Insulin Resistance

Hyperglycemia
Diabetes Type 2
Blood
Osmolality
Blood
viscosity
Blood sugar exceeds
renal threshold
Glucose cannot
enter cell
Gluconeogenesis
activation
Fluid shifting
from
intracellular to
extracellular
Intracellular
DHN
Thirst
Sensation
Polydipsia
Blood
Flow
Favors
bacterial
growth
Tissue
Perfusion
Infection
Wound
Healing
Gangrene
Formation
Amputation
Glycosuria
Osmotic
Diuresis
Urine
Output
Polyuria
Cellular
Starvation
Sensation of
hunger
Polyphagia
Lipolysis
Accumulation
of by product
Fatty
Acid
s
Ketones
Atherosclerosis
Micropathy
Metabolic
acidosis
CHON breakdown
Muscle Wasting and poor
wound healing
Toxic to Brain tissue
Acetone
Breath
Ketonuria
Diabetic
Ketoacidosis

Macropathy
CVA, MI, PVD Retinopathy Nephropathy
Loss of vision
Blindness
ESRD
Neuropathy
Loss of Sensation
Tingling/numbness
Weakness
Diabetes Mellitus Type 2