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PATHOLOGY

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MEAN MPL FOR THIS EXAM: 76.89
CEBU INSTITUTE OF MEDICINE 17. Thymic hypoplasia is a feature of:
A. Sjogren’s syndrome C. Di George syndrome
1. The morphologic pattern of necrosis in myocardial infarction B. SLE D. Wiskott-Aldrich syndrome
is :
A. Coagulative necrosis 18. CREST syndrome is related to:
B. Liquefactive necrosis A. Hyper-IgM syndrome
C. Fat necrosis B. Bruton’s hypogammaglobulinemia
D. Caseation necrosis C. scleroderma, localized
D. preeclampsia
2. The most common cause of fatty change in the liver is:
A. CC14 poisoning C. Diabetes mellitus 19. Which is not oncogenic?
B. Alcohol abuse D. Protein malnutrition A. Human papilloma virus C. Herpes virus
B. Hepatitis B virus D.Epstein-Barr virus
3. The cellular adaptation that occurs in the respiratory tract of
a chronic cigarette smoker is: 20. Which is not a malignant tumor?
A. Hyperplasia C. Metaplasia A. Lymphoma C. Leiomyosarcoma
B. Hypertrophy D. Atrophy B. Melanoma D. Hamartoma

4. The first manifestation of almost all forms of cell injury is: 21. Features of malignant cells, EXCEPT:
A. Fatty change C. Dystrophic caicification A. Hyperchromatic and pleomorphic nuclei
B. Hyaline change D. Cellular swelling B. Tumor giant cell
C. Anaplasia
5. Refers to the focal accumulation of cholesterol-laden D. No exception
macrophages in the lamina propia of the gallbladder:
A. Steatosis C. Xanthoma 22. Leading type of cancer in men:
B. Cholesterolosis D. None of these A. skin cancer C. lung cancer
B. prostate cancer D. testicular cancer
6. Which is granulomatous disease?
A. Leprosy C. Tuberculosis 23. Which of the following refers to the degree of cellular
B. Schistosomiasis D All of these differentiation of tumor cells?
A. Stage C. grade
7. Antipyretics inhibit inflammatory process by inhibiting: B. Metastasis D. Doubling time
A. Cyclooxygenase pathway
B. Dismutase 24. Warthin-finkeldey cells are seen in:
C. Lipooxygenase pathway A. Chicken pox C. herpes simplex infection
D. A & C B. Mumps D. Measles

8. Chronic granulomatous disease is characterized by impaired 25. Ghon complex is associated with:
microbicidal ability due to: A. Leprosy C. HIV infection
A. NADH oxidase deficiency B. Tuberculosis D. all of these
B. T cell immunodeficiency
C. Lack of adhesion molecules 26. Ultraviolet rays are implicated in:
D. Complement deficiency A. Gastric cancer
B. Urinary bladder cancer
9. Increased susceptibility to infection in diabetic patients is due C. Squamous cell carcinoma, skin
to: D. Bronchogenic carcinoma
A. Deficiency of emigration and chemotaxis of
neutrophils 27. Trenchfoot is due to:
B. B cell deficiency A. Blast injury C. greenhouse effect
C. Impaired microbicidal activity B. Mercury poisoning D. Hypothermia
D. Nitric oxide deficiency
28. The disease of the displaced child:
10. Which is not associated with chronic inflammation? A. Marasmus C. Keshan diseae
A. Fibrosis B. Kwashiorkor D. Bulimia
B. Neutrophilic infiltration
C. Granuloma 29. Bends and chokes are features of:
D. Macrophages and epithelioid cells A. Fat embolism
B. Paradoxic embolism
11. Redness is: C. air embolism
A. Calor C. Dolor D. amniotic fluid embolism
B. Tumor D. None of these
30. Risk factors for atherosclerosis:
12. Brown atrophy of the heart in aging is due to: A. Cigarette smoking C. Diabetes
A. Amyloid deposits C. Hemosiderin pigments B. Hypertension D. All of these
B. Lipofuscin D. Basophilic degeneration
31. Which typically presents with headache and facial pain?
13. 47, XXY is : A. Temporal arteritis
A. Cri-du-chat syndrome B. Polyarteritis nodosa
B. Klinefelter’s syndrome C. Kawasaki disease
C. Turner’s syndrome D. Takayasu arteritis
D. Normal female
32. Rib-notching on chest x-ray is a finding in:
14. Tall stature and arachnodactyly are characteristic of: A. Tetralogy of Fallot C. aortic coarctation
A. Ehlers-Danlos syndrome B. Patent ductus arteriosus D. all of these
B. Trisomy 21
C. Prader-Willi syndrome 33. Mid-systolic click can be heard in:
D. Marfan syndrome A. Mitral valve prolapse
B. Atrial septal defect
15. Transplant rejection is which type of hypersensitivity C. Ventricular septal defect
reaction? D. Carcinoid heart disease
A. type I C. type III
B. type II D. type IV 34. Coronary artery spasm is noted in:
A. Stable angina C. unstable angina
16. Which is NOT a major (Jones) criterion of rheumatic fever? B. Prinzmetal angina D. All of these
A. Carditis
B. erythema marginatum 35. Troponin rises after:
C. arthralgia A. Acute myocardial infarction C. Pancreatitis
D. sydenham’s chorea B. Angina pectoris D. Liver necrosis
PATHOLOGY
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B. Emphysema D. All of these
36. Hemoglobin H disease is a variant of:
A. Alpha-thalassemia C. Beta-thalassemia 53. Intrinsic asthma is initiated by:
B. Sickle cell disease D. Immunohemolytic anemia A. Pulmonary viral infection C. Inhaled irritants
B. Aspirin ingestion D. All of these
37. Hemolysis with antimalarial drug administration can occur in:
A. Iron deficiency anemia 54. True of adult respiratory distress syndrome, EXCEPT:
B. G6PD deficiency A. Diffuse alveolar capillary damage
C. mycosis fungoides B. B. Deficiency of pulmonary surfactant
D. Pernicious anemia C. Noncardiogenic pulmonary edema
D. No exception
38. Pancytopenia is a feature of:
A. Paroxysmal nocturnal hemoglobinuria 55. Failure of involution of the vitelline duct leads to:
B. Hereditary spherocytosis A. Herniation C. Meckel’s diverticulum
C. Folate deficiency B. Volvulus D. All of these
D. D. Aplastic anemia
56. One segment of the small intestine constricted by a wave of
39. Which can lead to DIC? peristalsis suddenly became telescoped into the distal
A. Septic abortion C. Gram negative sepsis segment happen in:
B. Extensive surgery D. All of these A. Intussusception C. Volvulus
B. Diverticula D. Strangulation
40. Which causes relative polycythemia?
A. High-altitude living 57. Absence of ganglion cells in the large bowel leading to
B. Renal cell carcinoma functional obstruction with colonic dilatation:
C. Gaisbock syndrome A. Achalasia C. Hirschsprung disease
D. Cyanotic heart disease B. Ulcerative colitis D. Angiodysplasia

41. The most common cause of microcytic, hypochromic anemia 58. A portion of the abdominal wall fails to form altogether with
is: extrusion of the intestine:
A. Vitamin B12 deficiency A. Omphalocele C. Meckel’s diverticulum
B. Iron deficiency B. Herniation D. Gastroschisis
C. Pure red cell aplasia
D. Leukemia 59. Complications of colonic diverticula, EXCEPT:
A. Obstruction C. Bleeding
42. Evaluates the intrinsic coagulation pathway and is most B. Peritonitis D. Malignancy
commonly used to monitor heparin therapy:
A. Prothrombin time C. APTT 60. Causes of hematemesis, EXCEPT;
B. Bleeding time D. Clotting time A. Mallory-Weiss syndrome
B. Esophageal Varices
43. Defective platelet aggregation occur in: C. Peptic ulcer
A. Glanzmann’s thrombasthenia D. Barrett’s esophagus
B. Henoch-Schonlein purpura
C. Bernard-Soulier syndrome 61. Nutmeg liver is due to:
D. vonWillebrand disease A. Inflammation C. congestion
B. Neoplasm D. cirrhosis
44. Which is not a cause of eosinophilic leukocytosis?
A. Allergic disorders C. Viral infection 62. Bronze diabetes refers to:
B. Parasitism D. drug reaction A. Wilson’s disease
B. Budd-Chiari syndrome
45. M spike on protein electrophoresis is noted in: C. Primary hemochromatosis
A. Multiple myeloma C. Hodgkin’s disease D. Reye’s syndrome
B. Burkitt’s lymphoma D. All of these
63. There is conjugated hyperbilirubinemia in:
46. Auer rods are diagnostic of: A. Dubin-Johnson’s syndrome
A. Acute myeloblastic leukemia B. Gilbert’s syndrome
B. Chronic lymphocytic leukemia C. Rotor’s syndrome
C. Acute lymphoblastic leukemia D. A & C
D. Chronic myelocytic leukemia
64. Most common predisposing cause of ascending cholangitis:
47. Reed-Sternberg cells are diagnostic of: A. Acute pancreatitis C. Choledocholithiasis
A. non-Hodgkin’s lymphoma B. Benign stricture D. Tumors
B. Polycythemia vera
C. Myelodysplastic syndrome 65. Rokitansky-Aschoff sinuses are seen in:
D. None of these A. Rheumatic heart disease
B. Chronic Cholecytitis
48. Variants of Langerhans cell histiocytosis include the ff., C. Biliary atresia
EXCEPT: D. Criggler-Najjar syndrome
A. Eosinophilic granuloma
B. Myelofibrosis with myeloid metaplasia 66. Etiologic factors in acute pancreatitis include the ff., EXCEPT:
C. Letterer-Siwe disease A. Alcoholism C. Gall stones
D. Hand-Schuller disease B. Genetic D. No exception

49. Cor pulmonale is associated with: 67. Late complications of chronic pancreatitis include the ff.,
A. L-sided heart failure C. Both A & B EXCEPT:
B. R-sided heart failure D. Neither A nor B A. Diarrhea (Malabsorption) C. Diabetes
B. Pseudocyst D. Hemorrhage
50. Presence of rheumatoid nodules and pneumoconiosis
constitutes: 68. Azotemia, hypocalcemia and hyperparathyroidism are
A. Goodpasture’s syndrome associated with:
B. Mickulicz syndrome A. Acute renal failure
C. Loeffler’s syndrome B. Chronic renal failure
D. Caplan syndrome C. Nephretic syndrome
D. Nephrotic syndrome
51. May produce pulmonary hypertension, EXCEPT:
A. Mitral stenosis C. Emphysema 69. Associated with Proteus infection, also called Staghorn
B. Recurrent pulmonary emboli D. No exception calculi:
A. Calcium stones C. Struvite stones
52. Low levels of serum alpha-1 antitrypsin can cause: B. Uric acid stones D. None of these
A. Bronchiectasis C. Chronic bronchitis
PATHOLOGY
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70. Which is not associated with diabetic nephropathy?
A. Kimmelsteil-Wilson disease 88. Most frequent type of hyperfunctioning pituitary adenoma:
B. Acute pyelonephritis A. Somatostatinoma
C. Papillary necrosis B. Corticotroph adenoma
D. Renal artery stenosis C. Prolactinoma
D. Thyrotroph adenoma
71. IgA deposit in mesangium can be appreciated by:
A. Immunofluorescence microscopy 89. Chronic adrenal insufficiency leads to:
A. Waterhouse-Friederichsen syndrome
B. Electron microscopy
C. Light microscopy
B. Addison’s disease
D. All of these
C. Cushing’s syndrome
D. Hyperaldosteronism
72. Nephritic factor, dense deposits are related to:
A. Membranoproliferative glomerulonephritis
90. A cause of primary osteoporosis:
B. Lipoid nephrosis
A. Post menopausal
C. Focal segmental glomerulonephritis
B. Hyperparathyroidism
D. Acute post-streptococcal glomerulonephritis
C. Malnutrition
D. Rheumatologic disease
73. Maturation index determination is done with:
91. A genetic derangement in epiphysial cartillagenous growth
A. Paps smear C. Tzanck smear
resulting in dwarfism:
B. Gram stain D. All of these
A. Osteogenesis imperfecta C. Achondroplasia
B. Osteopetrosis D. Paget’s disease
74. Orifice of the prepuce is too small to permit its normal
retraction:
92. Failure in bone mineralization resulting in exist unmineralize
A. Epispadias C. Paraphemosis
matrix and abnormally wide osteioid seems occur in:
B. Chondyloma D. None of these
A. Rickets C. Osteomalasia
B. Ostitis deformans D. A & C
75. Positively identified as cause of the cancer of the cervix:
A. Cytomegalovirus C. Herpes virus
93. Saber shin is due to:
B. Candidiasis D. Human papilloma virus
A. Rickets C. Syphilis
B. Pyogenic osteomyelitis D. Pott’s disease
76. Features of toxemia of pregnancy, EXCEPT:
94. Chronic tophaceous gout and arthritis occur in:
A. Anemia C. Hypertension
A. Hyperuresimia C. Hyperglycemia
B. Edema D. Proteinuria
B. Hypercalcemia D. Hyperproteinemia
77. Hormone used to determine pregnancy:
95. Calcium pyrophosphate deposition occur in:
A. FSH C. Progesterone
A. Gout C. Pseudogout
B. Beta-HCG D. All of these
B. Rheumatoid arthritis D. All of these
78. Not seen in secretory endometrium:
96. Degenerative joint disease is:
A. Mitosis and gland proliferation
A. Rheumatoid arthritis C. Gouty arthritis
B. Subnuclear vacuole
B. Marie-Strumpel disease D. Osteoarthritis
C. Secretion
D. Prominent spiral arteriole
97. Infection of CNS in neonate during delivery occur in which
condition:
79. The most common complication of gonorrhea in women:
A. Syphilis
A. Endometriosis
B. Herpes simplex condition
B. Endometritis
C. Gonorrhea
C. Vulvovaginitis
D. Chlamydial infection
D. Pelvic inflammatory disease
98. CSF albuminucytologic dissociation occur in:
80. All are important in semen analysis, EXCEPT:
A. Multiple sclerosis C.
A. Sperm count C. Volume
B. Pyogenic meningitis
B. Morphology D. Motility
C. Guillain- Barre syndrome
D. Subarachnoid hemorrhage
81. Most common site of endometriosis:
A. Ovaries C. Peritonium
99. The counterpart of mad cow disease in human is:
B. Uterine ligament D. Rectovaginal septum
A. Creutzfetldt-Jacob disease
B. Progressive multifocal leucoencephalopathy
82. Clinical indicator of hyperestrinism:
C. Rabies
A. Mastitis C. Nipple inversion
D. None of these
B. Fat necrosis D. Gynecomastia
100. Gemistocytic astrocytes are noted in:
83. Morphologic patterns of fibrocystic change of the breast,
A. Hypoglycemia C. Damaged brain
EXCEPT:
B. Ethanol abuse D. All of these
A. Adenosis C. Fibrosis
B. Cyst formation D. Papilloma

84. Acquired retraction of the nipple occur in:


A. Lactation C. Breast cancer
B. Silicon breast implant D. All of these

85. There is insulin resistance in:


A. Type 1 diabetes mellitus C. A & B
B. Type 2 diabetes mellitus D Neither A nor B

86. Ischemic necrosis of the anterior pituitary leads to:


A. Cushing’s disease C. Sheehan syndrome
B. SIADH D. Cretinism

87. Believe to be cause by viral infection or post viral


inflammatory process:
A. Subacute granulomatous thyroiditis
B. Hashimoto’s thyroiditis
C. Reidel thyroiditis
D. All of these

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