Abagu, Cambel, David, Latumbo, Milliam, Okurji 10) Which is one of the functions of plasma protein

Group 4 Ph 3A – Protein Binding binding?

a) Functions as an Electrolyte
Latumbo, Nzy Nicole b) Coagulation of blood
c) Transport different type of amino acids
1.Proteins interact with small molecules. d) H- Bonding
2. Interfacial phenomenon that results of attraction 11) If albumin becomes saturated, then these drugs will
between nonpolar groups with water molecules. bind to?
3. Occur between charge amino acids with oppositely a) Plasma protein
charge ligand molecules. b) Lipoprotein
4. Dipole-dipole, dipole induced dipole, dispersion c) Glycoprotein
forces d) Protein Ligand
12) Basic drugs will bind to what?
Choices: A. Van der Waals interactions a) Molar concentration
B. Hydrophobic interaction b) Polymer Complexes
C. Electrostatic interactions c) Neutral protein
D. H-bonding d) Alpha-acid glycoprotein, and lipoprotein

Okurji, Charles Answers: A.200, B. Coagulation of blood, C.

Lipoprotein, D. Alpha -1acid glycoprotein, and
5)The interaction between small molecules such as drugs lipoprotein
and protein?
a) protein ligand interaction David, Ida Louise P.
b) gumming
c) sticking Choices:
d) NOTA A. Spectroscopic Method
6) which of the following is/are importance of protein B. Equilibrium Dialysis
ligand interaction C. Ultracentrifugation
a) in drug binding to receptor for pharmacological D. Gel Filtration
activities
b) enzyme-substrate interaction in catalyst 13) Involves separation of compounds according to size
c) antibody -antigen recognition difference or MW.
d) AOTA Answer: B
14) “Ultrafiltration”
For the following questions, answer Answer: C
A-if only statement 1 is correct 15) First adapted for measurement of protein ligands
B-if only statement 2 is correct interaction.
C-if both statement 1&2 are correct Answer: D
D-if both statements are wrong 16) Separated with the aid of big centrifugal force.
Answer: C
7)protein ligand interactions are the interactions between
small molecules such as drugs and protein. They are not Milliam, Jade T.
important in enzyme- substrate interaction catalysis.
Answer- A
8)protein ligand interactions are important as antibody- Choices:
antigen recognition. They interact between drugs and A. Electrophoresis
protein in plasma. Answer- C B. Ultrafiltration
C. Chromatography
Campbel, Shane Paul O. D. Ultracentrifugation
E. Equilibrium Dialysis
9) Human plasma is composed of how many proteins? F. Spectrophotometry
a) 200 G. NOTA
b) 250
c) 150 B_ 5: A method in which a specimen passes through a
d) 100 medium which allows small molecules to pass but holds
back larger molecules.
F_6: A method to measure how much a chemical
substance absorbs light by measuring the intensity of
light as a beam of light passes through sample solution.

D_7: A rapid rotation which separate particles, which is

used in determining size and weight of molecules.

G_8: For the investigation of specimen using a multitude

of wavelengths of the spectrum such as infrared, x-ray
and visible light.

E_9: A Method where solutions are separated by a

semipermeable membrane.