Homework 5

 Use Data_HW5.xlsx for the data

 follow the 10-step hypothesis testing procedure; in the step of “calculation of test statistic”, use
MATLAB to obtain the ANOVA table and find the results accordingly. (prob VI does not need
10 steps)
 Before you start, make sure you can tell 1-way, 2-way or n-way ANOVA is going to be used.
 If the post analysis is needed, use MATLAB function ‘multcompare’.
 Attach all MATLAB results/figures/tables and draw your conclusion accordingly.

Problem I (10 pts)

Nine laboratory animals were infected with a certain bacterium and then immunosuppressed. The
mean number of organisms later recovered from tissue specimens was 6.5 (coded data) with a
standard deviation of 0.6. Can one conclude from these data that the population mean is greater
than 6? Let α =0.05. What assumptions are necessary (step 2)?

Problem II (20 pts)

Packed cell volume determinations were made on two groups of children with cyanotic
congenital heart disease. The sample sizes and variances were as follows:

Group n s2
1 10 40
2 16 84

1) Does the data provide sufficient evidence that the population 1 has variance greater than
30? Let α=0.05.
2) Does the data provide sufficient evidence that the population 2 has variance greater than
60? Let α=0.05.

Problem III (15 pts)

Ilich-Ernst et al. investigated dietary intake of calcium among a cross section of 109 healthy
women ages 20–88. The researchers formed four age groupings as follows:
Group A, 20.0–45.9 years;
Group B, 46.0–55.9 years;
Group C, 56.0–65.9 years;
Group D, over 66 years.
Calcium from food intake was measured in mg/day. The data below are consistent with summary
statistics given in the paper.
 (a) Do these data provide sufficient evidence to indicate a difference in mean calcium intake
among age groups?
(b) If the null hypothesis is rejected, perform the post analysis to identify which pair(s) of
age groups have different mean calcium intake?

Problem IV (15 pts)

One of the purposes of an investigation by Porcellini et al. was to investigate the effect on CD4 T
cell count of administration of intermittent interleukin (IL-2) in addition to highly active
antiretroviral therapy (HAART). The following table shows the CD4 T cell count at baseline and
then again after 12 months of HAART therapy with IL-2. Do the data show, at the .01 level, a
significant change in CD4 T cell count?

Problem V (20 pts)

The data shows the vital capacity measurements (cm3) of 60 adult males classified by occupation
(A-D) and age group (1-3)
(a) Can we conclude based on these data that there is a difference among occupations?
(b) Can we conclude based on these data that there is a difference among age groups?
(c) Can we conclude that there is interaction between occupations and age groups?

Problem VI (20 pts)

Fiddler crabs are so called because males have a greatly enlarged “major” claw, which is used to
attract females and to defend a burrow. Darnell and Munguia (2011) recently suggested that this
appendage might also act as a heat sink, keeping males cooler while out of the burrow on hot
days. To test this, they placed four groups of crabs into separate plastic cups and supplied a
source of radiant heat (60-watt light bulb) from above. The four groups were intact male crabs;
male crabs with the major claw removed; male crabs with the other (minor) claw removed
(control); and intact female fiddler crabs. They measured body temperature of crabs every 10
minutes for 1.5 hours. These measurements were used to calculate a rate of heat gain for every
individual crab in degrees C/log minute. Rates of heat gain for all crabs are provided below.
Female: 1.9, 1.6, 1.4, 1.1, 1.6, 1.8, 1.9, 1.7, 1.5, 1.8, 1.7, 1.7, 1.8, 1.7, 1.8, 2.0, 1.8, 1.7, 1.6, 1.6,
1.5
Intact male: 1.9, 1.2, 1.0, 0.9, 1.4, 1.0, 1.3, 1.4, 1.1, 1.0, 1.4, 1.2, 1.4, 1.4, 1.5, 1.5, 1.1, 1.4, 1.3,
1.3, 1.3
Male minor removed: 1.2, 1.0, 0.9, 0.8, 1.2, 0.9, 1.1, 1.1, 1.3, 1.3, 1.3, 1.1, 1.4, 1.5, 1.4, 1.4,
1.2, 1.4, 1.3, 1.2, 1.4
Male major removed: 1.2, 0.9, 1.4, 1.2, 1.2, 1.6, 1.9, 1.4, 1.4, 1.4, 1.6, 1.4, 1.7, 1.3, 1.5, 1.2,
1.3, 1.6, 1.5, 1.5, 1.5
(a) Show these data in a graph. What trends are suggested? Show 4 histograms in 1 plot, you
can decide all parameters (titles, legends, labels, bin width, the number of bins, etc.) as
long as you present the data efficiently.
(b) Use ANOVA to test whether mean rate of heat gain differs among groups. You do not
need to follow the 10 steps for this problem. Just show the null and alternative
hypothesis, ANOVA table from MATLAB/Minitab results, and your interpretation of the
F number. Then, your final result in your own words.
(c) Assuming the main comparison of interest, which was identified before carrying out the
experiment, was to test for a difference between the two male groups “Major removed”
and “Minor removed.” Run a Tukey-Kramer multiple comparisons of means. What
result can you have? Show the table and plots. Draw your final conclusion.  

Rubric:

Question 1: ( _____ / 10 points)

10 steps 1 point each.
Question 2 : ( ______ / 20 points)
10 steps 1 point each. 2 questions, 20 points in total.
Question 3 ( ____ / 15 points)
10 steps, 1 point each in a.
5 points for b. show result plot and your conclusion.
Question 4 ( ____/ 15 points)
(a) ( __/10) (Each step of 10 step hypothesis testing)
(b) ( __/5) (Using the proper procedure)

Question 5: ( ____ / 20 points)

For this problem, (1), (2), (3) share majority of the steps. Only a few steps during the ANOVA
process are unique.

Question 6: ( ____ / 20 points)

(a) Histograms and description of the trend. 5 points
(b) Hypothesis, ANOVA table, conclusion, 10 points
(c) Test results and conclusion. 5 points