary
neoplasms. Puerperal mastitis is the inflammation of the breast in connection with pregnancy, breastfeeding or weaning. Since one of the most prominent
symptoms is tension and engorgement of the breast, it is thought to be caused by blocked milk ducts or milk excess. Puerperal mastitis does not present
until several weeks or months after delivery and may go unrecognized by health care providers if women do not seek medical treatment. Puerperal mastitis
is reported to occur in 2% to 24% of breastfeeding women from several weeks to up to 1 year after delivery in women who continue to breastfeed.
The source of infection is the nursing infants nose and throat; the organisms being Staphylococcus aureus and Streptococcus spp. Due to a breach in the
nipple-areola complex, such as a cracked nipple, there is retrograde dissemination of these normal commensals. This is further favored by stasis of milk as
stagnant milk is an excellent medium for bacterial growth. Staphylococcus aureus infections tend to be more invasive and localized leading to earlier abscess
formation; while Streptococcus infections tend to present as diffuse mastitis with focal abscess formation in advanced stages.
CLIENT-BASED:
In this case scenario, the patient experienced symptoms of puerperal mastitis as related to an increasing pain in her left breast over the last 24 hours and
signs due to headache, fever, general malaise on the day of her admission. In this situation the client experience slightly tender left axillary adenopathy, no
area of abscess although purulent milky secretions expelled from left nipple with mild peri-areolar pressure and secretions were cultured indicative of
puerperal mastitis.
The laboratory results include normal blood count, except for the presence of left shift with 80 percent neutrophils of total white blood cell count of 9.8x109
cells/L. Cerebral computed tomography (CT) and magnetic resonance imaging (MRI) scans, blood cultures which results were all normal. Nafcillin was given
to treatment with intravenous, continue pumping her breast milk and Dicloxacillin through oral for 10-day course.
MEDICAL DIAGNOSIS
PUERPERAL MASTITIS
DIAGNOSTIC TEST
CLINICAL MEDICAL & SURGICAL Blood culture: Normal
MANIFESTATIONS MANAGEMENT Cerebral computed
Headache; fever; general Cerebral computed tomography (CT); tomography (CT): Normal
malaise; increasing pain Magnetic resonance imaging (MRI) Magnetic resonance
in her left breast over the scans; CBC blood cultures; imaging (MRI) scans:
last 24 hours intravenous initiated Nafcillin, 1g q 6h Normal
and Paracetamol 300mg q 4h
SIGNIFICANCE/PERTINENT FINDINGS
Blood count: Presence of left shift with 80% neutrophils
(total white blood cell count of 9.8×109 cells/L)
ANATOMY
&
PHYSIOLOGY
A N AT O M Y & P H Y S I O L O G Y
PAT H O P H Y S I O L O G Y
T H E O R I T I C A L PAT H O P H Y S I O L O G Y
PUERPERAL MASTITIS
STAPHYLOCOCCAL INFECTION
Inflammation
Poor attachment
Breast engorgement
Patient reported increasing pain in her left breast over the last 24 hours
There is a tender left breast that was erythematous and indurated in the right lower lateral quadrant
Blood count: presence of a left shift with 80 percent neutrophils (total white blood cell count of 9.8×109
cells/L).
PUERPERAL MASTITIS
DIAGNOSTIC
&
LABORATORY
DIAGNOSTIC TEST
Cerebral computed tomography M a g n e ti c r e s o n a n c e i m a g i n g ( M R I )
(CT): scans:
(+) left shift with 80% neutrophils There is a presence There is an inflammation or
WBC 5-10 x 10/l
9.8×109 cells/L of left shift infection
P H Y S I C A L E X A M I N AT I O N C L I N I C A L R E S U LT
• Restless
• Irritable
Three-day history of: • Febrile: 38.5C
• Headache • Tenderness in left breast that
• Fever
was erythematous and
• General malaise
indurated in the right lower
lateral quadrant
• Increasing pain in her left breast • No area of abscess although
over the last 24 hours purulent milky secretions
• Slightly tender left axillary
adenopathy
T R E AT M E N T
&
L A B O R AT O R Y
MEDICAL/SURGICAL MANAGEMENT
MEDICAL MANAGEMENT
SURGICAL MANAGEMENT
Not needed at the moment
DRUG STUDY
MEDICATION ACTION INDICATION CONTRAINDI- DRUG TO ADVERSE NURSING
CATION DRUG EFFECT CONSIDERATION
INTERACTION
GENERIC NAME PHARMACO- • Systemic • Hypertensive • Aminoglyco GI: • Before giving drug, ask
Nafcillin DYNAMICS infections to drug or sides • Nausea patient about allergic
Exerts caused by other • Cyclosporin • Vomiting reactions to penicillin.
BRAND NAME bactericidal susceptible penicillin e • Diarrhea
Nafcillin sodium activity via organisms • Patients with • Probenecid Hematologic: • Monitor WBC counts
inhibition of (methicillin- drug allergies • Rifampin • Transient twice weekly in
CLASSIFICATION bacterial cell wall sensitive especially to • Warfarin leukopenia patients receiving
Antibiotic synthesis by Staphylococcus cephalosporin • Neutropenia nafcillin for longer
binding one or aureus) s • Granulocyto than 2 weeks.
DOSAGE & more of the penia Neutropenia
FREQUENCY penicillin binding • Thrombocyt commonly occurs in
1g q 6h proteins (PBPs). openia the third week
Exerts bacterial Other:
ROUTE autolytic effect by • Hypersensiti • If urinalysis is
Intravenous (IV) inhibition of vity abnormal. Notify
certain PBPs reactions prescriber this may
related to the • Vein indicate drug-induced
activation of a irritation interstitial nephritis
bacterial • thrombophl
autolytic process. ebitis
PHARMACO-
KINETICS
PHARMACOKENETICS of N A F C I L L I N
Metabolized in PROTEIN-BOUNDED:
liver
70% to 90%
Undergoes METABOLISM
enterohepatic
circulation
Widely
distributed
DISTRIBUTION
PROTEIN-
90% to 95%
BOUNDED: 25%
metabolized METABOLISM
in liver Widely
distributed to
MOSTLY BODY
DISTRIBUTION
TISSUES
PUERPERAL MASTITIS
There is a sign and symptoms of Puerperal Mastitis seen in the patient during
physical examination and clinical result. Such as increasing pain, tenderness
and erythematous on her left breast. Also, the patient has a fever (38.5C).
CLINICAL INSTRUCTOR: