tendons, and ligaments of the skeletal system are all connective tissues. Their characteristics are largely determined by the composition of their extracellular Yellow marrow consists mostly of adipose matrix. Tissue Red marrow consists of blood-forming cells and is the only site of blood formation in adults. Children’s bones have proportionately more red marrow than do Type of connective tissue. adult bones because, as a person ages, red marrow is Proteoglycans- are large molecules consisting of mostly replaced by yellow marrow. polysaccharides attached to core proteins Periosteum- Most of the outer surface of bone is Cartilage- contains collagen and proteoglycans. covered by dense connective tissue The matrix always contains collagen, ground substance, Endosteum- is a thin vascular membrane of connective and other organic tissue that lines the inner surface of the bony tissue that Collagen-is a tough, ropelike protein.it makes forms the medullary cavity of long bones cartilage tough, Histology of Bone Four categories of bone The periosteum and endosteum contain osteoblasts -Long bones are longer than they are wide. Most which function in the formation of bone, as well as in of the bones of the upper and lower limbs are long the repair and remodeling of bone. bones. Osteoclasts- bone-eating cells are also present and - Short bones are approximately as wide as they are contribute to bone repair and remodeling by removing long; examples are existing bone. the bones of the wrist and ankle. Lamellae- Bone is formed in thin sheets of extracellular matrix - Flat bones have a relatively thin, flattened shape. called lamellae Examples of flat bones are certain skull bones, the Lacunae- with osteocytes located between the ribs, the scapulae (shoulder blades), and the sternum. lamellae within spaces called lacunae. a cavity or - Irregular bones include the vertebrae and facial depression Canaliculi- little canal bones, which have shapes Compact bone- is mostly solid matrix and cells. that do not fit readily into the other three categories. Spongy bone, or cancellous bone, consists of a lacy network Structure of a Long Bone of bone with many small, marrow-filled spaces. Diaphysis- long bone consists of a central shaft, Compact Bone Epiphysis- the end part of a long bone, initially growing Compact bone (figure 6.3) forms most of the diaphysis of a separately from the shaft.\ long bone and the thinner surfaces of all other bones. articular cartilage covers the ends of the epiphyses Osteons- Each osteon consists of concentric rings of lamellae where the bone articulates (joins) with other bones. surrounding a central canal. epiphyseal plate, or growth plate- composed of cartilage, between each epiphysis and the diaphysis The epiphyseal plate is where the bone grows in length Epiphyseal line- When bone growth stops, the cartilage of each epiphyseal plate is replaced by bone and becomes an epiphyseal line Bones contain cavities, such as the large medullary cavity in the diaphysis, as well as smaller cavities in the epiphyses of long bones and in the interior of other bones. Spongy Bone Spongy bone- is located mainly in the epiphyses of long bones.Spongy bone consists of delicate interconnecting rods or plates of bone called trabeculae Trabeculae-Spongy bone consists of delicate interconnecting rods or plates of Bone. which resemble the beams or scaffolding of a building. Like scaffolding, the trabeculae add strength to a bone without the added weight that would be present if the bone were solid mineralized matrix. Bone Ossification Ossification-( to make) is the formation of bone by osteoblasts. After an osteoblast becomes completely surrounded by bone matrix, it becomes a mature bone cell, or osteocyte. Skull The 22 bones of the skull are divided into those of the braincase and those of the face. braincase, which encloses the cranial cavity, consists of 8 bones that immediately surround and protect the brain. facial bones- 14 bones form the structure of the face. Thirteen of the facial bones are rather solidly connected to form the bulk of the face. The mandible, however, forms a freely movable joint with the rest of the skull. There are also three auditory ossicles (in each middle ear (six total).