DRUG STUDY

STUDENTS NAME: CRISTINE ANNE A. DELA CRUZ YEAR & SECTION: BN3G GROUP 1 DRUG NAME DOSAGE/FREQUENCY/ ROUTE DOSAGE: 40g FREQUENCY: OD BRAND NAME: Losec (CAN) DRUG CLASSIFICATION: Antisecretory drug Proton pump inhibitor ROUTE: IVTT MECHANISM OF ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING CONSIDERATION

GENERIC NAME: Omeprazole

Gastric acid-pump inhibitor: Suppresses gastric acid secretion by specific inhibition of the hydrogenpotassium ATPase enzyme system at the secretory surface of the gastric parietal cells; blocks the final step of acid production.

Indicated for: Short-term treatment of activeduodenal ulcer; First-line therapy in treatment of heartburn or symptoms of gastroesophageal reflux disease (GERD); Short-term treatment of active benign gastric ulcer; GERD, severe erosive esophagitis, poorly responsive symptomatic GERD; Long-term therapy: Treatment of pathologic hypersecretory conditions (Zollinger-Ellison syndrome, multiple adenomas, systemic mastocytosis); Eradication of H. pylori with amoxicillin or metronidazole and clarithromycin;

Contraindicated with hypersensitivity to omeprazole or its components; Use cautiously with pregnancy, lactation.

CNS: Headache, dizziness, asthenia, vertigo, insomnia, apathy, anxiety, paresthesias, dream abnormalities Dermatologic: Rash, inflammation, urticaria, pruritus, alopecia, dry skin GI: Diarrhea, abdominal pain, nausea, vomiting, constipation, dry mouth, tongue atrophy Respiratory: URI symptoms, cough, epistaxis Other: Cancer in preclinical studies, back pain, fever

C: Antisecretory drug; Proton pump inhibitor H: IVTT E: decrease gastric acid secretion C: Take the drug before meals. Report severe headache, worsening of symptoms, fever, chills. K: Swallow the capsules whole; do not chew, open, or crush them.