Acute Myeloid

Leukemia
(Case study)
Prepared by
Hevar Nyaz

Supervised by
Dr Othman Ali
TABLE OF CONTENTS

01. 02. 03.

ABOUT Acute Myeloid DIAGNOSIS Case presentation
Leukemia

04. 05. 06.

Lab tests Conclusion REFERENCES
01.
ABOUT Acute Myeloid
Leukemia
ABOUT Acute Myeloid
Leukemia

● Acute myeloid leukemia (AML) is a cancer of the

myeloid line of blood cells, characterized by the rapid
growth of abnormal cells that build up in the bone
marrow and blood and interfere with normal blood cell
production.
ABOUT Acute Myeloid Leukemia

How deadly it is ? It is most common Mortality rate

among
The five-year survival rate for only 24% of the patients survive
adults with AML Adults this type of cancer
(It is very deadly)
 DIAGNOSIS
bone marrow biopsy
a small sample of your bone marrow will be
taken to examine under a microscope.

Blood tests
Usually CBC

Genetic evaluation
P210
FLT3-ITD
P190
BCR–ABL
 Case
presentation
Patient
Patient Characteristics
• 53-year-old male, named Lele hamaxan
• Retired teacher
• Type I diabetic

Medical History
• Previous history of diabetes
• Type I diabetes
• history of anemia
Pateint

Heart rate and blood Temperature

pressure 87.4°F
72 bpm
110/67mmHg
Lab tests
Abdomen test
Due to fever, palpation of the abdomen revealed an enlarged
spleen and tenderness with homogenous texture.
 The diagnosis was based on
11,9%
The diagnosis of acute
myeloid leukemia was based
on flow cytometry peripheral
45,5% blood.
42,6%
TREATMENT
She received many drugs and supportive fluid in the ICU the blew chart shows drug the
dosage and the day of administration, as we speak, she is still receiving chemotherapy
 ABOUT THE
SYMPTOMS

● tiredness.
● breathlessness.
● a high temperature
● losing weight
● frequent infections (in this case it was
bacterial infection)
 THIS IS A TIMELINE

The diagnosis Present

She was diagnosied on She still receive

13/4/2021 treatment
 Conclusion
• The importance of genetic evaluation in diagnosis
of AML
REFERENCES

● Villela, L. and Bolaños-Meade, J. (2011) "Acute Myeloid Leukaemia", Drugs, 71(12), pp. 1537-1550. doi:
10.2165/11593060-000000000-00000.

● Vakiti, A. and Mewawalla, P. (2020) "Acute Myeloid Leukemia", StatPearls, p. Available at:
https://www.statpearls.com/ArticleLibrary/viewarticle/25443 (Accessed: 17 May 2021).

● Acute Myeloid Leukemia Review Articles | Scientific Journals (2021). Available at:
https://www.alliedacademies.org/scientific-journals/acute-myeloid-leukemia-review-articles-4026.html (Accessed: 17 May
2021).

● Short, N., Rytting, M. and Cortes, J. (2018) "Acute myeloid leukaemia", The Lancet, 392(10147), pp. 593-606. doi:
10.1016/s0140-6736(18)31041-9.

● Acute Myeloid Leukemia Review Articles | Peer Reviewed Articles (2021). Available at:
https://www.openaccessjournals.com/peer-reviewed-articles/acute-myeloid-leukemia-review-articles-19849.html
(Accessed: 17 May 2021).

● What Is Acute Myeloid Leukemia (AML)? | What Is AML? (2021). Available at: https://www.cancer.org/cancer/acute-
myeloid-leukemia/about/what-is-aml.html (Accessed: 17 May 2021).

● Topics, H. (2021) Acute Myeloid Leukemia | AML | MedlinePlus, Medlineplus.gov. Available at:
https://medlineplus.gov/acutemyeloidleukemia.html (Accessed: 17 May 2021).
THANKS!
any questions?

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