Gall Bladder- Microscopic

Anatomy
Dr. Naureen Ali
KIMS
 Gall Bladder
• IMPORTANT HISTOLOGICAL POINTS:
• The wall of the gall bladder consists of three
coats i.e. innermost mucosa, muscularis and
the serosa/adventitia.
• The mucosa consists of simple tall columnar
epithelium with basal oval nuclei and the
lamina propria comprising of loose connective
tissue. The mucosa thrown into numerous folds.
• The muscularis layer consists of interlacing
bundles of smooth muscles fibers.
• The serosa/adventitia is a thick layer of dense
connective tissue.
• (Note: The gall bladder does not have a layer
of mucularis mucosae or submucosa).
Appendix - Microscopic Anatomy

Dr. Naureen Ali

KIMS
 Appendix
IMPORTANT HISTOLOGICAL POINTS:  
• All the four layers i.e. innermost mucosa, submucosa,
muscularis externa and serosa are seen in the appendix.
• It has thick wall but relatively narrow lumen which is stellate
or irregular in outline.
• The intestinal villi are absent.
• The surface mucosa resembles that of the colon. The surface
mucosa is lined by the absorptive cells with few goblet cells.
The crypts of Lieberkühn are present and the mucosa of the
gland is lined by the columnar absorptive cells as well as the
goblet cells.
• The lamina propria is heavily infiltrated with the
lymphocytes and contains numerous lymphoid
nodules which may penetrate muscularis
mucosae to extend into the submucosa.
• The muscularis externa is thin but has a
complete outer longitudinal smooth muscle
layer which is not bundled into bands.
• The serosa forms outer most coat of the
appendix.